夏文芳
重症
主任医师，副教授，硕士研究生导师
主任医师，副教授，硕士研究生导师
导师介绍
| 姓名 | 夏文芳 |
| 出生年月 | 1981年11月 |
| 单位 | 武汉大学人民医院重症医学一科 |
| 所属学科 | 临床医学-重症医学 |
| 职务、职称及头衔 | 主任医师，副教授，硕士研究生导师 |
| 59267089@qq.com | |
| 联系方式 | 027-88041911转81075或15972061317 |
| 研究方向 | 1.脓毒症肺损伤；2.脓毒症微循环功能障碍与器官功能损伤；3.危重症脏器功能保护 |
| 个人简介 | 已从事急危重症的临床救治和研究工作14年，主要研究方向脓毒症肺损伤以及危重症器官功能保护等。曾于2011年赴美国Oklahoma大学医学中心学习危重症前沿基础研究，包括脓毒症时组织器官血管内皮渗透性的机制及调控研究。先后主持国家自然科学基金2项，承担国家自然科学基金和湖北省自然科学基金项目等共7项，已在Int J Cardiol、Pediatr Cardiol、Yonsei Med J、J Cardiovasc Electrophysiol、Mol Cell Biochem、中华医学杂志、中华急诊医学杂志和中华流行病学杂志等国内外学术期刊以第一作者发表论文20余篇。研究成果获湖北省科技进步一等奖（2013年）、湖北省科技进步二等奖（2015年）和武汉市科技进步一等奖（2013年），武汉市科技进步二等奖（2015年）各1项；2016年华夏医学科技奖三等奖。 |
| 学术任职与荣誉 | 武汉市中青年医学骨干人才；武汉大学人民医院第5轮青年重点人才；湖北省病理生理学会危重病医学专业委员会常务委员；湖北省微循环学会重症专业委员会常务委员；湖北省病理生理学会危重病医学专业青年委员会委员；湖北省微循环学会模拟医学专业委员会委员；中国人体健康科技促进会人体器官与组织捐献专业委员会委员；武汉市临床重点专科评审专家；武汉大学人民医院优秀教学秘书；武汉大学人民医院优秀指导教师；武汉大学人民医院优秀共产党员称号 |
| 教育履历 |
2000.09-2005.06武汉大学医学院临床医学专业本科生获学士学位 2005.09-2007.06武汉大学第一临床学院麻醉学硕士研究生获硕士学位 2010.09-2013.11武汉大学第一临床学院内科学博士研究生获博士学位 |
| 工作履历 |
2007.07-2009.11.广东医学院附属医院麻醉科住院医师 2009.11-2011.12武汉大学人民医院重症医学科住院医师 2012.01-2014.11武汉大学人民医院重症医学科主治医师 2014.12-至今 武汉大学人民医院重症医学科副主任医师 |
| 成果获奖 |
1.《心肌重构的发病基础与临床防治》2013年获湖北省以及武汉市科技进步二等奖各一项 2.《心脏大血管手术所致多脏器损伤的机制与防治探讨》获2015年湖北省科技进步二等奖；2016年武汉市科技进步二等奖；2016年华夏医学科技奖三等奖 |
| 代表性论著 |
1. Xia
W, Liu Y. Targeted ablation of cardiac sympathetic neurons: A promising
approach to prevent sudden cardiac death, Int J Cardiol, 2016, 202:425-426.
(SCI二区，IF: 4.638) 2. Xia WF, Liu Y, Zhou QS, Tang QZ, Zou HD, Protective effect of propofol and its relation to postoperation recovery in children undergoing cardiac surgery with cardiopulmonary bypass, Pediatr Cardiol, 2011;32(7):940-6. (SCI收录，IF:1.452) 3. Xia WF, Liu Y, Zhou QS, Tang QZ, Zou HD, Comparison of the effects of propofol and midazolam on inflammation and oxidase stress in children with congenital heart disease undergoing cardiac surgery, Yonsei Med J, 2011;52(2):326-32. (SCI收录，IF:1.154) 4. Xia WF, Zhang HM , Pan Z, Li G, Zhou QS , Hu D, Liu Y, Inhibition of MRP4 alleviates sepsis-induced acute lung injury in rats, International Immunopharmacology,2019, 72 :211–217.( SCI收录，3区IF:3.118) 5. Xia WF,Guang Li, Zhou Pan, Qingshan Zhou, Hypercapnia attenuates ventilator-induced lung injury through vagus nerve activation, Acta Cir Bras,2019,34(9): e201900902( SCI收录，4区IF:1.118) 6. Wenfang Xia, Zhou Pan, Huanming Zhang, Qingshan Zhou, Yu Liu, Inhibition of ERRα Aggravates Sepsis-Induced Acute Lung Injury in Rats via Provoking Inflammation and Oxidative Stress. Oxidative Medicine and Cellular Longevity,Volume 2020, Article ID 2048632, 9 pages. ( SCI收录，2区IF:5.076) 7. Wei Hu ,Hui Feng, Xiaoyu Xu,Xin Huang, Xingyue Huang,Wenwei Chen,Lidan Hao,Wenfang Xia, Long noncoding RNA FOXD2-AS1 aggravates hepatocellular carcinoma tumorigenesis by regulating the miR-206/MAP3K1 axis. Cancer Medicine. 2020;9:5620–5631.( SCI收录，3区IF:3.491)通讯作者 |
| Name | Wenfang Xia |
| Date of birth | November，1981 |
| Department | Critical Care Medicine Department，Renmin Hospital,Wuhan University. |
| Title | Chief Physician, Master Tutor |
| 59267089@qq.com | |
| TEL | 027-88041911-81075or 15972061317 |
| Research Direction |
1.
