武汉大学人民医院湖北省人民医院

院内导航

柯少波肿瘤
肿瘤Ⅳ科副主任，副主任医师，硕士生导师

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导师介绍

姓名	柯少波
出生年月	1982年2月
单位	武汉大学人民医院肿瘤中心
所属学科	临床医学-肿瘤学
职务、职称及头衔	肿瘤四科副主任，副主任医师，硕士生导师
E-mail	doctorhpyc@163.com, 416031678@qq.com
联系方式	027-88041911-81338,或 18702799859
研究方向	肿瘤靶向治疗，肿瘤免疫微环境调控
个人简介	主要从事消化系统肿瘤的精准治疗，主持及承担国家级、省级项目共5项。以第一/通讯作者发表SCI收录文章10余篇，其中Cell Death & Disease(9.685/Q1)、JAMA Network Open(13.353/Q1)，IJS(15.3/Q1)各1篇。多个研究成果在亚洲放疗联盟（FARO）、美国放射肿瘤学会年会( ASTRO)会议上口头报告交流。
学术任职与荣誉	湖北省抗癌协会鼻咽癌青委会副主委 ESCO食管癌专委会常委，湖北省医学生物免疫学会头颈肿瘤MDT副主委，湖北省抗癌协会理事，湖北省临床肿瘤学会精准放疗专家委员会委员湖北省抗癌协会鼻咽癌专委会委员，武大人民医院2021、2022、2023年医疗菁英
教育履历	2000/09–2005/07，湖北科技学院，临床医学，本科 2005/09–2007/07，武汉大学第一临床学院，外科学硕士 2012/09–2015/07，武汉大学第二临床学院，肿瘤学博士
工作履历	2007/07-2012/08,三峡大学附属仁和医院,主治医师 2015/07-2019/10，武大人民医院肿瘤中心，主治医师 2019年11月至今,武大人民医院肿瘤中心,副主任医师，后为科室副主任
成果获奖	无
代表性论著	(1) Xiangli Fan#,Jing Wang#,Lingling Xia,Hu Qiu,Yuanyuan Tian,Yutian Zhangcai,Xixi Luo,Yuelan Gao,Chen Li,Yong Wu,Wensi Zhao,Jiamei Chen,Wei Shi,Jingping Yuan,Shaobo Ke,Yongshun Chen. Efficacy of endoscopic therapy for T1b esophageal cancer and construction of prognosis prediction model: A retrospective cohort study. Int J Surg, 2023, 109(6):1708-1719.(IF: 15.3 /Q1)共同通讯. (2) Xue-Hua Du#,Shao-Bo Ke#, Xin-Yi Liang, Jie Gao, Xiao-Xiao Xie, Lin-Zhi Qi, Xue-Yi Liu, Guo-Yuan Xu, Xiao-Dong Zhang, Run-Lei Du, Shang-Ze Li. USP14 promotes colorectal cancer progression by targeting JNK for stabilization. Cell Death & Disease, 2023, 14(1):56.(IF: 9.696/Q1)共同第一作者. (3) Hu Qiu#,Shaobo Ke#, Gaoke Cai, Yong Wu, Jin Wang, Wei Shi, Jiamei Chen, Jin Peng, Baoping Yu, Yongshun Chen. An exploratory clinical trial of apatinib combined with intensity modulated radiation therapy for patients with unresectable hepatocellular Carcinoma. Cancer Medicine, 2023, 12(1):213-222. doi: 10.1002/cam4.4900.(IF: 4.711/Q2)共同第一作者. (4) Jiamei Chen#,Bo Luo#,Mengting Gao,Gaoke Cai,Xixi Luo,Yutian Zhang-Cai,Shaobo Ke, Yongshun Chen. Regional Lymph Node Metastasis and Axillary Surgery of Microinvasive Breast Cancer: A Population-Based Study. Diagnostics (Basel), 2022, 12(5):1049. doi: 10.3390/diagnostics12051049.(IF: 3.992/Q2)共同通讯 (5) Zhenguo Shi#, Xiaojuan Zhu#, Changli Ruan#, Gang Wei, Jiaojiao Li, Hu Qiu, Lijuan Gao, Gaoke Cai, Yutian Zhangcai, Bin Li, Jing Wang, Yi Gong, Jiamei Chen, Wensi Zhao, Yong Wu,Shaobo Ke, Yongshun Chen. Evaluation of Concurrent Chemoradiotherapy in Synchronous Oligometastatic Esophageal Squamous Cell Carcinoma. JAMA Network Open, 2022, 5(12):e2244619 .(IF: 13.360/Q1)共同通讯. (6) Jing Wang, Qiushuang Wang, Yi Gong, Hu Qiu,Shaobo Ke, Yongshun Chen. Knockdown of circRNA circ_0087378 represses the tumorigenesis and progression of esophageal squamous cell carcinoma through modulating the miR-140-3p/E2F3 axis, Frontiers in Oncology, 2020, 10: 607231. DOI:10.3389/fonc.2020. 607231.(IF: 6.244/Q2)共同通讯. (7)Shaobo Ke, Hu Qiu, Jia-mei Chen, Wei Shi, Chen Han, Yi Gong, Yong-shun Chen. ALG3 Contributes to the Malignancy of Non-small Cell Lung Cancer and Is Negatively Regulated by MiR-98-5p. Pathology Research and Practice. 2020 , 216(3):152761 .(IF: 3.309/Q2)第1作者. (8)Shao-bo Ke, Hu QIU, Jia-mei CHEN, Wei SHI, Yong-shun CHEN. Therapeutic Effect of First-line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor(EGFR-TKI)Combined with Whole Brain Radiotherapy in EGFR Mutation-positive Lung Adenocarcinoma Patients with Brain Metastases. Current Medical Science, 2018, 38(6):1062-1068.（IF:2.640/Q3 )第一作者. (9)Shaobo Ke,Fuxiang Zhou, Hui Yang, Yuehua Wei, Jun Gong, Zijie Mei, Lin Wu, Haijun Yu, Yunfeng Zhou. Downregulation of high mobility group box 1 modulates telomere homeostasis and increases the radiosensitivity of human breast cancer cells. International Journal of Oncology. 2015, 46(3):1051~1058.(IF: 5.884/Q2)第一作者.

