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  • 沈世强 普外
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    导师介绍

    沈世强,男,1957年5月生,籍贯湖北。1994年毕业于日本名古屋大学,医学博士。教授、主任医师。现任外科副主任、普外科主任,博士生导师。主要从事肝胆胰外科临床与实验研究,曾获湖北省科技进步三等奖、武汉市科技进步二等奖,主编专著一部、参编五部,在国内外杂志上发表论文百篇余。已培养博士生十余名、硕士生二十余名;目前正在培养的博士生(含在职)十余名、硕士生4名。

     

    主要研究方向:

    1. 肝癌外科分子生物学

    2. 肝脏保护

     

    学术职务:

    中国医师协会外科医师分会委员

    武汉医学会普通外科学会副主委

    湖北省医学会普通外科学会常务委员

    武汉抗癌研究会会长

    腹部外科杂志副主编

    临床外科杂志常务编委

    中华实验外科杂志编委

    世界胃肠杂志编委

    国际外科学杂志编委

    中国医药导报杂志编委

    World Journal of Gastroenterology 编委

    中华医学杂志英文版及Journal of Surgical Oncology等杂志审稿专家

     

    教育履历:

    1978.03-1982.12 湖北医学院临床医学系本科生

    1986.09-1987.09 湖北医学院外科硕士研究生

    1987.10-1994.03 日本名古屋大学医学部外科博士及博士后

     

    工作履历:

    1983.02-1986.08 武汉市第四医院住院医师 

    1994.04-现在 武汉大学人民医院普外科医师

     

    成果获奖: 

    “肝癌射频热疗的实验和临床应用研究”获湖北省科技进步三等奖,武汉市科技进步二等奖,项目第一完成人。

     

    文代表作:

    1. The Protective Effects of 17β-Estradiol on Hepatic Ischemia-Reperfusion Injury in Rat Model, Associated with Regulation of Heat-Shock Protein Expression. J Surg Res. 2007, 140:67-76

    2. Protective effct of Curcumin against Liver Warm Ischemia-Reperfusion Injury in Rat Model, associated with Regulation of Heat Shock Protein and Antioxidant Enzymes. World J Gastroenterol. 2007, 13(13):1953-1961.

    3. Expression and Clinical significance of NET-1 and PCNA in Hepatocellular carcinoma.Med Oncol.2008,25(3):341-345.

    4. Microvessel damage may play a main role in tumoricidal effect for murine H22 hepatoma cells with hyperthermia in vivo. J Surg Res. 2008,145:97-104.

    5. Intraoperative radiofrequency thermal ablation combined with portal vein infusion Chemotherapy and transarterial chemoembolization for unresectable HCC. Hepatogastroenterology. 2005, 52(65): 1403-1407.

    6. The angimogenic and prognostic implications of VEGF,Ang-1.Ang-2,and MMP-9 for hepatocellular carcinoma with background of hepatitis B virus MEDICAL INCOLOGY,2009,26(3):365-371.

    7. Intratumoural GM-CSF microspheres and CTLA-4 blockade enhance the antiumour immunity induced by thermal ablation in a subcutaneous mutine hepatoma model.INTERNATIONAL JOURNAL OF HYPERTHERMIA,2009,25(5):374-382.

    8. The role of prophyloetic antibiotics in laparoscopic cholecystectomy in preventing postoperatine infection a meta-analysis. Adv   Surg Tech. 2011, 24(4):301-306.

    9. Expression of augmenter of liver regeneration and nuclear faction-kb in human hepatocelluar carcinoma .J Anio Veto Adro .2011,10(4):440-448.

    10.17β-estradiol attenuates reduced-sige hepatic ischemia/heperfusion injury by inhibition apoptosis via mitochodrial in rats.Shock,2012,37(2):183-190. 

    11. Growth inhibition of hepatocellular carcinoma tumor endothelial cells by miR-204-3p and underlying mechanism. World J Gastroenterol, 2014,20(18):5493-5504.

    12. The liver protective effect of methylprednisolone on a new experimental acute-on-chronic liver failure model in rats. Digestive and Liver Disease, 2014, 46(10):928-935. 

    13. Regulation of tumorigenesis and metastasis of hepatocellular carcinoma tumor endothelial cells by microRNA-3178 and underlying mechanism. Biochem Biophys Res Commun.2015,464(3):881-887.

    14. simultaneous hepatectomy and splenectomy versus hepatectomy alone for hepatocellular carcinoma complicated by hypersplenism a meta-analysis. Onco Targets Ther. 2015, 8:2129-37.

    15. Effect of microRNA-1 on hepatocellular carcinoma tumor endothelial cells. World J Gastroenterol. 2015, 21(19):5884-92.