王高华
精神
党委副书记、院长，教授，一级主任医师，博士生导师
党委副书记、院长，教授，一级主任医师，博士生导师
导师介绍
| 姓名 | 王高华 |
| 出生年月 | 1964 |
| 单位 | 武汉大学人民医院精神科 |
| 所属学科 | 临床医学-精神病与精神卫生学 |
| 职务、职称及头衔 | 党委副书记、院长，教授，一级主任医师，博士生导师 |
| wgh6402@whu.edu.cn | |
| 联系方式 | 027-88041911转86447 |
| 研究方向 |
1.抑郁症的病因学与防治研究 2.临床精神药理学 |
| 个人简介 |
主要从事抑郁症的诊治与科研工作，湖北省医学领军人才，武汉大学珞珈杰出学者。湖北省神经精神病研究所所长，武汉大学人民医院精神卫生中心主任医师。国家临床重点专科学科带头人。中华精神科杂志副总编辑。《中国神经精神疾病杂志》编委，《Psychiatry
Research》评审专家。八年制“精神病学”教材（人民卫生出版社）副主编、联络会诊精神病学主编。累计承担（1）国家自然科学基金9项（30300108，30971041，30971040，81271496，81201058，81401117，81571325，81871072，82071523）；（2）美国stanley基金1项；（3）十二五国家支持计划“综合医院抑郁焦虑障碍的识别与防治策略研究”；（4）十三五研究项目“精神心理疾病临床研究协同网络建设示范研究”；（5）卫生部686
重性精神病防治项目；（6）国家教育部985认知与神经信息科学平台（No.
904273458）项目；（7）湖北省重点研发计划“新冠肺炎创伤后应激障碍PTSD发病机制与智能化精准防治”项目。发表SCI论文近100多篇。已培养硕士生50名，博士生20名。目前正在培养的博士生14名，硕士生9名。 |
| 学术任职与荣誉 |
学术任职： 中国医师协会科医师分会 会长（现任） 中华医学会心身医学分会副主任委员（卸任）中国研究型医院协会精神与心理专业委员会，副主任委员（卸任） 中华医学会精神医学分会第六届副主任委员（卸任） 中华医学会精神医学分会常务委员（现任） 中国医院协会精神病医院管理分会 常务委员（现任） 国务院政府特殊津贴专家 |
| 教育履历 |
1980.09-1985.06湖北医科大学临床医学专业本科生获学士学位 1988.09-1991.06湖北医科大学精神病学与精神卫生学硕士研究生获硕士学位 2000.09-2003.06武汉大学第一临床学院内科学博士研究生获博士学位 |
| 工作履历 |
1991.07—1995.07湖北省人民医院精神病学主治医师 1995.07—2001.11湖北省人民医院精神病学副主任医师、副教授 2002.11—2013.05湖北省人民医院精神病学主任医师 2005.11—2013.05湖北省人民医院精神病学教授 2011.11—2013.05湖北省人民医院精神病学主任医师（二级岗） 1997.10—至今湖北省人民医院精神医学硕士生导师 2003.10—至今武汉大学政治与公共管理学院心理学硕士生导师 2004.06—至今湖北省人民医院精神病学博士生导师 |
| 成果获奖 |
1.湖北省人民政府，湖北省科技进步奖，弓形虫隐性感染与精神分裂症相关性的基础与临床研究.二等（第一完成人），2012年 2.湖北省人民政府，湖北省科技进步奖，家庭心理医生.二等（第一完成人），2006年 3,.粟宗华精神卫生基金会，粟宗华精神卫生奖，氯氮平及其代谢产物对大鼠胰岛细胞内钙的影响.一等（第一完成人）（专业协会最高奖），2007年 4.武汉市人民政府，武汉市科技进步奖，弓形虫隐性感染与精神分裂症相关性的基础与临床研究.二等（第一完成人），2012年 |
| 代表性论著 |
1.
