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  • 陈长征 眼科学
    院长助理,眼科中心主任,副教授,博士生导师
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    导师介绍

    姓名 陈长征
    出生年月 1971年2月
    单位 武汉大学人民医院眼科
    所属学科 临床医学-外科学
    职务、职称及头衔 院长助理,眼科中心主任,副教授,博士生导师
    E-mail whuchenchzh@163.com
    联系方式 13072765173
    研究方向 1.眼底病
    2.神经眼科疾病
    个人简介 毕业于中山大学眼科中心,获得博士学位,曾赴日本名古屋大学医学部、美国犹他大学moran眼科中心和德国明斯特大学学习交流。主要从事眼底疾病的诊疗和科研工作,承担和参加国家自然科学基金省部级科研项目4项。发表论文150余篇(以通讯作者发表SCI 30余篇),主编专著3部,参编专著3部,主译专著1部。曾获湖北省科技进步奖二等奖一项、三等奖两项和华夏科技进步奖一项。已培养硕士生17名;目前正在培养硕士生9名、博士生一名。
    学术任职与荣誉 中国医师协会眼科医师分会常务委员
    中华医学会眼科分会神经眼科学组委员
    中国医师协会眼科分会神经眼科专业委员会副主任委员
    湖北省医师协会眼科医师分会主任委员
    湖北省医学会眼科分会副主任委员
    湖北省高级专家协会委员
    《中华眼底病杂志》、《中华眼视光杂志》等编委
    教育履历 1988.09-1993.06武汉大学医学院临床医学专业本科生获学士学位
    1997.09-2000.06武汉大学医学院眼科学硕士研究生获硕士学位
    2000.09-2003.06中山大学眼科学博士研究生获博士学位
    工作履历 1993.09-1997.06武汉大学中南医院住院医师
    2004.04-2004.08日本名古屋大学医学部访问学者
    2009.10-2010.03美国犹他大学moran眼科中心访问学者
    2013.01-2013.02德国明斯特大学访问学者
    2016.05-至今 武汉大学人民医院院长助理
    2018.09-至今 武汉大学人民医院眼科中心主任
    成果获奖 1.《早产儿视网膜病变发病机制及防治策略》2014年华夏科技进步奖
    2.《早产儿视网膜病变发病机制及防治策略》2014年武汉市科技进步三等奖
    3.《早产儿视网膜病变发病机制及防治策略》2013年湖北省科技进步三等奖
    4.《曲安奈德在玻璃体视网膜疾病中应用研究》2008年湖北省科技进步二等奖
    代表性论著 [1]  Zhou, Y., Duan, C., Zeng, Y., Tong, Y., Nie, Y., Yang, Y., Chen, Z., &Chen, C*.(2020/04). Ocular Findings and Proportion with Conjunctival SARS-COV-2 in COVID-19 Patients. Ophthalmology.(IF=12.079,中科院一区)
    [2]  He, L., Zeng, Y., Zeng, C., Zhou, Y., Li, Y., Xie, X., Xu, W., Luo, W., Hu, J., Yi, Z., Wang, X., Tang, S., Xu, L., &Chen, C*.(2020/04). Positive Rate of Serology and RT-PCR for COVID-19 among healthcare workers during different periods in Wuhan, China. J Infect.(IF=6.072,JCR一区)
    [3]  Jiang J, Sun G, Miao Q, Li B, Wang D,Yuan J andChen C*.(2021/12). Observation of Peripapillary Choroidal Vascularity in Natural Disease Course and After Gene Therapy for Leber’s Hereditary Optic Neuropathy. Front. Med.(IF=5.091,JCR一区)
    [4]  Sun, G., Wang, X., Jiang, J., Yi, Z., Fu, M., Yang, X., Zheng, H., &Chen, C*. (2021/08). Association of Subregional Quantitative Ultra-widefield Fluorescence Angiography Characteristics With the Occurrence of Diabetic Macular Edema and Proliferative Diabetic Retinopathy. Front Med (Lausanne).(IF=5.091,JCR一区)
    [5]  Ting Chen, Jiayi Song, Hongli Liu, Hongmei Zheng,Changzheng Chen*.(2021/05). Positive Epstein-Barr virus detection in coronavirus disease 2019 (COVID-19) patients. Sci Rep.(IF=4.379,JCR一区)
    [6]  He L, Yi Z, Wang X, Liu J, Zheng H,Chen C*.(2020/04). CLINICAL APPLICATION OF MULTICOLOR IMAGING IN CENTRAL SEROUS CHORIORETINOPATHY. Retina.(IF=4.256,JCR一区)
    [7]  Sun, G., Jiang, J., Yi, Z., Wang, X., Miao, Q., Xu, A., He, L &Chen, C*.(2021/06). NEW INSIGHTS INTO THE ASSOCIATION BETWEEN CHOROIDAL VESSELS AND CHORIOCAPILLARIS IN NORMAL EYES. Retina.(IF=4.256,JCR一区)
    [8]  Zeng Y, Yin X, Xing Y,Chen C*.(2021/06). Identification of Diagnostic Biomarkers and Their Correlation with Immune Infiltration in Age-Related Macular Degeneration. Diagnostics (Basel).(IF=3.706, JCR二区)
    [9]  Zhou, Y., Zeng, Y., &Chen, C*.(2020/08). Presence of SARS-CoV-2 RNA in isolation ward environment 28 days after exposure. Int J Infect Dis.(IF=3.623,JCR二区)
