余铃
骨外
副主任医师，硕士研究生导师
副主任医师，硕士研究生导师
导师介绍
| 姓名 | 余铃 |
| 出生年月 | 1987年8月 |
| 单位 | 武汉大学人民医院骨外科 |
| 所属学科 | 临床医学-外科学 |
| 职务、职称及头衔 | 副主任医师，硕士研究生导师 |
| scaling@whu.edu.cn | |
| 联系方式 | 027-88041911转82209或13986092046 |
| 研究方向 |
1.脊柱外科 2.骨肿瘤 |
| 个人简介 | 主要从事脊柱疾病与骨肿瘤的诊治与科研工作，获国家自然科学基金青年基金1项、参与省级科研课题5项。出版专著《骨肉瘤基础与临床》，以第一作者或通讯作者身份发表论文20余篇，其中SCI论文12篇，相关成果被Nature Reviews Drug Discovery（IF=64.797）等杂志引用百余次。授权发明专利1项，实用新型专利2项。 |
| 学术任职与荣誉 |
湖北省临床肿瘤学会肉瘤专家委员会
委员 湖北省微循环学会模拟医学专业委员会 委员 湖北省生物医学工程学会颈肩腰腿痛 生物治疗专业委员会青年委员 《中国修复重建杂志》中青年编委 《巴楚医学》审稿专家 2015、2017、2018年分获武汉大学人民医院先进工作者 2019年获武汉大学人民医院安全工作先进个人 2020年评为武汉大学人民医院“人民抗疫英模” 入选武汉大学人民医院第五轮青年重点人才培养对象 入选第七批武汉市中青年医学骨干人才培养工程 |
| 教育履历 |
2004.09-2009.06武汉大学第一临床学院临床医学专业本科生获学士学位 2012.08-2013.08英国曼彻斯特大学访问博士生 2009.09-2014.06武汉大学第一临床学院外科学博士研究生获博士学位 |
| 工作履历 |
2014.07-2014.12 武汉大学人民医院骨外科住院医师 2014.12-2018.12 武汉大学人民医院骨外科主治医师 2018.12-至今 武汉大学人民医院骨外科副主任医师 2018.04-2019.04 参加湖北省第七批“博士服务团”，在咸丰县人民医院挂职副院长 2020.12-至今 武汉大学人民医院外派干部，在沙洋县人民医院挂职副院长 |
| 成果获奖 | |
| 代表性论著 |
(1).余铃,孙祥然,胡庆柱,郭卫春*.(2019/01).人工颈椎间盘置换术与颈椎前路减压融合术治疗脊髓型颈椎病的疗效比较.临床骨科杂志 (2).余铃,孙祥然,胡庆柱,郭卫春*.(2018/06). I期减压治疗颈椎管狭窄合并腰椎管狭窄症的手术方法和效果分析.中国骨与关节杂志 (3).余铃(1);张政佩(1);孙祥然(1);郑迪(1);郭卫春(1)*.(2017/10).miR-429通过靶向作用Sox2抑制骨肉瘤干细胞特性.中国医科大学学报(CSCD) (4).余铃(1);张政佩(1);陶春杰(1);郭卫春* (1);高天(2);方志伟(2);樊征夫(2)*.(2017/06).阿霉素通过激活Notch信号通路促进骨肉瘤细胞干性特性.中国肿瘤临床(CSCD) (5).Zhang, Zhengpei(1);Yu, Ling(1)*;Dai, Guo(1);Xia, Kezhou(1);Liu, Gaiwei(1);Song, Qi(1);Tao, Chunjie(1);Gao, Tian(2);Guo, Weichun(1)*.(2017/08).Telomerase reverse transcriptase promotes chemoresistance by suppressing cisplatin-dependent apoptosis in osteosarcoma cells.SCIENTIFIC REPORTS (SCI三区) (6).Dai, Guo(1)#;Yu, Ling(1)#;Yang, Jian(1);Xia, Kezhou(1);Zhang, Zhengpei(1);Liu, Gaiwei(1);Gao, Tian(2);Guo, Weichun(1)*.(2017/07).The synergistic antitumor effect of cinobufagin and cisplatin in human osteosarcoma cell line in vitro and in vivo.ONCOTARGET (SCI二区) (7).Cao, Yongfei(1)#;Yu, Ling(1)#;Dai, Guo(1)#;Zhang, Shanshan(1);Zhang, Zhengpei(1);Gao, Tian(2);Guo, Weichun(1)*.(2017/01).Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling.EUROPEAN JOURNAL OF PHARMACOLOGY (SCI三区) (8).Yu, Ling#*;Xia, Kezhou#;Gong, Changtian ;Chen, Jingteng ;Li, Wei ;Zhao, Yanan ;Guo, Weichun*;Dai, Honglian*.