吴飞
骨外
科主任，主任医师，硕士生导师
科主任，主任医师，硕士生导师
导师介绍
| 姓名 | 吴飞 |
| 出生年月 | 1980年5月 |
| 单位 | 武汉大学人民医院骨四科 |
| 所属学科 | 临床医学-外科学 |
| 职务、职称及头衔 | 科主任，主任医师，硕士生导师 |
| renminwufei@163.com | |
| 联系方式 | 027-88041911转82061或13554293389 |
| 研究方向 |
1.骨科创伤及显微修复 2.生物医用材料基础与应用 3.骨肿瘤 |
| 个人简介 | 主要从事骨科疾病的诊治与科研工作，擅长四肢骨创伤及显微外科修复，损伤肢体的再植与再造及脊柱的微创手术，担任《骨科临床诊疗规范与新进展》副主编，先后主持国家自然基金青年项目、湖北省卫生厅青年科技人才项目、湖北省科技厅研究项目、武汉市卫计委研究项目、武汉市医学骨干人才培养项目等8项。发表SCI论文13篇，其中以第一作者发表9篇，在国内外相关专业期刊发表论著26篇。 |
| 学术任职与荣誉 |
武汉大学人民医院骨四科科主任 武汉大学人民医院骨外科研究所副主任 湖北省医学会骨外科分会委员（创伤学组秘书） 湖北省医学会创伤外科分会委员 湖北省医学会显微外科分会常委 湖北省运动人体科学研究会骨科专业委员会常委 亚太足踝外科医师协会中国区委员 湖北省老年学学会骨质疏松专业青年委员 湖北省生物医学工程学会骨生物材料与组织工程专业青年委员 湖北省生物医学工程学会人工关节专业青年委员 |
| 教育履历 |
1998-09
2003-07 武汉大学医学院临床医学专业本科生 获学士学位 2003-09 2005-07 武汉大学第一临床学院外科学硕士研究生 获硕士学位 2008-09 2011-07 武汉大学第二临床学院外科学博士研究生 获博士学位 |
| 工作履历 |
2005.08-2012.12 华中科技大学同济附属普爱医院;主治医师 2012.09-2013.08 北京积水潭医院进修学习 2013.01-2014.10 美国哈佛大学附属麻省总医院骨外科访问学者 2014.10至今武汉大学人民医院骨外四科；科室主任，骨外科研究室副主任 |
| 成果获奖 |
《纳米仿生化神经支架的研发及制造》金奖（武汉大学首届创新创业投资峰会，武汉大学，2019，第一） 《纳米仿生化神经支架的研发及制造》优秀创新奖（湖北省教科文卫体系统第二届职工创业创新比赛暨湖北省“工友杯”职工创业创新大赛，湖北省总工会，2019，第一） 《局部使用丙戊酸钠促进鼠损伤坐骨神经修复与再生的机制研究》武汉市科技进步奖三等奖（排名第一） |
| 代表性论著 |
1.Na
Yao, Ran Meng, Fei Wu,（并列第一）,
et al. Oxygen-Vacancy-Induced CeO2/Co4N heterostructures toward enhanced
pH-Universal hydogen evolution reactions. Applied Catalysis B:Environmental
2020, 277 : 119282. (IF:16.68,一区) 2.Peng yu Han, TanTan, Fei Wu（并列第一）, et al. Nickel-iron borate coated nickel-iron boride hybrid for highly stable and active oxygen evolution electrocatalysis. Chinese Chemical Letters 2020, 31: 2469-2472. (IF:3.84，二区) 3.Fei Wu , Wei Huang , Yue Yang. MiR-155-5p regulates mesenchymal stem cell osteogenesis and proliferation via targeting GSK3B in steroid-associated osteonecrosis. Cell Biol Int 2020. doi: 10.1002/cbin.11470. Online ahead of print. (IF:2.57) 4.Fei Wu, Jing Jiao, Feng Liu, et al. Hypermethylation of Frizzled1 is associated with Wnt/β-catenin signaling inactivation in mesenchymal stem cells of patients with steroid-associated osteonecrosis. Exp Mol Med 2019, 51(2):1-9. (IF:5.42,二区) 5.Zhibo Sun, Fei Wu（通讯作者）, Yue Yang1, et al.MiR-144-3p Inhibits BMSC Proliferation and Osteogenic Differentiation Via Targeting FZD4 in Steroid-Associated Osteonecrosis. Current Pharmaceutical Design 2019, 25: 4806-4812. (IF:2.75) 6.Fei Wu, Xiaofang Shen, Kyle R. Eberlin, Zhibo Sun, Xiao Zhou, Mingyu Xue. The use of arteriovenous anastomosis for venous drainage during Tamai zone I fingertip replantation. Injury 2018; 49(6):1113-1118. (IF:2.19) 7.Fei Wu, Aixi Yu, Danmou Xing, Wusheng Kan, Zhengren Peng, Ting Rao. The mood stabilizer valproic acid induces proliferation and myelination of rat Schwann cells. Neuroscience Research 2011;70:383-390. (IF:2.20) 8.Fei