张艳
检验
副主任技师、硕士生导师
副主任技师、硕士生导师
导师介绍
| 姓名 | 张艳 |
| 出生年月 | 1985年3月 |
| 单位 | 武汉大学人民医院检验科 |
| 所属学科 | 临床医学-临床检验诊断学 |
| 职务、职称及头衔 | 副主任技师、硕士生导师 |
| peneyyan@whu.edu.cn | |
| 联系方式 | 027-88041911转81320 |
| 研究方向 |
1.生殖免疫、妇产科相关分子诊断 2.遗传病的产前分子诊断 |
| 个人简介 | 主要从事遗传病的分子诊断与科研工作，获国家自然科学基金1项。以第一作者或通讯作者发表SCI论文10余篇。 |
| 学术任职与荣誉 | 无 |
| 教育履历 |
2004.09-2008.06中国科学技术大学生命科学专业本科生获学士学位 2011.09-2013.06武汉大学药学院硕士研究生获硕士学位 2014.09-2017.06华中科技大学计划生育研究所妇产科学博士研究生获博士学位 |
| 工作履历 |
2017.07-2017.11 武汉大学人民医院检验科技师 2017.12-2019.11武汉大学人民医院检验科主管技师 2019.12-至今 武汉大学人民医院检验科副主任技师 |
| 成果获奖 |
1.《卵母细胞和胚胎无创评估、监测体系的研发及应用》2020年获湖北省科技进步二等奖 |
| 代表性论著 |
1.Zhou
Q#, Zhang Y#, Zou Y#, Yin T*, Yang J*. Human embryo gene editing: God's
scalpel or Pandora's box? Brief Funct Genomics. 2020 May 20;19(3):154-163.
doi: 10.1093/bfgp/elz025. 2.Xie D, Zhang J, Ding J, Yang J*, Zhang Y*. OLA1 is responsible for normal spindle assembly and SAC activation in mouse oocytes. PeerJ. 2020 Jan 3;8:e8180. doi: 10.7717/peerj.8180. 3.Pei WD#, Zhang Y#, Yin TL*, Yu Y*. Epigenome editing by CRISPR/Cas9 in clinical settings: possibilities and challenges. Brief Funct Genomics. 2020 May 20;19(3):215-228. doi: 10.1093/bfgp/elz035. 4.Qu B#, Zhao Q#, Ma Q, Yang T, Li X, Chen Y, Yang J*, Zhang Y*. Overexpression of miR-144-3p alleviates polycystic ovaries syndrome through targeting expression of HSP-70. Gene Ther. 2020 Sep 11. doi: 10.1038/s41434-020-00191-0. 5.Zhu Qikui#, Liang Li#, Jiangnan Hao, YunfeiZha#, Yan Zhang*, Yanxiang Cheng*, Fei Liao*, and Pingxiang Li#. Selective information passing for MR/CT image segmentation. Neural Computing and Applications. 2020 Oct ;1. doi:10.1007/s00521-020-05407-3 6.Xia A#, Zhang Y#, Xu J#, Yin T*, Lu XJ*. T Cell Dysfunction in Cancer Immunity and Immunotherapy. Front Immunol. 2019 Jul 19;10:1719. doi:10.3389/fimmu.2019.01719. 7.Yin ZN, Ding JL, Zhang Y, Li SJ, Zhang Y*, Yang J*. Expression of E2A in mid-secretory endometrium of women suffering from recurrent miscarriage. J Huazhong Univ Sci Technolog Med Sci. 2017 Dec;37(6):910-914. doi: 10.1007/s11596-017-1826-5. 8.Zhang Y#, Liu L#*, Yin TL, Yang J*, Xiong CL*. Follicular metabolic changes and effects on oocyte quality in polycystic ovary syndrome patients. Oncotarget. 2017 Jul 6;8(46):80472-80480. doi: 10.18632/oncotarget.19058. 9.Ding J#, Zhang Y#, Cai X*, Zhang Y, Yan S, Wang J, Zhang S, Yin T*, Yang C*, Yang J*. Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion. Theranostics. 2021 Mar 31;11(12):5813-5830. doi: 10.7150/thno.58731. 10.Xian S#, Zhang Y#, Wang L, Yao F, Ding J, Wang Y, Yang X, Dai F, Yin T*, Cheng Y*. INO80 participates in the pathogenesis of recurrent miscarriage by epigenetically regulating trophoblast migration and invasion. J Cell Mol Med. 2021 Apr;25(8):3885-3897. doi: 10.1111/jcmm.16322. |
| Name | YAN ZHANG |
| Date of birth | Mar，1985 |
| Department | Department of Laboratory Science，Renmin Hospital,Wuhan University. |
| Title | Associate senior technologist |
| peneyyan@whu.edu.cn | |
| TEL | 027-88041911转81320 |
| Research Direction |
1.
