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  • 王少亭 检验
    副主任药师、副教授
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    导师介绍

    姓名 王少亭
    出生年月 1988年2月
    单位 武汉大学第一临床学院
    所属学科 临床检验诊断学
    职务、职称及头衔 副主任药师;副教授
    E-mail shaotingw@whu.edu.cn
    联系方式 88041911-81176
    研究方向 临床质谱检测方法学的建立及应用
    个人简介 主要从事临床质谱方法学建立及应用。主持国家自然科学基金1项。一作及通讯作者在Analytical Chemistry、Free Radical Biology and Medicine等期刊发表SCI论文二十余篇(其中二区以上论文十余篇)。任Analytica Chimica Acta、Talanta、Food Chemistry、Journal of Chromatography A、Clinical Chemistry and Laboratory Medicine等TOP期刊审稿人。
    学术任职与荣誉 Invited reviewer for Analytica Chimica Acta (from 2023); Annals of Medicine (from 2022); Analyst (from 2022); Food Chemistry (from 2021); Journal of Pharmaceutical and Biomedical Analysis (from 2020); Talanta (from 2019); Clinical Chemistry and Laboratory Medicine (from 2019); RSC Advances (from 2019); Biomedical Chromatography (from 2018); Journal of Chromatography A (from 2017)
    教育履历 2006.09-2010.06武汉大学化学与分子科学学院化学基地班获学士学位;2010.09-2015.06武汉大学化学与分子科学学院分析化学获博士学位
    工作履历 2015.07-2016.07 武汉大学人民医院检验科 药师;2016.07-2018.11 武汉大学人民医院检验科 主管药师;2018.11-至今 武汉大学人民医院检验科 副主任药师
    成果获奖
    代表性论著 近五年第一作者及通讯作者学术论文:
    1. Wang, Hai-Bo; Peng, Rui; Le, Juan; Wang, Shao-Ting. LC-MS/MS quantification of vitamin K1 after simple precipitation of protein from low volume of serum. Arabian Journal of Chemistry (2023). 16, 105023 DOI: https://doi.org/10.1016/j.arabjc.2023.105023
    2. Peng, Rui; Le, Juan; Yang, Shu-Lin; Cheng, Jing-Ru; Li, Yan; Wang, Shao-Ting. Cold-induced phase separation for the simple and reliable extraction of sex hormones for subsequent LC-MS/MS analysis. Journal of Lipid Research (2022). 63, 100158 DOI: 10.1016/j.jlr.2021.100158
    3. Liao, Hui-Yang; Xiao, Xuan; Peng, Rui; Le, Juan; Wang, Hai-Bo; Wang, Shao-Ting. Rapid Derivatization of Phenolic and Oxime Hydroxyl with Isonicotinoyl Chloride under Aqueous Conditions and Its Application in LC–MS/MS Profiling Multiclass Steroids. Analytical Chemistry (2022). 94, 17980-17987 DOI: 10.1021/acs.analchem.2c04151
    4. Le, Juan; Peng, Rui; Yang, Shu-Lin; Chen, Jian-Li; Cheng, Jing-Ru; Li, Yan; Wang, Shao-Ting. Quantification of immunosuppressants from one 3.2 mm dried blood spot by a novel cold-induced phase separation based LC-MS/MS method. Analytica Chimica Acta (2022). 1210, 339889 DOI: 10.1016/j.aca.2022.339889
    5. Yuan, Teng-Fei; Wang, Shao-Ting; Le, Juan; Li, Yan. Steroid profile analysis by liquid chromatography-tandem mass spectrometry in second-trimester pregnant women for trisomy 21 screening. Journal of Pharmaceutical and Biomedical Analysis (2021). 197, 113966 DOI: 10.1016/j.jpba.2021.113966
    6. Yang, Shu-Lin; Le, Juan; Peng, Rui; Wang, Shao-Ting; Li, Yan. Influence of Tacrolimus on Serum Vitamin A Levels in Patients after Renal Transplantation. Laboratory Medicine (2021). 53, 296-301 DOI: 10.1093/labmed/lmab102
    7. Yuan, Teng-Fei; Wang, Shao-Ting; Le, Juan; Li, Yan. Effects of Atypical Antipsychotics on Neuroactive Vitamins in Patients With Schizophrenia. Journal of Clinical Pharmacology (2020). 60, 1355-1361 DOI: 10.1002/jcph.1625
