导师介绍

 

姓名：夏豪                                                             

出生年月：1966年1月

单位：武汉大学人民医院心血管内科

职务、职称：心III科室副主任、主任医师、教授、博士生导师

邮箱：xiahao1966@163.com

联系电话：027-88041911转82148 

研究方向：

1.冠心病的基础与临床研究

2.介入心脏病学

 

个人简介：

主要从事急性心肌梗死等急危重症的救治、冠心病的介入诊断与治疗、人工心脏起搏器置入等临床与科研工作，主持国家科技支撑计划1项，国家自然科学基金2项，省级课题3项，市级课题1项。参编《内科学》教材等15部专著，在《Journal of the American Heart Association》、《Clinical Science》、《Journal of Lipid Research》、《British Journal of Pharmacology》、《Journal of Neurochemistry》、《Heart Rhythm》、《Nature Genetics》、《中华心血管病杂志》、《中国循环杂志》等杂志上发表论文200余篇，以第一作者或通讯作者发表论文100余篇，其中SCI论文近10余篇，影响因子超过50。已培养硕士生33名，博士生4名。目前正在培养的博士生4名，硕士生11名。

 

学术职务：

湖北省心血管疾病诊疗技术质量控制中心办公室副主任

湖北省青年科技协会理事

湖北省医学会医疗事故技术鉴定专家库成员

湖北省中西医结合学会心脑血管病专业委员会常委

湖北省卫生专业技术资格高评委

武汉医学会心血管病分会委员

 

教育履历：

1985.09-1990.06 同济医科大学临床医学本科生 获学士学位

1993.09-1996.06 武汉大学第一临床学院内科学硕士研究生 获硕士学位

1996.09-1999.06 武汉大学第一临床学院内科学博士研究生 获博士学位

 

工作履历：

1990.07-1993.08 武汉大学人民医院心血管内科住院医师

1999.07-2001.09 武汉大学人民医院心血管内科主治医师

2001.09-2006.12 武汉大学人民医院心血管内科副教授、副主任医师

2007.01-至今   武汉大学人民医院心血管内科教授、主任医师

 

成果获奖：

1. 《心肌重构的发病基础与临床防治》2014年获湖北省科技进步一等奖

 

代表性论著：

1．Liu X, Yang Q, Zhu LH, Liu J, Deng KQ, Zhu XY, Liu Y, Gong J, Zhang P, Li S, Xia H, S ZG. Carboxyl-Terminal Modulator Protein Ameliorates Pathological Cardiac Hypertrophy by Suppressing the AKT Signaling Pathway. Journal of the American Heart Association. 2018 Jun 26;7(13). pii: e008654. doi: 10.1161/JAHA.118.008654. 

2．Zhang C, Qin JJ, Gong FH, Tong JJ, Cheng WL, Wang H, Zhang Y, Zhu X, She ZG, Xia H, Zhu LH. Mindin deficiency in macrophages protects against foam cell formation and atherosclerosis by targeting LXR-β. Clinical Science. 2018 Jun 20;132(11):1199-1213. doi: 10.1042/CS20180033. Print 2018 Jun 15. 

3．Gong FH, Cheng WL, Wang H, Gao M, Qin JJ, Zhang Y, Li X, Zhu X, Xia H, She ZG. Reduced atherosclerosis lesion size, inflammatory response in miR-150 knockout mice via macrophage effects. Journal of Lipid Research. 2018 Apr;59(4):658-669. doi: 10.1194/jlr.M082651. Epub 2018 Feb 20. 

4．Yu L, Wang Y, Zhou X, Huang B, Wang M, Li X, Meng G, Yuan S, Xia H, Jiang H. Leptin injection into the left stellate ganglion augments ischemia-related ventricular arrhythmias via sympathetic nerve activation. Heart Rhythm. 2018 Apr;15(4):597-606. doi: 10.1016/j.hrthm.2017.12.003. Epub 2017 Dec 8. 

5．Zhang X, Li J, Qin JJ, Cheng WL, Zhu X, Gong FH, She Z, Huang Z, Xia H, Li H. Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages. Journal of Lipid Research. 2017 May;58(5):895-906. doi: 10.1194/jlr.M074112. Epub 2017 Mar 3.

6．Cheng WL, Yang Y, Zhang XJ, Guo J, Gong J, Gong FH, She ZG, Huang Z, Xia H, Li H. Dickkopf-3 Ablation Attenuates the Development of Atherosclerosis in ApoE-Deficient Mice. Journal of the American Heart Association. 2017 Feb 20;6(2). pii: e004690. doi: 10.1161/JAHA.116.004690.

7．Li L, Qin JJ, Guo S, Zhang P, Gong J, Zhang XJ, Zheng A, Xia H, Li H. Attenuation of cerebral ischemic injury in interferon regulatory factor 3-deficient rat. Journal of Neurochemistry. 2016 Feb;136(4):871-883. doi: 10.1111/jnc.13448. Epub 2015 Dec 21.

8．Wan N, Liu X, Zhang XJ, Zhao Y, Hu G, Wan F, Zhang R, Zhu X, Xia H, Li H. Toll-interacting protein contributes to mortality following myocardial infarction through promoting inflammation and apoptosis. British Journal of Pharmacology. 2015 Jul;172(13):3383-96. doi: 10.1111/bph.13130. Epub 2015 Apr 24.

