武汉大学人民医院湖北省人民医院

院内导航

毛善平 神经病学
科副主任，主任医师，硕士生导师

A+ A-

导师介绍

姓名	毛善平
出生年月	1964年10月
单位	武汉大学人民医院神经内科
所属学科	神经病学
职务、职称及头衔	科副主任，主任医师，硕士生导师
E-mail	maospzy@163.com
联系方式	027-88041911转82221或18602716397
研究方向	1.痴呆与认知神经心理学研究 2.帕金森病与运动障碍疾病
个人简介	主要于神经心理学领域研究三十余年，获卫生部科技进步二等奖1项，卫生部全国中青年优秀论文二等奖1项，湖北省科技进步二等奖1项，湖北省优秀论文奖多项。参编著作5部，发表论文100余篇，其中SCI论文总影响因子20分以上。主持及参与省部级项目9项，主持国家自然科学基金1项，参与国家“863计划”子项目1项，参与国家重点研发计划项目1项，参与国家“985工程”二期拓展平台2个平台的研究，承担国家“十一五”科技支撑计划研究的研究（分中心负责人），承担国家“十二五”及国家科技部重大专项研究各2项。参与湖北省重点研发计划1项。主持武汉市科技攻关重点项目1项。已培养硕士生39名，目前正在培养的硕士生3名。
学术任职与荣誉	中华医学会神经病学分会神经心理学与行为神经病学学组委员中国医师协会睡眠医学专家委员会委员中国卒中学会脑卒中康复分会委员中国老年医学会认知分会委员中国睡眠研究会睡眠障碍专业委员会委员中国老年保健医学会老年认知心理分会委员中国康复技术促进会言语听力康复治疗专业委员会委员中国老年学和老年医学学会认知与脑健康分会委员中国老年医学会认知分会神经心理量表评估委员会委员中华神经科杂志编辑委员会审稿人《中国神经再生研究》英文版编委湖北省中西医结合神经内科学会副主任委员湖北省心理学会临床心理学专业委员会常委武汉市疼痛学会副主任委员湖北省神经内科学会委员武汉市神经内科学会委员，痴呆与神经心理学组副组长帕金森病与运动障碍学组副组长《卒中与神经疾病杂志》副总编辑《武汉大学学报》医学版审稿专家
教育履历	1979.09-1984.06武汉大学第二临床学院临床医学专业本科生获学士学位 1984.09-1987.06武汉大学第一临床学院神经病学硕士研究生获硕士学位 2002.09-2006.06武汉大学第一临床学院内科学博士研究生获博士学位
工作履历	1987.07-1992.9武汉大学人民医院神经内科住院医师 1992.10-1997.09武汉大学人民医院神经内科主治医师 1997.10-2002.09武汉大学人民医院神经内科副教授，副主任医师 2002.10-至今武汉大学人民医院神经内科主任医师 2004.05至今武汉大学人民医院神经内科副主任
成果获奖	1.《汉语失语症研究：汉语失语症标准化检查法及CT图像标准化研究》1992年获卫生部科技进步二等奖 2.《90例中国人利手与优势半球研究》1992年卫生部全国中青年优秀论文三等奖 3.《神经肌肉疾病的地区差异探讨及精准化诊疗》2019年湖北省科技进步二等奖
代表性论著	1.Fang C, Lv L, Mao S, Dong H, Liu B.Cognition Deficits in Parkinson's Disease: Mechanisms and Treatment. Parkinson's disease, 2020. 2020: p. 2076942. 2.Lv, L; Mao, S; Dong, H; Hu, P; Dong, R, Ruochen.Pathogenesis, Assessments, and Management of Chemotherapy-Related Cognitive Impairment (CRCI): An Updated Literature Review. Journal of oncology, 2020. 2020: p. 3942439. 3.Dong H, Sun Q, Zhang Y, Li Y, Yuan F, Mao S, Liu B. Genetic deletion of Rnd3 suppresses apoptosis through NF-κB signaling in the brain.Oncology reports. 2020,45(2):595-605. 4.Wang S, Mao S, Yao B, Xiang D, Fang C.Effects of low-frequency repetitive transcranial magnetic stimulation on depression- and anxiety-like behaviors in epileptic rats. Journal of Integrative Neuroscience, 2019, 18(3): 237-243. 5.Cai Q, Guo Q, Zhang F, Sun D, Zhang W, Ji B, et al. Evacuation of chronic and subacute subdural hematoma via transcranial neuroendoscopic approach. Neuropsychiatric disease and treatment, 2019. 15: p. 385-390. 