W, Danmou X, Zhengren P, Ting R. Enhanced rat sciatic nerve regeneration through silicon tubes implanted with Valproic acid. J Reconstr Microsurg 2008;24:267-276. (IF:1.43) 9.Wu Fei, Xing Danmou, Ren Dong, et al. Free vascularized medial femoral condyle corticocancellous graft in treating recalcitrant upper extremity non-unions. J Reconstr Microsurg 2015;31(2):124-131. (IF:1.43) 10.Rivlin M, Fei W, Mudgal CS. Bennett Fracture. J Hand Surg Am 2015;40(8):1667-1668. (IF:1.64) 11.Kachooei AR, Rivlin M, Wu F, et al. Intraoperative Physical Examination for Diagnosis of Interosseous Ligament Rupture-Cadaveric Study. J Hand Surg Am 2015;40(9):1785-1790. (IF:1.64) 12.Ting Rao, Fei Wu（通讯作者）, Danmou Xing, et al. Effects of Valproic Acid on Axonal Regeneration and Recovery of Motor Function after Peripheral Nerve Injury in the Rat. Archieves of Bone and Joint Surgery 2014;2:17-23. 13.杨越，等，吴飞（通讯）.新型冠状病毒肺炎疫情下创伤显微骨科诊疗行为的建议和策略.中华创伤骨科杂志2020;2:120-124. 14.吴飞,贾婷,杨越,等.丙戊酸诱导鼠脂肪源性干细胞向许旺细胞分化的实验研究.中华显微外科杂志2018;41(4):31-35. 15.吴飞,饶婷,李亚明,等.新型纳米材料乳酸-羟基乙酸-L-赖氨酸多肽接枝聚/聚乳酸/纳米羟基磷灰石/丙戊酸神经导管促进大鼠周围神经再生的研究.中华实验外科杂志2015;32:1595-1598. 16.饶婷,吴飞（通讯作者），程帆，等.新型复合材料PRGD/PDLLA/VPA神经导管促进大鼠周围神经再生的实验研究.中华显微外科杂志2015;38:367-371. 17.吴飞,饶婷,李亚明,等.骨又生移植结合钢板内固定治疗上肢骨不连.武汉大学学报（医学版）2016;37:1-4. 18.吴飞，邓明，杨越，等.复合脂肪源性干细胞的VPA/PRGD组织工程神经修复大鼠坐骨神经缺损的实验研究.中华显微外科杂志2017;40:353-357. 19.吴飞，李亚明，张弩，等. BlauthⅤ型拇发育不良的手指拇化治疗.武汉大学学报（医学版）2018；1:1-3. 20.吴飞,喻爱喜，邢丹谋，等.重组人骨形态发生蛋白-2对鼠雪旺细胞增殖及生长相关蛋白GAP-43表达的影响.中华实验外科杂志2011;28:1553-1558. |
| Name | WU FEI |
| Date of birth | May，1980 |
| Department | Department of Orthopedics，Renmin Hospital,Wuhan University. |
| Title | Director, Professor, doctoral tutor |
| renminwufei@163.com | |
| TEL | 027-88041911-820611 or 13554293389 |
| Research Direction |
1.Orthopaedic
trauma and microrepair 2.Fundamentals and applications of biomedical materials 3.Bone tumors |
| Personal Profile | He is mainly engaged in the diagnosis and treatment of orthopaedic diseases and the scientific research work, has been awarded 8 items for the National Natural Science Foundation, provincial science and Technology Department, the Provincial Education Commission and the Provincial Health Department. He has published 13 SCI papers, of which 9 have been published as the first author, and 26 papers in related professional journals at home and abroad. |
| Selected Publications |
1.Na
Yao, Ran Meng, Fei Wu,（并列第一）,
et al. Oxygen-Vacancy-Induced CeO2/Co4N heterostructures toward enhanced
pH-Universal hydogen evolution reactions. Applied Catalysis B:Environmental
