王卫星
普外
武汉大学人民医院普外科学科带头人，三级教授，二级主任医师，博士生导师
武汉大学人民医院普外科学科带头人，三级教授，二级主任医师，博士生导师
导师介绍
| 姓名 | 王卫星 |
| 出生年月 | 1960年6月 |
| 单位 | 武汉大学人民医院普外科 |
| 所属学科 | 临床医学-外科学 |
| 职务、职称及头衔 | 武汉大学人民医院普外科学科带头人，三级教授，二级主任医师，博士生导师 |
| sate.llite@163.com | |
| 联系方式 | 027-88041911转86443 |
| 研究方向 |
1.肝胆胰疾病的基础与临床研究 2.肿瘤代谢与临床静脉营养的研究 |
| 个人简介 | 主要从事肝胆胰外科基础与临床、肿瘤代谢及临床静脉营养的研究。先后主持和参与国家自然科学基金项目6项，省、厅、市级科研项目9项，在国内外学术刊物上发表论文共计300余篇，其中SCI论文50余篇。参编专著8部，教材2部。曾获湖北省科技进步二等奖1项，湖北省高等学校教育成果二等奖1项，武汉市科技进步二等奖2项。已培养博士、硕士百余人，目前正在培养博士10人，硕士13人。 |
| 学术任职与荣誉 |
中国微循环学会常务理事 湖北省微循环学会理事长 湖北省医学会肠外肠内营养分会主任委员 国家健康委医院管理研究所临床营养项目专家工作组特邀专家 湖北省医学会医学教育分会第六届委员会委员 武汉大学消化系统疾病研究所副所长 国务院特殊津贴专家 《微循环学杂志》副主编 《临床外科杂志》副总编辑 《英国药理学杂志》审稿专家 《生理学报》审稿专家 《英国癌症杂志》审稿专家 《国际药物科学杂志》审稿专家 《国际研究》审稿专家 《实验与分子病理学》审稿专家 《 BMJ个案报告》审稿专家 |
| 教育履历 |
1978.09-1983.06湖北医学院（现武汉大学医学部）获学士学位 1987.09-1990.06湖北医学院（现武汉大学医学部）获硕士学位 2000.09-2003.06武汉大学第一临床学院外科学博士研究生获博士学位 |
| 工作履历 |
1983.07-1987.08 武汉大学人民医院住院医师 1992.01-1997.09 武汉大学人民医院主治医师 1997.10-2002.11 武汉大学人民医院副主任医师、副教授 1999.04-2005.04 武汉大学人民医院副院长、党委常委 2005.04-2020.10 武汉大学人民医院党委副书记 2002至今 武汉大学人民医院主任医师 2003至今 武汉大学人民医院教授 2004.06至今 武汉大学人民医院博士生导师 2006.02至今 武汉大学人民医院普外科学科带头人 |
| 成果获奖 |
1.《CCL5对高血压侵袭与转移的研究和应用》2010年湖北省科技进步二等奖和武汉市科技进步二等奖 2.《医学生临床见习及社会实践实验性教育研究》2005年湖北省高等学校教育成果二等奖 3.《肝癌射频热疗的实验和临床应用研究》2006年湖北省科技进步三等奖和武汉市科技进步二等奖 4.《胆结石症患者胆结石，胆汁及血液中氨基酸含量的研究》，《肾局部低温和药物保护性肝癌的实验和临床应用的研究》分别通过省科技厅，省教育厅科学技术成果鉴定，达到国内领先水平。 |
| 代表性论著 |
1．Clinical Characteristics and Risk
Factors for Mortality of COVID-19 Patients With Diabetes in Wuhan, China: A
Two-Center, Retrospective Study. Diabetes Care. 2020,43(7):1382-1391. 2. High-Fat Diet Aggravates Acute Pancreatitis via TLR4-Mediated Necroptosis and Inflammation in Rats. Oxid Med Cell Longev. 2020, 2020:8172714. 3．Apocynin Attenuates Acute Kidney Injury and Inflammation in Rats with Acute Hypertriglyceridemic Pancreatitis. Dig Dis Sci. 2020,65(6):1735-1747. 4. High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis. Mediators Inflamm. 2019, 2019:2512687. 5. Apocynin alleviates lung injury by suppressing NLRP3 inflammasome activation and NF-κB signaling in acute pancreatitis. Int Immunopharmacol. 2019,75:105821. 6. Inhibition of macrophage migration inhibitory factor prevents thyroid dysfunction in pregnant rats with acute pancreatitis. Int Immunopharmacol. 2020,87:106771. 7. Protective Mechanism of MIF Inhibitor ISO-1 on Intrahepatic Bile Duct Cells in Rats with Severe Acute Pancreatitis. Dig Dis Sci. 2020 8. 