杜贤进
重症
重症医学科Ⅰ科副主任，主任医师，副教授，硕士生导师
重症医学科Ⅰ科副主任，主任医师，副教授，硕士生导师
导师介绍
| 姓名 | 杜贤进 |
| 出生年月 | 1983年9月 |
| 单位 | 武汉大学人民医院重症医学科 |
| 所属学科 | 临床医学-重症医学 |
| 职务、职称及头衔 | 重症医学科I科副主任，主任医师，副教授，硕士生导师 |
| dxj3410@163.com | |
| 联系方式 | 13476267260 |
| 研究方向 |
1.急危重症基础与临床 2.脓毒症基础与临床 |
| 个人简介 | 纽约州立大学访问学者，主要从事急危重症医学的临床、科研与教学工作，主持国家自然科学基金、省科技厅、省教育厅、武汉大学教学改革、武汉大学自主研究项目等课题7项。副主译临床专著1部，参编专著1部，以第一作者（或通讯作者）发表论文30余篇，其中SCI论文10余篇，获湖北省科技进步二等奖一项（排名第四）。武汉大学人民医院第五轮青年重点人才，武汉大学人民医院“人民抗疫英模”，连续多年被评为武汉大学人民医院优秀共产党员、先进工作者、住院医师规范化培训优秀带教老师、医德医风先进个人等荣誉称号。目前正在培养的硕士生2名。 |
| 学术任职与荣誉 |
中华医学会急诊医学分会创伤学组委员 中华医学会急诊医学分会临床技术培训学组委员 中国医师协会急诊医师分会急诊外科学组委员 中国医师协会急诊医师分会国际合作与交流工作委员会委员 中国医学救援协会灾害救援分会青年学组委员 中国医疗保健国际交流促进会急诊急救分会委员 湖北急诊专科医联体副秘书长 湖北省急危重症移动ECMO支持中心专家委员会副主任委员 湖北省生物免疫学会医学科普专业委员会委员 湖北省红十字会应急救护专家指导委员会委员 武汉医师协会急诊医师分会委员 武汉市医学会急诊医学分会委员 |
| 教育履历 |
2000.09-2005.06
武汉大学医学院临床医学专业本科生 获学士学位 2005.09-2010.06 武汉大学第一临床学院外科学博士研究生 获博士学位 |
| 工作履历 |
2010.07-2010.12
武汉大学人民医院 医师 2011.01-2016.11 武汉大学人民医院 主治医师 2014.10-2015.10 SUNY Upstate Medical University;马里兰大学医学院休克创伤中心访问学者 2016.12-2020.11 武汉大学人民医院 副主任医师 2018.10-2020.08 武汉大学人民医院急诊科 急诊科副主任 2020.12-至今 武汉大学人民医院 主任医师 2020.08-至今 武汉大学人民医院重症医学科I科 重症医学科I科副主任 |
| 成果获奖 |
1．2016.12
选择性激动肾上腺素能受体在心肺复苏及复苏后脏器保护中的应用与机制探讨
湖北省科技进步二等奖（排名第4） 2．2015.06 获美国休克学会第38届年会,New Investigators Travel Award美国休克学会 3．2017.12 《以多学科协作为导向的以问题为基础教学方法在急诊医学教学中的应用》获得2016年度医学教育和医学管理百篇优秀论文评选二等奖 中华医学会医学教育分会，中国高等教育学会医学教育专业委员会 排名第1 |
| 代表性论著 |
1．Wu M,Du
X, Gu R, Wei J: Artificial Intelligence for
Clinical Decision Support in Sepsis. Front Med (Lausanne) ,2021, 8:665464.(通讯作者) 2．Du X, Wei J, Tian D, Yan C, Hu P, Wu X, Yang W. miR-182-5p contributes to intestinal injury in a murine model of Staphylococcus aureus pneumonia-induced sepsis via targeting surfactant protein D. J Cell Physiol, 2020,235(1):563-572. 2．Wu M, Hu N,Du X, Wei J. Application of CRISPR/Cas9 technology in sepsis research. Briefings in functional genomics,2020,19(3):229-234.(通讯作者) 3．Du X, Tian D, Wei J, et al. MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D. Mediators of Inflammation, 2020:1-11. 4．Du X, Wu M, Tian D, Zhou J, Wang L, Zhan L. MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression. PPAR Research, 2020:1-7. 5．Du X, Wei J, Tian D, Yan C, Hu P, Wu X, Yang W, Hu X. NEAT1 promotes myocardial ischemia-reperfusion injury via activating the MAPK signaling pathway. J Cell Physiol, 2019,234(10):18773-18780.. 6．Du X, Lu J, Sha Y. MiR-181a inhibits vascular inflammation induced by ox-LDL via targeting TLR4 in human macrophages. J Cell Physiol, 2018, 233(10):6996-7003. 7．Du X, Meng Q, Sharif A, Abdel-Razek OA, Zhang L, Wang G, Cooney RN. Surfactant Proteins SP-A and SP-D Ameliorate Pneumonia Severity and Intestinal Injury in a Murine Model of Staphylococcus Aureus Pneumonia. Shock, 2016,46(2):164-172. 8．Du X, Hu X, Wei J. Anti-inflammatory effect of exendin-4 postconditioning during myocardial ischemia and reperfusion. Mol Biol Rep. 2014,41(6):3853-3857. 9．Du X, Hu X, Wei J. Postconditioning with rosuvastatin reduces myocardial ischemia-reperfusion injury by inhibiting high mobility group box 1 protein expression. Exp Ther Med, 2014, 7(1):117-120. 10．杜贤进,魏捷,杨卫泽,李文强,吕菁君,王蕊.以多学科协作治疗为导向的以问题为基础学习教学方法在急诊医学教学中的应用.中华医学教育杂志,2016,36(5):712-714. |
| Name | XIANJIN DU |
