詹丽英
重症
急重症医学中心主任、重症医学科Ⅰ科主任、主任医师、教授、博士生导师
急重症医学中心主任、重症医学科Ⅰ科主任、主任医师、教授、博士生导师
导师介绍
| 姓名 | 詹丽英 |
| 出生年月 | 1971年8月 |
| 单位 | 武汉大学人民医院重症医学科Ⅰ科主任 |
| 所属学科 | 临床医学-重症医学科 |
| 职务、职称及头衔 | 急重症医学中心主任、重症医学科Ⅰ科主任、主任医师、教授、博士生导师 |
| zhanliying@whu.edu.cn | |
| 联系方式 | 027-88041911转81075 |
| 研究方向 | 脓毒症、ARDS |
| 个人简介 | |
| 从事临床工作28年，负责各种疑难危重症的重症监护治疗，擅长各类危重病人的抢救治疗，包括重症感染、脓毒症/脓毒症休克、急性呼吸窘迫综合征、心搏骤停后集束化治疗及器官移植围术期重症监护治疗。现主要研究领域为脓毒症及急性呼吸窘迫综合征发病机制与临床防治。在科室开展多项实用型新业务新技术，重视学科建设中年轻医生、博士研究生、硕士研究生及住培学员思政教育，教育教学业绩突出，主持国家自然科学基金、湖北省自然科学基金项目、湖北省教学研究项目、武汉大学教学改革项目、中央高校基本科研业务项目等课题5项。主编专著1部，以第一作者（或通讯作者）发表SCI论文30余篇，获湖北省科技进步二等奖一项。目前正在培养的硕士研究生5名、博士研究生3名。 | |
| 学术任职与荣誉 | |
| 现任中国医师协会重症医学分会委员，中国病理生理学会重症医学分会委员，湖北省医学会重症医学分会副主任委员，湖北省病理生理学会重症医学分会副主任委员，中国分娩镇痛专家组专家。武昌区政协委员，武汉大学学报（医学版）学术副主编 | |
| 教育履历 | |
|
1990.09-1995.06 湖北医科大学 医疗系 获学士学位 2000.09-2002.06 武汉大学 基础医学院学院 病理生理系 硕士研究生获硕士学位 2005.09-2008.06 武汉大学第一临床学院 外科学博士研究生获博士学位 |
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| 工作履历 | |
|
1995.06-2000.12 武汉大学人民医院麻醉科住院医师 2000.12-2006.12 武汉大学人民医院麻醉科主治医师 2006.12-2012.12 武汉大学人民医院麻醉科副主任医师 2012.12-2020.06 武汉大学人民医院麻醉科主任医师 2015.10-2016.01 意大利Humanitas医学院访问学者 2020.06-至今 武汉大学人民医院重症医学科主任医师 |
|
| 成果获奖 | |
| 高危病人和重症围手术期重要脏器保护的临床应用成果推广二等奖 | |
| 代表性论著 | |
|
1.Song WQ, Wang W, Yang YC, Sun Q, Chen H, Zhang
L, Bu XS, Zhan LY, Xia ZY. Parasternal Intercostal Block Complementation
Contributes to Postoperative Pain Relief in Modified Radical Mastectomy
Employing Pectoral Nerve Block I and Serratus-Intercostal Block: A Randomized
Trial. J Pain Res. 2020 Apr 30;13:865-871. 2.Cui SS, Feng XB, Zhang BH, Xia ZY, Zhan LY. Exendin-4 attenuates pain-induced cognitive impairment by alleviating hippocampal neuroinflammation in a rat model of spinal nerve ligation. Neural Regen Res. 2020 Jul;15(7):1333-1339. 3.Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L. Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation. Yonsei Med J. 2019 Dec;60(12):1195-1202. 4. Zhan LY, Lei SQ, Zhang BH, Li WL, Wang HX, Zhao B, Cui SS, Ding H, Huang QM. Overexpression of miR-381 relieves neuropathic pain development via targeting HMGB1 and CXCR4. Biomed Pharmacother. 2018 Nov;107:818-823. 5. Liying Zhan, Yuan Zhang, Wating Su, Qiongxia Zhang, Rong Chen, Bo Zhao, Wei Li, Rui Xue, Zhongyuan Xia, and Shaoqing Lei.The Roles of Autophagy in Acute Lung Injury Induced by Myocardial Ischemia Reperfusion in Diabetic Rats.Journal of Diabetes Research.2018 Apr 3. 6. Zhan L, Lei S, Li W, Zhang Y, Wang H, Shi Y, Tian Y.Suppression of microRNA-142-5p attenuates hypoxia-induced apoptosis through targeting SIRT7.Biomed Pharmacother. 2017 Oct;94:394-401. 7. LiYing Zhan, Li Du, Zhongyuan Xia, WenLan Li, Bo Zhao. Study of the expression of GABAA receptor in rats during acute lung injury caused by endotoxin.Genet Mol Res. 2015; 14(4):13312- 13319. 8. LiYing Zhan, XIA ZY, XIA F, Cheng BC. Effect of Radix Paeoniae Rubra on expression of p38MAPK/iNOS/HO-1 in rats with lipopolysaccharide–induced acute lung injury.Chinese Journal of Traumatology.2007;10(5):269-274. 9. LiYing Zhan, Xia ZY, Chen C, Wang XY.Effect of Radix Paeoniae Rubra on the expression of HO-1 and iNOS in rats with eddotoxin-induced acute lung injury, Chinese Journal of Traumatology, 2006,9(3):181-187. |
| Name | Liying Zhan |
| Date of birth | August，1971 |
| Department | Critical Care Medicine Department,Renmin Hospital,Wuhan University. |