Wei Y, Li J, Wang H, Wang G. NUCB2/nesfatin-1: Expression and functions in
the regulation of emotion and stress. Prog Neuropsychopharmacol Biol
Psychiatry. 2018, 81:221-227. 2. Nan C, Wang G, Wang H, Wang X, Liu Z, Xiao L, Bai H, Wu S. The P300 component decreases in a bimodal oddball task in individuals with depression: An event-related potentials study. Clin Neurophysiol. 2018, 129(12):2525-2533. 3. Bian H, Wang G, Huang J, Liang L, Zheng Y, Wei Y, Wang H, Xiao L, Wang H. Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat. J Neuroinflammation. 2020, 17(1):166. 4. Kang L, Li Y, Hu S, Chen M, Yang C, Yang BX, Wang Y, Hu J, Lai J, Ma X, Chen J, Guan L, Wang G, Ma H, Liu Z. The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus. Lancet Psychiatry. 2020, 7(3):e14. 5. Wu Z, Zhou L, Sun L, Xie Y, Xiao L, Wang H, Wang G. Brief postpartum separation from offspring promotes resilience to lipopolysaccharide challenge-induced anxiety and depressive-like behaviors and inhibits neuroinflammation in C57BL/6J dams. Brain Behav Immun. 2021, 95:190-202. 6. Bian H, Xiao L, Liang L, Xie Y, Wang H, Wang G. RGFP966 is protective against lipopolysaccharide-induced depressive-like behaviors in mice by inhibiting neuroinflammation and microglial activation. Int Immunopharmacol. 2021, 101(Pt B):108259. 7. Wei Y, Wang G, Chen J, Xiao L, Wu Z, He J, Zhang N. Maternal deprivation induces cytoskeletal alterations and depressive-like behavior in adult male rats by regulating the AKT/GSK3β/CRMP2 signaling pathway. Physiol Behav. 2021, 242:113625. 8. Xiang D, Sun S, Wang G, Liu Z. Effects of CRMP2 DNA Methylation in the Hippocampus on Depressive-Like Behaviors and Cytoskeletal Proteins in Rats. Front Cell Neurosci. 2021, 15:644663. 9. Liang L, Yu J, Xiao L, Wang G. Sustained low-dose prophylactic early erythropoietin for improvement of neurological outcomes in preterm infants:A systematic review and meta-analysis. J Affect Disord. 2021, 282:1187-1192. 10. Xie Y, Xiao L, Chen L, Zheng Y, Zhang C, Wang G. Integrated Analysis of Methylomic and Transcriptomic Data to Identify Potential Diagnostic Biomarkers for Major Depressive Disorder. Genes (Basel). 202,12(2):178. 11. Liang L, Zheng Y, Xie Y, Xiao L, Wang G. Oridonin ameliorates insulin resistance partially through inhibition of inflammatory response in rats subjected to chronic unpredictable mild stress. Int Immunopharmacol. 2021, 91:107298. 12. Liang L, Yu J, Xiao L, Wang G. Sustained low-dose prophylactic early erythropoietin for improvement of neurological outcomes in preterm infants:A systematic review and meta-analysis. J Affect Disord. 2021, 282:1187-1192. 13. Liang L, Chen J, Xiao L, Wang Q, Wang G. Mitochondrial modulators in the treatment of bipolar depression: a systematic review and meta-analysis. Transl Psychiatry. 2022, 12(1):4. 14. Bian H, Xiao L, Liang L, Xie Y, Wang H, Slevin M, Tu WJ, Wang G. Polydatin Prevents Neuroinflammation and Relieves Depression via Regulating Sirt1/HMGB1/NF-κB Signaling in Mice. Neurotox Res. 2022. 15. Zheng Y, Xiao L, Wang H, Chen Z, Wang G. A retrospective research on non-suicidal self-injurious behaviors among young patients diagnosed with mood disorders. Front Psychiatry. 2022,13:895892. 16. Han J, Shen M, Wan Q, Lv Z, Xiao L, Wang G. Risk factors for community-acquired pneumonia among inpatients with mental disorders in a tertiary general hospital. Front Psychiatry. 2022, 13:941198. 17. Liang L, Wang H, Hu Y, Bian H, Xiao L, Wang G. Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress. Phytother Res. 2022, 36(8):3335-3351. |
| Name | GAOHUA WANG |
| Date of birth | 1964 |
| Department | Department of Psychiatry, Renmin Hospital,Wuhan University. |
| Title | Professor, doctoral tutor |
| wgh6402@whu.edu.cn | |
| TEL | 027-88041911-86447 |
| Research Direction |
1. Depression ...... 2. Psychopharmacolog...... |
| Personal Profile | He is mainly engaged in the diagnosis and treatment of depression，He is currently the President of Renmin Hospital of Wuhan University and Director of the Institute of Neuropsychiatry of Hubei Province. Dr. Wang’s endeavor in the area has won himself several scientific awards, of which two were the Second grade award of Science and Technology Progress of Hubei Province and one was the first place winner of Su Zonghua Mental Health Award. Dr. Wang is currently the Deputy Chief Editor of Chinese Journal of Psychiatry and Editorial Committee member of Chinese Journal of Behavioral Medicine and Brain Science. Dr. Wang has undertaken and completed several research projects supported by the Stanley Medical Research Institute (SMRI, U.S.) and the National Natural Science Foundation. He hosted one key project in the National Science and Technology Pillar Program and Key Projects of Hubei Province. Currently several other major national scientific research projects are being progressed by Dr. Wang and his team. . In the academia, Dr. Wang is a highly acclaimed author with more than 200 peer-reviewed articles published in scientific journals, of which 100 indexed by SCI. He has also authored or coauthored several national-approved Psychiatry textbooks and monographs. Outside the professional realm, he is an active contributor to many Chinese authoritative newspapers and magazines with more than 100 articles devoted to psychology-related topics as well as others. He has educated 50 masters and 20 doctors. At present, there are14doctors and9Masters studying with him. |
| Selected Publications |
1.
