武汉大学人民医院湖北省人民医院

院内导航

吴智勇 心胸外
科主任，主任医师，硕士生导师

A+ A-

导师介绍

姓名	吴智勇
出生年月	1977年10月
单位	武汉大学人民医院心血管外科
所属学科	临床医学-外科学
职务、职称及头衔	科主任，主任医师，硕士生导师
E-mail	wzy2008@whu.edu.cn
联系方式	027-88041911转82230或 18971490330
研究方向	1.心脏移植的临床与基础研究 2.心血管疾病的微创化治疗
个人简介	从事心血管外科临床工作20余年，常规开展先心病的外科手术和微创介入手术，各种类型的微创小切口瓣膜置换和成形术，房颤外科MAZE4迷宫术，各种类型的主动脉开放、杂交及支架植入术，心脏移植及人工心脏植入手术。主持和参与了多项国家、省部级科研项目，获省部级科技奖励5项。在《Critical Care》、《Scientific Report》等杂志上发表论文50余篇，其中SCI论文10余篇。目前正在培养的硕士生1名。
学术任职与荣誉	中华医学会器官移植分会心脏移植学组委员湖北省医师协会心血管外科分会常委湖北省医学会胸心外科分会委员武汉医学会心血管外科分会副主任委员
教育履历	1996.09-2001.06，张家口医学院临床医学专业本科生，获学士学位 2001.09-2004.06，武汉大学第一临床学院外科学硕士研究生，获硕士学位 2006.09-2011.12，武汉大学第一临床学院外科学博士研究生，获博士学位
工作履历	2004.07-2008.05，武汉大学人民医院心血管外科，住院医师 2008.05-2016.11，武汉大学人民医院心血管外科，主治医师 2014.3-2022.08，武汉大学人民医院,心血管外科，副主任 2016.11-2020.11，武汉大学人民医院心血管外科，副主任医师 2020.11-至今，武汉大学人民医院心血管外科，主任医师 2022.08-至今，武汉大学人民医院心血管外科，主任
成果获奖	1.《主动脉夹层发病基础及复杂升弓部大血管手术技术创新》2015年获湖北省技进步一等奖 2.《复杂升弓部大血管手术技术创新与临床推广应用》2019年获湖北省科技成果推广二等奖
代表性论著	1. Zhiyong Wu(#) (), Rui Hu(#), Cuizhen Zhang(#), Wei Ren, Anfeng Yu , Xiaoyang Zhou(). Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients.Crit Care(IF:6.407). 2020 ,24(1):290. 2. Wu Z (), Wang Z, Wu H, Hu R, Ren W, Hu Z, Chang J.Obesity is a risk factor for preoperative hypoxemia in Stanford A acute aortic dissection.Medicine (IF:1.870). 2020 ,99(11):e19186. 3. Wu Z (), Wang Z, Xu P, Zhang M, Cheng L, Gong B. A Novel Finding: Macrophages Involved in Inflammation Participate in Acute Aortic Dissection Complicated with Acute Lung Injury. Current Molecular Medicine (IF:2.345), 2017;17(8):568-579. 4. Wu Z(), Chang J, Ren W, Hu Z, Li B, Liu H. Bindarit reduces the incidence of acute aortic dissection complicated lung injury through modulating NF-κB pathway. Exp Ther Med (IF:1.28), 2017, 14(3):2613-2618. 5. Wu Z (), Hu Z, Cai X, Ren W, Dai F, Liu H, Chang J, Li B. Interleukin 22 attenuated angiotensin II induced acute ling injury through inhibiting the apoptosis of pulmonary microvascular endothelial cells. Scientific Reports (IF:4.259), 2017, 7(1):2210.doi:10.1038/s41598-017-02056-w. 6. Wu Z(), Liu H, Ren W, Dai F, Chang J, Li B. VE-cadherin involved in the pulmonary microvascular endothelial cell barrier injury induced by angiotensin II through modulating the cellular apoptosis and skeletal rearrangement. Am J Transl Res (IF:3.146), 2016,8(10):4310-4319. 7. Wu Z (), Wang Z, Dai F, Liu H, Ren W, Chang J, Li B. Dephosphorylation of Y685–VE- cadherin involved in pulmonary microvascular endothelial barrier injury induced by angiotensin II. Mediators of Inflammation (IF:3.418), 2016. doi:10.1155/2016/8696481. 8. Wu Z (), Ruan Y, Chang J, Li B, Ren W. Angiotensin II is related to the acute aortic dissection complicated with lung injury through mediating the release of MMP9 from macrophages. Am J Transl Res (IF: 3.146), 2016, 8(3):1426-1436. 9. Wu Z(), Dai F, Ren W, Liu H, Li B, Chang J. Angiotensin II induces apoptosis of human pulmonary microvascular endothelial cells in acute aortic dissection complicated with lung injury patients through modulating the expression of monocyte chemoattractant protein-1. Am J Transl Res (IF:3.146), 2016, 8(1):28-36. 10. Wu ZY(#) (), Yao Y(#), Hu R, Dai FF, Zhang H, Mao ZF. Cyclic adenosine monophosphate protein kinase A signal pathway may be involved in pulmonary aquaporin-5 expression in ischemia/reperfusion rats following deep hypothermia cardiac arrest. Genet Mol Res (IF:0.764), 2016, 15(1). doi: 10.4238/gmr.15017377. 11. Wu ZY(#) (), Wang ZW(#), Hu R, Zhou Z, Li LC, Mao ZF. Role of Nrf2 signal pathway in rats with deep hypothermia ischemia/reperfusion injury undergoing remote postconditioning. Genet Mol Res (IF:0.764), 2015, 14(1): 492-499.

