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  • 杨嗣星 泌尿外科学
    科主任,教授,主任医师,博士生导师
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    导师介绍

    姓名 杨嗣星
    出生年月 1962年5月
    单位 武汉大学人民医院泌外2科
    所属学科 临床医学-外科学
    职务、职称及头衔 科主任,教授,主任医师,博士生导师
    E-mail sxyang2004@163.com,sxyang@whu.edu.cn
    联系方式 027-88041911转81108或13607112397
    研究方向 1.肾结石防治
    2.泌尿外科组织工程技术
    个人简介 主要从事泌尿系疾病的诊治与科研工作,获国家自然科学基金2项、省科技厅、省教委、省卫生厅课题多项。出版《软性输尿管镜术培训教程》和《软性输尿管镜标准化教程》两部专著,在《临床泌尿外科杂志》、《中华泌尿外科杂志》杂志上发表论文100余篇,以第一作者发表论文50余篇,其中SCI论文近20篇,影响因子超过50。已培养硕士生20名,博士生8名。目前正在培养的博士生2名,硕士生6名。
    学术任职与荣誉 中华医学会泌尿外科分会结石学组委员
    中国尿结石联盟副主席,国际尿结石联盟理事
    中国地质学会医学地质专业委员会副主任委员
    中国卫企管理协会转化医学分会尿路结石防治专委会主任委员
    中国医药教育协会泌尿外科专业委员会常委
    湖北省政府中青年特殊津贴专家
    中华泌尿外科杂志常务编委
    临床泌尿外科杂志等7家杂志编委
    教育履历 2000/09-2003/06,武汉大学,第一临床学院外科学,博士
    1989/09-1992/06,湖北医科大学,第一临床学院外科学,硕士
    1981/09-1985/06,同济医科大学,医学系,本科 
    工作履历 2003/01-至今,武汉大学人民医院,泌尿外科,教授,博导
    1998/01-2002/12,武汉大学人民医院,泌尿外科,副教授,硕导
    1993/07-1997/12,武汉大学人民医院,泌尿外科,主治医师
    1985/08-1989/08,孝感市中心医院,外科,医师
    成果获奖 1.《镰刀状肾实质切开术治疗复杂鹿角状肾结石的实验和临床研究》获2004年度湖北省政府科技进步二等奖
    2.中华医学会泌尿外科分会2017年度钻石奖
    3.《软性输尿管镜术标准建立及技术创新》获2020年度湖北省政府科技进步二等奖
    4.获得2020年吴阶平泌尿外科医学奖
    代表性论著 [1] Song Q, Liao W, He Z, Li D, Dong C, Song C, Yang S. Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones. Arch Biochem Biophys. 2022 Sep 30;727:109325. doi: 10.1016/j.abb.2022.109325. Epub 2022 Jun 21. PMID: 35749806.
    [2]  Song Q, Liao W, Chen X, He Z, Li D, Li B, et al.Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones. Oxidative medicine and cellular longevity, 2021: 6630343.
    [3]  Yu G, Bai Z, Song C, Cheng Q, Wang G, Tang Z, et al.Current progress on the effect of mobile phone radiation on sperm quality: An updated systematic review and meta-analysis of human and animal studies. Environmental pollution,2021, 282: 116952.
    [4]  Song Q, He Z, Li B, Liu J, Liu L, Liao W, Xiong Y, Song C, Yang S, Liu Y. Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway. Cell Cycle. 2020 Oct;19(20):2600-2610. doi: 10.1080/15384101.2020.1810401. Epub 2020 Aug 23.
    [5] He Z, Liao W, Song Q, Li B, Liu J, Xiong Y, Song C, Yang S. Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis. Int J Mol Med. 2021 Jan;47(1):289-301. doi: 10.3892/ijmm.2020.4770. Epub 2020 Oct 23. PMID: 33416117; PMCID: PMC7723503.
    [6] Song C, Xiong Y, Liao W, Meng L, Yang S. Long noncoding RNA ATB participates in the development of renal cell carcinoma by downregulating p53 via binding to DNMT1. J Cell Physiol. 2019;234(8):12910-12917. doi:10.1002/jcp.27957
    [7] Yang SX, Song C, Xiong YH. Current perspectives on urolithiasis management in China [published online ahead of print, 2019 Nov 23]. World J Urol. 2019;10.1007/s00345-019-03026-9. doi:10.1007/s00345-019-03026-9
    [8] Liao W, Xiong Y, Yang S, et al. Efficacy and functional outcome of flexible ureteroscopy for renal stones in patients with a solitary kidney[J]. Surgical Practice,2016,20(1):13-17.
    [9] Xiong Y, Yang S, Liao W, et al. Autonomic dysreflexia during cystolitholapaxy in patients with spinal cord injury.[J]. Minerva urologica e nefrologica= The Italian journal of urology and nephrology,2015,67(2):85-90.
    [10] Xiong Y, Liao W, Yang S, et al. A tissue-engineered conduit for urinary persion using bone marrow mesenchymal stem cells and bladder acellular matrix[J]. Tissue Engineering and Regenerative Medicine,2015,12(3):188-194.
