武汉大学人民医院湖北省人民医院

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黄鹤心内
心内科副主任、房颤中心主任，教授，博士生导师

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导师介绍

姓名	黄鹤
出生年月	1977年10月
单位	武汉大学人民医院心血管内科
所属学科	临床医学-内科学
职务、职称及头衔	心内科副主任、房颤中心主任，教授，博士生导师
E-mail	huanghe1977@whu.edu.cn
联系方式	027-88041911-81038
研究方向	1.心律失常机制研究及临床诊疗 2.心电生物基础研究
个人简介	主要从事心血管疾病的诊治与科研工作，先后主持了6项国家级课题，其中国家重点研发计划1项，国家自然科学基金面上项目4项，国家自然科学基金青年项目1项，主持1项教育部新世纪优秀人才计划及2项省级课题，湖北省科技支撑计划项目1项，湖北省自然科学基金计划重点项目1项。以第一作者或通讯作者共发表学术论文60余篇，其中SCI50篇，包括JAMA Cardiology、European Heart Journal、JACC-CI、Cardiovascular research、Europace等心血管领域权威期刊，参与主编、参编专著3部。参与国际及国家指南制定多项。获国家科技进步奖二等奖1项，华夏医学科技奖一等奖1项，湖北省科技进步奖一等奖2项，湖北省科技成果推广奖一等奖1项，湖北省科技进步奖二等奖1项，第十届湖北省青年科技奖，被评为第一届武汉市中青年医学骨干人才和湖北省优秀青年骨干人才。已培养硕士生16名，博士生25名。目前正在培养的博士生5名，硕士生3名。
学术任职与荣誉	美国心脏病学会会员（FACC）；欧洲心脏病学会会员（FESC）；欧洲心律学会会员（FEHRA）；亚太心律学会会员（APHRS)；美国心律学会会员（FHRS)；中华医学会心电生理和起搏分会（CSPE）第八届委员会常务委员，左心耳封堵工作委员会主任委员；中国医师协会心律学专业委员会（CSA）第三届委员会常务委员兼总干事；CSPE及CSA中青年电生理工作委员会联合主任委员；中国医促会心律与心电心律与心电分会副主任委员；国家卫生计生委脑卒中防治专家委员会房颤卒中防治专业委员会常务委员；湖北省心律失常防治中心主任委员；湖北省医师学会心律学分会委员会主任委员；湖北省医学会心电生理与起搏分会第五届委员会副主任委员；房颤中心联盟副主席，左心耳封堵工作委员会联合主任委员；全国心血管疾病介入诊疗技术培训项目培训基地导师
教育履历	1996.09 - 2001.06武汉大学第一临床学院临床医学专业本科生获学士学位 2002.02 - 2006.06德国鲁尔波鸿大学博士研究生获医学博士学位
工作履历	2004.07 - 2008.11武汉大学人民医院心血管内科住院医师 2008.12 - 2012.11武汉大学人民医院心血管内科副教授 2012.12 -至今武汉大学人民医院心血管内科教授
成果获奖	1.《左心耳封堵预防心房颤动患者血栓栓塞事件的基础与临床》获湖北省科技进步二等奖 2.《心律失常的结构和神经重构的基础研究和临床防治》获国家科学技术成果进步二等奖 3.《快速性心律失常的基础与临床研究》获华夏医学科技奖一等奖 4.《心房颤动的防治策略研究与推广应用》获湖北省科技成果推广奖一等奖 5.《心肌重构的发病基础与临床防治》获湖北省科技成果推广奖一等奖
代表性论著	1. Liu Q, Zhu J, Kong B, Shuai W, Huang H. Tirzepatide attenuates lipopolysaccharide-induced left ventricular remodeling and dysfunction by inhibiting the TLR4/NF-kB/NLRP3 pathway. Int Immunopharmacol. 2023;120:110311. (Corresponding Author) 2. Zhou MM, Li DW, Xu L, Kong B, Wang X, Tang YH, Huang H, Liu Y. Propionate alleviated post-infarction cardiac dysfunction by macrophage polarization in a rat model. Int Immunopharmacol. 2023;115:109618.(Corresponding Author) 3. Gong Y, Kong B, Shuai W, Chen T, Zhang J, Huang H. Effect of sotagliflozin on ventricular arrhythmias in mice with myocardial infraction. Eur J Pharmacol. 2022;936:175357. (Corresponding Author) 4. Kong B, Fu H, Xiao Z, Zhou Y, Shuai W, Huang H. Gut Microbiota Dysbiosis Induced by a High-Fat Diet Increases Susceptibility to Atrial Fibrillation. Can J Cardiol. 2022;38(12):1962-1975.(Corresponding Author) 5. Shi S, Tang Y, Zhao Q, Yan H, Yu B, Zheng Q, Li Y, Zheng L, Yuan Y, Zhong J, Xu J, Wu Y, Xu J, Chen L, Li S, Jiang J, Wang J, Fan J, Chen M, Tang B, Li W, Wu Q, Shi B, Zhou S, Zhao X, Yin Y, Zhang Z, Zhong G, Han X, Liu F, Wu M, Gao L, Yang B, Huang H, Huang C; China Atrial Fibrillation Center Project Team). Prevalence and risk of atrial fibrillation in China: A national cross-sectional epidemiological study. Lancet Reg Health West Pac. 2022;23:100439. (Corresponding Author) 6. Yang HJ, Kong B, Shuai W, Zhang JJ, Huang H. Shensong Yangxin attenuates metabolic syndrome-induced atrial fibrillation via inhibition of ferroportin-mediated intracellular iron overload. Phytomedicine. 