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  • 余佳 普外
    科室科研秘书,主任医师,副教授,硕士生导师
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    导师介绍

    姓名 余佳
    出生年月 1982年8月
    单位 武汉大学人民医院肝胆外科
    所属学科 临床医学-外科学
    职务、职称及头衔 科室科研秘书,主任医师,副教授,硕士生导师
    E-mail yogaqq116@whu.edu.cn
    联系方式 027-88041911转81085或18062586860
    研究方向 1.急性胰腺炎胰外脏器损伤的发病机制及防治
    2.肝癌的发病机制及防治
    个人简介 主要从事肝胆胰疾病的诊治与科研工作,主持及参与国家自然科学基金5项、省市校级课题5项。主编及参编规划教材《临床普通外科手术技术》和《实验室技术中的惑与获》,在Materials & Design、Cancer science、Cancer Cell International、Oxidative Medicine and Cellular Longevity、Shock、Pancreas、中华肝胆外科杂志等等杂志上发表论文60余篇,以第一及通信作者发表论文30多篇,其中SCI论文10余篇,影响因子超过50。已协助培养硕士生3名,博士生2名。目前正在培养的硕士生2名。
    学术任职与荣誉 武汉医学会机器人与腔镜外科分会第一届肝胆胰外科学组委员
    湖北省临床肿瘤学会胆胰肿瘤专家委员会委员
    湖北省肝胆疾病学会肝胆诊疗专业委员会委员
    湖北省微循环学会微创肝胆外科专业委员会
    JCTH杂志编委;美国休克学会会员
    教育履历 2001.09-2006.06武汉大学第一临床学院临床医学专业本科生获学士学位
    2007.09-2012.06武汉大学第一临床学院外科学硕士研究生硕博连读
    工作履历 2012.07-2012.11武汉大学人民医院肝胆外科 主治医师 2015.12-2020.7 武汉大学人民医院肝胆外科 副主任医师
    2017.08-2018.08纽约州立大学上州医科大 访问学者
    2021.12-至今武汉大学人民医院肝胆外科 副教授
    2021年12月-至今武汉大学人民医院肝胆外科 主任医师
    成果获奖 1.《妊娠合并重症急性胰腺炎器官损伤及巨噬细胞移动抑制因子在肝损伤中作用研究》2016年获十堰市科学技术进步奖二等奖
    2.《CCL5对乳腺癌侵袭与转移的研究和应用》2010年获湖北省科技进步二等奖
    代表性论著 1. Xin Zhang, Keshuai Dong, Jiacheng Zhang, Tianrui Kuang, Yiyun Luo, Jia Yu, Jinming Yu, Weixing Wang. GNB1 promotes hepatocellular carcinoma progression by targeting BAG2 to activate P38/MAPK signaling [J]. Cancer science. 2023; DOI: 10.1111/cas.15741
    2. Xin Zhang, Hongwei Zhang, Zhibin Liao, Jiacheng Zhang, Huifang Liang, Weixing Wang, Jia Yu, Keshuai Dong. SHC4 promotes tumor proliferation and metastasis by activating STAT3 signaling in hepatocellular carcinoma [J].Cancer Cell International. 2022;22(1):1-14.
    3. Fangfang Dai, Jia Yu, Mengqin Yuan, Zhimin Deng, Yangqing Wang, Yaqi Fan, Hongbing Deng, and Yanxiang Cheng. Enhanced Cellular Compatibility of Chitosan/Collagen Multilayers LBL Modified Nanofibrous Mats[J]. Materials & Design. 2021,205(1):109717-109727.
    4. Yu-pu Hong , Jia Yu , Ying-ru Su, Fang-chao Mei, Man Li, Kai-liang Zhao,Liang Zhao, Wen-hong Deng, Chen Chen, and Wei-xing Wang. High-Fat Diet Aggravates Acute Pancreatitis via TLR4-Mediated Necroptosis and Inflammation in Rats. [J].Oxid Med Cell Longev. 2020; 1-10.
    5. Yu Jia, Ni Lan; Zhang Xiaoyi, Zhang Jing, Abdel-Razek Osama, Wang Guirong. Surfactant Protein D Dampens Lung Injury by Suppressing NLRP3 Inflammasome Activation and NF-κB Signaling in Acute Pancreatitis[J]. Shock, 2019; 51(5): 557-568. 6.Man Li, Jia Yu, Liang Zhao , Fang-chao Mei , Yu Zhou , Yu-pu Hong, Teng Zuo, Wei-xing Wang. Inhibition of Macrophage Migration Inhibitory Factor Attenuates Inflammation and Fetal Kidney Injury in a Rat Model of Acute Pancreatitis in Pregnancy[J].Int Immunopharmacol,2019; 68:106-114.
    7.Yu J, Zuo T, Deng W, Shi Q, Ma P, Chen C, Zhao L, Wang W. Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis[J]. BMC Gastroenterology, 2016; 16(1):81-90. DOI 10.1186/s12876-016-0493-5
    8.Zuo T, Yu J, Wang WX, Zhao KL, Chen C, Deng WH, He XB, Wang P, Shi Q, Guo WY. Mitogen-Activated Protein Kinases Are Activated in Placental Injury in Rat Model of Acute Pancreatitis in Pregnancy[J]. Pancreas, 2016; 45(6): 850-7.
    9.Yu J, Deng W, Wang W, Ding Y, Jin H, Chen C, Chen X, Xiong X, Xu S. Inhibition of poly(ADP-ribose) polymerase protects against acute renal injury in rats with experimental acute pancreatitis induced by sodium taurocholate [J].Pancreas, 2012, 41(8):1299-1305.
