杨波
心内
心血管内科副主任兼心内Ⅱ科主任、教授、主任医师、博士生导师、武汉大学人民医院首届医疗名家
心血管内科副主任兼心内Ⅱ科主任、教授、主任医师、博士生导师、武汉大学人民医院首届医疗名家
导师介绍
| 姓名 | 杨波 |
| 出生年月 | 1963年11月 |
| 单位 | 武汉大学人民医院心血管内科 |
| 所属学科 | 临床医学-内科学 |
| 职务、职称及头衔 | 心血管内科副主任兼心内Ⅱ科主任、教授、主任医师、博士生导师、武汉大学人民医院首届医疗名家 |
| yybb112@whu.edu.cn | |
| 联系方式 | 027-88041911转81037 |
| 研究方向 |
1.心律失常发生机制与临床治疗 2.介入心脏病学 |
| 个人简介 | 长期从事心血管疾病的临床、科研和教学工作，曾赴美国、意大利研修心血管疾病的防治。获国家科技进步二等奖1项，湖北省科技进步一等奖4项、湖北省科技成果推广一等奖1项，湖北省及教育部科技进步二等奖各1项，武汉市科技进步一、二等奖各1项。主编学术专著7部，参编学术专著20余部，发表学术论文200余篇，其中以通讯作者发表41篇SCI论文，1区2篇（发表在《JAMA Cardiology》的论文被引用高达两千多次），2区9篇。主持国家及部级课题2项，省级课题3项，校级项目1项，临床研究课题5项。近20年已培养博士生17名，硕士生55名。目前正在培养的研究生15名。 |
| 学术任职与荣誉 |
中华医学会心电生理和起搏分会第五、六、七届委员会委员 中华医学会心血管病分会第十届委员会心律失常学组副组长 中国卒中学会心血管病分会委员 中国心电信息学分会第四、五届委员会副主任委员 中华医学会心电生理和起搏分会暨中国医师协会心律学专业委员会中青年电生理工作委员会指导委员会委员 中国房颤中心联盟专家委员会常务委员 湖北省医学会心电生理与起搏分会常务委员 湖北省康复医学会心血管康复专业委员会副主任委员 湖北省医学会胸心外科分会结构性心脏病学组副组长 湖北省闭塞病变介入俱乐部专家委员会委员 湖北省房颤中心专家委员会委员 湖北省中西医结合学会脑心同治专业委员会副主任委员 湖北省基层卫生协会社区卫生服务机构联合体专家 湖北省心血管病介入诊疗技术质控中心秘书 国家卫健委心血管疾病介入诊疗技术培训项目培训基地（冠心病介入、心律失常介入）导师 《中国心脏起搏与心电生理杂志》编委 《聚焦高血压杂志》编委 《临床内科杂志》编委 《中华老年多器官衰竭杂志》编委 《武汉大学学报医学版》审稿专家 国家、湖北省暨武汉市医疗事故鉴定委员会专家 湖北省省劳动人事厅工伤及劳动能力鉴定委员会专家 |
| 教育履历 |
1981.09-1986.07 同济医科大学医学系本科生获学士学位 1993.09-1998.07 湖北医科大学内科学研究生硕、博连读获博士学位 1999年和2001年 先后赴意大利、美国进修心律失常的诊断和治疗技术 |
| 工作履历 |
1986.07-1993.07 湖北省梨园医院住院医师、主治医师 1998.07-2001.12 湖北省人民医院心内科 副主任医师、副教授 2001.12-2009.07 武汉大学人民医院心内科主任医师、教授、硕士生导师 2009.07-至今 武汉大学人民医院心内科主任医师、教授、博士生导师 |
| 成果获奖 |
1.《心房颤动的防治策略研究与推广应用》2014年湖北省科技成果推广奖一等奖 2.《心肌重构的发病基础与临床防治》2014年湖北省科技进步奖一等奖 3.《快速性心律失常的基础与临床研究》2011年华夏科技奖一等奖 4.《经导管消融治疗房室结折返性心动过速的术式优化》2008年武汉市科技进步奖二等奖 5.《心房结构与房性心律失常关系的基础与临床研究》2007年教育部科学技术进步奖二等奖 6.《心房结构与房性心律失常关系的基础与临床研究》2007年湖北省科技进步一等奖 7.《心房结构与房性心律失常关系的基础与临床研究》2007年武汉市科技进步奖一等奖 8.《心房颤动的基础与临床研究》2003年湖北省科技进步奖一等奖 9.《房室结折返性心动过速的发病基础及射频消融》2001年国家科学技术进步奖二等奖 10.《难治性心律失常的介入治疗》2000年湖北省科技成果推广奖一等奖 11.《房室结交界区组织学结构、电生理特点及与房室结双径的关系研究》2000年湖北省科技进步奖一等奖 |
| 代表性论著 |
1. Xiuhuan Chen,
Weiguo Wan, Yan Guo, Tianxin Ye, Yuhong Fo,
Yazhou Sun, Chuan Qu, Bo Yang and Cui Zhang, Pinocembrin
ameliorates post‑infarct heart failure through activation
of Nrf2/HO‑1 signaling pathway, Mol Med., 2021 Sep 6;27(1):100. 2. Chuang Li, Weiguo Wan, Tianxin Ye, Yazhou Sun, Xiaoli Chen, Xin Liu, Shaobo Shi, Yan Zhang, Chuan Qu, Bo Yang*, Cui Zhang*，Pinocembrin alleviates lipopolysaccharide-induced myocardial injury and cardiac dysfunction in rats by inhibiting p38/JNK MAPK pathway, Life Sci, 2021, 277:119418. 3. Yan Guo, Cui Zhang, Tianxin Ye, Xiuhuan Chen, Xin Liua, Xiaoli Chen, Yazhou Sun, Chuan Qu, Jinjun Liang, Shaobo Shi and Bo Yanga, Pinocembrin ameliorates arrhythmias in rats with chronic ischaemic heart failure, Annals of Medicine, 2021, 53(1):830-840. 4.Yan Guo, Cui Zhang, Xiuhuan Chen, Xin Liu, Tianxin Ye, Yuhong Fo, Shaobo Shi, Chuan Qu, Jinjun Liang, Bo Shen, Bo Yang, Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder, Psychopharmacology (Berl), 2021, 238: 487-499.1. 5. Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, Gong W, Liu X, Liang J, Zhao Q, Huang H, Yang B and Huang C. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5:802-810. 6. Shi S, Qin M, Cai Y, Liu T, Shen B, Yang F, Cao S, Liu X, Xiang Y, Zhao Q, Huang H, Yang B and Huang C. Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019. Eur Heart J. 2020;41:2070-2079. 