Name	ZHIYONG WU
Date of birth	October 1977
Department	Department of Cardiovascular Surgery, Renmin Hospital of Wuhan University
Title	Director, Chief Physician, Master's Supervisor
Email	wzy2008@whu.edu.cn
TEL	027-88041911-82230 or 18971490330
Research Direction	1. Clinical and basic research of heart transplantation 2. Minimally invasive treatment of cardiovascular disease
Personal Profile	He has been engaged in cardiovascular surgery for more than 20 years, routinely perform surgery and minimally invasive surgery for congenital heart disease, heart valve replacement and repair, MAZE IV, total arch replacement and hybrid repair for aortic dissection, heart transplantation and artificial heart implantation. He has hosted and participated in many national and provincial scientific research projects and won 5 provincial and ministerial awards. Published more than 50 papers in scientific journals such as 《Critical Care》and 《Scientific Report》, currently there is 1 master studying with him.
Selected Publications	1. Zhiyong Wu(#) (), Rui Hu(#), Cuizhen Zhang(#), Wei Ren, Anfeng Yu , Xiaoyang Zhou(). Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients.Crit Care(IF:6.407). 2020 ,24(1):290. 2. Wu Z (), Wang Z, Wu H, Hu R, Ren W, Hu Z, Chang J.Obesity is a risk factor for preoperative hypoxemia in Stanford A acute aortic dissection.Medicine (IF:1.870). 2020 ,99(11):e19186. 3. Wu Z (), Wang Z, Xu P, Zhang M, Cheng L, Gong B. A Novel Finding: Macrophages Involved in Inflammation Participate in Acute Aortic Dissection Complicated with Acute Lung Injury. Current Molecular Medicine (IF:2.345), 2017;17(8):568-579. 4. Wu Z(), Chang J, Ren W, Hu Z, Li B, Liu H. Bindarit reduces the incidence of acute aortic dissection complicated lung injury through modulating NF-κB pathway. Exp Ther Med (IF:1.28), 2017, 14(3):2613-2618. 5. Wu Z (), Hu Z, Cai X, Ren W, Dai F, Liu H, Chang J, Li B. Interleukin 22 attenuated angiotensin II induced acute ling injury through inhibiting the apoptosis of pulmonary microvascular endothelial cells. Scientific Reports (IF:4.259), 2017, 7(1):2210.doi:10.1038/s41598-017-02056-w. 6. Wu Z(), Liu H, Ren W, Dai F, Chang J, Li B. VE-cadherin involved in the pulmonary microvascular endothelial cell barrier injury induced by angiotensin II through modulating the cellular apoptosis and skeletal rearrangement. Am J Transl Res (IF:3.146), 2016,8(10):4310-4319. 7. Wu Z (), Wang Z, Dai F, Liu H, Ren W, Chang J, Li B. Dephosphorylation of Y685–VE- cadherin involved in pulmonary microvascular endothelial barrier injury induced by angiotensin II. Mediators of Inflammation (IF:3.418), 2016. doi:10.1155/2016/8696481. 8. Wu Z (), Ruan Y, Chang J, Li B, Ren W. Angiotensin II is related to the acute aortic dissection complicated with lung injury through mediating the release of MMP9 from macrophages. Am J Transl Res (IF: 3.146), 2016, 8(3):1426-1436. 9. Wu Z(), Dai F, Ren W, Liu H, Li B, Chang J. Angiotensin II induces apoptosis of human pulmonary microvascular endothelial cells in acute aortic dissection complicated with lung injury patients through modulating the expression of monocyte chemoattractant protein-1. Am J Transl Res (IF:3.146), 2016, 8(1):28-36. 10. Wu ZY(#) (), Yao Y(#), Hu R, Dai FF, Zhang H, Mao ZF. Cyclic adenosine monophosphate protein kinase A signal pathway may be involved in pulmonary aquaporin-5 expression in ischemia/reperfusion rats following deep hypothermia cardiac arrest. Genet Mol Res (IF:0.764), 2016, 15(1). doi: 10.4238/gmr.15017377. 11. Wu ZY(#) (), Wang ZW(#), Hu R, Zhou Z, Li LC, Mao ZF. Role of Nrf2 signal pathway in rats with deep hypothermia ischemia/reperfusion injury undergoing remote postconditioning. Genet Mol Res (IF:0.764), 2015, 14(1): 492-499.