武汉大学人民医院湖北省人民医院

院内导航

程帆 泌尿外科学
武汉大学人民医院副院长兼泌尿外科主任、泌尿外科学科带头人，教授，一级主任医师，博士生导师，湖北省第二届医学领军人才暨湖北名医工作室负责人

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导师介绍

姓名	程帆
出生年月	1969年7月
单位	武汉大学人民医院泌尿外科
所属学科	临床医学-外科学
职务、职称及头衔	武汉大学人民医院副院长兼泌尿外科主任、泌尿外科学科带头人，教授，一级主任医师，博士生导师，湖北省第二届医学领军人才暨湖北名医工作室负责人
E-mail	646064793@qq.com
联系方式	027-88041911转81286
研究方向	1.泌尿系结石的微创治疗（经皮肾镜与输尿管硬软镜技术的临床应用）；2.积水肾功能损伤的机制及其保护；3.膀胱肿瘤早期诊断与治疗。
个人简介	长期从事泌尿系结石的基础与临床研究，前列腺良、恶性疾病微创治疗技术的研究；擅长泌尿系结石、泌尿系肿瘤与前列腺疾病的微创治疗；创造性地提出“超声引导经肾盏穹隆-盏颈轴线两步穿刺法”建立安全与高效皮肾通道；医工结合，研发基于PUL的微创植入式前列腺悬吊（Urowell）手术系统与CT-US融合成像的超声引导系统（深圳卡本医疗Venus超声）。在国内外专业期刊发表论文252篇，其中以第一作者或通讯作者发表SCI论文80余篇。主持并参与国家自然科学基金7项，主持并完成省级课题7项（包括重大项目2项），主编专著2部。以第一完成人获湖北省科技进步一等奖1项、二等奖1项，湖北省首届转化医学创新大奖赛二等奖1项，湖北省教科文卫体系统第四届职工创业创新比赛创业组十佳创业奖1项。
学术任职与荣誉	中华医学会泌尿外科学分会委员中华医学会泌尿外科学分会激光学组副组长中国医师协会泌尿外科医师分会结石学组委员湖北省医学会泌尿外科学分会副主任委员湖北省医师协会泌尿外科医师分会副主任委员武汉医学会泌尿外科学分会主任委员湖北省医学领军人才暨湖北名医工作室负责人武汉东湖新技术开发区第十三批3551人才计划专家获评武汉大学医德楷模首届湖北医德楷模湖北省五一劳动奖章
教育履历	1987.09-1992.07，武汉大学，第一临床学院，临床医学专业，本科，学士学位 1995.09-2000.07，武汉大学，第一临床学院，外科学专业，研究生（硕博连读），博士学位 2003.09-2004.04，法国南锡大学医学院，泌尿外科，高级访问学者 2010.02-2011.02，英国牛津大学Nuffield外科系，泌尿外科，高级访问学者
工作履历	2000.07-2002.11，武汉大学人民医院，泌尿外科，主治医师 2002.12-2007.11，武汉大学人民医院，泌尿外科，副主任医师 2007.12-2013,11，武汉大学人民医院，泌尿外科，主任医师 2013.12-2020.11，武汉大学人民医院，泌尿外科，主任医师（二级） 2020.11-至今，武汉大学人民医院，泌尿外科，主任医师（一级） 2003.12-2010.11，武汉大学人民医院，泌尿外科，副教授 2010.11-至今，武汉大学人民医院，泌尿外科，教授 2004.07-至今,武汉大学人民医院，泌尿外科，硕士生导师 2013.06-至今，武汉大学人民医院，泌尿外科，博士生导师 2014.12-2022.10，武汉大学人民医院泌尿外III科主任，泌尿外科副主任 2022.10-至今，武汉大学人民医院泌尿外科主任，学科带头人 2017.10-2022.01，武汉大学人民医院，院长助理 2022.01-至今，武汉大学人民医院，副院长
成果获奖	1.《基于隐匿阴茎对海绵体结构和功能影响的临床技术改进》2017年获湖北省科技进步二等奖（第一完成人） 2.《基于前列腺尿道悬吊术（PUL）的微创手术治疗装置》2021年获湖北省转化医学创新奖二等奖（第一完成人） 3.《肾结石微创治疗关键技术体系构建与临床应用》2022年获湖北省科技进步一等奖（第一完成人）
代表性论著	发表论文252篇，其中以第一作者/通讯作者发表SCI论文80余篇，其中一区13篇。近五年代表论文如下（通讯作者）： 1.Li B, Xia Y, Mei S, et al. Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI. Theranostics. 2023;13(6):1860-1875.（IF:11.60,一区） 2.Ye Z, Xia Y, Li L, et al. p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis. Biomed Pharmacother. 2023;164:114925.（IF:7.42,一区） 3.Xing J, Chen W, Chen K, et al. TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB. Cancers (Basel). 2022;14(19):4809.（IF:6.58,一区） 4.Zhu S, Ma AH, Zhu Z, et al. Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer. Journal for immunotherapy of cancer.2021;9(11).（IF:12.47,一区） 5.Zhao S, Li W, Yu W, et al. Exosomal miR-21 from tubular cells contributes to renal fibrosis by activating fibroblasts via targeting PTEN in obstructed kidneys. Theranostics. 