周晓亚
心内
心内II科副主任，主任医师，副教授，硕士生导师
心内II科副主任，主任医师，副教授，硕士生导师
导师介绍
| 姓名 | 周晓亚 |
| 出生年月 | 1980年6月 |
| 单位 | 武汉大学人民医院心血管内科 |
| 所属学科 | 临床医学-内科学 |
| 职务、职称及头衔 | 心内II科副主任，主任医师，副教授，硕士生导师 |
| whuzhouxiaoya@163.com | |
| 联系方式 | 15872355240 |
| 研究方向 |
1.自主神经与心血管疾病 2.肿瘤心脏病学 3.心电生理与心律失常 |
| 个人简介 | 主要从事心血管疾病的诊治与科研工作。主持国家自然科学基金等科研项目4项，作为骨干参与国家重点研发计划、国家自然科学基金重点项目等科研项目10余项，以第一/通讯作者（含共同）在Cardiovasc Res、EBioMedicine、Advanced Science等国际知名期刊发表创新研究30余篇。协助培养博士生10余名，硕士生10余名，目前正培养硕士生3名。协助指导学生发表高质量创新研究20余篇，研究生获国家奖学金3人次，中华医学会心血管青年医师英语演讲比赛一等奖等奖励。 |
| 学术任职与荣誉 | 中国生物医学工程学会心律分会女性心律失常组委员 |
| 教育履历 |
1997.09-2002.06中国人民武装警察部队医学院，临床医学，本科 2008.09-2010.06武汉大学第一临床学院，内科学，硕士 2010.09-2013.06武汉大学第一临床学院，内科学，博士 |
| 工作履历 |
2002.08-2006.06,海南省武警总队医院,内科,医师 2006.07-2007.06,俄罗斯谢东诺夫医学院,医疗系,访问学者 2013.08-2013.12,武汉大学人民医院,心血管内科,医师 2014.01-2015.11,武汉大学人民医院,心血管内科,主治医师 2015.12-2021.11,武汉大学人民医院,心血管内科,副主任医师 2016.09-2017.09,美国加利福尼亚大学洛杉矶分校（UCLA）,David Geffen School of Medicine,访问学者 2018.12-今，武汉大学人民医院,心血管内科,副教授 2021.12-今，武汉大学人民医院，心血管内科，主任医师 2022.06-今，武汉大学人民医院，心血管内科，心内II科副主任 |
| 成果获奖 |
1.2022年湖北省科技进步一等奖 2.2018年湖北省科技进步一等奖 3.2021年中华医学科技奖 |
| 代表性论著 |
1.
Zhou L（#）, Zhang Y（#）, Cao
G, Zhang C, Zheng C, Meng G, Lai Y, Zhou Z, Liu Z, Liu Z, Guo F, Dong X,
Liang Z, Wang Y, Guo S, Zhou X（*）, Jiang
H（*）, Yu L（*）.