Name	Shaobo ke
Date of birth	February, 1982
Department	Cancer center, Renmin Hospital of Wuhan University
Title	Deputy Director, Deputy chief physician, master tutor
Email	doctorhpyc@163.com, 416031678@qq.com
TEL	027-88041911-81338,或18702799859
Research Direction	Tumor targeted therapy, Tumor immune microenvironment regulation
Personal Profile	Mainly engaged in the precision treatment of digestive system tumors, presided over and undertook a total of 5 national and provincial projects. More than 10 SCI indexed articles were published as the first/corresponding author, including 1 each for Cell Death & Disease(9.685/Q1), JAMA Network Open(13.353/Q1) and IJS(15.3/Q1). Many of the findings were presented orally at the Federation of Asian Organizations for Radiation Oncology(FARO) and the American Society for Therapeutic Radiology and Oncology (ASTRO) annual meeting.
Selected Publications	(1) Xiangli Fan#,Jing Wang#,Lingling Xia,Hu Qiu,Yuanyuan Tian,Yutian Zhangcai,Xixi Luo,Yuelan Gao,Chen Li,Yong Wu,Wensi Zhao,Jiamei Chen,Wei Shi,Jingping Yuan,Shaobo Ke,Yongshun Chen. Efficacy of endoscopic therapy for T1b esophageal cancer and construction of prognosis prediction model: A retrospective cohort study. Int J Surg, 2023, 109(6):1708-1719.(IF: 15.3 /Q1) (2) Xue-Hua Du#,Shao-Bo Ke#, Xin-Yi Liang, Jie Gao, Xiao-Xiao Xie, Lin-Zhi Qi, Xue-Yi Liu, Guo-Yuan Xu, Xiao-Dong Zhang, Run-Lei Du, Shang-Ze Li. USP14 promotes colorectal cancer progression by targeting JNK for stabilization. Cell Death & Disease, 2023, 14(1):56 (IF: 9.696/Q1) (3) Hu Qiu#,Shaobo Ke#, Gaoke Cai, Yong Wu, Jin Wang, Wei Shi, Jiamei Chen, Jin Peng, Baoping Yu, Yongshun Chen. An exploratory clinical trial of apatinib combined with intensity modulated radiation therapy for patients with unresectable hepatocellular Carcinoma. Cancer Medicine, 2023, 12(1):213-222. doi: 10.1002/cam4.4900. (IF: 4.711/Q2) (4) Jiamei Chen#,Bo Luo#,Mengting Gao,Gaoke Cai,Xixi Luo,Yutian Zhang-Cai,Shaobo Ke, Yongshun Chen. Regional Lymph Node Metastasis and Axillary Surgery of Microinvasive Breast Cancer: A Population-Based Study. Diagnostics (Basel), 2022, 12(5):1049. doi: 10.3390/diagnostics12051049. (IF: 3.992/Q2) (5) Zhenguo Shi#, Xiaojuan Zhu#, Changli Ruan#, Gang Wei, Jiaojiao Li, Hu Qiu, Lijuan Gao, Gaoke Cai, Yutian Zhangcai, Bin Li, Jing Wang, Yi Gong, Jiamei Chen, Wensi Zhao, Yong Wu,Shaobo Ke, Yongshun Chen. Evaluation of Concurrent Chemoradiotherapy in Synchronous Oligometastatic Esophageal Squamous Cell Carcinoma. JAMA Network Open, 2022, 5(12):e2244619 . (IF: 13.360/Q1). (6) Jing Wang, Qiushuang Wang, Yi Gong, Hu Qiu,Shaobo Ke, Yongshun Chen. Knockdown of circRNA circ_0087378 represses the tumorigenesis and progression of esophageal squamous cell carcinoma through modulating the miR-140-3p/E2F3 axis, Frontiers in Oncology, 2020, 10: 607231. DOI:10.3389/fonc.2020. 607231. (IF: 6.244/Q2) (7)Shaobo Ke, Hu Qiu, Jia-mei Chen, Wei Shi, Chen Han, Yi Gong, Yong-shun Chen. ALG3 Contributes to the Malignancy of Non-small Cell Lung Cancer and Is Negatively Regulated by MiR-98-5p. Pathology Research and Practice. 2020 , 216(3):152761 . (IF: 3.309/Q2) (8)Shao-bo Ke, Hu QIU, Jia-mei CHEN, Wei SHI, Yong-shun CHEN. Therapeutic Effect of First-line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor(EGFR-TKI)Combined with Whole Brain Radiotherapy in EGFR Mutation-positive Lung Adenocarcinoma Patients with Brain Metastases. Current Medical Science, 2018, 38(6):1062-1068.（IF:2.640/Q3 ). (9)Shaobo Ke,Fuxiang Zhou, Hui Yang, Yuehua Wei, Jun Gong, Zijie Mei, Lin Wu, Haijun Yu, Yunfeng Zhou. Downregulation of high mobility group box 1 modulates telomere homeostasis and increases the radiosensitivity of human breast cancer cells. International Journal of Oncology. 2015, 46(3):1051~1058. (IF: 5.884/Q2).