4-Phenylbutyric Acid Attenuates Endoplasmic Reticulum Stress-Mediated Intestinal Epithelial Cell Apoptosis in Rats with Severe Acute Pancreatitis. Dig Dis Sci. 2019,64(6):1535-1547. 9. Inhibition of macrophage migration inhibitory factor attenuates inflammation and fetal kidney injury in a rat model of acute pancreatitis in pregnancy. Int Immunopharmacol. 2019,68:106-114. 10. Magnesium isoglycyrrhizinate alleviates liver injury in obese rats with acute necrotizing pancreatitis. Pathol Res Pract. 2019,215(1):106-114. 11. SB203580 attenuates acute lung injury and inflammation in rats with acute pancreatitis in pregnancy. Inflammopharmacology. 2019,27(1):99-107. 12. Differential JNK, p38 and ERK response to renal injury in a rat model of acute pancreatitis in pregnancy. Arch Gynecol Obstet. 2018,297(4):933-942. 13. β cells can be generated from cytokeratin 5-positive cells after cerulein-induced pancreatitis in adult mice. Biochem Biophys Res Commun. 2018,496(1):114-119. 14. Inhibition of endoplasmic reticulum stress by 4-phenylbutyric acid prevents vital organ injury in rat acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2018,315(5):G838-G847. 15. NADPH Oxidase Inhibitor Apocynin Attenuates PCB153-Induced Thyroid Injury in Rats. Int J Endocrinol. 2016,2016:8354745. 16. A preliminary study on fetal lung injury in a rat model of acute pancreatitis in pregnancy. Pathol Res Pract. 2017,213(11):1370-1377. 17. Fetal liver injury ameliorated by migration inhibitory factor inhibition in a rat model of acute pancreatitis in pregnancy. J Obstet Gynaecol Res. 2018,44(3):374-383. 18. Hydrogen-Rich Saline Attenuates Acute Hepatic Injury in Acute Necrotizing Pancreatitis by Inhibiting Inflammation and Apoptosis, Involving JNK and p38 Mitogen-Activated Protein Kinase-dependent Reactive Oxygen Species. Pancreas. 2016,45(10):1424-1431. 19. Severity of pancreatitis‑associated intestinal mucosal barrier injury is reduced following treatment with the NADPH oxidase inhibitor apocynin. Mol Med Rep. 2016,14(4):3525-34. 20. Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis. BMC Gastroenterol. 2016 ,16(1):81. |
| Name | WEIXING WANG |
| Date of birth | June, 1960 |
| Department | General Department, Renmin Hospital, Wuhan University. |
| Title | Professor, doctoral tutor |
| sate.llite@163.com | |
| TEL | 027-88041911转86443 |
| Research Direction |
1.