Wireless Self-Powered Optogenetic System for Long-Term Cardiac
Neuromodulation to Improve Post-MI Cardiac Remodeling and Malignant
Arrhythmia. Adv Sci (Weinh). 2023 Mar;10(9):e2205551.（IF: 15.1） 2. Meng G（#）, Zhou X（#）, Wang M, Zhou L, Wang Z, Wang M, Deng J, Wang Y, Zhou Z, Zhang Y, Lai Y, Zhang Q, Yang X, Yu L（*）, Jiang H（*）. Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways. EBioMedicine. 2019 Jun;44:656-664.（IF=11.1） 3. Lai Y（#）, Zhou X（#）, Guo F（#）, Jin X, Meng G, Zhou L, Chen H, Liu Z, Yu L（*）, Jiang H（*）. Non-invasive transcutaneous vagal nerve stimulation improves myocardial performance in doxorubicin-induced cardiotoxicity. Cardiovasc Res. 2022 Jun 22;118(7):1821-1834.（IF=10.8） 4. Lai Y（#）, Deng J（#）, Wang M, Wang M, Zhou L, Meng G, Zhou Z, Wang Y, Guo F, Yin M, Zhou X（*）, Jiang H（*）. Vagus nerve stimulation protects against acute liver injury induced by renal ischemia reperfusion via antioxidant stress and anti-inflammation. Biomed Pharmacother. 2019 Sep;117:109062.（IF=7.5） 5. Liu Z（#）, Liu Z（#）, Zhou H（#）, Zhou Y, Xu X, Li Z, Guo F, Wang Y, Zhou Z, Zhou L, Wang Y, Zhou X（*）, Xia H（*）, Jiang H（*）. Increased sympathetic outflow induced by emotional stress aggravates myocardial ischemia-reperfusion injury via activation of TLR7/MyD88/IRF5 signaling pathway. Inflamm Res. 2023 May;72(5):901-913.（IF=6.7） 6. Jin X（#）, Wang X（#）, Sun J（#）, Tan W, Zhang G, Han J, Xie M, Zhou L, Yu Z, Xu T, Wang C, Wang Y（*）, Zhou X（*）, Jiang H（*）. Subthreshold splenic nerve stimulation prevents myocardial Ischemia-Reperfusion injury via neuroimmunomodulation of proinflammatory factor levels. Int Immunopharmacol. 2023 Jan;114:109522.（IF: 5.6） 7.Wang S（#）, Zhou X（#）Huang B, Wang Z, Zhou L, Chen M, Yu L（*）, Jiang H（*）. Spinal cord stimulation suppresses atrial fibrillation by inhibiting autonomic remodeling. Heart Rhythm. 2016 Jan;13(1):274-81.（IF=5.5） 8. Wang S, Zhou X*, Huang B, Wang Z, Liao K, Saren G, Lu Z, Chen M, Yu L（*）, Jiang H. Sp（*）inal cord stimulation protects against ventricular arrhythmias by suppressing left stellate ganglion neural activity in an acute myocardial infarction canine model. Heart Rhythm. 2015 Jul;12(7):1628-35.（IF=5.5） 9. Yu L（#）, Huang B（#）, Wang Z, Wang S, Wang M, Li X, Zhou L, Meng G, Yuan S, Zhou X（*）, Jiang H（*）. Impacts of Renal Sympathetic Activation on Atrial Fibrillation: The Potential Role of the Autonomic Cross Talk Between Kidney and Heart. J Am Heart Assoc. 2017 Mar 2;6(3):e004716.（IF=5.4） 10. Hu X（#）, Zhou X（#）, He B, Xu C, Wu L, Cui B, Wen H, Lu Z, Jiang H（*）. Minocycline protects against myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein in rats. Eur J Pharmacol. 2010 Jul 25;638(1-3):84-9.（IF=5.0） |
| Name | XIAO YA ZHOU |
| Date of birth | June，1980 |
| Department | Cardiovascular Department, Renmin Hospital,Wuhan University. |
| Title | Vice Director of Cardiology Ward II, Chief Physician, Associate Professor, Master Tutor |
| whuzhouxiaoya@163.com | |
| TEL | 15872355240 |
| Research Direction |
1.Autonomic
nerve system and cardiovascular diseases 2. Cardio-Oncology 3. Cardiac electrophysiology and arrhythmia |
| Personal Profile | Professor Xiaoya Zhou engages in the diagnosis, treatment and scientific research of cardiovascular diseases. She is the project director of four scientific research projects including the National Natural Science Foundation of China. As the backbone of the team, she also participated in more than 10 projects such as the National Key R&D Program and the Key Program of the National Natural Science Foundation of China. As the first/corresponding author (including co-author)，she published more than 30 innovative articles in the journal Cardiovasc Res, EBioMedicine and other leading international journals. She has assisted in training more than 10 doctoral students and more than 10 master students, and is currently training 3 master students. She assisted and guided students to publish more than 20 innovative papers. Postgraduates have won the National Scholarships three times, the first prize of the Chinese Medical Association Young Cardiovascular Physician English Speech Contest and other awards. |
| Selected Publications |
1.
