武汉大学人民医院湖北省人民医院

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高文蔚重症
副主任医师，硕士生导师

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导师介绍

姓名	高文蔚
出生年月	1985年8月
单位	武汉大学人民医院重症医学科
所属学科	临床医学-重症医学
职务、职称及头衔	副主任医师，硕士生导师
E-mail	wenwei_gao@163.com
联系方式	027-88041911转81075或13797080458
研究方向	1.危重症重要脏器保护 2.脑缺血再灌注损伤
个人简介	已从事急危重症的临床救治和研究工作12年，主持国家自然科学基金1项、湖北省自然科学基金2项；以第一/通讯作者发表论文18篇，其中SCI论文8篇；获批实用新型专利4项；参获湖北省科技进步二等奖2项、湖北省科技进步三等奖1项、武汉市科技进步二等奖1项。
学术任职与荣誉	武汉病理生理学会委员 2023年武汉大学人民医院优秀共产党员 2022年度武汉大学人民医院核心人才奖 2018、2020、2022年度武汉大学人民医院先进工作者
教育履历	2004.09-2011.06武汉大学第一临床学院临床医学七年制获学士、硕士学位 2012.09-2014.12武汉大学第一临床学院麻醉学博士研究生获博士学位
工作履历	2011.07-2014.04武汉大学人民医院重症医学科住院医师 2014.05-2018.11武汉大学人民医院重症医学科主治医师 2018.12-至今武汉大学人民医院重症医学科副主任医师
成果获奖	1.《缺血性脑损伤与免疫调控的机制与防治》2020年获湖北省科技进步三等奖 2.《围术期糖尿病肾脏再灌注损伤易损性增加的机制与防治探讨》2017年获湖北省科技进步二等奖 3.《缺血再灌注对多脏器损伤影响的机制与防治探讨》2014年获湖北省科技进步二等奖 4.《心脏大血管手术所致多脏器损伤的机制与防治探讨》2015年获武汉市科技进步二等奖
代表性论著	1.Wang L, Xiong X, Zhang X, Ye Y, Jian Z, Gao W, Gu L. Sodium Tanshinone IIA Sulfonate Protects Against Cerebral Ischemia-reperfusion Injury by Inhibiting Autophagy and Inflammation. Neuroscience. 2020; 441: 46-57. 2.Li M, Gao WW, Liu L, Gao Y, Wang YF, Zhao B, Xiong XX. The Akt/glycogen synthase kinase-3β pathway participates in the neuroprotective effect of interleukin-4 against cerebral ischemia/reperfusion injury. Neural Regen Res. 2020; 15(9): 1716-1723. 3.Zhao B, Yuan Q, Hou JB, Xia ZY, Zhan LY, Li M, Jiang M, Gao WW, Liu L. Inhibition of HDAC3 Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice In Vivo and In Vitro. J Diabetes Res. 2019; 2019: 8520856. 4.Zhao B, Liu L, Leng Y, Yuan Q, Hou J, Wu Y, Gao W. The Role of Histone Deacetylase Inhibitors in Regulation of Akt/GSK-3β Signaling Pathway in Mice Following Transient Focal Cerebral Ischemia. Acta Cir Bras. 2017; 32(10): 862-872 . 5.Gao WW, He YH, Liu L, Yuan Q, Wang YF, Zhao B. BIS Monitoring on Intraoperative Awareness: A Meta-analysis. Curr Med Sci. 2018; 38(2): 349-353. 6.Gao WW, He ZG, Zhao B, Tang CL, Xiao Y, Jiang M, Xia ZY. Different concentrations of bupivacaine on postoperative urinary retention in patients undergoing subarachnoid anesthesia. Int J Clin Exp Med. 2017; 10(7): 10840-10845. 7.Gao W, Zhao B, Liu L, Yuan Q, Wu X, Xia Z. Myocardial ischemic post-conditioning protects the lung against myocardial ischemia/reperfusion-induced damage by activating GSK-3β. Acta Cir Bras. 2017; 32(5): 376-387.

Name	WENWEI GAO
Date of birth	August，1985
Department	Department of Critical Care Mdicine,Renmin Hospital,Wuhan University.
Title	Associate Chief Physician,Master tutor
Email	wenwei_gao@163.com
TEL	027-88041911-81075 or 13797080458
Research Direction	1. Organ function protection in critically ill patients 2. Mechanism and prevention of cerebral ischemia reperfusion injury
Personal Profile	She has been engaged in clinical treatment and research of acute and critical diseases for 12 years,took charge one fund of NSFC and two hubei province natural science fund projects, published 18 articles as first/corresponding author,including 8 SCI papers,and obtained 4 patents.Her research achievements have been awarded the Second Prize of Science and Technology Progress of Hubei Province twice,the Third Prize of Science and Technology Progress of Hubei Province once,and the Second Prize of Science and Technology Progress of Wuhan City once.
Selected Publications	1.Wang L, Xiong X, Zhang X, Ye Y, Jian Z, Gao W, Gu L. Sodium Tanshinone IIA Sulfonate Protects Against Cerebral Ischemia-reperfusion Injury by Inhibiting Autophagy and Inflammation. Neuroscience. 2020; 441: 46-57. 2.Li M, Gao WW, Liu L, Gao Y, Wang YF, Zhao B, Xiong XX. The Akt/glycogen synthase kinase-3β pathway participates in the neuroprotective effect of interleukin-4 against cerebral ischemia/reperfusion injury. Neural Regen Res. 2020; 15(9): 1716-1723. 3.Zhao B, Yuan Q, Hou JB, Xia ZY, Zhan LY, Li M, Jiang M, Gao WW, Liu L. Inhibition of HDAC3 Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice In Vivo and In Vitro. J Diabetes Res. 2019; 2019: 8520856. 4.Zhao B, Liu L, Leng Y, Yuan Q, Hou J, Wu Y, Gao W. The Role of Histone Deacetylase Inhibitors in Regulation of Akt/GSK-3β Signaling Pathway in Mice Following Transient Focal Cerebral Ischemia. Acta Cir Bras. 2017; 32(10): 862-872 . 5.Gao WW, He YH, Liu L, Yuan Q, Wang YF, Zhao B. BIS Monitoring on Intraoperative Awareness: A Meta-analysis. Curr Med Sci. 2018; 38(2): 349-353. 6.Gao WW, He ZG, Zhao B, Tang CL, Xiao Y, Jiang M, Xia ZY. Different concentrations of bupivacaine on postoperative urinary retention in patients undergoing subarachnoid anesthesia. Int J Clin Exp Med. 2017; 10(7): 10840-10845. 7.Gao W, Zhao B, Liu L, Yuan Q, Wu X, Xia Z. Myocardial ischemic post-conditioning protects the lung against myocardial ischemia/reperfusion-induced damage by activating GSK-3β. Acta Cir Bras. 2017; 32(5): 376-387.