陈治标
神外
神经外科副主任兼神经外科三科主任，主任医师、博士生导师
神经外科副主任兼神经外科三科主任，主任医师、博士生导师
导师介绍
| 姓名 | 陈治标 |
| 出生年月 | 1964年10月 |
| 单位 | 武汉大学人民医院神经外科三科 |
| 所属学科 | 临床医学-外科学 |
| 职务、职称及头衔 | 神经外科副主任兼神经外科三科主任，主任医师、博士生导师 |
| chzbiao@126.com | |
| 联系方式 | 027-88041911转81127 |
| 研究方向 |
1.脑血管病的临床与基础研究 2.脑肿瘤的临床与基础研究 |
| 个人简介 | 从事神经外科临床各类疑难重症疾病的诊治，尤其擅长经鼻垂体瘤手术，颅底等深在部位脑肿瘤、颅内复杂动脉瘤及动静脉畸形的显微手术治疗。完成（及在研）国家自然科学基金、省、市基金等课题12项，获得湖北省科技进步一、二、三等奖各1项，发表SCI及中文核心期刊论文60余篇，主译、主编及参编著作4部。已培养硕士生30余名，目前正在培养硕士生3名。 |
| 学术任职与荣誉 | 湖北省神经外科质量控制中心委员及办公室主任、湖北省医师协会神经外科分会副主任委员、湖北省抗癌协会神经肿瘤专业委员会委员、湖北省病理生理学会神经专业委员会理事、中国医促会脑血管专业委员会委员、《中国临床神经外科杂志》编委。 |
| 教育履历 |
1982.9–1987.7,湖北医学院,医学系,学士 1990.9–1993.7,湖北医科大学,第一临床学院神经外科,硕士 2004.9–2008.6,武汉大学,医学院临床医学,博士 |
| 工作履历 |
1987.7-1990.9,湖北医学院,附属第一临床学院,教师 1992.9-1993.11,武汉大学,人民医院,住院医师 1993.11-1998.11,武汉大学,人民医院,主治医师 1998.11-2004.11,武汉大学,人民医院,副主任医师 2004.11-至今,武汉大学,人民医院,主任医师 |
| 成果获奖 |
1.《脑胶质瘤的外科干预策略及侵袭性分子机制研究》2009年获湖北省科技进步二等奖 2.《人脑胶质瘤精准外科手术治疗及其相关发病机制》2017年湖北省科技进步一等奖 |
| 代表性论著 |
1）Liquan Wu*, Fang Wang, Jiang Xu,
Zhibiao Chen*. PTPN2 induced by inflammatory response and oxidative stress
contributed to glioma progression, Journal of Cellular Biochemistry, 2019,
120(11): 19044-19051. 2）Qiang Cai, Qiao Guo, Fan Zhang#, Daofa Sun#, Wenfei Zhang, Baowei Ji, Zhibiao Chen, Shanpinp Mao, Evacuation of chronic and subacute subdural hematoma via transcranial neuroendoscopic approach,Neuropsychiatr Dis Treat., 2019,15;385-390. 3）Qiang Cai, Huaping Zhang, Dong Zhao, Zhaohui Yang, Keqi Hu, Long Wang, Wenfei Zhang, Zhibiao Chen, Qianxue Chen,Analysis of three surgical treatments for spontaneous supratentorial intracerebral hemorrhage,Medicine (Baltimore)., 2017 ,96(43);e8435. 1）Baowei Ji* , Lihua Chen, Qiang Cai , Qiao Guo, Zhibiao Chen*, Du He*. Identification of an 8-miRNA signature as a potential prognostic biomarker for glioma. Peer J. 2020 Sep 28;8:e9943. 2）Liquan Wu*, Fang Wang, Jiang Xu, Zhibiao Chen*. PTPN2 induced by inflammatory response and oxidative stress contributed to glioma progression, Journal of Cellular Biochemistry, 2019, 120(11): 19044-19051. 3）Qiang Cai, Xiangyang Zhang,Long Wang,Shulan Huang, Zhibiao Chen*,Qianxue Chen*, Keyhole approach in the neuroendoscopic treatment for hydrocephalus, Medicine (Baltimore)., 2017 ,96(1); e5823. 4）Qiang Cai, Gang Xu, Junhui Liu, Long Wang, Jun Liu*, Zhibiao Chen*, A modification of intraluminal middle cerebral artery occlusion/reperfusion model for ischemic stroke with laser Doppler flowmetry guidance in mice, Neuropsychiatr Dis Treat., 2016, 12; 2851-2858. 5）Qiang Cai, Long Wang, Gang Deng, Junhui Liu, Qianxue Chen*, Zhibiao Chen*, Systemic delivery to central nervous system by engineered PLGA nanoparticles, Am J Transl Res., 2016, 8(2); 749-64. 6）Cai Q, Wang J, Wang L, Deng G, Chen Q*, Chen Z*,A classification of lesions around interventricular foramen and its clinical value, Int J Clin Exp Pathol., 2015, 8(9); 9950-57. 7）Qiang Cai, Jun Wang, Long Wang, Gang Deng, Qianxue Chen*, Zhibiao Chen*, A classification of lesions around interventricular foramen and its clinical value, Int J Clin Exp Pathol., 2015, 8(9); 9950-7. 