Zhou L（#）, Zhang Y（#）, Cao
G, Zhang C, Zheng C, Meng G, Lai Y, Zhou Z, Liu Z, Liu Z, Guo F, Dong X,
Liang Z, Wang Y, Guo S, Zhou X（*）, Jiang
H（*）, Yu L（*）.
Wireless Self-Powered Optogenetic System for Long-Term Cardiac
Neuromodulation to Improve Post-MI Cardiac Remodeling and Malignant
Arrhythmia. Adv Sci (Weinh). 2023 Mar;10(9):e2205551.（IF: 15.1） 2. Meng G（#）, Zhou X（#）, Wang M, Zhou L, Wang Z, Wang M, Deng J, Wang Y, Zhou Z, Zhang Y, Lai Y, Zhang Q, Yang X, Yu L（*）, Jiang H（*）. Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways. EBioMedicine. 2019 Jun;44:656-664.（IF=11.1） 3. Lai Y（#）, Zhou X（#）, Guo F（#）, Jin X, Meng G, Zhou L, Chen H, Liu Z, Yu L（*）, Jiang H（*）. Non-invasive transcutaneous vagal nerve stimulation improves myocardial performance in doxorubicin-induced cardiotoxicity. Cardiovasc Res. 2022 Jun 22;118(7):1821-1834.（IF=10.8） 4. Lai Y（#）, Deng J（#）, Wang M, Wang M, Zhou L, Meng G, Zhou Z, Wang Y, Guo F, Yin M, Zhou X（*）, Jiang H（*）. Vagus nerve stimulation protects against acute liver injury induced by renal ischemia reperfusion via antioxidant stress and anti-inflammation. Biomed Pharmacother. 2019 Sep;117:109062.（IF=7.5） 5. Liu Z（#）, Liu Z（#）, Zhou H（#）, Zhou Y, Xu X, Li Z, Guo F, Wang Y, Zhou Z, Zhou L, Wang Y, Zhou X（*）, Xia H（*）, Jiang H（*）. Increased sympathetic outflow induced by emotional stress aggravates myocardial ischemia-reperfusion injury via activation of TLR7/MyD88/IRF5 signaling pathway. Inflamm Res. 2023 May;72(5):901-913.（IF=6.7） 6. Jin X（#）, Wang X（#）, Sun J（#）, Tan W, Zhang G, Han J, Xie M, Zhou L, Yu Z, Xu T, Wang C, Wang Y（*）, Zhou X（*）, Jiang H（*）. Subthreshold splenic nerve stimulation prevents myocardial Ischemia-Reperfusion injury via neuroimmunomodulation of proinflammatory factor levels. Int Immunopharmacol. 2023 Jan;114:109522.（IF: 5.6） 7.Wang S（#）, Zhou X（#）Huang B, Wang Z, Zhou L, Chen M, Yu L（*）, Jiang H（*）. Spinal cord stimulation suppresses atrial fibrillation by inhibiting autonomic remodeling. Heart Rhythm. 2016 Jan;13(1):274-81.（IF=5.5） 8. Wang S, Zhou X*, Huang B, Wang Z, Liao K, Saren G, Lu Z, Chen M, Yu L（*）, Jiang H. Sp（*）inal cord stimulation protects against ventricular arrhythmias by suppressing left stellate ganglion neural activity in an acute myocardial infarction canine model. Heart Rhythm. 2015 Jul;12(7):1628-35.（IF=5.5） 9. Yu L（#）, Huang B（#）, Wang Z, Wang S, Wang M, Li X, Zhou L, Meng G, Yuan S, Zhou X（*）, Jiang H（*）. Impacts of Renal Sympathetic Activation on Atrial Fibrillation: The Potential Role of the Autonomic Cross Talk Between Kidney and Heart. J Am Heart Assoc. 2017 Mar 2;6(3):e004716.（IF=5.4） 10. Hu X（#）, Zhou X（#）, He B, Xu C, Wu L, Cui B, Wen H, Lu Z, Jiang H（*）. Minocycline protects against myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein in rats. Eur J Pharmacol. 2010 Jul 25;638(1-3):84-9.（IF=5.0） |
武汉大学人民医院
湖北省人民医院