张洪
药学
主任药师，硕士生导师
主任药师，硕士生导师
导师介绍
| 姓名 | 张洪 |
| 出生年月 | 1962年5月 |
| 单位 | 武汉大学人民医院药学部 |
| 所属学科 | 药学 |
| 职务、职称及头衔 | 主任药师，硕士生导师 |
| zhzx8888@163.com | |
| 联系方式 | 13971622566 |
| 研究方向 |
1.药物作用机理及个体化给药研究：药物作用机理及基因多态性研究 2.药物作用信号通路研究：药物作用靶点研究 |
| 个人简介 | 主要从事药物作用机理的科研与教学工作，先后承担国家科技部科技基础性工作专项研究1项，主持省、市级科研项目6项。主编专著1部，副主编专著1部，参编专著2部。目前在研课题4项。近5年在《中国药学杂志》、《中国医院药学杂志》、《中国药师》等杂志上以第一作者或通讯作者发表学术论文70余篇；其中SCI论文10篇，已培养硕士生20余名，目前正在培养的硕士生4名。 |
| 学术任职与荣誉 |
湖北省药学会理事 湖北省中西医结合学会药学专业委员会副主任委员 湖北省药学会医院药学专业委员会副主任委员 中国药学会武汉分会常务理事 武汉市药学会医院药学专业委员会副主任委员 《中国医院药学杂志》常务编委 《医药导报》杂志常务编委 |
| 教育履历 |
1980.09-1984.06湖北中医药大学药学本科生 获学士学位 1996.09-1998.07武汉大学医学部 获硕士学位 |
| 工作履历 |
1984.07－1990.10武汉中联制药厂助理工程师、工程师 1990.10－1992.07武汉大学人民医院药学部药师 1992.08－1997.09武汉大学人民医院药学部主管药师 1997.10－2001.08武汉大学人民医院药学部副主任药师 2001－至今武汉大学人民医院主任药师 |
| 成果获奖 | 1.《甲基供体（S-腺苷蛋氨酸及甜菜碱）治疗慢性肝病的基础及临床探讨》2014年获湖北省科技进步三等奖 |
| 代表性论著 |
1.Jie-Fang Gao , Hong Zhang , Jian Lv, et al. Effects of the
long and short isoforms of TIPE3 on the growth and metastasis of gastric
cancer[J]. Biomedicine &
Pharmacotherapy，2020,124:1-9. 2.Jie-Fang Gao, Hong Zhang, Jian Lv, et al.Associations of the IL-17A rs2275913 and IL-17F rs763780 polymorphisms with the risk of digestive system neoplasms: A meta-analysis[J]. Lnternational Immunopharmacology，2019，67：248-259 3. Lv Jian，Zhang Hong，Wang Li，et al. Effects of A94T and P84L Polymorphisms Within the TNF-alpha Gene on Proliferation and Activation of Hepatic Stellate Cells，2019，38（2）：162-169 4. Lv J , Bai R , Wang L , et al. Artesunate may inhibit liver fibrosis via the FAK/Akt/β-catenin pathway in LX-2 cells[J]. BMC Pharmacology and Toxicology，2018，19(10)：1-7 5. S Feng, J Liu, B Cheng, A Deng, H Zhang. (-)-Epigallocatechin-3-gallate protects PC12 cells against corticosterone-induced neurotoxicity via the hedgehog signaling pathway[J]. Experimental & Therapeutic Medicine，2018 , 15 (5)：4284-4290 6. Wei D, Zhang H, Peng R, et al. ABCB2(1249G>A) polymorphism implicates altered transport activity for sorafenib[J]. Xenobiotica，2017，47(11)：1008-1014. 7. Cuiyuan Huang, Hong Zhang, Ruidan Bai, Li Wang, and Jian Lv. A896G and C1196T Polymorphisms Withinthe TLR4 Gene Abate Toll-Like Receptor4-Mediated Signaling in HepG2 Cells[J]. DNA and cell biology，2017，36（11）：1029-1038. 8. Cuiyuan Huang, Hong Zhang, Ruidan Bai. Advances in ultrasound-targeted microbubble-mediated gene therapy for liver fibrosis[J]. Acta Pharmaceutica Sinica B 2017，7(4)：447–452 9. RuiPeng, Hong Zhang, Ying Zhang, Dan-Yun Wei. Impacts of ABCB1 (G1199A) polymorphism onresistance, uptake, and efflux to steroid drugs[J]. Xenobiotica, 2016，46（10）: 948–952. |
| Name | ZHANG HONG |
| Date of birth | May，1962 |
| Department | Department of pharmacy，Renmin Hospital,Wuhan University. |
| Title | Chief pharmacist, Master's tutor |
| zhzx8888@163.com | |
| TEL | 13971622566 |
| Research Direction |
1.