7. Ye T, Zhang C, Wu G, Wan W, Guo Y, Fo Y, Chen X, Liu X, Ran Q, Liang J, Shi S and Yang B. Pinocembrin Decreases Ventricular Fibrillation Susceptibility in a Rat Model of Depression. Front Pharmacol. 2020;11:547966. 8. Liu X, Qu C, Shi S, Ye T, Wang L, Liu S, Zhang C, Liang J, Hu D and Yang B. The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism. Front Physiol. 2019;10:1346. 9. Liu X, Qu C, Yang H, Shi S, Zhang C, Zhang Y, Liang J and Yang B. Chronic stimulation of the sigma-1 receptor ameliorates autonomic nerve dysfunction and atrial fibrillation susceptibility in a rat model of depression. Am J Physiol Heart Circ Physiol. 2018;315:H1521-H1531. 10. Liu X, Shi S, Yang H, Qu C, Chen Y, Liang J and Yang B. The activation of N-methyl-d-aspartate receptors downregulates transient outward potassium and L-type calcium currents in rat models of depression. Am J Physiol Cell Physiol. 2017;313:C187-C196. 11. Shi S, Liu T, Wang D, Zhang Y, Liang J, Yang B and Hu D. Activation of N-methyl-d-aspartate receptors reduces heart rate variability and facilitates atrial fibrillation in rats. Europace. 2017;19:1237-1243. 12. Shi S, Liu T, Liang J, Hu D and Yang B. Depression and Risk of Sudden Cardiac Death and Arrhythmias: A Meta-Analysis. Psychosom Med. 2017;79:153-161. 13. Yang B, Yang J, Bai J, Pu P, Liu J, Wang F and Ruan B. Suv39h1 protects from myocardial ischemia-reperfusion injury in diabetic rats. Cell Physiol Biochem. 2014;33:1176-85. 14. Fo Y, Zhang C, Chen X, Liu X, Ye T, Guo Y, Qu C, Shi S and Yang B. Chronic sigma-1 receptor activation ameliorates ventricular remodeling and decreases susceptibility to ventricular arrhythmias after myocardial infarction in rats. Eur J Pharmacol. 2020;889:173614. 15. Chen X, Zhang C, Guo Y, Liu X, Ye T, Fo Y, Qu C, Liang J, Shi S and Yang B. Chronic stimulation of the sigma-1 receptor ameliorates ventricular ionic and structural remodeling in a rodent model of depression. Life Sciences. 2020;257. 16. Gao Q, Dai Z, Hu Y, Bie F and Yang B. A new method to determine the QRS axis-QRS axis determination. Clin Cardiol. 2020;43:1534-1538. 17. Guo Y, Zhang C, Chen X, Liu X, Ye T, Fo Y, Shi S, Qu C, Liang J, Shen B and Yang B. Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder. Psychopharmacology (Berl). 2020. 18. Qu C, Liu X, Guo Y, Fo Y, Chen X, Zhou J and Yang B. MiR-128-3p inhibits vascular smooth muscle cell proliferation and migration by repressing FOXO4/MMP9 signaling pathway. Mol Med. 2020;26:116. 19. Li PF, He RH, Shi SB, Li R, Wang QT, Rao GT and Yang B. Modulation of miR-10a-mediated TGF-beta1/Smads signaling affects atrial fibrillation-induced cardiac fibrosis and cardiac fibroblast proliferation. Biosci Rep. 2019;39. 20. Ye T, Liu X, Qu C, Zhang C, Fo Y, Guo Y, Chen X, Shi S and Yang B. Chronic inhibition of the sigma-1 receptor exacerbates atrial fibrillation susceptibility in rats by promoting atrial remodeling. Life Sci. 2019;235:116837. |
| Name | BO YANG |
| Date of birth | 14-Nov-63 |
| Department | Cardiovascular Department，Renmin Hospital,Wuhan University. |
| Title | Director, Professor, doctoral tutor |
| yybb112@whu.edu.cn | |
| TEL | 027-88041911-81037 |
| Research Direction |
1.