    [10]  Li L, He T, Su Y, Wu L,Chen C*. (2021/11)The Results of Pars Plana Vitrectomy in the Treatment of Intraocular Retinoblastoma: A Retrospective Study and Literature Review. Technol Cancer Res Treat.(IF=3.399,JCR三区)
    [11]  Hua D, Xu Y, Heiduschka P, Zhang W, Zhang X, Zeng X, Zhu X, He T, Zheng H, Xiao X, Xing Y, Chen Z,Chen C*.(2021/03). Retina Vascular Perfusion Dynamics During Exercise With and Without Face Masks in Healthy Young Adults: An OCT Angiography Study. Transl Vis Sci Technol.(IF=3.283,JCR二区)
    [12]  Xu, Y., Su, Y., Li, L., Qi, H., Zheng, H., &Chen, C*.(2017/04). Effect of Photodynamic Therapy on Optical Coherence Tomography Angiography in Eyes with Chronic Central Serous Chorioretinopathy. Ophthalmologica.(IF=3.250, JCR二区)
    [13]  Li, L., Su, Y., Feng, C., Zheng, H. M., & Xing, Y. Q,Chen, C. Z*.(2011/10). Sweep pattern visual evoked potential acuity in children during their periods of visual development. Ophthalmologica.(IF=3.250, JCR二区)
    [14]  Wang, X., Sun, G., Yi, Z., Xu, A., He, L., Jiang, J., Zheng, H., &Chen, C*.(2021/08). Leakage index on ultra-widefield fluorescence angiography in different regions of retina and its correlation with cystoid macular edema in central retinal vein occlusion eyes. Graefes Arch Clin Exp Ophthalmol.(IF=3.177,JCR二区)
    [15]  Amin Xu, Gongpeng Sun, Chaoye Duan, Zhen Chen andChangzheng Chen*.(2021/10). Quantitative Assessment of Three-Dimensional Choroidal Vascularity and Choriocapillaris Flow Signal Voids in Myopic Patients Using SS-OCTA. Diagnostics.(IF=2.955, JCR二区)
    [16]  Wang, X., Xu, A., Yi, Z., He, L., Liu, J., Zheng, H., &Chen, C*.(2020/05). Observation of the far peripheral retina of normal eyes by ultra-wide field fluorescein angiography. Eur J Ophthalmol.(IF=2.597,JCR三区)
    [17]  Li, L., Li, W. Z., Yi, Z. H., Zhou, Y. Y,Chen, C*.(2015/04). Is aspirin use associated with age-related macular degeneration? A meta-analysis. J Clin Pharm Ther.(IF=2.512, JCR三区)
    [18]  Li L,Chen C*. Contribution of acute-phase reaction proteins to the diagnosis and treatment of 2019 novel coronavirus disease (COVID-19). Epidemiol Infect. 2020.(IF=2.451,中科院三区)
    [19]  Yi, Z., Su, Y., Zhou, Y., Zheng, H., Ye, M., Xu, Y., &Chen, C*.(2016/08). Effects of Intravitreal Ranibizumab in the Treatment of Retinopathy of Prematurity in Chinese Infants. Curr Eye Res.(IF=2.424,中科院三区)
    [20]  Yi, Z., Su, Y., Li, L., Zhou, Y,Chen, C*.(2015/11). Changes in Clotting Time, Plasma Fibrinogen Levels, and Blood Viscosity After Administration of Ranibizumab for Treatment of Choroidal Neovascularization. Curr Eye Res.(IF=2.424,中科院三区)
    [21]  Chen, T., Li, G., Liu, H., Wan, W., Zheng, H., &Chen, C*.(2021/03). Clinical characteristics of 132 healthcare worker cases with COVID-19: A retrospective study from a single center in Wuhan, China. J Med Virol.(IF=2.327,中科院四区)
    [22]  Liu, J., Li, L., Xu, Y., Yi, Z., He, L., Zheng, H,Chen, C*.(2020/10). Assessment of choriocapillary blood flow changes in response to half-dose photodynamic therapy in chronic central serous chorioretinopathy using optical coherence tomography angiography. BMC Ophthalmol.(IF=2.209,JCR三区)