5. 6Wang S, Mao S, Xiang D, Fang C.Association between depression and the subsequent risk of Parkinson's disease: A meta-analysis. Progress in Neuropsychopharmacology & Biological Psychiatry. 2018, 86:186–192 7. Dong H, Lin X, Li Y, Hu R, Xu Y, Guo X, et al.Genetic deletion of RND3 in neural stem cells promotes proliferation via upregulation of Notch signaling. Oncotarget 2017,8(53)：91112-91122. 8. Fang C, Gu L, Smerin D, Mao S, Xiong X.The interrelation between Reactive Oxygen Species (ROS) and Autophagy in Neurological Disorders. Oxidative Medicine and Cellular Longevity. 2017 (3) :1-16 9. Liu B, Dong H, Lin X, Yang X, Yue X, Yang J, et al.RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion. Oncotarget, 2016, 7 (50): 82411-82423. 10.Mao S, Xiong G, Zhang L, Dong H, Liu B, Cohen NA, et al. Verification of the Cross Immunoreactivity of A60, a Mouse Monoclonal Antibody against Neuronal Nuclear Protein. Frontiers in neuroanatomy 2016, 54(10):1-11 11.Liu B, Lin X, Yang X, Dong H, Yue X, Andrade KC, et al. Downregulation of RND 3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity. Cancer Medicine.2015,4(9):1404-1416 12.Dong H, Mao S, Mao S, Wei J, Liu B, Zhang Z, et al. Tanshinone IIA protects PC12 cells from β-amyloid25–35-induced apoptosis via PI3K/Akt signaling pathway. Molecular Biology reports 2012,(39):6495–6503 13.Yan M, Mao S, Dong H, Liu B, Zhang Q, Pan G, et al. Schisandrin B protects PC12 cells by decreasing the expression of amyloid-beta precursor protein and vacuolar protein sorting 35. Neural Regeneration Research 2012,7(9):652-658 14.Niu, J; Xiong, J; Hu, D; Zeng, F; Nie, S; Mao, S; Wang, T; Zhang, Z; Zhang, Z.2',3'-Dideoxycytidine Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease. Neurochemical research, 2017. 42(10): p. 2996-3004. 15.杨继颖;毛善平.静息态功能磁共振成像在缺血性脑卒中运动性失语症中的应用价值分析[J].中国医学前沿杂志(电子版),2020,12(03):78-82. 16.董慧敏;刘宝辉;孙前;吕龙琴;毛善平.RND1通过p53蛋白促进PC12细胞凋亡[J].卒中与神经疾病,2019,26(06):649-652+663. 17.董慧敏;袁凡恩;方聪聪;刘宝辉;毛善平.Rnd3在中枢神经系统对IL-8的调控作用及其机制[J].武汉大学学报(医学版),2019,40(03):345-349.18.黄年平,毛善平,孙进.芳香开窍药嗅吸对急性脑梗死昏迷患者促醒作用的研究[J].现代中西医结合杂志,2018,27(34):3794-3798.19.方聪聪,毛善平,曾智,董慧敏,刘宝辉,王舜,谭华威.大鼠早期局灶性脑缺血再灌注损伤中USP10的表达水平变化及其与自噬的关系[J].卒中与神经病,2017,24(04):290-296.20.王安平,毛善平.急性小脑出血患者失眠与出血部位、神经损伤程度和IL-1β浓度的关系[J].海南医学,2017,28(16):2604-2608.