Mechanism and clinical treatment of arrhythmia 2. Interventional cardiology |
| Personal Profile |
Bo Yang ,MD, PHD, professor of medicine, doctoral supervisor. He’s major focus is the identification of diagnosis, treatment and scientific research of cardiovascular diseases. He has presided over 2 national and ministerial project, 4 provincial projects, 1 university-level project and 5 clinical research projects. He is the chief editor of 6 academic monographs, the editorial board member of "Chinese Journal of Cardiac Pace and Electrophysiology", and the reviewer of "Chinese Journal of Geriatric Multiple Organs Failure", "Journal of Wuhan University Medical Edition" and other journals. As the corresponding author, he published 41 SCI papers, including 2 in section 1 (the papers published in JAMA Cardiology were cited over 2000 times) and 9 in section 2. In addition, he has published over 200 papers in Chinese core journals. Bo Yang has trained 17 doctoral students and 55 master's students.Currently, there are 15 students. Professional Affiliations: Vice chairman of Chinese ECG Informatics Branch Committee member of arrhythmia drug therapy group of electrophysiology and pacing branch of Chinese medical association Member of the Working Committee of Heart Failure Device Therapy, Chinese Association of Electrophysiology and Pacing Member of atrial fibrillation working committee of electrophysiology and pacing branch of Chinese medical association Member of the Ventricular Arrhythmia Working Committee of the Chinese Association of Electrophysiology and Ppacing Member of the Steering Committee of the Young and Middle-aged Electrophysiological Working Committee of the Cardiology Professional Committee of the Chinese Medical Doctor Association, Chinese Medical Association Electrophysiology and Ppacing Branch Member of Arrhythmia Drug Therapy Committee, Chinese Society of Biomedical Engineering Member of the Working Committee of VENTRICULAR ARRHYTHMIA AND SUDDEN DEATH, Chinese Society of Biomedical Engineering Standing member of Hubei Medical Association ECG Electrophysiology and Pace Branch Hubei Provincial Association of Rehabilitation Cardiovascular Rehabilitation Professional Committee Vice Chairman Deputy leader of structural cardiology group of thoracic and cardiac surgery branch of Hubei Medical Association Member of Expert Committee of Hubei Obstructive Lesion Intervention Club Member of atrial fibrillation center expert committee of hubei province Hubei integrated traditional Chinese and western medicine society brain heart tongzhi professional committee vice-chairman Standing member of the first expert committee of China atrial fibrillation center alliance Standing Member of the First Committee of China Alliance of Atrial Fibrillation Centers Editorial board member of Chinese Journal of Cardiac Pace and Electrophysiology Reviewer of Chinese Journal of Geriatric Multiple Organ Failure Reviewer of Journal of Medical Science of Wuhan University |
| Selected Publications |
1. Xiuhuan Chen, Weiguo Wan, Yan Guo,
Tianxin Ye, Yuhong Fo, Yazhou Sun, Chuan Qu, Bo Yang
and Cui Zhang, Pinocembrin ameliorates post‑infarct heart failure
through activation of Nrf2/HO‑1 signaling pathway, Mol Med., 2021