    [23]  Ting Chen, Hongmei Zheng, Yunyun Wang, Junyi Hu,Changzheng Chen*.(2020/04). Bilateral and multiple sub-internal limiting membrane hemorrhages in a familial retinal arteriolar tortuosity patient by Valsalva-like mechanism: an observational case report. BMC Ophthalmol.(IF=2.209,JCR三区)
    [24]  Xu A,Chen C*.(2020/11). Clinical application of ultra-widefield fundus autofluorescence. Int Ophthalmol.(IF=2.031,中科院三区)
    [25]  Liu, J., Li, L., Yi, Z., Zheng, H. , &Chen, C*.(2020/11). Peripapillary and Macular Flow Changes in Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) by Optical Coherence Tomography Angiography (OCT-A).J Ophthalmol.(IF=1.909, JCR三区)
    [26]  Yi Z, Chen L, Wang X,Chen C*, Xing Y.(2020/06).Protective Effects of Intravitreal Injection of the Rho-Kinase Inhibitor Y-27632 in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rAION). J Ophthalmol.(IF=1.909, JCR三区)
    [27]  Yi, Z., , Wang, X., Liu, J., He, L., Zheng, H., Xing, Y. &Chen, C*.(2020/01).Assessment of the Dynamic Alteration of Choriocapillaris Vessel Density after Focal Laser Photocoagulation with OCT Angiography. J Ophthalmol.(IF=1.909, JCR三区)
    [28]  Zeng, Y., He, T., Liu, J., Li, Z., Xie, F.,Chen, C*., & Xing, Y.(2020/11). Bioinformatics analysis of multi-omics data identifying molecular biomarker candidates and epigenetically regulatory targets associated with retinoblastoma. Medicine (Baltimore).(IF=1.889,JCR三区)
    [29]  Jiang JW, Yi ZHZ, Wang XL, Liu JJ, Sun GP,Chen CZ*.(2021/08). Quantitative analysis of retinal vasculature in normal eyes using ultra-widefield fluorescein angiography.Int J Ophthalmol.(IF=1.779,中科院三区)
    [30]  Zhou, Y. Y. Z., Su, Y., Li, L., Yi, Z. H., Qi, H., Weng, M., Xing, Y. Q.,Chen, C*.(2014/02). Effect of EGb761 on light-damaged retinal pigment epithelial cells. Int J Ophthalmol. (IF=1.779,中科院三区)
    Name ChangZheng Chen
    Date of birth February,1971
    Department Ophthalmology Department
    Title Assistant President of Renmin Hospital of Wuhan University,Director of Ophthalmic Center, Assistant Professor, Doctoral tutor
    Email whuchenchzh@163.com
    TEL 13072765173
    Research Direction 1. Retinal diseases
    2. Neuro-ophthalmology
    Personal Profile Dr.Chen graduated from the Eye Center of Sun Yat-sen University, where he got a doctor’s degree. Then he went to Nagoya University in Japan, University of Utah and University of munster for exchange study. Now Dr.Chen is mainly engaged in the diagnosis and treatment of ocular fundus diseases. He has undertaken and participated in 4 research projects at the ministerial level of the National Natural Science Foundation of China. So far more than 150 papers have been published by him, including over 30 SCI articles(as corresponding author). He has also involved in compiling 3 monograph, 3 monograph and 1 monographs. Besides, Dr. Chen has won one second prize,two third prizes of Hubei science and technology progress award and one Huaxia science and technology progress award. He has cultivated 17 master students. At present, he is training 9 master students and 1 doctoral student.