    10.Wenhong D, Jia Y, Weixing W, Xiaoyan C, Chen C, Sheng X, Hao J. Zerumbone attenuates the severity of acute necrotizing pancreatitis and pancreatitis-associated liver injury [J].Mediat Inflamm., 2012(6):156507.
    12.Yu J, Xu S, Wang WX, Deng WH, Jin H, Chen XY, Chen C, Sun HT. Changes of inflammation and apoptosis in adrenal gland after experimental injury in rats with acute necrotizing pancreatitis [J].Inflammation, 2012, 35(1):11-22.
    Name Jia Yu
    Date of birth August,1982
    Department Hepatobiliary Department,Renmin Hospital,Wuhan University.
    Title Secretary ofscientific research, Chief Physician, Associate Professor, Master tutor
    Email yogaqq116@whu.edu.cn
    TEL 027-88041911-81085 or 18062586860
    Research Direction 1. The pathogenesis and prevention treatment of extrapancreatic organs damage in acute pancreatitis

    2. The pathogenesis and prevention treatment of hepatocellular carcinoma
    Personal Profile He is mainly engaged in the diagnosis, treatment, and scientific research of Hepatobiliary pancreatic diseases, and has been awarded 5 items for the National Natural Science Foundation, and 5 items from the provincial and municipal science and Technology Department. He was the chief editor and co editor of the planned teaching materials "Clinical General surgery Surgical Technology "and "Puzzles and Gains in Laboratory Technology". Besides, there are more than 60 papers published in magazines such as Materials&Design, Cancer science, Cancer Cell International, Oceanic Medicine and Cellular Longevity, Shock, Pancreas, and the Chinese Journal of Hepatobiliary Surgery, and more than 30 papers were published as the first and corresponding authors, including more than 10 SCI papers with an impact factor of more than 50. By now, he has assisted in educating 3 masters and 2 doctors. At present, there are 2 Masters studying with him.
    Selected Publications 1. Xin Zhang, Keshuai Dong, Jiacheng Zhang, Tianrui Kuang, Yiyun Luo, Jia Yu, Jinming Yu, Weixing Wang. GNB1 promotes hepatocellular carcinoma progression by targeting BAG2 to activate P38/MAPK signaling [J]. Cancer science. 2023; DOI: 10.1111/cas.15741
    2. Xin Zhang, Hongwei Zhang, Zhibin Liao, Jiacheng Zhang, Huifang Liang, Weixing Wang, Jia Yu, Keshuai Dong. SHC4 promotes tumor proliferation and metastasis by activating STAT3 signaling in hepatocellular carcinoma [J].Cancer Cell International. 2022;22(1):1-14.
    3. Fangfang Dai, Jia Yu, Mengqin Yuan, Zhimin Deng, Yangqing Wang, Yaqi Fan, Hongbing Deng, and Yanxiang Cheng. Enhanced Cellular Compatibility of Chitosan/Collagen Multilayers LBL Modified Nanofibrous Mats[J]. Materials & Design. 2021,205(1):109717-109727.
    4. Yu-pu Hong , Jia Yu , Ying-ru Su, Fang-chao Mei, Man Li, Kai-liang Zhao,Liang Zhao, Wen-hong Deng, Chen Chen, and Wei-xing Wang. High-Fat Diet Aggravates Acute Pancreatitis via TLR4-Mediated Necroptosis and Inflammation in Rats. [J].Oxid Med Cell Longev. 2020; 1-10.
    5. Yu Jia, Ni Lan; Zhang Xiaoyi, Zhang Jing, Abdel-Razek Osama, Wang Guirong. Surfactant Protein D Dampens Lung Injury by Suppressing NLRP3 Inflammasome Activation and NF-κB Signaling in Acute Pancreatitis[J]. Shock, 2019; 51(5): 557-568. 6.Man Li, Jia Yu, Liang Zhao , Fang-chao Mei , Yu Zhou , Yu-pu Hong, Teng Zuo, Wei-xing Wang. Inhibition of Macrophage Migration Inhibitory Factor Attenuates Inflammation and Fetal Kidney Injury in a Rat Model of Acute Pancreatitis in Pregnancy[J].Int Immunopharmacol,2019; 68:106-114.
    7.Yu J, Zuo T, Deng W, Shi Q, Ma P, Chen C, Zhao L, Wang W. Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis[J]. BMC Gastroenterology, 2016; 16(1):81-90. DOI 10.1186/s12876-016-0493-5
    8.Zuo T, Yu J, Wang WX, Zhao KL, Chen C, Deng WH, He XB, Wang P, Shi Q, Guo WY. Mitogen-Activated Protein Kinases Are Activated in Placental Injury in Rat Model of Acute Pancreatitis in Pregnancy[J]. Pancreas, 2016; 45(6): 850-7.
    9.Yu J, Deng W, Wang W, Ding Y, Jin H, Chen C, Chen X, Xiong X, Xu S. Inhibition of poly(ADP-ribose) polymerase protects against acute renal injury in rats with experimental acute pancreatitis induced by sodium taurocholate [J].Pancreas, 2012, 41(8):1299-1305.
    10.Wenhong D, Jia Y, Weixing W, Xiaoyan C, Chen C, Sheng X, Hao J. Zerumbone attenuates the severity of acute necrotizing pancreatitis and pancreatitis-associated liver injury [J].Mediat Inflamm., 2012(6):156507.
    12.Yu J, Xu S, Wang WX, Deng WH, Jin H, Chen XY, Chen C, Sun HT. Changes of inflammation and apoptosis in adrenal gland after experimental injury in rats with acute necrotizing pancreatitis [J].Inflammation, 2012, 35(1):11-22.