| Title | Director, Professor, doctoral tutor |
| zhanliying@whu.edu.cn | |
| TEL | 027-88041911-81075 |
| Research Direction | |
| Sepsis lung injury、ARDS | |
| Personal Profile | |
| With 28 years of clinical experience, I have been responsible for critical care treatment of various complex and critically ill patients. I excel in providing life-saving treatment for critical patients, including severe infections, sepsis/septic shock, acute respiratory distress syndrome (ARDS), post-cardiac arrest bundle therapy, and intensive care during organ transplant surgeries. My current primary research focus lies in the pathogenesis and clinical prevention and treatment of sepsis and ARDS. I have pioneered practical new services and technologies in my department, emphasizing ideological education for young doctors, doctoral and master's students, and resident trainees. I have excelled in educational achievements, leading five projects including the National Natural Science Foundation and Hubei Provincial Natural Science Foundation. I have authored one major publication and published over 30 SCI papers as first author or corresponding author. I received the second prize for scientific and technological progress in Hubei Province. I am currently supervising five master's students and three doctoral students I am mentoring. | |
| Selected Publications | |
|
1.Song WQ, Wang W, Yang YC, Sun Q, Chen H, Zhang
L, Bu XS, Zhan LY, Xia ZY. Parasternal Intercostal Block Complementation
Contributes to Postoperative Pain Relief in Modified Radical Mastectomy
Employing Pectoral Nerve Block I and Serratus-Intercostal Block: A Randomized
Trial. J Pain Res. 2020 Apr 30;13:865-871. 2.Cui SS, Feng XB, Zhang BH, Xia ZY, Zhan LY. Exendin-4 attenuates pain-induced cognitive impairment by alleviating hippocampal neuroinflammation in a rat model of spinal nerve ligation. Neural Regen Res. 2020 Jul;15(7):1333-1339. 3.Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L. Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation. Yonsei Med J. 2019 Dec;60(12):1195-1202. 4. Zhan LY, Lei SQ, Zhang BH, Li WL, Wang HX, Zhao B, Cui SS, Ding H, Huang QM. Overexpression of miR-381 relieves neuropathic pain development via targeting HMGB1 and CXCR4. Biomed Pharmacother. 2018 Nov;107:818-823. 5. Liying Zhan, Yuan Zhang, Wating Su, Qiongxia Zhang, Rong Chen, Bo Zhao, Wei Li, Rui Xue, Zhongyuan Xia, and Shaoqing Lei.The Roles of Autophagy in Acute Lung Injury Induced by Myocardial Ischemia Reperfusion in Diabetic Rats.Journal of Diabetes Research.2018 Apr 3. 6. Zhan L, Lei S, Li W, Zhang Y, Wang H, Shi Y, Tian Y.Suppression of microRNA-142-5p attenuates hypoxia-induced apoptosis through targeting SIRT7.Biomed Pharmacother. 2017 Oct;94:394-401. 7. LiYing Zhan, Li Du, Zhongyuan Xia, WenLan Li, Bo Zhao. Study of the expression of GABAA receptor in rats during acute lung injury caused by endotoxin.Genet Mol Res. 2015; 14(4):13312- 13319. 8. LiYing Zhan, XIA ZY, XIA F, Cheng BC. Effect of Radix Paeoniae Rubra on expression of p38MAPK/iNOS/HO-1 in rats with lipopolysaccharide–induced acute lung injury.Chinese Journal of Traumatology.2007;10(5):269-274. 9. LiYing Zhan, Xia ZY, Chen C, Wang XY.Effect of Radix Paeoniae Rubra on the expression of HO-1 and iNOS in rats with eddotoxin-induced acute lung injury, Chinese Journal of Traumatology, 2006,9(3):181-187. |
武汉大学人民医院
湖北省人民医院