2022;101:154086. (Corresponding Author) 7. Zhou M, Li D, Xie K, Xu L, Kong B, Wang X, Tang Y, Liu Y, Huang H. The short-chain fatty acid propionate improved ventricular electrical remodeling in a rat model with myocardial infarction. Food Funct. 2021;12(24):12580-12593. (Corresponding Author) 8. Fang J, Kong B, Shuai W, Xiao Z, Dai C, Qin T, Gong Y, Zhu J, Liu Q, Huang H. Ferroportin-mediated ferroptosis involved in new-onset atrial fibrillation with LPS-induced endotoxemia. Eur J Pharmacol. 2021;913:174622. (Corresponding Author) 9.Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, Gong W, Liu X, Liang J, Zhao Q, Huang H, Yang B, Huang C. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5(7):802-810. (Corresponding Author) 10.Shi S, Qin M, Cai Y, Liu T, Shen B, Yang F, Cao S, Liu X, Xiang Y, Zhao Q, Huang H, Yang B, Huang C. Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019. Eur Heart J. 2020;41(22):2070-2079. (Corresponding Author) 11.Wang G, Kong B, Shuai W, Fu H, Jiang X, Huang H. 3,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice. J Nutr Biochem. 2020;78:108341. (Corresponding Author) 12.Xiao Z, Kong B, Yang H, Dai C, Fang J, Qin T, Huang H. Key Player in Cardiac Hypertrophy, Emphasizing the Role of Toll-Like Receptor 4. Front Cardiovasc Med. 2020;7:579036. (Corresponding Author) 13.Shuai W, Kong B, Yang H, Fu H, Huang H. Loss of myeloid differentiation protein 1 promotes atrial fibrillation in heart failure with preserved ejection fraction. ESC Heart Fail. 2020;7(2):626-638. (Corresponding Author) 14.Yang HJ, Kong B, Shuai W, Zhang JJ, Huang H. Shensong Yangxin Protects Against Metabolic Syndrome-Induced Ventricular Arrhythmias by Inhibiting Electrical Remodeling. Front Pharmacol. 2020;11:993. (Corresponding Author) 15.Yang HJ, Kong B, Shuai W, Zhang JJ, Huang H. MD1 deletion exaggerates cardiomyocyte autophagy induced by heart failure with preserved ejection fraction through ROS/MAPK signalling pathway. J Cell Mol Med. 2020;24(16):9300-9312. (Corresponding Author) 16.Wang G, Kong B, Liu Y, Huang H. Percutaneous retrieval of a dislocated LAmbre left atrial appendage occluder in a canine model. J Cardiovasc Electrophysiol. 2020;31(2):529-535. (Corresponding Author) 17.Shuai W, Kong B, Fu H, Shen C, Jiang X, Huang H. MD1 Deficiency Promotes Inflammatory Atrial Remodelling Induced by High-Fat Diets. Can J Cardiol. 2019;35(2):208-216. (Corresponding Author) 18.Shen CJ, Kong B, Shuai W, Liu Y, Wang GJ, Xu M, Zhao JJ, Fang J, Fu H, Jiang XB, Huang H. Myeloid differentiation protein 1 protected myocardial function against high-fat stimulation induced pathological remodelling. J Cell Mol Med. 2019;23(8):5303-5316. (Corresponding Author) 19.Jiang X, Kong B, Shuai W, Shen C, Yang F, Fu H, Huang H. Loss of MD1 exacerbates myocardial ischemia/reperfusion injury and susceptibility to ventricular arrhythmia. Eur J Pharmacol. 2019;844:79-86. (Corresponding Author) 20.Shuai W, Kong B, Fu H, Shen C, Huang H. Loss of MD1 increases vulnerability to ventricular arrhythmia in diet-induced obesity mice via enhanced activation of the TLR4/MyD88/CaMKII signaling pathway. Nutr Metab Cardiovasc Dis. 2019;29(9):991-998. (Corresponding Author)

Name	HE HUANG
Date of birth	October，1977
Department	Cardiovascular Department，Renmin Hospital,Wuhan University.
