姓名 | 李新 |
出生年月 | 1975年12月 |
单位 | 武汉大学人民医院妇产科 |
所属学科 | 临床医学-妇产科学 |
职务、职称及头衔 | 副教授,主任医师,博士生导师 |
xin.li@whu.edu.cn,lixinwhu@189.cn | |
联系方式 | 15307198388 |
研究方向 |
1.妇科肿瘤:主要研究妇科肿瘤发生发展的分子机制及分子诊疗 2.卵巢癌靶向治疗:主要研究卵巢癌化疗耐药的逆转、靶向分子药物设计与实验研究 |
个人简介 | 主要从事妇科疾病的诊治与科研工作,妇科肿瘤的早期诊断及精准靶向、微创治疗。主持国家自然科学基金面上项目2项、主持国家重点研发计划项目子课题1项、参与国家自然科学基金研究项目5项、主持湖北省自然科学基金面上项目1项,武汉大学教学改革项目2项,2023年获批武汉大学教学项目2项。以第一作者/通讯作者发表SCI论文三十余篇,统计源论文5篇;参编专著5部,总影响因子超过100。目前指导硕士生4名,已培养硕士生2名。 |
学术任职与荣誉 | 中国医疗保健国际交流促进会生殖及微创学组委员、湖北省抗癌协会妇瘤专业委员会青年副主任委员、湖北省临床肿瘤学会妇科肿瘤专业委员会常委、湖北省预防医学会妇科疾病专委会宫腔镜学组副组长、中国中药协会女性生殖健康药物研究专业委员会委员、湖北省医学会妇科肿瘤分会委员、武汉市机器人协会妇科手术分会委员 |
教育履历 |
1993.09-1998.06武汉大学医学院临床医学专业本科获学士学位 1999.09-2002.06武汉大学第一临床学院妇产科硕士研究生获硕士学位 2012.09-2016.06武汉大学第一临床学院妇产科博士研究生获博士学位 |
工作履历 |
2002.07-2005.12武汉大学人民医院妇产科住院医师 2006.01-2016.11武汉大学人民医院妇产科主治医师 2009.09-2011.02美国杜克大学研修(1年) 2016.12-2021.11武汉大学人民医院妇产科副主任医师 2017.12-至今武汉大学人民医院妇产科副教授 2021.11-至今武汉大学人民医院妇产科主任医师 |
成果获奖 |
1.参与项目《盆底功能障碍性疾病的基础与临床研究》2018年获湖北省科技进步一等奖 2.参与项目《盆底功能障碍性疾病的发病机制及治疗研究》2009年获湖北省科技进步一等奖、武汉市科技进步二等奖 3.2014年全国妇幼健康技能竞赛个人单项奖,湖北省妇幼健康技能竞赛第一名、一等奖 4.2014年获湖北省五一劳动奖章;湖北省女职工建功立业标兵称号 |
代表性论著 |
1.Chen
C, Xu J, Ruan L, Zhao H, Li X*, Shi X. DNA origami frame filled with two
types of single-stranded tiles. Nanoscale. 2022;14(14):5340-5346. 2.Chen C, Chen X, Li X*, Shi X. DNA computing for gastric cancer analysis and functional classification. Front Genet. 2022;13:1064715 3.Ruan L, Han L, Li X*, et al. Computable structured aptamer for targeted treatment of ovarian cancer. Front Genet. 2023;14:1170260. 4.Chen C, Lin T, Ma M, Shi X, Li X*. Programmable and scalable assembly of a flexible hexagonal DNA origami. Nanotechnology. 2021;33(10):10.1088/1361-6528/ac2768. 5.Ruan L, Li X*. Applications of Aptamers in the Diagnosis and Treatment of Ovarian Cancer: Progress From 2016 to 2020. Front Genet. 2021;12:683542. 6.Gu M, He T, Yuan Y, Duan S, Li X*, Shen C. Single-Cell RNA Sequencing Reveals Multiple Pathways and the Tumor Microenvironment Could Lead to Chemotherapy Resistance in Cervical Cancer. Front Oncol. 2021;11:753386. 7.Sun G, Chen C, Li X, Hong S, Gu C, Shi X. Rapid microRNA detection method based on DNA strand displacement for ovarian cancer cells. J Cancer. 2023;14(5):707-716 |
Name | Xin Li |
Date of birth | Dec.1975 |
Department | Gynecology,Renmin Hospital,Wuhan University. |
Title | Director physician, Associate Professor, doctoral tutor |
xin.li@whu.edu.cn,lixinwhu@189.cn | |
TEL | 15307198388 |
Research Direction |
1.
Gynecological tumor: research on the molecular mechanism and molecular
diagnosis and treatment of gynecological tumors 2. Precise targeted therapy of ovarian cancer: mainly research on reversal of chemotherapy resistance of ovarian cancer and molecular intelligent drug design and experimental research |
Personal Profile | She is mainly engaged in the diagnosis and treatment of gynecological diseases and scientific research, early diagnosis of gynecological tumors and precise targeted and minimally invasive treatment. She has presided over 2 top-level projects of National Natural Science Foundation of China (NSFC), 1 sub-project of National Key Research and Development Program of China (NKRP), participated in 5 research projects of NSFC, 1 top-level project of Hubei Provincial Natural Science Foundation of China (NNSF), 2 projects of Wuhan University Teaching Reform Program, and 2 Wuhan University Teaching Programs in 2023 approved by Wuhan University. He has published more than 30 SCI papers as the first author/corresponding author, and 5 statistical source papers; she has co-edited 5 monographs, with a total impact factor of more than 100, and she is currently supervising 4 master's degree students, and has trained 2 master's degree students. |
Selected Publications |
1.Chen
C, Xu J, Ruan L, Zhao H, Li X*, Shi X. DNA origami frame filled with two
types of single-stranded tiles. Nanoscale. 2022;14(14):5340-5346. 2.Chen C, Chen X, Li X*, Shi X. DNA computing for gastric cancer analysis and functional classification. Front Genet. 2022;13:1064715 3.Ruan L, Han L, Li X*, et al. Computable structured aptamer for targeted treatment of ovarian cancer. Front Genet. 2023;14:1170260. 4.Chen C, Lin T, Ma M, Shi X, Li X*. Programmable and scalable assembly of a flexible hexagonal DNA origami. Nanotechnology. 2021;33(10):10.1088/1361-6528/ac2768. 5.Ruan L, Li X*. Applications of Aptamers in the Diagnosis and Treatment of Ovarian Cancer: Progress From 2016 to 2020. Front Genet. 2021;12:683542. 6.Gu M, He T, Yuan Y, Duan S, Li X*, Shen C. Single-Cell RNA Sequencing Reveals Multiple Pathways and the Tumor Microenvironment Could Lead to Chemotherapy Resistance in Cervical Cancer. Front Oncol. 2021;11:753386. 7.Sun G, Chen C, Li X, Hong S, Gu C, Shi X. Rapid microRNA detection method based on DNA strand displacement for ovarian cancer cells. J Cancer. 2023;14(5):707-716 |