Reproductive immunity, obstetrics and gynecology related molecular
diagnosis 2. Prenatal molecular diagnosis of genetic diseases |
| Personal Profile | She is mainly engaged in molecular diagnosis and scientific research of genetic diseases, ,and has been awarded 1 item for the National Natural Science Foundation, has published more than 10 SCI papers as the first author or corresponding author. |
| Selected Publications |
1.Zhou
Q#, Zhang Y#, Zou Y#, Yin T*, Yang J*. Human embryo gene editing: God's
scalpel or Pandora's box? Brief Funct Genomics. 2020 May 20;19(3):154-163.
doi: 10.1093/bfgp/elz025. 2.Xie D, Zhang J, Ding J, Yang J*, Zhang Y*. OLA1 is responsible for normal spindle assembly and SAC activation in mouse oocytes. PeerJ. 2020 Jan 3;8:e8180. doi: 10.7717/peerj.8180. 3.Pei WD#, Zhang Y#, Yin TL*, Yu Y*. Epigenome editing by CRISPR/Cas9 in clinical settings: possibilities and challenges. Brief Funct Genomics. 2020 May 20;19(3):215-228. doi: 10.1093/bfgp/elz035. 4.Qu B#, Zhao Q#, Ma Q, Yang T, Li X, Chen Y, Yang J*, Zhang Y*. Overexpression of miR-144-3p alleviates polycystic ovaries syndrome through targeting expression of HSP-70. Gene Ther. 2020 Sep 11. doi: 10.1038/s41434-020-00191-0. 5.Zhu Qikui#, Liang Li#, Jiangnan Hao, YunfeiZha#, Yan Zhang*, Yanxiang Cheng*, Fei Liao*, and Pingxiang Li#. Selective information passing for MR/CT image segmentation. Neural Computing and Applications. 2020 Oct ;1. doi:10.1007/s00521-020-05407-3 6.Xia A#, Zhang Y#, Xu J#, Yin T*, Lu XJ*. T Cell Dysfunction in Cancer Immunity and Immunotherapy. Front Immunol. 2019 Jul 19;10:1719. doi:10.3389/fimmu.2019.01719. 7.Yin ZN, Ding JL, Zhang Y, Li SJ, Zhang Y*, Yang J*. Expression of E2A in mid-secretory endometrium of women suffering from recurrent miscarriage. J Huazhong Univ Sci Technolog Med Sci. 2017 Dec;37(6):910-914. doi: 10.1007/s11596-017-1826-5. 8.Zhang Y#, Liu L#*, Yin TL, Yang J*, Xiong CL*. Follicular metabolic changes and effects on oocyte quality in polycystic ovary syndrome patients. Oncotarget. 2017 Jul 6;8(46):80472-80480. doi: 10.18632/oncotarget.19058. 9.Ding J#, Zhang Y#, Cai X*, Zhang Y, Yan S, Wang J, Zhang S, Yin T*, Yang C*, Yang J*. Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion. Theranostics. 2021 Mar 31;11(12):5813-5830. doi: 10.7150/thno.58731. 10.Xian S#, Zhang Y#, Wang L, Yao F, Ding J, Wang Y, Yang X, Dai F, Yin T*, Cheng Y*. INO80 participates in the pathogenesis of recurrent miscarriage by epigenetically regulating trophoblast migration and invasion. J Cell Mol Med. 2021 Apr;25(8):3885-3897. doi: 10.1111/jcmm.16322. |
武汉大学人民医院
湖北省人民医院