Sep 6;27(1):100. 2. Chuang Li, Weiguo Wan, Tianxin Ye, Yazhou Sun, Xiaoli Chen, Xin Liu, Shaobo Shi, Yan Zhang, Chuan Qu, Bo Yang*, Cui Zhang*，Pinocembrin alleviates lipopolysaccharide-induced myocardial injury and cardiac dysfunction in rats by inhibiting p38/JNK MAPK pathway, Life Sci, 2021, 277:119418. 3. Yan Guo, Cui Zhang, Tianxin Ye, Xiuhuan Chen, Xin Liua, Xiaoli Chen, Yazhou Sun, Chuan Qu, Jinjun Liang, Shaobo Shi and Bo Yanga, Pinocembrin ameliorates arrhythmias in rats with chronic ischaemic heart failure, Annals of Medicine, 2021, 53(1):830-840. 4.Yan Guo, Cui Zhang, Xiuhuan Chen, Xin Liu, Tianxin Ye, Yuhong Fo, Shaobo Shi, Chuan Qu, Jinjun Liang, Bo Shen, Bo Yang, Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder, Psychopharmacology (Berl), 2021, 238: 487-499.1. 5. Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, Gong W, Liu X, Liang J, Zhao Q, Huang H, Yang B and Huang C. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5:802-810. 6. Shi S, Qin M, Cai Y, Liu T, Shen B, Yang F, Cao S, Liu X, Xiang Y, Zhao Q, Huang H, Yang B and Huang C. Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019. Eur Heart J. 2020;41:2070-2079. 7. Ye T, Zhang C, Wu G, Wan W, Guo Y, Fo Y, Chen X, Liu X, Ran Q, Liang J, Shi S and Yang B. Pinocembrin Decreases Ventricular Fibrillation Susceptibility in a Rat Model of Depression. Front Pharmacol. 2020;11:547966. 8. Liu X, Qu C, Shi S, Ye T, Wang L, Liu S, Zhang C, Liang J, Hu D and Yang B. The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism. Front Physiol. 2019;10:1346. 9. Liu X, Qu C, Yang H, Shi S, Zhang C, Zhang Y, Liang J and Yang B. Chronic stimulation of the sigma-1 receptor ameliorates autonomic nerve dysfunction and atrial fibrillation susceptibility in a rat model of depression. Am J Physiol Heart Circ Physiol. 2018;315:H1521-H1531. 10. Liu X, Shi S, Yang H, Qu C, Chen Y, Liang J and Yang B. The activation of N-methyl-d-aspartate receptors downregulates transient outward potassium and L-type calcium currents in rat models of depression. Am J Physiol Cell Physiol. 2017;313:C187-C196. 11. Shi S, Liu T, Wang D, Zhang Y, Liang J, Yang B and Hu D. Activation of N-methyl-d-aspartate receptors reduces heart rate variability and facilitates atrial fibrillation in rats. Europace. 2017;19:1237-1243. 12. Shi S, Liu T, Liang J, Hu D and Yang B. Depression and Risk of Sudden Cardiac Death and Arrhythmias: A Meta-Analysis. Psychosom Med. 2017;79:153-161. 13. Yang B, Yang J, Bai J, Pu P, Liu J, Wang F and Ruan B. Suv39h1 protects from myocardial ischemia-reperfusion injury in diabetic rats. Cell Physiol Biochem. 2014;33:1176-85. 14. Fo Y, Zhang C, Chen X, Liu X, Ye T, Guo Y, Qu C, Shi S and Yang B. Chronic sigma-1 receptor activation ameliorates ventricular remodeling and decreases susceptibility to ventricular arrhythmias after myocardial infarction in rats. Eur J Pharmacol. 2020;889:173614. 15. Chen X, Zhang C, Guo Y, Liu X, Ye T, Fo Y, Qu C, Liang J, Shi S and Yang B. Chronic stimulation of the sigma-1 receptor ameliorates ventricular ionic and structural remodeling in a rodent model of depression. Life Sciences. 2020;257. 16. Gao Q, Dai Z, Hu Y, Bie F and Yang B. A new method to determine the QRS axis-QRS axis determination. Clin Cardiol. 2020;43:1534-1538. 17. Guo Y, Zhang C, Chen X, Liu X, Ye T, Fo Y, Shi S, Qu C, Liang J, Shen B and Yang B. Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder. Psychopharmacology (Berl). 2020. 18. Qu C, Liu X, Guo Y, Fo Y, Chen X, Zhou J and Yang B. MiR-128-3p inhibits vascular smooth muscle cell proliferation and migration by repressing FOXO4/MMP9 signaling pathway. Mol Med. 2020;26:116. 19. Li PF, He RH, Shi SB, Li R, Wang QT, Rao GT and Yang B. Modulation of miR-10a-mediated TGF-beta1/Smads signaling affects atrial fibrillation-induced cardiac fibrosis and cardiac fibroblast proliferation. Biosci Rep. 2019;39. 20. Ye T, Liu X, Qu C, Zhang C, Fo Y, Guo Y, Chen X, Shi S and Yang B. Chronic inhibition of the sigma-1 receptor exacerbates atrial fibrillation susceptibility in rats by promoting atrial remodeling. Life Sci. 2019;235:116837. |
武汉大学人民医院
湖北省人民医院