(2020/10).An injectable bioactive magnesium phosphate cement incorporating carboxymethyl chitosan for bone regeneration.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (SCI二区) (9).Yu, Ling#;Xia, Kezhou#;Gao, Tian#;Chen, Jingteng ;Zhang, Zhengpei ;Sun, Xiangran ;Simoes, Bruno M. ;Eyre, Rachel ;Fan, Zhengfu ;Guo, Weichun*;Clarke, Robert B*.(2019/12).The Notch Pathway Promotes Osteosarcoma Progression through Activation of Ephrin Reverse Signaling.MOLECULAR CANCER RESEARCH (SCI二区) (10).Jia, Peng(1)#;Yu, Ling(1)#;Tao, Chunjie(1);Dai, Guo(1);Zhang, Zhengpei(1);Liu, Shiqing(1)*.(2017/09).Chitosan oligosaccharides protect nucleus pulposus cells from hydrogen peroxide-induced apoptosis in a rat experimental model.BIOMEDICINE & PHARMACOTHERAPY (SCI二区) (11).Guo, Xiaodong(1)#;Yu, Ling(1)#;Zhang, Zhengpei(1);Dai, Guo(1);Gao, Tian(2);Guo, Weichun(1)*.(2017/02).miR-335 negatively regulates osteosarcoma stem cell-like properties by targeting POU5F1.CANCER CELL INTERNATIONAL (SCI二区) (12).Ji, Peng(1)#;Yu, Ling(1)#;Guo, Wei-Chun(1)*;Mei, Hong-Jun(2);Wang, Xiao-Ju(3);Chen, Hu(1);Fang, Shuo(1);Yang, Jian(1).(2015/02).Doxorubicin Inhibits Proliferation of Osteosarcoma Cells Through Upregulation of the Notch Signaling Pathway.ONCOLOGY RESEARCH (SCI二区) (13).Yu, Ling(1)#;Fan, Zhengfu(2)#;Fang, Shuo(1)#;Yang, Jian(1);Gao, Tian(2);Simoes, Bruno M.(3);Eyre, Rachel(3);Guo, Weichun(1)*;Clarke, Robert B(3)*.(2016/05).Cisplatin selects for stem-like cells in osteosarcoma by activating notch signaling.ONCOTARGET (SCI二区) (14).Gao, Tian(1)#;Yu, Ling(2)#;Fang, Zhiwei(1);Lu, Jiayong(1);Bai, Chujie(1);Li, Shu(1);Xue, Ruifeng(1);Zhang, Lu(1);Tan, Zhichao(1);Fan, Zhengfu(1)*.(2020/05).KIF18B promotes tumor progression in osteosarcoma by activating beta-catenin.CANCER BIOLOGY & MEDICINE (SCI一区) |
| Name | LING YU |
| Date of birth | Aug, 1987 |
| Department | Department of Orthopaedics (Spinal Surgery), Renmin Hospital,Wuhan University. |
| Title | Associate Chief Physician, Master Tutor |
| scaling@whu.edu.cn | |
| TEL | 027-88041911-82209 or 13986092046 |
| Research Direction |
1.