Sepsis and lung injury;2. Sepsis microcirculation dysfunction and organ
function damage;3. Organ function protection in critically ill patients |
| Personal Profile | She has been engaged in clinical treatment and research of acute and critical diseases for 14 years, and her main research areas are sepsis lung injury and organ function protection of critical diseases.In 2011, she went to Oklahoma University Medical Center to study frontier basic research in critical disease, including the mechanism and regulation of vascular endothelial permeability in tissues and organs during sepsis.Successively presided over by the national natural science fund item 2, bear the national natural science foundation of China and hubei province natural science fund projects, etc. A total of seven, have been Int J Cardiol, Pediatr Cardiol, Yonsei Med J, J Cardiovasc Electrophysiol, Mol Cell Biochem, the Chinese medical journal, Chinese journal of emergency medicine and the journal epidemiology at home and abroad more than 20 academic journal papers as the first author.Her research achievements have been awarded the First Prize of Science and Technology Progress of Hubei Province (2013), the Second Prize of Science and Technology Progress of Hubei Province (2015), and the First Prize of Science and Technology Progress of Wuhan City (2013), and the Second Prize of Science and Technology Progress of Wuhan City (2015).Third Prize of China Medical Science and Technology Award in 2016. |
| Selected Publications |
1. Xia
W, Liu Y. Targeted ablation of cardiac sympathetic neurons: A promising
approach to prevent sudden cardiac death, Int J Cardiol, 2016, 202:425-426.
(SCI二区，IF: 4.638) 2. Xia WF, Liu Y, Zhou QS, Tang QZ, Zou HD, Protective effect of propofol and its relation to postoperation recovery in children undergoing cardiac surgery with cardiopulmonary bypass, Pediatr Cardiol, 2011;32(7):940-6. (SCI收录，IF:1.452) 3. Xia WF, Liu Y, Zhou QS, Tang QZ, Zou HD, Comparison of the effects of propofol and midazolam on inflammation and oxidase stress in children with congenital heart disease undergoing cardiac surgery, Yonsei Med J, 2011;52(2):326-32. (SCI收录，IF:1.154) 4. Xia WF, Zhang HM , Pan Z,, Li G, Zhou QS , Hu D, Liu Y, Inhibition of MRP4 alleviates sepsis-induced acute lung injury in rats, International Immunopharmacology,2019, 72 :211–217.( SCI收录，3区IF:3.118) 5. Xia WF,Guang Li, Zhou Pan, Qingshan Zhou, Hypercapnia attenuates ventilator-induced lung injury through vagus nerve activation, Acta Cir Bras,2019,34(9): e201900902( SCI收录，4区IF:1.118) 6. Wenfang Xia, Zhou Pan, Huanming Zhang, Qingshan Zhou, Yu Liu, Inhibition of ERRα Aggravates Sepsis-Induced Acute Lung Injury in Rats via Provoking Inflammation and Oxidative Stress. Oxidative Medicine and Cellular Longevity,Volume 2020, Article ID 2048632, 9 pages. ( SCI收录，2区IF:5.076) 7. Wei Hu ,Hui Feng, Xiaoyu Xu,Xin Huang, Xingyue Huang,Wenwei Chen,Lidan Hao,Wenfang Xia, Long noncoding RNA FOXD2-AS1 aggravates hepatocellular carcinoma tumorigenesis by regulating the miR-206/MAP3K1 axis. Cancer Medicine. 2020;9:5620–5631.( SCI收录，3区IF:3.491)通讯作者 |
武汉大学人民医院
湖北省人民医院