8）Qiang Cai, Qiao Guo, Fan Zhang#, Daofa Sun#, Wenfei Zhang, Baowei Ji, Zhibiao Chen, Shanpinp Mao, Evacuation of chronic and subacute subdural hematoma via transcranial neuroendoscopic approach,Neuropsychiatr Dis Treat., 2019,15;385-390. 9）Qiang Cai, Zhiyang Li, Wenju Wang, Baowei Ji, Junhui Liu, Zhibiao Chen, Qianxue Chen, and Shanping Mao. Hemorrhagic stroke treated by transcranial neuroendoscopic approach. Sci Rep. 2021; 11: 11890. 10）Liquan Wu , Haitao Xu , Wenfei Zhang , Zhibiao Chen , Wenlan Li , Wei Ke .Circular RNA circCCDC9 alleviates ischaemic stroke ischaemia/reperfusion injury via the Notch pathway. J Cell Mol Med.24(24):14152-1415. 11）Qiang Cai, Baowei Ji , Zhiyang Li , Wenju Wang , Junhui Liu , Zhibiao Chen . Cerebral Arteriovenous Malformation Treatment by Full Transcranial Neuroendoscopic Approaches. Neuropsychiatr Dis Treat. 2020,16:1899-1905. 12）Qiang Cai, Huaping Zhang, Dong Zhao, Zhaohui Yang, Keqi Hu, Long Wang, Wenfei Zhang, Zhibiao Chen, Qianxue Chen, Analysis of three surgical treatments for spontaneous supratentorial intracerebral hemorrhage,Medicine (Baltimore)., 2017 ,96(43);e8435. 13）Qiang Cai, Wenfei Zhang, Baowei Ji, Xiang Ding, Zhibiao Chen, Qianxue Chen, Basal ganglion hematoma evacuation and clipping of middle cerebral artery aneurysm by neuroendoscopy: A case report, Medicine (Baltimore)., 2018 ,97; e606. 14）Liang Meng , Qianxue Chen , Zhibiao Chen , Yuefei Wang , Baowei Ji , Xiaoxiang Yu , Jian Ge .microRNA-1471 suppresses glioma cell growth and invasion by repressing metadherin expression. Int J Clin Exp Pathol. 2018, 11(12):5909-5915. 15）Zaiming Liu , Qianxue Chen , Zhibiao Chen , Junmin Wang , Daofeng Tian , Long Wang , Baohui Liu , Shenqi Zhang . Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy. Arq Neuropsiquiatr. 2019,77(6): 375-380. 16）Ling Zhu , Xiaoyu Liu , Daniel P Nemeth , Damon J DiSabato , Kristina G Witcher , Daniel B Mckim , Braedan Oliver , Xi Le , Gowthami Gorantla , Olimpia Berdysz , Jiaoni Li , Aishwarya D Ramani , Zhibiao Chen , Dongcheng Wu , Jonathan P Godbout , Ning Quan ..Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signaling. Brain Behav Immun. 2019,81:292-304. 17）Qiang Cai , Qiao Guo , Zhiyang Li , Wenju Wang , Wenfei Zhang , Baowei Ji , Zhibiao Chen , Jun Liu.Minimally invasive evacuation of spontaneous supratentorial intracerebral hemorrhage by transcranial neuroendoscopic approach. Neuropsychiatr Dis Treat. 2019 ,11;15:919-925. 18）Qiang Cai , Qiao Guo, Wenfei Zhang, Baowei Ji, Zhibiao Chen, Qianxue Chen. Surgical treatment of a posterior inferior cerebellar artery aneurysm via transcranial neuroendoscopic approach: A case report. Medicine (Baltimore). 2019 ,98(17): e15304. 19）Qiang Cai, Qiao Guo, Wenfei Zhang, Baowei Ji, Zhibiao Chen, Qianxue Chen. Extradural anterior clinoidectomy and aneurysm clipping using transcranial neuroendoscopic approach: A case report. Medicine (Baltimore). 2019,98 (17) :e15288. 20）Zai-Ming Liu, Qian-Xue Chen, Zhi-Biao Chen, Dao-Feng Tian 1, Ming-Chang Li, Jun-Min Wang, Long Wang, Bao-Hui Liu, Shen-Qi Zhang, Fei Li, Hui Ye, Long Zhou. RIP3 deficiency protects against traumatic brain injury (TBI) through suppressing oxidative stress, inflammation and apoptosis: Dependent on AMPK pathway. Biochem Biophys Res Commun. 2018,499(2):112-119. |
