武汉大学人民医院湖北省人民医院

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李斐神外
副主任医师，硕士生导师

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导师介绍

姓名	李斐
出生年月	1982年12月
单位	武汉大学人民医院神经外科
所属学科	临床医学-外科学
职务、职称及头衔	副主任医师，硕士生导师
E-mail	wdlf1981@163.com
联系方式	027-88041911转83320或18986396700
研究方向	脑血管病的基础与临床
个人简介	主要从事神经系统疾病的诊治与科研工作，擅长颅脑损伤、脑血管病、脑肿瘤、椎管内肿瘤、三叉神经痛、舌咽神经痛、面肌痉挛、脑积水等疾病的诊断及治疗。对颅脑损伤、脑血管病、中枢神经系统肿瘤相关的神经外科急危重症的诊疗具有丰富的临床经验。获国家自然科学基金1项、省科技厅等课题2项。以第一作者或通讯作者身份发表论文20余篇，其中SCI论文十余篇。
学术任职与荣誉	国家科技专家库专家国家自然科学基金项目评审专家湖北省科技厅权威专家库入库专家湖北省科技项目评审专家武汉市科技局专家库专家《中华创伤杂志》青年学术委员会委员《Journal of Neurology》、《Journal of Intensive Care Medicine》、《Postgraduate Medicine》特约审稿专家
教育履历	2000.09-2005.06武汉大学医学部临床医学专业本科生获学士学位 2005.09-2007.06武汉大学第二临床学院外科学硕士研究生获硕士学位 2011.12-2014.12武汉大学第一临床学院外科学博士研究生获博士学位
工作履历	2007.07-2013.03 湖北医药学院附属襄阳医院神经外科住院医师 2013.04-2015.05 湖北医药学院附属襄阳医院神经外科主治医师 2015.06-2018.11 武汉大学人民医院神经外科主治医师 2018.12-至今武汉大学人民医院神经外科副主任医师
成果获奖	《脑卒中神经保护的相关分子机制及精准治疗》2021年获湖北省科技进步二等奖
代表性论著	1.Fei Li, Hong-Xiang Jiang, Hui-Kai Zhang, Qian-Xue Chen. TUG1 aggravates intracerebral hemorrhage injury by inhibiting angiogenesis in an miR-26a-dependent manner. Am J Transl Res, 2023, 15(1): 175-183. 2.Hongxiang Jiang, Zhiqiang Sun, Fei Li, Qianxue Chen. Prognostic value of γ-aminobutyric acidergic synapse-associated signature for lower-grade gliomas. Front Immunol, 2022, 13: 983569. 3.Fei Li, Jun-Hua Yu, Hong-Xiang Jiang, Hui-Kai Zhang, Qiang Cai, Zai-Ming Liu, Ming-Chang Li, Qian-Xue Chen. Taurine-Upregulated Gene 1 Attenuates Cerebral Angiogenesis following Ischemic Stroke in Rats. Biomed Res Int, 2022, 2022: 1037525. 4.Hongxiang Jiang, Fei Li, Linzhi Cai, Qianxue Chen. Role of the TSPO-NOX4 axis in angiogenesis in glioblastoma. Front Pharmacol, 2022, 13: 1001588. 5.Fei Li, Qian-Xue Chen, Bo Peng, Yan Chen, Tao Yao, Guan Wang. Microalbuminuria in patients with acute ischemic stroke. Neurol Res, 2019, 41(6): 498-503. 6.Fei Li, Qian-Xue Chen, Yan Chen, Guan Wang, Bo Peng, Tao Yao. Prevalence and risk factors of microalbuminuria in patients with lacunar infarction. Postgrad Med, 2019, 131(5): 342-347. 7.Fei Li, Qian-Xue Chen, Shou-Gui Xiang, Shi-Zhun Yuan, Xi-Zhen Xu. N-Terminal Pro-Brain Natriuretic Peptide Concentrations After Hypertensive Intracerebral Hemorrhage: Relationship With Hematoma Size, Hyponatremia, and Intracranial Pressure. Journal of Intensive Care Medicine, 2018, 33(12):663-670 8.Fei Li, Qian-Xue Chen, Shou-Gui Xiang, Shi-Zhun Yuan, Xi-Zhen Xu. The role of N-terminal pro-brain natriuretic peptide in evaluating the prognosis of patients with intracerebral hemorrhage. JOURNAL OF NEUROLOGY, 2017, 264(10): 2081-2087. 9.Fei Li, Qian-Xue Chen, Zhi-Biao Chen, Dao-Feng Tian, Qiang Cai. Magnetic Resonance Imaging of Plaque Burden in Vascular Walls of the Middle Cerebral Artery Correlates with Cerebral Infarction. Current Neurovascular Research, 2016, 13(4): 263-270. 10.Fei Li, Qian-Xue Chen. Cerebral hernia induced by intracerebral hematoma in patients with poor-grade ruptured intracranial aneurysm: emergent surgical treatment without angiography. International Journal of Clinical and Experimental Medicine, 2016, 9(3): 6935-6942. 11.Fei Li, Qian-Xue Chen. Risk factors for mental disorders in patients with hypertensive intracerebral hemorrhage following neurosurgical treatment. Journal of the Neurological Sciences, 2014, 341(1-2): 128-132. 12.李斐，陈谦学，王军民，柳再明，叶晖，周龙.颅内动脉瘤介入栓塞相关性脑血栓事件的危险因素分析.华西医学. 2021，36(7):889-893 13.李斐，陈谦学，柳再明，叶晖，周龙.颅内动脉瘤破裂并发脑内血肿的危险因素.中国临床神经外科杂志. 2019，24(05):266-268. 14.李斐，陈谦学.中脑周围非动脉瘤性蛛网膜下腔出血的临床特点.国际神经病学神经外科学杂志. 2018，45(01):10-13. 15.李斐，陈谦学，陈治标，叶应湖，蔡强.不同手术策略治疗动脉瘤性颅内血肿并脑疝的疗效分析.医学研究杂志. 2017，46(10):4-6+10. 16.李斐，陈谦学，陈治标，叶应湖，蔡强，王龙，邓钢，刘骏辉.前颅窝底巨大脑膜瘤的显微手术治疗.武汉大学学报(医学版). 2017，38(02):289-292. 17.李斐，陈谦学，田道锋，李明昌，蔡强，王军民. 60岁以上患者脑动静脉畸形23例临床分析.临床外科杂志. 2016，24(04):287-289. 18.李斐，陈谦学，刘宝辉，田道锋，李明昌，张申起.神经生长因子和增殖细胞核抗原在人脑胶质瘤中的表达及意义.武汉大学学报(医学版). 2015，36(03):386-388+415. 19.李斐，陈谦学，李明昌，王军民，田道锋，张申起.创伤性颅内假性动脉瘤的临床治疗.中华创伤杂志. 2014，30(11):1112-1114. 20.李斐.单孔钻颅负压引流治疗慢性硬膜下血肿60例疗效分析.中华神经外科杂志. 2009(01):11.