2020, 277 : 119282. (IF:16.68,一区) 2.Peng yu Han, TanTan, Fei Wu（并列第一）, et al. Nickel-iron borate coated nickel-iron boride hybrid for highly stable and active oxygen evolution electrocatalysis. Chinese Chemical Letters 2020, 31: 2469-2472. (IF:3.84，二区) 3.Fei Wu , Wei Huang , Yue Yang. MiR-155-5p regulates mesenchymal stem cell osteogenesis and proliferation via targeting GSK3B in steroid-associated osteonecrosis. Cell Biol Int 2020. doi: 10.1002/cbin.11470. Online ahead of print. (IF:2.57) 4.Fei Wu, Jing Jiao, Feng Liu, et al. Hypermethylation of Frizzled1 is associated with Wnt/β-catenin signaling inactivation in mesenchymal stem cells of patients with steroid-associated osteonecrosis. Exp Mol Med 2019, 51(2):1-9. (IF:5.42,二区) 5.Zhibo Sun, Fei Wu（通讯作者）, Yue Yang1, et al.MiR-144-3p Inhibits BMSC Proliferation and Osteogenic Differentiation Via Targeting FZD4 in Steroid-Associated Osteonecrosis. Current Pharmaceutical Design 2019, 25: 4806-4812. (IF:2.75) 6.Fei Wu, Xiaofang Shen, Kyle R. Eberlin, Zhibo Sun, Xiao Zhou, Mingyu Xue. The use of arteriovenous anastomosis for venous drainage during Tamai zone I fingertip replantation. Injury 2018; 49(6):1113-1118. (IF:2.19) 7.Fei Wu, Aixi Yu, Danmou Xing, Wusheng Kan, Zhengren Peng, Ting Rao. The mood stabilizer valproic acid induces proliferation and myelination of rat Schwann cells. Neuroscience Research 2011;70:383-390. (IF:2.20) 8.Fei W, Danmou X, Zhengren P, Ting R. Enhanced rat sciatic nerve regeneration through silicon tubes implanted with Valproic acid. J Reconstr Microsurg 2008;24:267-276. (IF:1.43) 9.Wu Fei, Xing Danmou, Ren Dong, et al. Free vascularized medial femoral condyle corticocancellous graft in treating recalcitrant upper extremity non-unions. J Reconstr Microsurg 2015;31(2):124-131. (IF:1.43) 10.Rivlin M, Fei W, Mudgal CS. Bennett Fracture. J Hand Surg Am 2015;40(8):1667-1668. (IF:1.64) 11.Kachooei AR, Rivlin M, Wu F, et al. Intraoperative Physical Examination for Diagnosis of Interosseous Ligament Rupture-Cadaveric Study. J Hand Surg Am 2015;40(9):1785-1790. (IF:1.64) 12.Ting Rao, Fei Wu（通讯作者）, Danmou Xing, et al. Effects of Valproic Acid on Axonal Regeneration and Recovery of Motor Function after Peripheral Nerve Injury in the Rat. Archieves of Bone and Joint Surgery 2014;2:17-23. 13.杨越，等，吴飞（通讯）.新型冠状病毒肺炎疫情下创伤显微骨科诊疗行为的建议和策略.中华创伤骨科杂志2020;2:120-124. 14.吴飞,贾婷,杨越,等.丙戊酸诱导鼠脂肪源性干细胞向许旺细胞分化的实验研究.中华显微外科杂志2018;41(4):31-35. 15.吴飞,饶婷,李亚明,等.新型纳米材料乳酸-羟基乙酸-L-赖氨酸多肽接枝聚/聚乳酸/纳米羟基磷灰石/丙戊酸神经导管促进大鼠周围神经再生的研究.中华实验外科杂志2015;32:1595-1598. 16.饶婷,吴飞（通讯作者），程帆，等.新型复合材料PRGD/PDLLA/VPA神经导管促进大鼠周围神经再生的实验研究.中华显微外科杂志2015;38:367-371. 17.吴飞,饶婷,李亚明,等.骨又生移植结合钢板内固定治疗上肢骨不连.武汉大学学报（医学版）2016;37:1-4. 18.吴飞，邓明，杨越，等.复合脂肪源性干细胞的VPA/PRGD组织工程神经修复大鼠坐骨神经缺损的实验研究.中华显微外科杂志2017;40:353-357. 19.吴飞，李亚明，张弩，等. BlauthⅤ型拇发育不良的手指拇化治疗.武汉大学学报（医学版）2018；1:1-3. 20.吴飞,喻爱喜，邢丹谋，等.重组人骨形态发生蛋白-2对鼠雪旺细胞增殖及生长相关蛋白GAP-43表达的影响.中华实验外科杂志2011;28:1553-1558. |
武汉大学人民医院
湖北省人民医院