| Name | ZhiBiao Chen |
| Date of birth | October，1964 |
| Department | Neurosurgery Department，Renmin Hospital,Wuhan University. |
| Title | Director, Professor, Doctor tutor |
| chzbiao@126.com | |
| TEL | 027-88041911-81127 |
| Research Direction |
1.Clinical
and basic research of cerebrovascular disease 2. Clinical and basic research of brain tumor |
| Personal Profile | He is mainly engaged in the diagnosis and treatment of various difficult and severe diseases in neurosurgery, especially in the microsurgery of transnasal pituitary tumor, intracranial tumors, complex intracranial aneurysms and arteriovenous malformations at the depth of skull base.,and has been awarded 12 items for the National Natural Science Foundation, the provincial science and Technology Department, the the municipal fund,etc. Besides,there are more than 60 articles published in SCI and the Chinese core periodical paper and four books are translated, edited and co edited. By now, he has educated 30 masters. At present, there are 3 Masters studying with him. |
| Selected Publications |
1）Baowei Ji* , Lihua Chen, Qiang Cai
, Qiao Guo, Zhibiao Chen*, Du He*. Identification of an 8-miRNA signature as
a potential prognostic biomarker for glioma. Peer J. 2020 Sep
28;8:e9943. 2）Liquan Wu*, Fang Wang, Jiang Xu, Zhibiao Chen*. PTPN2 induced by inflammatory response and oxidative stress contributed to glioma progression, Journal of Cellular Biochemistry, 2019, 120(11): 19044-19051. 3）Qiang Cai, Xiangyang Zhang,Long Wang,Shulan Huang, Zhibiao Chen*,Qianxue Chen*, Keyhole approach in the neuroendoscopic treatment for hydrocephalus, Medicine (Baltimore)., 2017 ,96(1); e5823. 4）Qiang Cai, Gang Xu, Junhui Liu, Long Wang, Jun Liu*, Zhibiao Chen*, A modification of intraluminal middle cerebral artery occlusion/reperfusion model for ischemic stroke with laser Doppler flowmetry guidance in mice, Neuropsychiatr Dis Treat., 2016, 12; 2851-2858. 5）Qiang Cai, Long Wang, Gang Deng, Junhui Liu, Qianxue Chen*, Zhibiao Chen*, Systemic delivery to central nervous system by engineered PLGA nanoparticles, Am J Transl Res., 2016, 8(2); 749-64. 6）Cai Q, Wang J, Wang L, Deng G, Chen Q*, Chen Z*,A classification of lesions around interventricular foramen and its clinical value, Int J Clin Exp Pathol., 2015, 8(9); 9950-57. 7）Qiang Cai, Jun Wang, Long Wang, Gang Deng, Qianxue Chen*, Zhibiao Chen*, A classification of lesions around interventricular foramen and its clinical value, Int J Clin Exp Pathol., 2015, 8(9); 9950-7. 8）Qiang Cai, Qiao Guo, Fan Zhang#, Daofa Sun#, Wenfei Zhang, Baowei Ji, Zhibiao Chen, Shanpinp Mao, Evacuation of chronic and subacute subdural hematoma via transcranial neuroendoscopic approach,Neuropsychiatr Dis Treat., 2019,15;385-390. 