武汉大学人民医院湖北省人民医院

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阎红琳 临床病理学
研究生教学秘书，科研秘书，副教授，副主任技师，硕士生导师

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导师介绍

姓名	阎红琳
出生年月	1988年10月
单位	武汉大学人民医院病理科
所属学科	临床病理学
职务、职称及头衔	研究生教学秘书，科研秘书，副教授，副主任技师，硕士生导师
E-mail	honglin@whu.edu.cn
联系方式	027-88041911转85523
研究方向	1.肿瘤新辅助化疗疗效预测标记物的研究 2.肿瘤微环境研究 3.神经系统疾病发病机制研究
个人简介	主要从事乳腺癌肿瘤微环境、新辅助化疗疗效预测标记物及神经系统疾病发病机制研究工作，主持国家自然科学基金1项、湖北省自然科学基金1项、中央高校基本科研业务费专项资金1项，参与国家级、省市级科研项目8项。参编专著2部，以第一作者/通讯作者在Stroke、Cell Death & Disease、Int J Biol Sci等杂志上发表论文30余篇，其中SCI论文10篇（中科院二区以上论文5篇，单篇最高引用159次）。曾获湖北省科技进步三等奖1项、湖北省高等学校教学成果奖三等奖1项、武汉大学教学成果二等奖1项。
学术任职与荣誉	中华医学会病理学分会病理技术学组青年骨干；中国研究型医院学会分子诊断医学专业委员会青年委员；中国抗癌协会肿瘤病理专委会大数据学组组员；中国医疗保健国际交流促进会病理学分会委员；湖北省医学会病理学分会第九届委员会病理技术学组组员；湖北省病理科医疗质量控制中心病理技术学组专家组成员；湖北省抗癌协会肿瘤病理专业委员会委员；湖北省临床肿瘤学会肿瘤病理专家委员会委员；湖北省临床肿瘤学会（ESCO）健康教育专家委员会委员；临床与实验病理学杂志青年编委；中国组织化学与细胞化学杂志编委。
教育履历	2011.09 - 2015.06：华中科技大学同济医学院病理学与病理生理学硕博连读（1+3）研究生获博士学位 2007.09 - 2011.06：河南工业大学生物制药专业本科生获学士学位
工作履历	2022/12 -至今武汉大学人民医院，病理科，副教授，副主任技师 2017/12 -至今武汉大学人民医院，病理科，副主任技师 2015/12 - 2017/11武汉大学人民医院，病理科，主管技师 2015/07 - 2015/11武汉大学人民医院，病理科，技师
成果获奖	1.《“四严四会”，卓越病理医师培养的探索与实践》2022年获湖北省高等学校教学成果三等奖 2.《肿瘤微环境研究及其在乳腺癌预后预测中的应用》2021年获湖北省科技进步三等奖 3.《“四严四会”培养病理卓越医生的探索与实践》2021年获武汉大学教学成果二等奖
代表性论著	1.Honglin Yan#, Jie Rao#, Jingping Yuan, Likun Gao, Wenxian Huang, Lina Zhao, Jiacai Ren, Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate ischemic neuronal death by targeting miR-21/PDCD4 signaling pathway, Cell Death Dis, 2017, 8(12): 3211.一区Top 2.Xiaoxi Wang#, Lei Pei#,Honglin Yan#, Zhongping Wang, Na Wei, Shan Wang, Xin Yang, Qing Tian, Youming Lu, Intervention of death-associated protein kinase 1-p53 interaction exerts the therapeutic effects against stroke, Stroke, 2014, 45(10): 3089-3091.一区Top 3.Honglin Yan, Bin Luo, Xiaoyan Wu, Feng Guan, Xinxin Yu, Lina Zhao, Xiaokang Ke, Juan Wu, Jingping Yuan. Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer. Int J Biol Sci, 2021, 17(10): 2606-2621.二区 4.Jingping Yuan, Huihua He, Chuang Chen, Juan Wu, Jie Rao,Honglin Yan. Combined high expression of CD47 and CD68 is a novel prognostic factor for breast cancer patients. Cancer Cell International, 2019, 19: 238.二区 5.Honglin Yan, Wenxian Huang, Jie Rao, Jingping Yuan. miR-21 regulates ischemic neuronal injury via the p53/Bcl-2/Bax signaling pathway. Aging (Albany NY). 2021, 13(18):22242-22255.二区

Name	Honglin Yan
Date of birth	October，1988
Department	Department of Pathology, Renmin Hospital, Wuhan University.
Title	Graduate Teaching Secretary, Scientific Research Secretary, Associate Professor, Associate Chief Technician, Master Tutor
Email	honglin@whu.edu.cn
TEL	027-88041911-85523
Research Direction	1. Tumor neoadjuvant chemotherapy efficacy prediction markers 2. Tumor microenvironment 3. Pathogenesis of nervous system diseases
Personal Profile	She is mainly engaged in the research of breast cancer tumor microenvironment, predictive markers of neoadjuvant chemotherapy efficacy and the pathogenesis of nervous system diseases. She has presided over one National Natural Science Foundation of China, one Natural Science Foundation of Hubei Province, one Fundamental Research Funds for the Central Universities, and participated in eight other scientific research projects. She has co-edited 2 monographs and published more than 30 papers as the first author/corresponding author inStroke, Cell Death & Disease, Int J Biol Sciand other journals, including 10 SCI papers (5 papers above the second district of Chinese Academy of Sciences, with a maximum citation of 159 times per single paper). She has won one third prize of Hubei Provincial Science and Technology Progress Award, one third prize of Hubei Provincial Higher Education Teaching Achievement Award and one second prize of Wuhan University Teaching Achievement Award.
Selected Publications	1.Honglin Yan#, Jie Rao#, Jingping Yuan, Likun Gao, Wenxian Huang, Lina Zhao, Jiacai Ren, Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate ischemic neuronal death by targeting miR-21/PDCD4 signaling pathway, Cell Death Dis, 2017, 8(12): 3211.一区Top 2.Xiaoxi Wang#, Lei Pei#,Honglin Yan#, Zhongping Wang, Na Wei, Shan Wang, Xin Yang, Qing Tian, Youming Lu, Intervention of death-associated protein kinase 1-p53 interaction exerts the therapeutic effects against stroke, Stroke, 2014, 45(10): 3089-3091.一区Top 3.Honglin Yan, Bin Luo, Xiaoyan Wu, Feng Guan, Xinxin Yu, Lina Zhao, Xiaokang Ke, Juan Wu, Jingping Yuan. Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer. Int J Biol Sci, 2021, 17(10): 2606-2621.二区 4.Jingping Yuan, Huihua He, Chuang Chen, Juan Wu, Jie Rao,Honglin Yan. Combined high expression of CD47 and CD68 is a novel prognostic factor for breast cancer patients. Cancer Cell International, 2019, 19: 238.二区 5.Honglin Yan, Wenxian Huang, Jie Rao, Jingping Yuan. miR-21 regulates ischemic neuronal injury via the p53/Bcl-2/Bax signaling pathway. Aging (Albany NY). 2021, 13(18):22242-22255.二区