徐昌武
心内
副主任医师、硕士研究生导师
副主任医师、硕士研究生导师
导师介绍
| 姓名 | 徐昌武 |
| 出生年月 | 1987年1月 |
| 单位 | 武汉大学人民医院/武汉大学第一临床学院 |
| 所属学科 | 临床医学-内科学-心血管病学 |
| 职务、职称及头衔 | 副主任医师、硕士研究生导师 |
| xuchangwu@whu.edu.cn | |
| 联系方式 | 027-88041911-81790 |
| 研究方向 |
1.血管损伤、衰老与修复 2.心肌缺血再灌注损伤 3.冠心病的转化医学和临床研究 |
| 个人简介 | |
| 从事冠心病相关基础及临床研究；对冠心病、高血压、心力衰竭、心脏瓣膜病等心血管疾病的诊断与治疗有丰富临床经验；擅长急性心肌梗死、急性心力衰竭、心源性休克等心血管危急重症的临床救治；擅长冠心病和心脏瓣膜病的微创介入治疗。 | |
| 学术任职与荣誉 | |
| 兼任湖北省急性心血管病医疗救治中心秘书、湖北省微循环学会心血管专业委员会委员、湖北省暴发性心肌炎质量控制中心专家委员会委员、湖北省心血管疑难重症专家沙龙委员、武汉市医学会心血管病分会急重症学组委员。 | |
| 教育履历 | |
|
2004.9-2009.6 武汉大学 临床医学本科 2009.9-2014.6 武汉大学 内科学硕博连读 2012.10-2013.12 美国芝加哥大学 国家公派联合培养 |
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| 工作履历 | |
|
2014.07-2014.11 武汉大学人民医院 心血管内科住院医师 2014.12-2019.11 武汉大学人民医院 心血管内科主治医师 2019.12-至今 武汉大学人民医院 心血管内科副主任医师 |
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| 成果获奖 | |
| 参获华夏医学科学进步一等奖1项 | |
| 代表性论著 | |
|
1. Qiu L, Liu X, Xia H, Xu C. Downregulation of
P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal
Pathway Activation. Int J Mol Sci. 2022 Oct 20;23(20):12574. 2. Wu B, Xu C, Ding HS, Qiu L, Gao JX, Li M, Xiong Y, Xia H, Liu X. Galangin inhibits neointima formation induced by vascular injury via regulating the PI3K/AKT/mTOR pathway. Food Funct. 2022 Nov 28;13(23):12077-12092. 3. Qiu L, Liu X, Li W, Liu Z, Xu C, Xia H. Downregulation of p300/CBP-associated factor inhibits cardiomyocyte apoptosis via suppression of NF-κB pathway in ischaemia/reperfusion injury rats. J Cell Mol Med. 2021 Nov;25(21):10224-10235. 4. He W, Xu C, Wang X et al. Development and validation of a risk prediction nomogram for in-stent restenosis in patients undergoing percutaneous coronary intervention. BMC Cardiovascular Disorders. 2021;21:435. 5. Zhao Q, Song W, Huang J, Wang D, Xu C. Metformin decreased myocardial fibrosis and apoptosis in hyperhomocysteinemia -induced cardiac hypertrophy. Current Research in Translational Medicine. 2021;69:103270. 6. Qiu L, Xu C, Xia H, Chen J, Liu H, Jiang H. Downregulation of P300/CBP-Associated Factor Attenuates Myocardial Ischemia-Reperfusion Injury Via Inhibiting Autophagy. International Journal of Medical Sciences. 2020;17:1196-1206. 7. Qiu L, Xu C, Chen J, Li Q, Jiang H. Downregulation of the transcriptional co-activator PCAF inhibits the proliferation and migration of vascular smooth muscle cells and attenuates NF-κB-mediated inflammatory responses. Biochemical and Biophysical Research Communications. 2019;513:41-48. 8. Qiu L, Xu C, Jiang H, Li W, Tong S, Xia H. Cantharidin Attenuates the Proliferation and Migration of Vascular Smooth Muscle Cells through Suppressing Inflammatory Response. Biological & Pharmaceutical Bulletin. 2019;42:34-42. |
| Name | XU Changwu |
| Date of birth | January, 1987 |
| Department | Cardiovascular Department, Renmin Hospital, Wuhan University |
| Title | Associate Chief Physician |
| xuchangwu@whu.edu.cn | |
| TEL | 027-88041911-81790 |
| Research Direction | |
|
1.Vascular Injury, Aging and Repair 2. Myocardial Ischemia Reperfusion Injury 3.Translational and Clinical Research of Coronary Heart Disease |
|
| Personal Profile | |
| Dr. Xu has been engaged in basic, translational and clinical research related to coronary heart disease since 2009. Dr. Xu obtained two grants from National Natural Science Foundation of China and Hubei Provincial Natural Science Foundation. Dr. Xu published many relevant articles with high impact factor in recent years. | |
| Selected Publications | |
|
1. Qiu L, Liu X, Xia H, Xu C. Downregulation of
P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal
Pathway Activation. Int J Mol Sci. 2022 Oct 20;23(20):12574. 2. Wu B, Xu C, Ding HS, Qiu L, Gao JX, Li M, Xiong Y, Xia H, Liu X. Galangin inhibits neointima formation induced by vascular injury via regulating the PI3K/AKT/mTOR pathway. Food Funct. 2022 Nov 28;13(23):12077-12092. 3. Qiu L, Liu X, Li W, Liu Z, Xu C, Xia H. Downregulation of p300/CBP-associated factor inhibits cardiomyocyte apoptosis via suppression of NF-κB pathway in ischaemia/reperfusion injury rats. J Cell Mol Med. 2021 Nov;25(21):10224-10235. 4. He W, Xu C, Wang X et al. Development and validation of a risk prediction nomogram for in-stent restenosis in patients undergoing percutaneous coronary intervention. BMC Cardiovascular Disorders. 2021;21:435. 5. Zhao Q, Song W, Huang J, Wang D, Xu C. Metformin decreased myocardial fibrosis and apoptosis in hyperhomocysteinemia -induced cardiac hypertrophy. Current Research in Translational Medicine. 2021;69:103270. 6. Qiu L, Xu C, Xia H, Chen J, Liu H, Jiang H. Downregulation of P300/CBP-Associated Factor Attenuates Myocardial Ischemia-Reperfusion Injury Via Inhibiting Autophagy. International Journal of Medical Sciences. 2020;17:1196-1206. 7. Qiu L, Xu C, Chen J, Li Q, Jiang H. Downregulation of the transcriptional co-activator PCAF inhibits the proliferation and migration of vascular smooth muscle cells and attenuates NF-κB-mediated inflammatory responses. Biochemical and Biophysical Research Communications. 2019;513:41-48. 8. Qiu L, Xu C, Jiang H, Li W, Tong S, Xia H. Cantharidin Attenuates the Proliferation and Migration of Vascular Smooth Muscle Cells through Suppressing Inflammatory Response. Biological & Pharmaceutical Bulletin. 2019;42:34-42. |
武汉大学人民医院
湖北省人民医院