Name	FEI LI
Date of birth	December, 1982
Department	Neurosurgery Department, Renmin Hospital, Wuhan University.
Title	Associate chief physician, Master tutor
Email	wdlf1981@163.com
TEL	027-88041911-83320 or 18986396700
Research Direction	Basic and clinical study of cerebrovascular disease
Personal Profile	He is mainly engaged in the diagnosis and treatment of nervous system diseases, and is good at the diagnosis and treatment of craniocerebral injury, cerebrovascular disease, brain tumor, intraspinal tumor, trigeminal neuralgia, glossopharyngeal neuralgia, hemifacial spasm, hydrocephalus, and so on. He has rich clinical experience in the diagnosisand treatment of neurosurgical critical diseases related to craniocerebral injury, cerebrovascular disease and central nervous system tumor, and has been awarded 1 project from the National Natural Science Foundation of China, 2 projects from the Provincial Science and Technology Department and the Provincial Health Department. Besides, he has published over 20 papers as the first author or corresponding author, including more than 10 SCI papers.
Selected Publications	1.Fei Li, Hong-Xiang Jiang, Hui-Kai Zhang, Qian-Xue Chen. TUG1 aggravates intracerebral hemorrhage injury by inhibiting angiogenesis in an miR-26a-dependent manner. Am J Transl Res, 2023, 15(1): 175-183. 2.Hongxiang Jiang, Zhiqiang Sun, Fei Li, Qianxue Chen. Prognostic value of γ-aminobutyric acidergic synapse-associated signature for lower-grade gliomas. Front Immunol, 2022, 13: 983569. 3.Fei Li, Jun-Hua Yu, Hong-Xiang Jiang, Hui-Kai Zhang, Qiang Cai, Zai-Ming Liu, Ming-Chang Li, Qian-Xue Chen. Taurine-Upregulated Gene 1 Attenuates Cerebral Angiogenesis following Ischemic Stroke in Rats. Biomed Res Int, 2022, 2022: 1037525. 4.Hongxiang Jiang, Fei Li, Linzhi Cai, Qianxue Chen. Role of the TSPO-NOX4 axis in angiogenesis in glioblastoma. Front Pharmacol, 2022, 13: 1001588. 5.Fei Li, Qian-Xue Chen, Bo Peng, Yan Chen, Tao Yao, Guan Wang. Microalbuminuria in patients with acute ischemic stroke. Neurol Res, 2019, 41(6): 498-503. 6.Fei Li, Qian-Xue Chen, Yan Chen, Guan Wang, Bo Peng, Tao Yao. Prevalence and risk factors of microalbuminuria in patients with lacunar infarction. Postgrad Med, 2019, 131(5): 342-347. 7.Fei Li, Qian-Xue Chen, Shou-Gui Xiang, Shi-Zhun Yuan, Xi-Zhen Xu. N-Terminal Pro-Brain Natriuretic Peptide Concentrations After Hypertensive Intracerebral Hemorrhage: Relationship With Hematoma Size, Hyponatremia, and Intracranial Pressure. Journal of Intensive Care Medicine, 2018, 33(12):663-670 8.Fei Li, Qian-Xue Chen, Shou-Gui Xiang, Shi-Zhun Yuan, Xi-Zhen Xu. The role of N-terminal pro-brain natriuretic peptide in evaluating the prognosis of patients with intracerebral hemorrhage. JOURNAL OF NEUROLOGY, 2017, 264(10): 2081-2087. 9.Fei Li, Qian-Xue Chen, Zhi-Biao Chen, Dao-Feng Tian, Qiang Cai. Magnetic Resonance Imaging of Plaque Burden in Vascular Walls of the Middle Cerebral Artery Correlates with Cerebral Infarction. Current Neurovascular Research, 2016, 13(4): 263-270. 10.Fei Li, Qian-Xue Chen. Cerebral hernia induced by intracerebral hematoma in patients with poor-grade ruptured intracranial aneurysm: emergent surgical treatment without angiography. International Journal of Clinical and Experimental Medicine, 2016, 9(3): 6935-6942. 11.Fei Li, Qian-Xue Chen. Risk factors for mental disorders in patients with hypertensive intracerebral hemorrhage following neurosurgical treatment. Journal of the Neurological Sciences, 2014, 341(1-2): 128-132.