9．Liu X, Wan N, Zhang XJ, Zhao Y, Zhang Y, Hu G, Wan F, Zhang R, Zhu X, Xia H, Li H. Vinexin-β exacerbates cardiac dysfunction post-myocardial infarction via mediating apoptotic and inflammatory responses. Clinical Science. 2015 Jun;128(12):923-36. doi: 10.1042/CS20140648. 

 

 

Name：Hao Xia 

Date of birth：Jan, 1966 

Department：Cardiovascular Department, Renmin Hospital, Wuhan University.

Title：Vice Director of Cardiology Ward III, Chief Physician, Professor, Doctoral Tutor

Email：xiahao1966@163.com

TEL：027-88041911转82148

Research Direction：

1. Basic and clinical study of coronary heart disease

2. Interventional cardiology

 

Personal Profile: 

He is mainly engaged in the clinical and scientific research on the treatment of acute myocardial infarction and other critical diseases, the interventional diagnosis and treatment of coronary heart disease and the implantation of artificial pacemaker, and has been awarded 1 item for the National Science and Technology Support Project, 2 items for the National Natural Science Foundation, 3 items for the provincial project, and 1 item for the municipal project. He has also participated in compiling 15 monographs, including teaching material Internal Medicine. Besides, there are more than 200 articles published in journals such as Journal of the American Heart Association, Clinical Science, Journal of Lipid Research, British Journal of Pharmacology, Journal of Neurochemistry, Heart Rhythm, Nature Genetics, Chinese Journal of Cardiology, Chinese Circulation Journal, and more than 100 papers published by the first author or corresponding author, including nearly 10 SCI papers with more than 50 influencing factors. By now, he has educated 33 masters and 4 doctors. At present, there are 4 doctors and 11 Masters studying with him.

 

Selected Publications:

1．Liu X, Yang Q, Zhu LH, Liu J, Deng KQ, Zhu XY, Liu Y, Gong J, Zhang P, Li S, Xia H, S ZG. Carboxyl-Terminal Modulator Protein Ameliorates Pathological Cardiac Hypertrophy by Suppressing the AKT Signaling Pathway. Journal of the American Heart Association. 2018 Jun 26;7(13). pii: e008654. doi: 10.1161/JAHA.118.008654. 

2．Zhang C, Qin JJ, Gong FH, Tong JJ, Cheng WL, Wang H, Zhang Y, Zhu X, She ZG, Xia H, Zhu LH. Mindin deficiency in macrophages protects against foam cell formation and atherosclerosis by targeting LXR-β. Clinical Science. 2018 Jun 20;132(11):1199-1213. doi: 10.1042/CS20180033. Print 2018 Jun 15. 

3．Gong FH, Cheng WL, Wang H, Gao M, Qin JJ, Zhang Y, Li X, Zhu X, Xia H, She ZG. Reduced atherosclerosis lesion size, inflammatory response in miR-150 knockout mice via macrophage effects. Journal of Lipid Research. 2018 Apr;59(4):658-669. doi: 10.1194/jlr.M082651. Epub 2018 Feb 20. 

4．Yu L, Wang Y, Zhou X, Huang B, Wang M, Li X, Meng G, Yuan S, Xia H, Jiang H. Leptin injection into the left stellate ganglion augments ischemia-related ventricular arrhythmias via sympathetic nerve activation. Heart Rhythm. 2018 Apr;15(4):597-606. doi: 10.1016/j.hrthm.2017.12.003. Epub 2017 Dec 8. 

5．Zhang X, Li J, Qin JJ, Cheng WL, Zhu X, Gong FH, She Z, Huang Z, Xia H, Li H. Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages. Journal of Lipid Research. 2017 May;58(5):895-906. doi: 10.1194/jlr.M074112. Epub 2017 Mar 3.

6．Cheng WL, Yang Y, Zhang XJ, Guo J, Gong J, Gong FH, She ZG, Huang Z, Xia H, Li H. Dickkopf-3 Ablation Attenuates the Development of Atherosclerosis in ApoE-Deficient Mice. Journal of the American Heart Association. 2017 Feb 20;6(2). pii: e004690. doi: 10.1161/JAHA.116.004690.

7．Li L, Qin JJ, Guo S, Zhang P, Gong J, Zhang XJ, Zheng A, Xia H, Li H. Attenuation of cerebral ischemic injury in interferon regulatory factor 3-deficient rat. Journal of Neurochemistry. 2016 Feb;136(4):871-883. doi: 10.1111/jnc.13448. Epub 2015 Dec 21.

8．Wan N, Liu X, Zhang XJ, Zhao Y, Hu G, Wan F, Zhang R, Zhu X, Xia H, Li H. Toll-interacting protein contributes to mortality following myocardial infarction through promoting inflammation and apoptosis. British Journal of Pharmacology. 2015 Jul;172(13):3383-96. doi: 10.1111/bph.13130. Epub 2015 Apr 24.

9．Liu X, Wan N, Zhang XJ, Zhao Y, Zhang Y, Hu G, Wan F, Zhang R, Zhu X, Xia H, Li H. Vinexin-β exacerbates cardiac dysfunction post-myocardial infarction via mediating apoptotic and inflammatory responses. Clinical Science. 2015 Jun;128(12):923-36. doi: 10.1042/CS20140648.