武汉大学人民医院湖北省人民医院

院内导航

谢青贞 妇产科
科主任，教授，二级主任医师，博士生导师

A+ A-

导师介绍

姓名	谢青贞
出生年月	1968年2月
单位	武汉大学人民医院生殖医学中心
所属学科	临床医学-妇产科学
职务、职称及头衔	科主任，教授，二级主任医师，博士生导师
E-mail	qingzhenxie@hotmail.com
联系方式	13296500268
研究方向	1. 不孕症及辅助生殖技术 2. 生殖内分泌疾病
个人简介	主要从事不孕症的诊疗和辅助生殖技术，以及生殖内分泌疾病。主持国家自然科学基金面上项目2项，主持湖北省重点研发项目及省级课题6项，主编和副主编专著各1部，以第一作者或通讯作者发表论文40余篇，其中SCI论文收录12篇，SCI二区论文5篇。已培研究生18名，目前正在培养的硕士研究生5名。
学术任职与荣誉	中国妇幼保健协会生育保健专业委员会委员中国优生优育协会助孕与优生专业委员会常委湖北省医学会生殖医学分会第四届委员会副主任委员湖北省免疫学会生殖免疫专业委员会副主任委员国家自然科学基金项目评审专家《武汉大学学报医学版）》编委武汉大学人民医院2022年医疗名家
教育履历	1986.09-1991.06武汉大学医学院临床医学本科生获学士学位 1994.09-1997.06武汉大学医学院妇产科硕士研究生获硕士学位 2000.09-2003.06华中科技大学附属同济医学院妇产科博士研究生获博士学位
工作履历	1991.06-1994.08武汉大学人民医院妇产科 1997.07-2000.8武汉大学人民医院妇产科 2003.7-至今武汉大学人民医院生殖医学中心
成果获奖	1.获得国家级、湖北省和武汉市科技进步奖4项 2.连续5年获武汉大学人民医院核心人才奖
代表性论著	1. Chen, Liang et al. “Cycle Characteristics and Pregnancy Outcomes of Early Rescue Intracytoplasmic Sperm Injection Cycles in Normal and Hyper-Ovarian Response Women: A Six-Year Retrospective Study.” Journal of clinical medicine vol. 12,5 1993. 2 Mar. 2023, doi:10.3390/jcm12051993 2. Liu Q, Ding J, Xie Q. Regulatory Effects of Fyn on Trophoblast Cell Behaviors and Function. Biomed Res Int. 2022;2022:6006981. Published 2022 Oct 25. doi:10.1155/2022/6006981 3.Luo J, Qi Q, Chen Y, et al. Effect of GnRH-antagonist, mifepristone and letrozole on preventing ovarian hyperstimulation syndrome in rat model,Reprod Biomed Online,2021,42(2):291-300. 4.Qi Q, Luo J, Wang Y, et al. Effects of artificial cycles with and without gonadotropin-releasing hormone agonist pretreatment on frozen embryo transfer outcomes,Journal of International Medical Research,2020,48(6):1410561991. 5.Qi Q, Yang Y, Wu K, et al. Inhibition of TMEM16A impedes embryo implantation and decidualization in mice,Reproduction,2018,156(6):569-577. 6.Wang X, Qi Q, Wu K, et al. Role of Osteopontin in decidualization and pregnancy success, Reproduction, 2018, 155(5):REP-17-0782. 7.Chen Y M, Qian-Rong Q I，Xie Q Z, et al. Effect of progestin-primed ovarian stimulation protocol on outcomes of aged infertile women who failed to get pregnant in the first ivf/icsi cycle:a self-controlled study, J Huazhong Univ Sci Technolog Med Sci, 2018, 38(3):513-518. 8.H Zhou, WM Xu, QR Qi, QZ Xie. Osteopontin regulates trophoblast proliferation and invasion and associates with spontaneous abortion, Int J Clin Exp Pathol, 2016, 9(5):5230-5239. 9.Xie Q Z, Wang-Ming X U, Qian-Rong Q I, et al. Patients with Cervical Ureaplasma Urealyticum and Chlamydia Trachomatis Infection Undergoing IVF/ICSI-ET: The Need for New Paradigm，J Huazhong Univ Sci Technolog Med Sci, 2016, 36(5):716-722. 10.Wu L Z, Liu X L, Xie Q Z. Osteopontin facilitates invasion in human trophoblastic cells via promoting matrix metalloproteinase-9 in vitro, Int J Clin Exp Pathol, 2015, 8 (11) :14121. 11.Qian L, Qing-Zhen X, Yun Z, et al. Osteopontin is expressed in the oviduct and promotes fertilization and preimplantation embryo development of mouse, Zygote, 2015, 23(4):622-630. 12.Wang J, Wu F, Xie Q, et al. Anakinra and etanercept prevent embryo loss in pregnant nonobese diabetic mice, Reproduction, 2015, 149(4):377-384. 13.Qi Q R, Xie Q Z, Liu X L, et al. Osteopontin Is Expressed in the Mouse Uterus during Early Pregnancy and Promotes Mouse Blastocyst Attachment and Invasion In Vitro, Plos One, 2014, 9(8):e104955. 14.Xie Q Z, Qi Q R, Chen Y X, et al. Uterine Micro-Environment and Estrogen-Dependent Regulation of Osteopontin Expression in Mouse Blastocyst, International Journal of Molecular Sciences, 2013, 14(7):14504-14517