    Selected Publications [1]  Zhou, Y., Duan, C., Zeng, Y., Tong, Y., Nie, Y., Yang, Y., Chen, Z., &Chen, C*.(2020/04). Ocular Findings and Proportion with Conjunctival SARS-COV-2 in COVID-19 Patients. Ophthalmology.(IF=12.079)
    [2]  He, L., Zeng, Y., Zeng, C., Zhou, Y., Li, Y., Xie, X., Xu, W., Luo, W., Hu, J., Yi, Z., Wang, X., Tang, S., Xu, L., &Chen, C*.(2020/04). Positive Rate of Serology and RT-PCR for COVID-19 among healthcare workers during different periods in Wuhan, China. J Infect.(IF=6.072,JCR一区)
    [3]  Jiang J, Sun G, Miao Q, Li B, Wang D,Yuan J andChen C*.(2021/12). Observation of Peripapillary Choroidal Vascularity in Natural Disease Course and After Gene Therapy for Leber’s Hereditary Optic Neuropathy. Front. Med.(IF=5.091)
    [4]  Sun, G., Wang, X., Jiang, J., Yi, Z., Fu, M., Yang, X., Zheng, H., &Chen, C*. (2021/08). Association of Subregional Quantitative Ultra-widefield Fluorescence Angiography Characteristics With the Occurrence of Diabetic Macular Edema and Proliferative Diabetic Retinopathy. Front Med (Lausanne).(IF=5.091)
    [5]  Ting Chen, Jiayi Song, Hongli Liu, Hongmei Zheng,Changzheng Chen*.(2021/05). Positive Epstein-Barr virus detection in coronavirus disease 2019 (COVID-19) patients. Sci Rep.(IF=4.379)
    [6]  He L, Yi Z, Wang X, Liu J, Zheng H,Chen C*.(2020/04). CLINICAL APPLICATION OF MULTICOLOR IMAGING IN CENTRAL SEROUS CHORIORETINOPATHY. Retina.(IF=4.256)
    [7]  Sun, G., Jiang, J., Yi, Z., Wang, X., Miao, Q., Xu, A., He, L &Chen, C*.(2021/06). NEW INSIGHTS INTO THE ASSOCIATION BETWEEN CHOROIDAL VESSELS AND CHORIOCAPILLARIS IN NORMAL EYES. Retina.(IF=4.256)
    [8]  Zeng Y, Yin X, Xing Y,Chen C*.(2021/06). Identification of Diagnostic Biomarkers and Their Correlation with Immune Infiltration in Age-Related Macular Degeneration. Diagnostics (Basel).(IF=3.706)
    [9]  Zhou, Y., Zeng, Y., &Chen, C*.(2020/08). Presence of SARS-CoV-2 RNA in isolation ward environment 28 days after exposure. Int J Infect Dis.(IF=3.623)
    [10]  Li L, He T, Su Y, Wu L,Chen C*. (2021/11)The Results of Pars Plana Vitrectomy in the Treatment of Intraocular Retinoblastoma: A Retrospective Study and Literature Review. Technol Cancer Res Treat.(IF=3.399)
    [11]  Hua D, Xu Y, Heiduschka P, Zhang W, Zhang X, Zeng X, Zhu X, He T, Zheng H, Xiao X, Xing Y, Chen Z,Chen C*.(2021/03). Retina Vascular Perfusion Dynamics During Exercise With and Without Face Masks in Healthy Young Adults: An OCT Angiography Study. Transl Vis Sci Technol.(IF=3.283)
    [12]  Xu, Y., Su, Y., Li, L., Qi, H., Zheng, H., &Chen, C*.(2017/04). Effect of Photodynamic Therapy on Optical Coherence Tomography Angiography in Eyes with Chronic Central Serous Chorioretinopathy. Ophthalmologica.(IF=3.250)
    [13]  Li, L., Su, Y., Feng, C., Zheng, H. M., & Xing, Y. Q,Chen, C. Z*.(2011/10). Sweep pattern visual evoked potential acuity in children during their periods of visual development. Ophthalmologica.(IF=3.250)
    [14]  Wang, X., Sun, G., Yi, Z., Xu, A., He, L., Jiang, J., Zheng, H., &Chen, C*.(2021/08). Leakage index on ultra-widefield fluorescence angiography in different regions of retina and its correlation with cystoid macular edema in central retinal vein occlusion eyes. Graefes Arch Clin Exp Ophthalmol.(IF=3.177)
    [15]  Amin Xu, Gongpeng Sun, Chaoye Duan, Zhen Chen andChangzheng Chen*.(2021/10). Quantitative Assessment of Three-Dimensional Choroidal Vascularity and Choriocapillaris Flow Signal Voids in Myopic Patients Using SS-OCTA. Diagnostics.(IF=2.955)