Wei Y, Li J, Wang H, Wang G. NUCB2/nesfatin-1: Expression and functions in
the regulation of emotion and stress. Prog Neuropsychopharmacol Biol
Psychiatry. 2018, 81:221-227. 2. Nan C, Wang G, Wang H, Wang X, Liu Z, Xiao L, Bai H, Wu S. The P300 component decreases in a bimodal oddball task in individuals with depression: An event-related potentials study. Clin Neurophysiol. 2018, 129(12):2525-2533. 3. Bian H, Wang G, Huang J, Liang L, Zheng Y, Wei Y, Wang H, Xiao L, Wang H. Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat. J Neuroinflammation. 2020, 17(1):166. 4. Kang L, Li Y, Hu S, Chen M, Yang C, Yang BX, Wang Y, Hu J, Lai J, Ma X, Chen J, Guan L, Wang G, Ma H, Liu Z. The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus. Lancet Psychiatry. 2020, 7(3):e14. 5. Wu Z, Zhou L, Sun L, Xie Y, Xiao L, Wang H, Wang G. Brief postpartum separation from offspring promotes resilience to lipopolysaccharide challenge-induced anxiety and depressive-like behaviors and inhibits neuroinflammation in C57BL/6J dams. Brain Behav Immun. 2021, 95:190-202. 6. Bian H, Xiao L, Liang L, Xie Y, Wang H, Wang G. RGFP966 is protective against lipopolysaccharide-induced depressive-like behaviors in mice by inhibiting neuroinflammation and microglial activation. Int Immunopharmacol. 2021, 101(Pt B):108259. 7. Wei Y, Wang G, Chen J, Xiao L, Wu Z, He J, Zhang N. Maternal deprivation induces cytoskeletal alterations and depressive-like behavior in adult male rats by regulating the AKT/GSK3β/CRMP2 signaling pathway. Physiol Behav. 2021, 242:113625. 8. Xiang D, Sun S, Wang G, Liu Z. Effects of CRMP2 DNA Methylation in the Hippocampus on Depressive-Like Behaviors and Cytoskeletal Proteins in Rats. Front Cell Neurosci. 2021, 15:644663. 9. Liang L, Yu J, Xiao L, Wang G. Sustained low-dose prophylactic early erythropoietin for improvement of neurological outcomes in preterm infants:A systematic review and meta-analysis. J Affect Disord. 2021, 282:1187-1192. 10. Xie Y, Xiao L, Chen L, Zheng Y, Zhang C, Wang G. Integrated Analysis of Methylomic and Transcriptomic Data to Identify Potential Diagnostic Biomarkers for Major Depressive Disorder. Genes (Basel). 202,12(2):178. 11. Liang L, Zheng Y, Xie Y, Xiao L, Wang G. Oridonin ameliorates insulin resistance partially through inhibition of inflammatory response in rats subjected to chronic unpredictable mild stress. Int Immunopharmacol. 2021, 91:107298. 12. Liang L, Yu J, Xiao L, Wang G. Sustained low-dose prophylactic early erythropoietin for improvement of neurological outcomes in preterm infants:A systematic review and meta-analysis. J Affect Disord. 2021, 282:1187-1192. 13. Liang L, Chen J, Xiao L, Wang Q, Wang G. Mitochondrial modulators in the treatment of bipolar depression: a systematic review and meta-analysis. Transl Psychiatry. 2022, 12(1):4. 14. Bian H, Xiao L, Liang L, Xie Y, Wang H, Slevin M, Tu WJ, Wang G. Polydatin Prevents Neuroinflammation and Relieves Depression via Regulating Sirt1/HMGB1/NF-κB Signaling in Mice. Neurotox Res. 2022. 15. Zheng Y, Xiao L, Wang H, Chen Z, Wang G. A retrospective research on non-suicidal self-injurious behaviors among young patients diagnosed with mood disorders. Front Psychiatry. 2022,13:895892. 16. Han J, Shen M, Wan Q, Lv Z, Xiao L, Wang G. Risk factors for community-acquired pneumonia among inpatients with mental disorders in a tertiary general hospital. Front Psychiatry. 2022, 13:941198. 17. Liang L, Wang H, Hu Y, Bian H, Xiao L, Wang G. Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress. Phytother Res. 2022, 36(8):3335-3351. |
武汉大学人民医院
湖北省人民医院