武汉大学人民医院湖北省人民医院

院内导航

贺斌骨外
副主任医师，硕士生导师

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导师介绍

姓名	贺斌
出生年月	1983年2月
单位	武汉大学人民医院骨外科
所属学科	临床医学-外科学
职务、职称及头衔	副主任医师，硕士生导师
E-mail	hebin@whu.edu.cn
联系方式	027-88041911转82061或18120557820
研究方向	1.周围神经损伤再生修复 2.创伤性骨关节炎的研究
个人简介	主要从事创伤骨科的临床与科研工作，主持完成国家自然科学基金课题1项，参与国家自然科学基金课题5项、省级自然科学基金课题2项。以第一作者发表学术论文30余篇，其中SCI论文9篇。参编骨科专业著作《脊柱外科手术入路与技巧》
学术任职与荣誉	1. 中国医师协会显微外科医师分会委员 2. 亚太足踝外科医师协会中国区委员 3. 湖北省医学会手外科学分会委员 4. 湖北省中西医结合学会颈肩腰腿痛专业委员会委员 5. 湖北省预防医学会骨与关节病预防与控制专业委员会委员 6. 武汉医学会手外科分会委员 7. 武汉中西医结合学会骨伤专业委员会委员
教育履历	2002.09-2007.06武汉大学第一临床学院临床医学专业本科生获学士学位 2007.09-2009.06武汉大学第一临床学院外科学硕士研究生获硕士学位 2009.09-2012.06武汉大学第一临床学院外科学博士研究生获博士学位
工作履历	2012.07-2015.11 武汉大学人民医院骨外科主治医师 2018.12-2019.12 美国罗彻斯特大学访问学者 2015.11-至今武汉大学人民医院骨外科副主任医师
成果获奖	暂无
代表性论著	1．He B, Wu F, Li XH, Liu Y, Fan L, Li HH. Mitochondrial Dependent Pathway Is Involved in the Protective Effects of Carboxymethylated Chitosan on Nitric Oxide-Induced Apoptosis in Chondrocytes. BMC Complement Med Ther 2020; 20:23 2．He B, Wu F, Fan L, Li XH, Liu Y. Carboxymethylated chitosan promotes Schwann cell proliferation and expression of neurotrophic factors by activation of PKA and PKC signaling pathways. Int J Clin Exp Med 2019;12:220-229. 3．He B, Wu F, Fan L, Li XH, Liu Y, Liu YJ, Ding WJ, Deng M, Zhou Y. Carboxymethylated chitosan protects Schwann cells against hydrogen peroxide-induced apoptosis by inhibiting oxidative stress and mitochondria dependent pathway. European Journal of Pharmacology. 2018; 740:127-134. 4．He B, Tao HY, Liu SQ, Wei AL, Pan F, Chen R, Li XH. Carboxymethylated chitosan protects rat chondrocytes from NO-induced apoptosis via inhibition of the p38/MAPK signaling pathway. Molecular Medicine Reports, 2016; 13: 2151-2158. 5．He B, Tao HY, Wei AL, Liu SQ, Li XH, Chen R. Protection of carboxymethylated chitosan on chondrocytes from nitric oxide-induced apoptosis by regulating phosphatidylinositol 3-kinase/Akt signaling pathway. Biochemical and Biophysical Research Communications, 2016; 479:380-386. 6．He B, Tao HY, Liu SQ, Wei AL. Protective effect of carboxymethylated chitosan on hydrogen peroxide-induced apoptosis in nucleus pulposus cells. Molecular Medicine Reports, 2015; 11: 1629-1638. 7．He B, Tao HY, Liu SQ. Neuroprotective effects of carboxymethylated chitosan on hydrogen peroxide induced apoptosis in Schwann cells. European Journal of Pharmacology. 2014; 740:127-134. 8．Tao HY, He B, Liu SQ, Wei AL, Tao FH, Tao HL, Deng WX, Li HH, Chen Q. Effect of carboxymethylated chitosan on the biosynthesis of NGF and activation of the Wnt/β-catenin signaling pathway in the proliferation of Schwann cells. European Journal of Pharmacology. 2013; 702:85-92. 9．He B, Liu SQ, Chen Q, Li HH, Ding WJ, Deng M. Carboxymethylated chitosan stimulates proliferation of Schwann cells in vitro via the activation of the ERK and Akt signaling pathways. European Journal of Pharmacology. 2011; 667:195-201.