    [16]  Wang, X., Xu, A., Yi, Z., He, L., Liu, J., Zheng, H., &Chen, C*.(2020/05). Observation of the far peripheral retina of normal eyes by ultra-wide field fluorescein angiography. Eur J Ophthalmol.(IF=2.597)
    [17]  Li, L., Li, W. Z., Yi, Z. H., Zhou, Y. Y,Chen, C*.(2015/04). Is aspirin use associated with age-related macular degeneration? A meta-analysis. J Clin Pharm Ther.(IF=2.512)
    [18]  Li L,Chen C*. Contribution of acute-phase reaction proteins to the diagnosis and treatment of 2019 novel coronavirus disease (COVID-19). Epidemiol Infect. 2020.(IF=2.451)
    [19]  Yi, Z., Su, Y., Zhou, Y., Zheng, H., Ye, M., Xu, Y., &Chen, C*.(2016/08). Effects of Intravitreal Ranibizumab in the Treatment of Retinopathy of Prematurity in Chinese Infants. Curr Eye Res.(IF=2.424)
    [20]  Yi, Z., Su, Y., Li, L., Zhou, Y,Chen, C*.(2015/11). Changes in Clotting Time, Plasma Fibrinogen Levels, and Blood Viscosity After Administration of Ranibizumab for Treatment of Choroidal Neovascularization. Curr Eye Res.(IF=2.424)
    [21]  Chen, T., Li, G., Liu, H., Wan, W., Zheng, H., &Chen, C*.(2021/03). Clinical characteristics of 132 healthcare worker cases with COVID-19: A retrospective study from a single center in Wuhan, China. J Med Virol.(IF=2.327)
    [22]  Liu, J., Li, L., Xu, Y., Yi, Z., He, L., Zheng, H,Chen, C*.(2020/10). Assessment of choriocapillary blood flow changes in response to half-dose photodynamic therapy in chronic central serous chorioretinopathy using optical coherence tomography angiography. BMC Ophthalmol.(IF=2.209)
    [23]  Ting Chen, Hongmei Zheng, Yunyun Wang, Junyi Hu,Changzheng Chen*.(2020/04). Bilateral and multiple sub-internal limiting membrane hemorrhages in a familial retinal arteriolar tortuosity patient by Valsalva-like mechanism: an observational case report. BMC Ophthalmol.(IF=2.209)
    [24]  Xu A,Chen C*.(2020/11). Clinical application of ultra-widefield fundus autofluorescence. Int Ophthalmol.(IF=2.031)
    [25]  Liu, J., Li, L., Yi, Z., Zheng, H. , &Chen, C*.(2020/11). Peripapillary and Macular Flow Changes in Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) by Optical Coherence Tomography Angiography (OCT-A).J Ophthalmol.(IF=1.909)
    [26]  Yi Z, Chen L, Wang X,Chen C*, Xing Y.(2020/06).Protective Effects of Intravitreal Injection of the Rho-Kinase Inhibitor Y-27632 in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rAION). J Ophthalmol.(IF=1.909)
    [27]  Yi, Z., , Wang, X., Liu, J., He, L., Zheng, H., Xing, Y. &Chen, C*.(2020/01).Assessment of the Dynamic Alteration of Choriocapillaris Vessel Density after Focal Laser Photocoagulation with OCT Angiography. J Ophthalmol.(IF=1.909)
    [28]  Zeng, Y., He, T., Liu, J., Li, Z., Xie, F.,Chen, C*., & Xing, Y.(2020/11). Bioinformatics analysis of multi-omics data identifying molecular biomarker candidates and epigenetically regulatory targets associated with retinoblastoma. Medicine (Baltimore).(IF=1.889)
    [29]  Jiang JW, Yi ZHZ, Wang XL, Liu JJ, Sun GP,Chen CZ*.(2021/08). Quantitative analysis of retinal vasculature in normal eyes using ultra-widefield fluorescein angiography.Int J Ophthalmol.(IF=1.779)
    [30]  Zhou, Y. Y. Z., Su, Y., Li, L., Yi, Z. H., Qi, H., Weng, M., Xing, Y. Q.,Chen, C*.(2014/02). Effect of EGb761 on light-damaged retinal pigment epithelial cells. Int J Ophthalmol. (IF=1.779)