Basic and clinical studies on hepatobiliary and pancreatic diseases. 2.Tumor metabolism and clinical venous nutrition. |
| Personal Profile | He is Mainly engaged in the basic and clinical studies on hepatobiliary and pancreatic diseases, tumor metabolism and clinical venous nutrition. He has presided over or participated in 6 National Natural Science Foundation projects and 9 provincial, departmental or municipal scientific research projects. Besides, there are more than 300 papers in academic journals at home and abroad, including more than 50 SCI papers. He has participated in the compilation of 8 monographs and 2 textbooks. Also he has won 1 Second Prize of Science and Technology Progress of Hubei Province, 1 Second Prize of Education Achievement of Higher Education of Hubei Province, and 2 Second Prize of Science and Technology Progress of Wuhan City. By now, he has educated more than 100 doctors and masters. At present, there are 10 doctors and 13 Masters studying with him. |
| Selected Publications |
1．Clinical Characteristics and Risk
Factors for Mortality of COVID-19 Patients With Diabetes in Wuhan, China: A
Two-Center, Retrospective Study. Diabetes Care. 2020,43(7):1382-1391. 2. High-Fat Diet Aggravates Acute Pancreatitis via TLR4-Mediated Necroptosis and Inflammation in Rats. Oxid Med Cell Longev. 2020, 2020:8172714. 3．Apocynin Attenuates Acute Kidney Injury and Inflammation in Rats with Acute Hypertriglyceridemic Pancreatitis. Dig Dis Sci. 2020,65(6):1735-1747. 4. High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis. Mediators Inflamm. 2019, 2019:2512687. 5. Apocynin alleviates lung injury by suppressing NLRP3 inflammasome activation and NF-κB signaling in acute pancreatitis. Int Immunopharmacol. 2019,75:105821. 6. Inhibition of macrophage migration inhibitory factor prevents thyroid dysfunction in pregnant rats with acute pancreatitis. Int Immunopharmacol. 2020,87:106771. 7. Protective Mechanism of MIF Inhibitor ISO-1 on Intrahepatic Bile Duct Cells in Rats with Severe Acute Pancreatitis. Dig Dis Sci. 2020 8. 4-Phenylbutyric Acid Attenuates Endoplasmic Reticulum Stress-Mediated Intestinal Epithelial Cell Apoptosis in Rats with Severe Acute Pancreatitis. Dig Dis Sci. 2019,64(6):1535-1547. 9. Inhibition of macrophage migration inhibitory factor attenuates inflammation and fetal kidney injury in a rat model of acute pancreatitis in pregnancy. Int Immunopharmacol. 2019,68:106-114. 10. Magnesium isoglycyrrhizinate alleviates liver injury in obese rats with acute necrotizing pancreatitis. Pathol Res Pract. 2019,215(1):106-114. 11. SB203580 attenuates acute lung injury and inflammation in rats with acute pancreatitis in pregnancy. Inflammopharmacology. 2019,27(1):99-107. 12. Differential JNK, p38 and ERK response to renal injury in a rat model of acute pancreatitis in pregnancy. Arch Gynecol Obstet. 2018,297(4):933-942. 13. β cells can be generated from cytokeratin 5-positive cells after cerulein-induced pancreatitis in adult mice. Biochem Biophys Res Commun. 2018,496(1):114-119. 14. Inhibition of endoplasmic reticulum stress by 4-phenylbutyric acid prevents vital organ injury in rat acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2018,315(5):G838-G847. 15. NADPH Oxidase Inhibitor Apocynin Attenuates PCB153-Induced Thyroid Injury in Rats. Int J Endocrinol. 2016,2016:8354745. 16. A preliminary study on fetal lung injury in a rat model of acute pancreatitis in pregnancy. Pathol Res Pract. 2017,213(11):1370-1377. 17. Fetal liver injury ameliorated by migration inhibitory factor inhibition in a rat model of acute pancreatitis in pregnancy. J Obstet Gynaecol Res. 2018,44(3):374-383. 18. Hydrogen-Rich Saline Attenuates Acute Hepatic Injury in Acute Necrotizing Pancreatitis by Inhibiting Inflammation and Apoptosis, Involving JNK and p38 Mitogen-Activated Protein Kinase-dependent Reactive Oxygen Species. Pancreas. 2016,45(10):1424-1431. 19. Severity of pancreatitis‑associated intestinal mucosal barrier injury is reduced following treatment with the NADPH oxidase inhibitor apocynin. Mol Med Rep. 2016,14(4):3525-34. 20. Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis. BMC Gastroenterol. 2016 ,16(1):81. |
武汉大学人民医院
湖北省人民医院