2021;11(18):8660-8673.（IF:11.60,一区） 6. Zhou X, Zhao S, Li W, et al. Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo. Int J Biol Sci. 2021;17(14):4021-4033.（IF:10.75,一区） 7. Ning JZ, He KX, Cheng F, et al. Long Non-coding RNA MEG3 Promotes Pyroptosis in Testicular Ischemia-Reperfusion Injury by Targeting MiR-29a to Modulate PTEN Expression. Frontiers in cell and developmental biology. 2021;9:671613.（IF:6.08,一区） 8. Xia Y, Zhou X, Ye Z, et al. Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones. Frontiers in genetics. 2021;12:774155.（IF:4.77,一区） 9. Han S, Lin F, Ruan Y, et al. miR-132-3p promotes the cisplatin-induced apoptosis and inflammatory response of renal tubular epithelial cells by targeting SIRT1 via the NF-κB pathway. International immunopharmacology. 2021;99:108022.（IF:5.70,一区） 10.Li P, Chen L, Liu Z, et al. Clinical features and short-term outcomes of elderly patients with COVID-19. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2020;97:245-250.（IF:12.07,一区） 11. Zhang J, Zhu L, Yao L, et al. Deep learning-based pancreas segmentation and station recognition system in EUS: development and validation of a useful training tool (with video). Gastrointest Endosc. 2020;92(4):874-885.（IF:10.30,一区） 12. Yang K, Xiao Y, Xu T, et al. Integrative analysis reveals CRHBP inhibits renal cell carcinoma progression by regulating inflammation and apoptosis. Cancer gene therapy. 2020;27(7-8):607-618.（IF:5.85,一区） 13. Li H, Li Q, Ma Z, et al. AID modulates carcinogenesis network via DNA demethylation in bladder urothelial cell carcinoma. Cell Death Dis.2019;10(4):251.（IF:9.69,一区） 14. Han S, Lin F, Qi Y, et al. HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation. Oxid Med Cell Longev. 2022;2022:3846217.（IF:6.54,二区） 15. Zheng D, Zhang Y, Xia Y, Cheng F. A Novel Gene Signature of Tripartite Motif Family for Predicting the Prognosis in Kidney Renal Clear Cell Carcinoma and Its Association With Immune Cell Infiltration. Front Oncol. 2022;12:840410.（IF:6.24,二区） 16.朱澄村,程帆,余伟民,等.输尿管软镜碎石术与微通道经皮肾镜取石术治疗<1.5 cm肾下盏结石的有效性和安全性比较.中华泌尿外科杂志.2023;44(1):32-36. 17.戚宇诚,熊庄,林方优,等.后组肾盏的分型及临床价值.中华泌尿外科杂志.2022;43(9):696-700. 18.叶泽华,夏煜琦,李柏均,等.CXCR4在草酸钙晶体致肾损伤及纤维化中的作用和机制.中华泌尿外科杂志.2022;43(4):285-290. 19.林方优,程帆,饶婷,等.不同穿刺路径经皮肾通道与肾脏血管损伤的关系.中华泌尿外科杂志.2020;41(8):624-628. 20.夏煜琦,程帆,饶婷,等.融合肾锥体解剖结构及其在B超和CT检查中的表现.中华泌尿外科杂志.2019;40(12):895-900.