Spinal Surgery 2. Bone tumor |
| Personal Profile |
My
interest focused on the diagnosis and treatment of spinal disease and bone
tumor. My resarch was funded by the National Natural Science Fundation of China and several provincial research projects. I have published more than 20 papers (including 12 SCI papers). The results was cited by leading journals such as Nature Reviews Drug Discovery (if = 64.797) for more than 100 times. In addition, 3 patents were granted including one invention patent. |
| Selected Publications |
(1).余铃,孙祥然,胡庆柱,郭卫春*.(2019/01).人工颈椎间盘置换术与颈椎前路减压融合术治疗脊髓型颈椎病的疗效比较.临床骨科杂志 (2).余铃,孙祥然,胡庆柱,郭卫春*.(2018/06). I期减压治疗颈椎管狭窄合并腰椎管狭窄症的手术方法和效果分析.中国骨与关节杂志 (3).余铃(1);张政佩(1);孙祥然(1);郑迪(1);郭卫春(1)*.(2017/10).miR-429通过靶向作用Sox2抑制骨肉瘤干细胞特性.中国医科大学学报(CSCD) (4).余铃(1);张政佩(1);陶春杰(1);郭卫春* (1);高天(2);方志伟(2);樊征夫(2)*.(2017/06).阿霉素通过激活Notch信号通路促进骨肉瘤细胞干性特性.中国肿瘤临床(CSCD) (5).Zhang, Zhengpei(1);Yu, Ling(1)*;Dai, Guo(1);Xia, Kezhou(1);Liu, Gaiwei(1);Song, Qi(1);Tao, Chunjie(1);Gao, Tian(2);Guo, Weichun(1)*.(2017/08).Telomerase reverse transcriptase promotes chemoresistance by suppressing cisplatin-dependent apoptosis in osteosarcoma cells.SCIENTIFIC REPORTS (SCI三区) (6).Dai, Guo(1)#;Yu, Ling(1)#;Yang, Jian(1);Xia, Kezhou(1);Zhang, Zhengpei(1);Liu, Gaiwei(1);Gao, Tian(2);Guo, Weichun(1)*.(2017/07).The synergistic antitumor effect of cinobufagin and cisplatin in human osteosarcoma cell line in vitro and in vivo.ONCOTARGET (SCI二区) (7).Cao, Yongfei(1)#;Yu, Ling(1)#;Dai, Guo(1)#;Zhang, Shanshan(1);Zhang, Zhengpei(1);Gao, Tian(2);Guo, Weichun(1)*.(2017/01).Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling.EUROPEAN JOURNAL OF PHARMACOLOGY (SCI三区) (8).Yu, Ling#*;Xia, Kezhou#;Gong, Changtian ;Chen, Jingteng ;Li, Wei ;Zhao, Yanan ;Guo, Weichun*;Dai, Honglian*.(2020/10).An injectable bioactive magnesium phosphate cement incorporating carboxymethyl chitosan for bone regeneration.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (SCI二区) (9).Yu, Ling#;Xia, Kezhou#;Gao, Tian#;Chen, Jingteng ;Zhang, Zhengpei ;Sun, Xiangran ;Simoes, Bruno M. ;Eyre, Rachel ;Fan, Zhengfu ;Guo, Weichun*;Clarke, Robert B*.(2019/12).The Notch Pathway Promotes Osteosarcoma Progression through Activation of Ephrin Reverse Signaling.MOLECULAR CANCER RESEARCH (SCI二区) (10).Jia, Peng(1)#;Yu, Ling(1)#;Tao, Chunjie(1);Dai, Guo(1);Zhang, Zhengpei(1);Liu, Shiqing(1)*.(2017/09).Chitosan oligosaccharides protect nucleus pulposus cells from hydrogen peroxide-induced apoptosis in a rat experimental model.BIOMEDICINE & PHARMACOTHERAPY (SCI二区) (11).Guo, Xiaodong(1)#;Yu, Ling(1)#;Zhang, Zhengpei(1);Dai, Guo(1);Gao, Tian(2);Guo, Weichun(1)*.(2017/02).miR-335 negatively regulates osteosarcoma stem cell-like properties by targeting POU5F1.CANCER CELL INTERNATIONAL (SCI二区) (12).Ji, Peng(1)#;Yu, Ling(1)#;Guo, Wei-Chun(1)*;Mei, Hong-Jun(2);Wang, Xiao-Ju(3);Chen, Hu(1);Fang, Shuo(1);Yang, Jian(1).(2015/02).Doxorubicin Inhibits Proliferation of Osteosarcoma Cells Through Upregulation of the Notch Signaling Pathway.ONCOLOGY RESEARCH (SCI二区) (13).Yu, Ling(1)#;Fan, Zhengfu(2)#;Fang, Shuo(1)#;Yang, Jian(1);Gao, Tian(2);Simoes, Bruno M.(3);Eyre, Rachel(3);Guo, Weichun(1)*;Clarke, Robert B(3)*.(2016/05).Cisplatin selects for stem-like cells in osteosarcoma by activating notch signaling.ONCOTARGET (SCI二区) (14).Gao, Tian(1)#;Yu, Ling(2)#;Fang, Zhiwei(1);Lu, Jiayong(1);Bai, Chujie(1);Li, Shu(1);Xue, Ruifeng(1);Zhang, Lu(1);Tan, Zhichao(1);Fan, Zhengfu(1)*.(2020/05).KIF18B promotes tumor progression in osteosarcoma by activating beta-catenin.CANCER BIOLOGY & MEDICINE (SCI一区) |
武汉大学人民医院
湖北省人民医院