Name	BIN HE
Date of birth	Feb，1983
Department	Department of Orthopaedics，Renmin Hospital of Wuhan University.
Title	Associate chief physician, master's supervisor
Email	hebin@whu.edu.cn
TEL	027-88041911-82061 or 18120557820
Research Direction	1. Peripheral nerve injury and regeneration 2. Research of traumatic osteoarthritis
Personal Profile	He is mainly engaged in the clinical and research of tramatic disease in orthopaedics, and has awarded and finished 1 item of the National Natural Science Foundation, and participated 5 items from the National Natural Science Foundation and 2 items from provincial science and Technology Department. Besides, there are more than 30 articles published by the first author, including 9 SCI papers, and participated in the compilation of the orthopedic professional work "Spinal Surgery Approaches and Techniques.
Selected Publications	1．He B, Wu F, Li XH, Liu Y, Fan L, Li HH. Mitochondrial Dependent Pathway Is Involved in the Protective Effects of Carboxymethylated Chitosan on Nitric Oxide-Induced Apoptosis in Chondrocytes. BMC Complement Med Ther 2020; 20:23 2．He B, Wu F, Fan L, Li XH, Liu Y. Carboxymethylated chitosan promotes Schwann cell proliferation and expression of neurotrophic factors by activation of PKA and PKC signaling pathways. Int J Clin Exp Med 2019;12:220-229. 3．He B, Wu F, Fan L, Li XH, Liu Y, Liu YJ, Ding WJ, Deng M, Zhou Y. Carboxymethylated chitosan protects Schwann cells against hydrogen peroxide-induced apoptosis by inhibiting oxidative stress and mitochondria dependent pathway. European Journal of Pharmacology. 2018; 740:127-134. 4．He B, Tao HY, Liu SQ, Wei AL, Pan F, Chen R, Li XH. Carboxymethylated chitosan protects rat chondrocytes from NO-induced apoptosis via inhibition of the p38/MAPK signaling pathway. Molecular Medicine Reports, 2016; 13: 2151-2158. 5．He B, Tao HY, Wei AL, Liu SQ, Li XH, Chen R. Protection of carboxymethylated chitosan on chondrocytes from nitric oxide-induced apoptosis by regulating phosphatidylinositol 3-kinase/Akt signaling pathway. Biochemical and Biophysical Research Communications, 2016; 479:380-386. 6．He B, Tao HY, Liu SQ, Wei AL. Protective effect of carboxymethylated chitosan on hydrogen peroxide-induced apoptosis in nucleus pulposus cells. Molecular Medicine Reports, 2015; 11: 1629-1638. 7．He B, Tao HY, Liu SQ. Neuroprotective effects of carboxymethylated chitosan on hydrogen peroxide induced apoptosis in Schwann cells. European Journal of Pharmacology. 2014; 740:127-134. 8．Tao HY, He B, Liu SQ, Wei AL, Tao FH, Tao HL, Deng WX, Li HH, Chen Q. Effect of carboxymethylated chitosan on the biosynthesis of NGF and activation of the Wnt/β-catenin signaling pathway in the proliferation of Schwann cells. European Journal of Pharmacology. 2013; 702:85-92. 9．He B, Liu SQ, Chen Q, Li HH, Ding WJ, Deng M. Carboxymethylated chitosan stimulates proliferation of Schwann cells in vitro via the activation of the ERK and Akt signaling pathways. European Journal of Pharmacology. 2011; 667:195-201.