Name	FAN CHENG
Date of birth	July, 1969
Department	Department of Urology, Renmin Hospital of Wuhan University
Title	Renmin Hospital of Wuhan University, Vice president, Director of urology, Urology discipline leader, Professor, Chief physician, Doctoral supervisor
Email	646064793@qq.com
TEL	027-88041911-81131
Research Direction	1. Minimally invasive treatment of urinary calculi (clinical application of percutaneous nephroscopy and ureteroscopy); 2. Mechanism and protection of hydronephrosis renal function injury; 3. Early diagnosis and treatment of bladder tumors.
Personal Profile	Cheng Fan has been engaged in basic and clinical research of urinary calculi and minimally invasive treatment of benign and malignant prostate diseases for a long time. Good at minimally invasive treatment of urinary calculi, urinary tumors and prostate diseases. The safe and efficient cutaneous renal channel was established by means of ultrasound guided two-step puncture through calyceal dome-calyceal neck axis. Through medico engineering cooperation, we developed a minimally invasive implantable prostatic urethral lift (Urowell) surgery system and an ultrasound guidance system for CT-US fusion imaging (Venus Ultrasound in Shenzhen). Cheng Fan has published 252 papers in professional journals, including more than 80 SCI papers as the first author or corresponding author. Presided over and participated in 7 National Natural Science Foundation projects, presided over and completed 7 provincial projects (including 2 major projects), edited 2 monographs. With the first complete adult won the first prize of Hubei Province science and technology progress, a second prize of Hubei Province's first translational medicine innovation Grand, a second prize of Hubei Province Education, Science, culture, health and sports system of the fourth employee entrepreneurship and innovation Competition entrepreneurial group top ten entrepreneurial award.
Selected Publications	Published 252 articles, including more than 80 SCI articles as the first author/corresponding author, 13 of which are in the SCI District 1, Chinese Academy of Sciences The representative papers in the past five years are as follows (corresponding author) : 1.Li B, Xia Y, Mei S, et al. Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI. Theranostics. 2023;13(6):1860-1875.（IF:11.60,一区） 2.Ye Z, Xia Y, Li L, et al. p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis. Biomed Pharmacother. 2023;164:114925.（IF:7.42,一区） 3.Xing J, Chen W, Chen K, et al. TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB. Cancers (Basel). 2022;14(19):4809.（IF:6.58,一区） 4.Zhu S, Ma AH, Zhu Z, et al. Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer. Journal for immunotherapy of cancer.2021;9(11).（IF:12.47,一区） 5.Zhao S, Li W, Yu W, et al. Exosomal miR-21 from tubular cells contributes to renal fibrosis by activating fibroblasts via targeting PTEN in obstructed kidneys. Theranostics. 2021;11(18):8660-8673.（IF:11.60,一区） 6. Zhou X, Zhao S, Li W, et al. Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo. Int J Biol Sci. 2021;17(14):4021-4033.（IF:10.75,一区） 7. Ning JZ, He KX, Cheng F, et al. Long Non-coding RNA MEG3 Promotes Pyroptosis in Testicular Ischemia-Reperfusion Injury by Targeting MiR-29a to Modulate PTEN Expression. Frontiers in cell and developmental biology. 2021;9:671613.（IF:6.08,一区） 8. Xia Y, Zhou X, Ye Z, et al. Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones. Frontiers in genetics. 2021;12:774155.（IF:4.77,一区） 9. Han S, Lin F, Ruan Y, et al. miR-132-3p promotes the cisplatin-induced apoptosis and inflammatory response of renal tubular epithelial cells by targeting SIRT1 via the NF-κB pathway. International immunopharmacology. 2021;99:108022.（IF:5.70,一区） 10.Li P, Chen L, Liu Z, et al. Clinical features and short-term outcomes of elderly patients with COVID-19. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2020;97:245-250.（IF:12.07,一区） 11. Zhang J, Zhu L, Yao L, et al. Deep learning-based pancreas segmentation and station recognition system in EUS: development and validation of a useful training tool (with video). Gastrointest Endosc. 2020;92(4):874-885.（IF:10.30,一区） 12. Yang K, Xiao Y, Xu T, et al. Integrative analysis reveals CRHBP inhibits renal cell carcinoma progression by regulating inflammation and apoptosis. Cancer gene therapy. 2020;27(7-8):607-618.（IF:5.85,一区） 13. Li H, Li Q, Ma Z, et al. AID modulates carcinogenesis network via DNA demethylation in bladder urothelial cell carcinoma. Cell Death Dis.2019;10(4):251.（IF:9.69,一区） 14. Han S, Lin F, Qi Y, et al. HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation. Oxid Med Cell Longev. 2022;2022:3846217.（IF:6.54,二区） 15. Zheng D, Zhang Y, Xia Y, Cheng F. A Novel Gene Signature of Tripartite Motif Family for Predicting the Prognosis in Kidney Renal Clear Cell Carcinoma and Its Association With Immune Cell Infiltration. Front Oncol. 2022;12:840410.（IF:6.24,二区） 16.朱澄村,程帆,余伟民,等.输尿管软镜碎石术与微通道经皮肾镜取石术治疗<1.5 cm肾下盏结石的有效性和安全性比较.中华泌尿外科杂志.2023;44(1):32-36. 17.戚宇诚,熊庄,林方优,等.后组肾盏的分型及临床价值.中华泌尿外科杂志.2022;43(9):696-700. 18.叶泽华,夏煜琦,李柏均,等.CXCR4在草酸钙晶体致肾损伤及纤维化中的作用和机制.中华泌尿外科杂志.2022;43(4):285-290. 19.林方优,程帆,饶婷,等.不同穿刺路径经皮肾通道与肾脏血管损伤的关系.中华泌尿外科杂志.2020;41(8):624-628. 20.夏煜琦,程帆,饶婷,等.融合肾锥体解剖结构及其在B超和CT检查中的表现.中华泌尿外科杂志.2019;40(12):895-900.