Study on the mechanism of drug action and individualized administration:
Study on Mechanism of drug action and gene polymorphism 2. Study on the signaling pathway of drug action: Study on the target of drug action |
| Personal Profile | He is mainly engaged in scientific research and teaching of drug action mechanism.He has undertaken 1 research project on science and technology basic work of the Ministry of science and technology; 6 items from the provincial and municipal science and Technology Department.1 monographs of the editor in chief, 1 monographs of the deputy editor in chief, 2 monographs of the Participate in writing. 4 items of research at present. Besides, in the last 5 years, by the first author or correspondence author, more than 70 academic papers were published in the Journal of Chinese Pharmacy, the Chinese Journal of Hospital Pharmacy and the Chinese Pharmacist, including 10 SCI papers. By now, more than 20 master students have been educated. At present, there are 4 masters studying with him. |
| Selected Publications |
1.Jie-Fang Gao , Hong Zhang , Jian Lv, et al. Effects of the
long and short isoforms of TIPE3 on the growth and metastasis of gastric
cancer[J]. Biomedicine &
Pharmacotherapy，2020,124:1-9. 2.Jie-Fang Gao, Hong Zhang, Jian Lv, et al.Associations of the IL-17A rs2275913 and IL-17F rs763780 polymorphisms with the risk of digestive system neoplasms: A meta-analysis[J]. Lnternational Immunopharmacology，2019，67：248-259 3. Lv Jian，Zhang Hong，Wang Li，et al. Effects of A94T and P84L Polymorphisms Within the TNF-alpha Gene on Proliferation and Activation of Hepatic Stellate Cells，2019，38（2）：162-169 4. Lv J , Bai R , Wang L , et al. Artesunate may inhibit liver fibrosis via the FAK/Akt/β-catenin pathway in LX-2 cells[J]. BMC Pharmacology and Toxicology，2018，19(10)：1-7 5. S Feng, J Liu, B Cheng, A Deng, H Zhang. (-)-Epigallocatechin-3-gallate protects PC12 cells against corticosterone-induced neurotoxicity via the hedgehog signaling pathway[J]. Experimental & Therapeutic Medicine，2018 , 15 (5)：4284-4290 6. Wei D, Zhang H, Peng R, et al. ABCB2(1249G>A) polymorphism implicates altered transport activity for sorafenib[J]. Xenobiotica，2017，47(11)：1008-1014. 7. Cuiyuan Huang, Hong Zhang, Ruidan Bai, Li Wang, and Jian Lv. A896G and C1196T Polymorphisms Withinthe TLR4 Gene Abate Toll-Like Receptor4-Mediated Signaling in HepG2 Cells[J]. DNA and cell biology，2017，36（11）：1029-1038. 8. Cuiyuan Huang, Hong Zhang, Ruidan Bai. Advances in ultrasound-targeted microbubble-mediated gene therapy for liver fibrosis[J]. Acta Pharmaceutica Sinica B 2017，7(4)：447–452 9. RuiPeng, Hong Zhang, Ying Zhang, Dan-Yun Wei. Impacts of ABCB1 (G1199A) polymorphism onresistance, uptake, and efflux to steroid drugs[J]. Xenobiotica, 2016，46（10）: 948–952. |
武汉大学人民医院
湖北省人民医院