    8. Yuan, Teng-Fei; Le, Juan; Wang, Shao-Ting; Li, Yan. An LC/MS/MS method for analyzing the steroid metabolome with high accuracy and from small serum samples. Journal of Lipid Research (2020). 61, 580-586 DOI: 10.1194/jlr.D119000591
    9. Wang, Shao-Ting; Le, Juan; Peng, Rui; Li, Yan. Efficient extraction and sensitive LC-MS quantification of hydroxytyrosol in wine, oil and plasma. Food Chemistry (2020). 323, 126803 DOI: 10.1016/j.foodchem.2020.126803
    10. Le, Juan; Sun, Ting; Peng, Rui; Yuan, Teng-Fei; Feng, Yu-Qi; Wang, Shao-Ting; Li, Yan. LC-MS/MS determination of plasma catecholamines after selective extraction by borated zirconia. Microchimica Acta (2020). 187, 165 DOI: 10.1007/s00604-020-4145-7
    11. Yuan, Teng-Fei; Le, Juan; Cui, Yan; Peng, Rui; Wang, Shao-Ting; Li, Yan. An LC-MS/MS analysis for seven sex hormones in serum. Journal of Pharmaceutical and Biomedical Analysis (2019). 162, 34-40 DOI: https://doi.org/10.1016/j.jpba.2018.09.014
    12. Le, Juan; Yuan, Teng-Fei; Geng, Jia-Qing; Wang, Shao-Ting; Li, Yan; Zhang, Bing-Hong. Acylation derivatization based LC-MS analysis of 25-hydroxyvitamin D from finger-prick blood. Journal of Lipid Research (2019). 60, 1058-1064 DOI: 10.1194/jlr.D092197
    13. Yuan, Teng-Fei; Huang, Han-Qi; Gao, Ling; Wang, Shao-Ting; Li, Yan. A novel and reliable method for tetrahydrobiopterin quantification: Benzoyl chloride derivatization coupled with liquid chromatography-tandem mass spectrometry analysis. Free Radical Biology and Medicine (2018). 118, 119-125 DOI: 10.1016/j.freeradbiomed.2018.02.035
    14. Le, Juan; Yuan, Teng-Fei; Zhang, Yan; Wang, Shao-Ting; Li, Yan. New LC-MS/MS method with single-step pretreatment analyzes fat-soluble vitamins in plasma and amniotic fluid. Journal of Lipid Research (2018). 59, 1783-1790 DOI: 10.1194/jlr.D087569
    Name Shao-Ting Wang
    Date of birth 1988.2
    Department Department of Clinical Laboratory, Renmin Hospital, Wuhan University.
    Title Vice Chief Pharmacist
    Email shaotingw@whu.edu.cn
    TEL 027-88041911-81176
    Research Direction Development and application of clinical LC-MS/MS methods
    Personal Profile He is a doctor of chemistry working as a pharmacist in clinical laboratory. He is mainly engaged in the development and application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods in clinical field. One item from the National Natural Science Foundation has been awarded. Over 20 SCI papers have been published as the first/corresponding author.By now, he is the invited reviewer for tens of TOP journals including Talanta, Journal of Chromatography A, Clinical Chemistry and Laboratory Medicine and so on.  ORCID (0000-0001-9976-0445)
    Selected Publications 近五年第一作者及通讯作者学术论文:
    1. Wang, Hai-Bo; Peng, Rui; Le, Juan; Wang, Shao-Ting. LC-MS/MS quantification of vitamin K1 after simple precipitation of protein from low volume of serum. Arabian Journal of Chemistry (2023). 16, 105023 DOI: https://doi.org/10.1016/j.arabjc.2023.105023
    2. Peng, Rui; Le, Juan; Yang, Shu-Lin; Cheng, Jing-Ru; Li, Yan; Wang, Shao-Ting. Cold-induced phase separation for the simple and reliable extraction of sex hormones for subsequent LC-MS/MS analysis. Journal of Lipid Research (2022). 63, 100158 DOI: 10.1016/j.jlr.2021.100158