    [11] Meng L, Liao W, Yang S, et al. Seeding Homologous Adipose-Derived Stem Cells and Bladder Smooth Muscle Cells Into Bladder Submucosa Matrix for Reconstructing the Ureter in a Rabbit Model[J]. Transplantation proceedings,2015,47(10):3002-3011.
    [12] Meng L, Liao W, Yang S, et al. Tissue-engineered tubular substitutions for urinary persion in a rabbit model[J]. Experimental Biology and Medicine,2015:1011658725.
    [13] Li C, Li Y, Yang S, et al. Expression and Characterization of Antimicrobial Peptide LL-37 in Dog Peripheral Blood Endothelial Progenitor Cells In Vitro[J]. International Journal of Peptide Research and Therapeutics,2015,21(3):279-287.
    Name SIXING YANG
    Date of birth May,1962
    Department Urology Department,Renmin Hospital,Wuhan University.
    Title Director, Professor, doctoral tutor
    Director, Professor, chief physician, doctoral supervisor
    Email sxyang2004@163.com,sxyang@whu.edu.cn
    TEL 027-88041911-81108 or 13607112397
    Research Direction 1. Prevention and treatment of kidney stones
    2. Urology tissue engineering technology
    Personal Profile He is mainly engaged in the diagnosis, treatment and scientific research of urinary tract diseases, and has won 2 projects from the National Natural Science Foundation of China, and a number of projects from the Provincial Department of Science and Technology, the Provincial Education Commission, and the Provincial Department of Health. Published two monographs, "Flexible Ureteroscopy Training Course" and "Flexible Ureteroscopy Standardization Course", and published more than 100 papers in "Journal of Clinical Urology" and "Chinese Journal of Urology" as the first author. More than 50 papers, including nearly 20 SCI papers, with an impact factor of more than 50. It has trained 20 master students and 8 doctoral students. There are currently 2 doctoral students and 6 master students under training.
    Selected Publications [1] Song Q, Liao W, He Z, Li D, Dong C, Song C, Yang S. Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones. Arch Biochem Biophys. 2022 Sep 30;727:109325. doi: 10.1016/j.abb.2022.109325. Epub 2022 Jun 21. PMID: 35749806.
    [2]  Song Q, Liao W, Chen X, He Z, Li D, Li B, et al.Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones. Oxidative medicine and cellular longevity, 2021: 6630343.
    [3]  Yu G, Bai Z, Song C, Cheng Q, Wang G, Tang Z, et al.Current progress on the effect of mobile phone radiation on sperm quality: An updated systematic review and meta-analysis of human and animal studies. Environmental pollution,2021, 282: 116952.
    [4]  Song Q, He Z, Li B, Liu J, Liu L, Liao W, Xiong Y, Song C, Yang S, Liu Y. Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway. Cell Cycle. 2020 Oct;19(20):2600-2610. doi: 10.1080/15384101.2020.1810401. Epub 2020 Aug 23.
    [5] He Z, Liao W, Song Q, Li B, Liu J, Xiong Y, Song C, Yang S. Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis. Int J Mol Med. 2021 Jan;47(1):289-301. doi: 10.3892/ijmm.2020.4770. Epub 2020 Oct 23. PMID: 33416117; PMCID: PMC7723503.
    [6] Song C, Xiong Y, Liao W, Meng L, Yang S. Long noncoding RNA ATB participates in the development of renal cell carcinoma by downregulating p53 via binding to DNMT1. J Cell Physiol. 2019;234(8):12910-12917. doi:10.1002/jcp.27957
    [7] Yang SX, Song C, Xiong YH. Current perspectives on urolithiasis management in China [published online ahead of print, 2019 Nov 23]. World J Urol. 2019;10.1007/s00345-019-03026-9. doi:10.1007/s00345-019-03026-9
    [8] Liao W, Xiong Y, Yang S, et al. Efficacy and functional outcome of flexible ureteroscopy for renal stones in patients with a solitary kidney[J]. Surgical Practice,2016,20(1):13-17.
    [9] Xiong Y, Yang S, Liao W, et al. Autonomic dysreflexia during cystolitholapaxy in patients with spinal cord injury.[J]. Minerva urologica e nefrologica= The Italian journal of urology and nephrology,2015,67(2):85-90.
    [10] Xiong Y, Liao W, Yang S, et al. A tissue-engineered conduit for urinary persion using bone marrow mesenchymal stem cells and bladder acellular matrix[J]. Tissue Engineering and Regenerative Medicine,2015,12(3):188-194.
    [11] Meng L, Liao W, Yang S, et al. Seeding Homologous Adipose-Derived Stem Cells and Bladder Smooth Muscle Cells Into Bladder Submucosa Matrix for Reconstructing the Ureter in a Rabbit Model[J]. Transplantation proceedings,2015,47(10):3002-3011.
    [12] Meng L, Liao W, Yang S, et al. Tissue-engineered tubular substitutions for urinary persion in a rabbit model[J]. Experimental Biology and Medicine,2015:1011658725.
    [13] Li C, Li Y, Yang S, et al. Expression and Characterization of Antimicrobial Peptide LL-37 in Dog Peripheral Blood Endothelial Progenitor Cells In Vitro[J]. International Journal of Peptide Research and Therapeutics,2015,21(3):279-287.