Title	Professor and chief physician of Cardiology, Professor, Doctoral tutor
Email	huanghe1977@whu.edu.cn
TEL	027-88041911-81038
Research Direction	1. Cardiac arrhythmia mechanism research and clinical diagnosis and treatment 2. Basic research on electrophysiology
Personal Profile	He is mainly engaged in the diagnosis, treatment and basic research of cardiovascular diseases. He has presided over 6 national-level projects, including 1 national key research and development plan, 4 general projects of the National Natural Science Foundation of China, 1 youth project of the National Natural Science Foundation of China, and presided 1 ministry of Education's New Century Excellent Talents Program and 2 provincial projects, including 1 Hubei Provincial Science and Technology Support Program Project, and 1 Hubei Provincial Natural Science Foundation Program Key Project. As the first author or corresponding author, he has published more than 60 academic papers, including 50 SCI papers, including JAMA Cardiology, European Heart Journal, JACC-CI, Cardiovascular research, Europace and other authoritative journals in the cardiovascular field. Moreover, he has participated in the editor-in-chief and co-editing of 3 monographs. In addition, he has participated in the development of several international and national guidelines. And he has won 1 second prize of National Science and Technology Progress Award, 1 first prize of Huaxia Medical Science and Technology Award, 2 first prizes of Hubei Province Science and Technology Progress Award, 1 first prize of Hubei Province Science and Technology Achievement Promotion Award, 1 second Hubei Province Science and Technology Progress Award prize, and 1 Hubei Provincial Youth Science and Technology Award. Besides, he was rated as the 1st Wuhan Young and Middle-aged Medical Backbone Talents and Hubei Province Outstanding Young Backbone Talents. Until now, he has trained 16 master students and 25 doctoral students. Currently, there are 5 doctors and 3 masters studying with him.
Selected Publications	1. Liu Q, Zhu J, Kong B, Shuai W, Huang H. Tirzepatide attenuates lipopolysaccharide-induced left ventricular remodeling and dysfunction by inhibiting the TLR4/NF-kB/NLRP3 pathway. Int Immunopharmacol. 2023;120:110311. (Corresponding Author) 2. Zhou MM, Li DW, Xu L, Kong B, Wang X, Tang YH, Huang H, Liu Y. Propionate alleviated post-infarction cardiac dysfunction by macrophage polarization in a rat model. Int Immunopharmacol. 2023;115:109618.(Corresponding Author) 3. Gong Y, Kong B, Shuai W, Chen T, Zhang J, Huang H. Effect of sotagliflozin on ventricular arrhythmias in mice with myocardial infraction. Eur J Pharmacol. 2022;936:175357. (Corresponding Author) 4. Kong B, Fu H, Xiao Z, Zhou Y, Shuai W, Huang H. Gut Microbiota Dysbiosis Induced by a High-Fat Diet Increases Susceptibility to Atrial Fibrillation. Can J Cardiol. 2022;38(12):1962-1975.(Corresponding Author) 5. Shi S, Tang Y, Zhao Q, Yan H, Yu B, Zheng Q, Li Y, Zheng L, Yuan Y, Zhong J, Xu J, Wu Y, Xu J, Chen L, Li S, Jiang J, Wang J, Fan J, Chen M, Tang B, Li W, Wu Q, Shi B, Zhou S, Zhao X, Yin Y, Zhang Z, Zhong G, Han X, Liu F, Wu M, Gao L, Yang B, Huang H, Huang C; China Atrial Fibrillation Center Project Team). Prevalence and risk of atrial fibrillation in China: A national cross-sectional epidemiological study. Lancet Reg Health West Pac. 2022;23:100439. (Corresponding Author) 6. Yang HJ, Kong B, Shuai W, Zhang JJ, Huang H. Shensong Yangxin attenuates metabolic syndrome-induced atrial fibrillation via inhibition of ferroportin-mediated intracellular iron overload. Phytomedicine. 