    3. Liao, Hui-Yang; Xiao, Xuan; Peng, Rui; Le, Juan; Wang, Hai-Bo; Wang, Shao-Ting. Rapid Derivatization of Phenolic and Oxime Hydroxyl with Isonicotinoyl Chloride under Aqueous Conditions and Its Application in LC–MS/MS Profiling Multiclass Steroids. Analytical Chemistry (2022). 94, 17980-17987 DOI: 10.1021/acs.analchem.2c04151
    4. Le, Juan; Peng, Rui; Yang, Shu-Lin; Chen, Jian-Li; Cheng, Jing-Ru; Li, Yan; Wang, Shao-Ting. Quantification of immunosuppressants from one 3.2 mm dried blood spot by a novel cold-induced phase separation based LC-MS/MS method. Analytica Chimica Acta (2022). 1210, 339889 DOI: 10.1016/j.aca.2022.339889
    5. Yuan, Teng-Fei; Wang, Shao-Ting; Le, Juan; Li, Yan. Steroid profile analysis by liquid chromatography-tandem mass spectrometry in second-trimester pregnant women for trisomy 21 screening. Journal of Pharmaceutical and Biomedical Analysis (2021). 197, 113966 DOI: 10.1016/j.jpba.2021.113966
    6. Yang, Shu-Lin; Le, Juan; Peng, Rui; Wang, Shao-Ting; Li, Yan. Influence of Tacrolimus on Serum Vitamin A Levels in Patients after Renal Transplantation. Laboratory Medicine (2021). 53, 296-301 DOI: 10.1093/labmed/lmab102
    7. Yuan, Teng-Fei; Wang, Shao-Ting; Le, Juan; Li, Yan. Effects of Atypical Antipsychotics on Neuroactive Vitamins in Patients With Schizophrenia. Journal of Clinical Pharmacology (2020). 60, 1355-1361 DOI: 10.1002/jcph.1625
    8. Yuan, Teng-Fei; Le, Juan; Wang, Shao-Ting; Li, Yan. An LC/MS/MS method for analyzing the steroid metabolome with high accuracy and from small serum samples. Journal of Lipid Research (2020). 61, 580-586 DOI: 10.1194/jlr.D119000591
    9. Wang, Shao-Ting; Le, Juan; Peng, Rui; Li, Yan. Efficient extraction and sensitive LC-MS quantification of hydroxytyrosol in wine, oil and plasma. Food Chemistry (2020). 323, 126803 DOI: 10.1016/j.foodchem.2020.126803
    10. Le, Juan; Sun, Ting; Peng, Rui; Yuan, Teng-Fei; Feng, Yu-Qi; Wang, Shao-Ting; Li, Yan. LC-MS/MS determination of plasma catecholamines after selective extraction by borated zirconia. Microchimica Acta (2020). 187, 165 DOI: 10.1007/s00604-020-4145-7
    11. Yuan, Teng-Fei; Le, Juan; Cui, Yan; Peng, Rui; Wang, Shao-Ting; Li, Yan. An LC-MS/MS analysis for seven sex hormones in serum. Journal of Pharmaceutical and Biomedical Analysis (2019). 162, 34-40 DOI: https://doi.org/10.1016/j.jpba.2018.09.014
    12. Le, Juan; Yuan, Teng-Fei; Geng, Jia-Qing; Wang, Shao-Ting; Li, Yan; Zhang, Bing-Hong. Acylation derivatization based LC-MS analysis of 25-hydroxyvitamin D from finger-prick blood. Journal of Lipid Research (2019). 60, 1058-1064 DOI: 10.1194/jlr.D092197
    13. Yuan, Teng-Fei; Huang, Han-Qi; Gao, Ling; Wang, Shao-Ting; Li, Yan. A novel and reliable method for tetrahydrobiopterin quantification: Benzoyl chloride derivatization coupled with liquid chromatography-tandem mass spectrometry analysis. Free Radical Biology and Medicine (2018). 118, 119-125 DOI: 10.1016/j.freeradbiomed.2018.02.035
    14. Le, Juan; Yuan, Teng-Fei; Zhang, Yan; Wang, Shao-Ting; Li, Yan. New LC-MS/MS method with single-step pretreatment analyzes fat-soluble vitamins in plasma and amniotic fluid. Journal of Lipid Research (2018). 59, 1783-1790 DOI: 10.1194/jlr.D087569