Name	SHANPING MAO
Date of birth	October，1964
Department	Neurology Department，Renmin Hospitalof Wuhan University.
Title	Chief physician，Professor，deputy director，master tutor
Email	maospzy@163.com
TEL	027-88041911-82221or 18602716397
Research Direction	1. cognitive disorder：the diagnosis and treatment of aphsia，memory disorders，dementia and elderly nervous system disease 2.Parkinson's disease and dyskinesia diseases
Personal Profile	Dr. Shanping Mao is currently a professor, Chief physician of Neurology department at the Renmin Hospital of Wuhan University, deputy director of Neurology Department, and expert in diagnosis and treatment of cerebrovascular disease, aphasia, memory disorders, dementia and elderly nervous system disease. He has been awarded 1 items for the National Natural Science Foundation, and has take part in more than ten provincial projects as the host or project member. Dr. Shanping Mao is neurology branch of Chinese medical association neuropsychology and behavioral neurology study group members, the Chinese medical doctor association of sleep medicine experts committee, China society of stroke rehabilitation of stroke branch committee member, China geriatrics society cognitive branch committee, member of Chinese society for the study of sleep sleep disorders, elderly cognitive psychology branch of China elderly care medical association member, China council for the promotion of rehabilitation technology speech rehabilitation professional committee, the Chinese society of gerontology and geriatric medicine cognition and brain health club members, China geriatrics society cognitive branch neuropsychological scale assessment committee. He is also a reviewer of the Editorial Board of the Chinese Journal of Neurology, a member of the Editorial Board of the English edition of Neural Regeneration Research in China, the deputy editor of Stroke and Nervous Diseases and the reviewer of Medical Journal of Wuhan University. Dr. Mao has received second prize award of Progresses of Science and Technology of the Ministry of Health , third prize of Excellent Paper Award of Ministry of Health and second prize award of Progresses of Science and Technology of Hubei Province. By now, he has educated 39 masters. At present, there are 3 Masters studying with him.
Selected Publications	1.Fang C, Lv L, Mao S, Dong H, Liu B.Cognition Deficits in Parkinson's Disease: Mechanisms and Treatment. Parkinson's disease, 2020. 2020: p. 2076942. 2.Lv, L; Mao, S; Dong, H; Hu, P; Dong, R, Ruochen.Pathogenesis, Assessments, and Management of Chemotherapy-Related Cognitive Impairment (CRCI): An Updated Literature Review. Journal of oncology, 2020. 2020: p. 3942439. 3.Dong H, Sun Q, Zhang Y, Li Y, Yuan F, Mao S, Liu B. Genetic deletion of Rnd3 suppresses apoptosis through NF-κB signaling in the brain.Oncology reports. 2020,45(2):595-605. 4.Wang S, Mao S, Yao B, Xiang D, Fang C.Effects of low-frequency repetitive transcranial magnetic stimulation on depression- and anxiety-like behaviors in epileptic rats. Journal of Integrative Neuroscience, 2019, 18(3): 237-243. 5.Cai Q, Guo Q, Zhang F, Sun D, Zhang W, Ji B, et al. Evacuation of chronic and subacute subdural hematoma via transcranial neuroendoscopic approach. Neuropsychiatric disease and treatment, 2019. 15: p. 385-390. 5. 6Wang S, Mao S, Xiang D, Fang C.Association between depression and the subsequent risk of Parkinson's disease: A meta-analysis. Progress in Neuropsychopharmacology & Biological Psychiatry. 2018, 86:186–192 7. Dong H, Lin X, Li Y, Hu R, Xu Y, Guo X, et al.Genetic deletion of RND3 in neural stem cells promotes proliferation via upregulation of Notch signaling. Oncotarget 2017,8(53)：91112-91122. 8. Fang C, Gu L, Smerin D, Mao S, Xiong X.The interrelation between Reactive Oxygen Species (ROS) and Autophagy in Neurological Disorders. Oxidative Medicine and Cellular Longevity. 2017 (3) :1-16 9. Liu B, Dong H, Lin X, Yang X, Yue X, Yang J, et al.RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion. Oncotarget, 2016, 7 (50): 82411-82423. 10.Mao S, Xiong G, Zhang L, Dong H, Liu B, Cohen NA, et al. Verification of the Cross Immunoreactivity of A60, a Mouse Monoclonal Antibody against Neuronal Nuclear Protein. Frontiers in neuroanatomy 2016, 54(10):1-11 11.Liu B, Lin X, Yang X, Dong H, Yue X, Andrade KC, et al. Downregulation of RND 3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity. Cancer Medicine.2015,4(9):1404-1416 12.Dong H, Mao S, Mao S, Wei J, Liu B, Zhang Z, et al. Tanshinone IIA protects PC12 cells from β-amyloid25–35-induced apoptosis via PI3K/Akt signaling pathway. Molecular Biology reports 2012,(39):6495–6503 13.Yan M, Mao S, Dong H, Liu B, Zhang Q, Pan G, et al. Schisandrin B protects PC12 cells by decreasing the expression of amyloid-beta precursor protein and vacuolar protein sorting 35. Neural Regeneration Research 2012,7(9):652-658 14.Niu, J; Xiong, J; Hu, D; Zeng, F; Nie, S; Mao, S; Wang, T; Zhang, Z; Zhang, Z.2',3'-Dideoxycytidine Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease. Neurochemical research, 2017. 42(10): p. 2996-3004.