9）Qiang Cai, Zhiyang Li, Wenju Wang, Baowei Ji, Junhui Liu, Zhibiao Chen, Qianxue Chen, and Shanping Mao. Hemorrhagic stroke treated by transcranial neuroendoscopic approach. Sci Rep. 2021; 11: 11890. 10）Liquan Wu , Haitao Xu , Wenfei Zhang , Zhibiao Chen , Wenlan Li , Wei Ke .Circular RNA circCCDC9 alleviates ischaemic stroke ischaemia/reperfusion injury via the Notch pathway. J Cell Mol Med.24(24):14152-1415. 11）Qiang Cai, Baowei Ji , Zhiyang Li , Wenju Wang , Junhui Liu , Zhibiao Chen . Cerebral Arteriovenous Malformation Treatment by Full Transcranial Neuroendoscopic Approaches. Neuropsychiatr Dis Treat. 2020,16:1899-1905. 12）Qiang Cai, Huaping Zhang, Dong Zhao, Zhaohui Yang, Keqi Hu, Long Wang, Wenfei Zhang, Zhibiao Chen, Qianxue Chen, Analysis of three surgical treatments for spontaneous supratentorial intracerebral hemorrhage,Medicine (Baltimore)., 2017 ,96(43);e8435. 13）Qiang Cai, Wenfei Zhang, Baowei Ji, Xiang Ding, Zhibiao Chen, Qianxue Chen, Basal ganglion hematoma evacuation and clipping of middle cerebral artery aneurysm by neuroendoscopy: A case report, Medicine (Baltimore)., 2018 ,97; e606. 14）Liang Meng , Qianxue Chen , Zhibiao Chen , Yuefei Wang , Baowei Ji , Xiaoxiang Yu , Jian Ge .microRNA-1471 suppresses glioma cell growth and invasion by repressing metadherin expression. Int J Clin Exp Pathol. 2018, 11(12):5909-5915. 15）Zaiming Liu , Qianxue Chen , Zhibiao Chen , Junmin Wang , Daofeng Tian , Long Wang , Baohui Liu , Shenqi Zhang . Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy. Arq Neuropsiquiatr. 2019,77(6): 375-380. 16）Ling Zhu , Xiaoyu Liu , Daniel P Nemeth , Damon J DiSabato , Kristina G Witcher , Daniel B Mckim , Braedan Oliver , Xi Le , Gowthami Gorantla , Olimpia Berdysz , Jiaoni Li , Aishwarya D Ramani , Zhibiao Chen , Dongcheng Wu , Jonathan P Godbout , Ning Quan ..Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signaling. Brain Behav Immun. 2019,81:292-304. 17）Qiang Cai , Qiao Guo , Zhiyang Li , Wenju Wang , Wenfei Zhang , Baowei Ji , Zhibiao Chen , Jun Liu.Minimally invasive evacuation of spontaneous supratentorial intracerebral hemorrhage by transcranial neuroendoscopic approach. Neuropsychiatr Dis Treat. 2019 ,11;15:919-925. 18）Qiang Cai , Qiao Guo, Wenfei Zhang, Baowei Ji, Zhibiao Chen, Qianxue Chen. Surgical treatment of a posterior inferior cerebellar artery aneurysm via transcranial neuroendoscopic approach: A case report. Medicine (Baltimore). 2019 ,98(17): e15304. 19）Qiang Cai, Qiao Guo, Wenfei Zhang, Baowei Ji, Zhibiao Chen, Qianxue Chen. Extradural anterior clinoidectomy and aneurysm clipping using transcranial neuroendoscopic approach: A case report. Medicine (Baltimore). 2019,98 (17) :e15288. 20）Zai-Ming Liu, Qian-Xue Chen, Zhi-Biao Chen, Dao-Feng Tian 1, Ming-Chang Li, Jun-Min Wang, Long Wang, Bao-Hui Liu, Shen-Qi Zhang, Fei Li, Hui Ye, Long Zhou. RIP3 deficiency protects against traumatic brain injury (TBI) through suppressing oxidative stress, inflammation and apoptosis: Dependent on AMPK pathway. Biochem Biophys Res Commun. 2018,499(2):112-119. |
武汉大学人民医院
湖北省人民医院