| Date of birth | SEPTEMBER，1983 |
| Department | Department of Critical Care Medicine，Renmin Hospital, Wuhan University |
| Title | Vice Director，Vice Professor , Senior doctor , Master tutor, |
| dxj3410@163.com | |
| TEL | 13476267260 |
| Research Direction |
1.
The protection of intestinal barrier function in sepsis 2. Basic and clinical research of acute and severe diseases |
| Personal Profile | He was a visiting scholar at the State University of New York, mainly engaged in the clinical, scientific research and teaching in Emergency Medicine and Critical care medicine, and presided over 7 grants including 1 National Natural Science Foundation of China grant, provincial department of science and technology, provincial department of education, teaching reform of Wuhan University, and independent research of Wuhan University. He has translated 1 clinical monograph and participated in the compilation of 1 monograph. He has published more than 30 papers as the first author (or corresponding author), including more than 10 SCI papers, and won the second prize of science and technology progress in Hubei Province (ranking the fourth).He has been awarded several honorary titles such as excellent communist party member, advanced worker, advanced individual of medical ethics and medical ethics of people's hospital of Wuhan university. |
| Selected Publications |
1．Wu M,Du
X, Gu R, Wei J: Artificial Intelligence for
Clinical Decision Support in Sepsis. Front Med (Lausanne) ,2021, 8:665464.(通讯作者) 2．Du X, Wei J, Tian D, Yan C, Hu P, Wu X, Yang W. miR-182-5p contributes to intestinal injury in a murine model of Staphylococcus aureus pneumonia-induced sepsis via targeting surfactant protein D. J Cell Physiol, 2020,235(1):563-572. 2．Wu M, Hu N,Du X, Wei J. Application of CRISPR/Cas9 technology in sepsis research. Briefings in functional genomics,2020,19(3):229-234. (通讯作者) 3．Du X, Tian D, Wei J, et al. MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D. Mediators of Inflammation, 2020:1-11. 4．Du X, Wu M, Tian D, Zhou J, Wang L, Zhan L. MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression. PPAR Research, 2020:1-7. 5．Du X, Wei J, Tian D, Yan C, Hu P, Wu X, Yang W, Hu X. NEAT1 promotes myocardial ischemia-reperfusion injury via activating the MAPK signaling pathway. J Cell Physiol, 2019,234(10):18773-18780.. 6．Du X, Lu J, Sha Y. MiR-181a inhibits vascular inflammation induced by ox-LDL via targeting TLR4 in human macrophages. J Cell Physiol, 2018, 233(10):6996-7003. 7．Du X, Meng Q, Sharif A, Abdel-Razek OA, Zhang L, Wang G, Cooney RN. Surfactant Proteins SP-A and SP-D Ameliorate Pneumonia Severity and Intestinal Injury in a Murine Model of Staphylococcus Aureus Pneumonia. Shock, 2016,46(2):164-172. 8．Du X, Hu X, Wei J. Anti-inflammatory effect of exendin-4 postconditioning during myocardial ischemia and reperfusion. Mol Biol Rep. 2014,41(6):3853-3857. 9．Du X, Hu X, Wei J. Postconditioning with rosuvastatin reduces myocardial ischemia-reperfusion injury by inhibiting high mobility group box 1 protein expression. Exp Ther Med, 2014, 7(1):117-120. 10．杜贤进,魏捷,杨卫泽,李文强,吕菁君,王蕊.以多学科协作治疗为导向的以问题为基础学习教学方法在急诊医学教学中的应用.中华医学教育杂志,2016,36(5):712-714. |
武汉大学人民医院
湖北省人民医院