2022;101:154086. (Corresponding Author) 7. Zhou M, Li D, Xie K, Xu L, Kong B, Wang X, Tang Y, Liu Y, Huang H. The short-chain fatty acid propionate improved ventricular electrical remodeling in a rat model with myocardial infarction. Food Funct. 2021;12(24):12580-12593. (Corresponding Author) 8. Fang J, Kong B, Shuai W, Xiao Z, Dai C, Qin T, Gong Y, Zhu J, Liu Q, Huang H. Ferroportin-mediated ferroptosis involved in new-onset atrial fibrillation with LPS-induced endotoxemia. Eur J Pharmacol. 2021;913:174622. (Corresponding Author) 9.Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, Gong W, Liu X, Liang J, Zhao Q, Huang H, Yang B, Huang C. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5(7):802-810. (Corresponding Author) 10.Shi S, Qin M, Cai Y, Liu T, Shen B, Yang F, Cao S, Liu X, Xiang Y, Zhao Q, Huang H, Yang B, Huang C. Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019. Eur Heart J. 2020;41(22):2070-2079. (Corresponding Author) 11.Wang G, Kong B, Shuai W, Fu H, Jiang X, Huang H. 3,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice. J Nutr Biochem. 2020;78:108341. (Corresponding Author) 12.Xiao Z, Kong B, Yang H, Dai C, Fang J, Qin T, Huang H. Key Player in Cardiac Hypertrophy, Emphasizing the Role of Toll-Like Receptor 4. Front Cardiovasc Med. 2020;7:579036. (Corresponding Author) 13.Shuai W, Kong B, Yang H, Fu H, Huang H. Loss of myeloid differentiation protein 1 promotes atrial fibrillation in heart failure with preserved ejection fraction. ESC Heart Fail. 2020;7(2):626-638. (Corresponding Author) 14.Yang HJ, Kong B, Shuai W, Zhang JJ, Huang H. Shensong Yangxin Protects Against Metabolic Syndrome-Induced Ventricular Arrhythmias by Inhibiting Electrical Remodeling. Front Pharmacol. 2020;11:993. (Corresponding Author) 15.Yang HJ, Kong B, Shuai W, Zhang JJ, Huang H. MD1 deletion exaggerates cardiomyocyte autophagy induced by heart failure with preserved ejection fraction through ROS/MAPK signalling pathway. J Cell Mol Med. 2020;24(16):9300-9312. (Corresponding Author) 16.Wang G, Kong B, Liu Y, Huang H. Percutaneous retrieval of a dislocated LAmbre left atrial appendage occluder in a canine model. J Cardiovasc Electrophysiol. 2020;31(2):529-535. (Corresponding Author) 17.Shuai W, Kong B, Fu H, Shen C, Jiang X, Huang H. MD1 Deficiency Promotes Inflammatory Atrial Remodelling Induced by High-Fat Diets. Can J Cardiol. 2019;35(2):208-216. (Corresponding Author) 18.Shen CJ, Kong B, Shuai W, Liu Y, Wang GJ, Xu M, Zhao JJ, Fang J, Fu H, Jiang XB, Huang H. Myeloid differentiation protein 1 protected myocardial function against high-fat stimulation induced pathological remodelling. J Cell Mol Med. 2019;23(8):5303-5316. (Corresponding Author) 19.Jiang X, Kong B, Shuai W, Shen C, Yang F, Fu H, Huang H. Loss of MD1 exacerbates myocardial ischemia/reperfusion injury and susceptibility to ventricular arrhythmia. Eur J Pharmacol. 2019;844:79-86. (Corresponding Author) 20.Shuai W, Kong B, Fu H, Shen C, Huang H. Loss of MD1 increases vulnerability to ventricular arrhythmia in diet-induced obesity mice via enhanced activation of the TLR4/MyD88/CaMKII signaling pathway. Nutr Metab Cardiovasc Dis. 2019;29(9):991-998. (Corresponding Author)