罗和生
消化
曾任武汉大学人民医院内科主任，消化内科主任；现任医院教学督导委员会主任，伦理委员会副主任，教授，主任医师，博士生导师
曾任武汉大学人民医院内科主任，消化内科主任；现任医院教学督导委员会主任，伦理委员会副主任，教授，主任医师，博士生导师
导师介绍
| 姓名 | 罗和生 |
| 出生年月 | 1951年4月 |
| 单位 | 武汉大学人民医院消化内科 |
| 所属学科 | 临床医学-内科学 |
| 职务、职称及头衔 | 曾任武汉大学人民医院内科主任，消化内科主任；现任医院教学督导委员会主任，伦理委员会副主任，教授，主任医师，博士生导师 |
| xhnk@163.com | |
| 联系方式 | 027-88041911转81235 |
| 研究方向 |
1.消化道动力的基础与临床 2.胃肠动力学 |
| 个人简介 | 从事研究的领域为消化系统疾病的基础与临床,胃肠动力学。主持国家自然科学基金项目3项。获省级奖6项,以第一作者发表论文170篇,其中SCI论文30余篇,主编专著6部.已培养博士生45名，硕士生66名；目前正在培养的博士生8名，硕士生7名。 |
| 学术任职与荣誉 | 中华消化身心联盟全国常委；中华消化身心联盟湖北省主委；湖北省医师学会法人代表；《胃肠病学和肝病学杂志》副主编，《中华消化杂志》编委，《中国实用内科杂志》编委，《中国临床医生杂志》编委，《临床内科杂志》副主编，《临床消化杂志》编委，《世界华人消化杂志》编委，卫生部有突出贡献的中青年专家、湖北省有突出贡献的中青年专家 |
| 教育履历 |
1974-1977三峡大学医学院本科 1978-1981武汉同济医学院研究生 |
| 工作履历 |
1981-至今武汉大学人民医院消化内科 1988-1990瑞士巴塞尔大学访问学者 1998-1999奥地利维也那大学高级访问学者 |
| 成果获奖 |
1.经内镜治疗胃肠道粘膜下病变的应用研究2000省科技成果推广奖3等 2. HPV与消化道恶性肿瘤相关性研究2000省自然科学奖3等 3.《现代心肺脑复苏学》2000省科技进步奖2等 4.《实用消化病学》2001省科技进步奖3等 5.人胃癌组织中多种基因的变异及相互关系的研究湖北省自然科学奖3等2003 6. VEGF、CD44V6和Ⅳ型胶原酶对恶性腹水的诊断价值及形成作用的研究湖北省自然科学奖3等2004 |
| 代表性论著 |
1.
Down-Regulation of miR-126 Is Associated with Colorectal Cancer Cells
Proliferation, Migration and Invasion by Targeting IRS-1 via the AKT and
ERK1/2 Signaling Pathways. PLoS One. 2013，29(8)：e81203 2. Actions of hydrogen sulfide and ATP-sensitive potassium channels on colonic hypermotility in a rat model of chronic stress. PLoS One. 2013;8(2):e55853. 3. The DNA methyltransferase inhibitor zebularine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo. Biochem Biophys Res Commun. 2013;430(1):250-5. 4. Ca2+/calmodulin- dependent protein kinase II mediates transforming growth factor-β-induced hepatic stellate cells proliferation but not in collagen α1(I) production. Hepatol Res. 2012;42(8):806-18. 5. Ca2+/calmodulin-dependent protein kinase II mediates platelet-derived growth factor-induced human hepatic stellate cell proliferation. Dig Dis Sci. 2012;57(4):935-42. 6. Plasma hormones facilitated the hypermotility of the colon in a chronic stress rat model. PLoS One. 2012;7(2):e31774. 7. Effects of trimebutine maleate on colonic motility through Ca2+-activated K+ channels and L-type Ca2+ channels. Arch Pharm Res. 2011;34(6):979-85. 8. Expression of C-kit messenger ribonucleic acid and C-kit protein in the gallbladders in high cholesterol diet.Dig Dis Sci,Aug 2009;54(8):1651-5. 9. Sodium butyrate induces huamn colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway.J Int Med Res,May 2009;37(3):803-11. 10. Expression and prognostic roles of esg1 in resected esophageal squamous cell carcinomas.Dig Dis Sci,2008,53(8):2039-2044. |
| Name | HESHENG LUO |
| Date of birth | April，1951 |
| Department | Gastroenterology Department，Renmin Hospital,Wuhan University. |
| Title | Director, Professor, doctoral tutor |
| xzhang@whu.edu.cn | |
| TEL | 027-88041911-86731 or 1397105…… |
| Research Direction |
1.
Basis and clinic of digestive tract motility 2. Gastrointestinal dynamics |
| Personal Profile | He is mainly engaged in basis and clinic of digestive tract motility and gastrointestinal dynamics.He undertook three projects of National Natural Science Foundation of China and received 6 provincial awards.He published 170 papers as the first author, including more than 30 SCI papers and 6 monographs. He has trained 45 doctoral students and 66 master students,besides 8 doctoral students and 7 master students were training in progress. |
| Selected Publications |
1.
Down-Regulation of miR-126 Is Associated with Colorectal Cancer Cells
Proliferation, Migration and Invasion by Targeting IRS-1 via the AKT and
ERK1/2 Signaling Pathways. PLoS One. 2013，29(8)：e81203 2. Actions of hydrogen sulfide and ATP-sensitive potassium channels on colonic hypermotility in a rat model of chronic stress. PLoS One. 2013;8(2):e55853. 3. The DNA methyltransferase inhibitor zebularine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo. Biochem Biophys Res Commun. 2013;430(1):250-5. 4. Ca2+/calmodulin- dependent protein kinase II mediates transforming growth factor-β-induced hepatic stellate cells proliferation but not in collagen α1(I) production. Hepatol Res. 2012;42(8):806-18. 5. Ca2+/calmodulin-dependent protein kinase II mediates platelet-derived growth factor-induced human hepatic stellate cell proliferation. Dig Dis Sci. 2012;57(4):935-42. 6. Plasma hormones facilitated the hypermotility of the colon in a chronic stress rat model. PLoS One. 2012;7(2):e31774. 7. Effects of trimebutine maleate on colonic motility through Ca2+-activated K+ channels and L-type Ca2+ channels. Arch Pharm Res. 2011;34(6):979-85. 8. Expression of C-kit messenger ribonucleic acid and C-kit protein in the gallbladders in high cholesterol diet.Dig Dis Sci,Aug 2009;54(8):1651-5. 9. Sodium butyrate induces huamn colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway.J Int Med Res,May 2009;37(3):803-11. 10. Expression and prognostic roles of esg1 in resected esophageal squamous cell carcinomas.Dig Dis Sci,2008,53(8):2039-2044. |
武汉大学人民医院
湖北省人民医院