Name	XIE QING ZHEN
Date of birth	February,1968
Department	Reproductive Medicine Center, Renmin Hospital, Wuhan University
Title	Director, Professor, doctoral tutor
Email	qingzhenxie@hotmail.com
TEL	13296500268
Research Direction	1.Infertility and assisted reproductive technology 2. Reproductive endocrine disorders
Personal Profile	She is mainly engaged in diagnosis and treatment of infertility and assisted reproductive technology, as well as reproductive endocrine disorders. She has been awared 2 projects of the National Natural Science Foundation of China, 6 items of the provincial and ministerial key scientific research programs.She has published more than 40 papers as the first author or corresponding author, including 12 SCI papers and 5 of which published in the second district of SCI. 18 postgraduates have been trained and 5 postgraduates are currently under training.
Selected Publications	1. Chen, Liang et al. “Cycle Characteristics and Pregnancy Outcomes of Early Rescue Intracytoplasmic Sperm Injection Cycles in Normal and Hyper-Ovarian Response Women: A Six-Year Retrospective Study.” Journal of clinical medicine vol. 12,5 1993. 2 Mar. 2023, doi:10.3390/jcm12051993 2. Liu Q, Ding J, Xie Q. Regulatory Effects of Fyn on Trophoblast Cell Behaviors and Function. Biomed Res Int. 2022;2022:6006981. Published 2022 Oct 25. doi:10.1155/2022/6006981 3.Luo J, Qi Q, Chen Y, et al. Effect of GnRH-antagonist, mifepristone and letrozole on preventing ovarian hyperstimulation syndrome in rat model,Reprod Biomed Online,2021,42(2):291-300. 4.Qi Q, Luo J, Wang Y, et al. Effects of artificial cycles with and without gonadotropin-releasing hormone agonist pretreatment on frozen embryo transfer outcomes,Journal of International Medical Research,2020,48(6):1410561991. 5.Qi Q, Yang Y, Wu K, et al. Inhibition of TMEM16A impedes embryo implantation and decidualization in mice,Reproduction,2018,156(6):569-577. 6.Wang X, Qi Q, Wu K, et al. Role of Osteopontin in decidualization and pregnancy success, Reproduction, 2018, 155(5):REP-17-0782. 7.Chen Y M, Qian-Rong Q I，Xie Q Z, et al. Effect of progestin-primed ovarian stimulation protocol on outcomes of aged infertile women who failed to get pregnant in the first ivf/icsi cycle:a self-controlled study, J Huazhong Univ Sci Technolog Med Sci, 2018, 38(3):513-518. 8.H Zhou, WM Xu, QR Qi, QZ Xie. Osteopontin regulates trophoblast proliferation and invasion and associates with spontaneous abortion, Int J Clin Exp Pathol, 2016, 9(5):5230-5239. 9.Xie Q Z, Wang-Ming X U, Qian-Rong Q I, et al. Patients with Cervical Ureaplasma Urealyticum and Chlamydia Trachomatis Infection Undergoing IVF/ICSI-ET: The Need for New Paradigm，J Huazhong Univ Sci Technolog Med Sci, 2016, 36(5):716-722. 10.Wu L Z, Liu X L, Xie Q Z. Osteopontin facilitates invasion in human trophoblastic cells via promoting matrix metalloproteinase-9 in vitro, Int J Clin Exp Pathol, 2015, 8 (11) :14121. 11.Qian L, Qing-Zhen X, Yun Z, et al. Osteopontin is expressed in the oviduct and promotes fertilization and preimplantation embryo development of mouse, Zygote, 2015, 23(4):622-630. 12.Wang J, Wu F, Xie Q, et al. Anakinra and etanercept prevent embryo loss in pregnant nonobese diabetic mice, Reproduction, 2015, 149(4):377-384. 13.Qi Q R, Xie Q Z, Liu X L, et al. Osteopontin Is Expressed in the Mouse Uterus during Early Pregnancy and Promotes Mouse Blastocyst Attachment and Invasion In Vitro, Plos One, 2014, 9(8):e104955. 14.Xie Q Z, Qi Q R, Chen Y X, et al. Uterine Micro-Environment and Estrogen-Dependent Regulation of Osteopontin Expression in Mouse Blastocyst, International Journal of Molecular Sciences, 2013, 14(7):1450414517.