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  • 夏中元 麻醉学
    科主任,基地主任,二级教授,一级主任医师,博士生导师,湖北省医学领军人才,湖北省突出贡献专家,湖北省政府专项津贴,湖北省医德楷模,湖北省五一劳动奖章获得者
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    导师介绍

    姓名 夏中元
    出生年月 1966年2月
    单位 武汉大学人民医院心血管内科
    所属学科 临床医学-外科学
    职务、职称及头衔 科主任,基地主任,二级教授,一级主任医师,博士生导师,湖北省医学领军人才,湖北省突出贡献专家,湖北省政府专项津贴,湖北省医德楷模,湖北省五一劳动奖章获得者
    E-mail xiazhongyuan2005@aliyun.com
    联系方式 027-88041911转81028
    研究方向 1.糖尿病心肌缺血再灌注损伤的防治
    2.围术期重要脏器保护
    个人简介 在临床麻醉及危重医学方面有较深造诣,部分技术在华中地区具有开创性和很高的省内外知名度并获得国内外同行专家的认可。主持国家自然科学基金面上项目六项;出版及参编专著十部、专利十项;获湖北省科技进步二等奖两项、科技成果推广二等奖一项;发表SCI论文百余篇。 
    学术任职与荣誉 教育部高等学校临床医学类专业教学指导委员会麻醉学专业教学指导分委员会副主任委员
    中国医药教育协会麻醉专业委员会副主任委员
    中国医师协会麻醉学分会常务委员
    中国心胸血管麻醉学会常务委员
    中国研究型医院学会麻醉学专业委员会常务委员
    湖北省医学会麻醉学分会第八届主任委员
    武汉市医学会麻醉学分会第十届主任委员
    教育履历 1983.09-1988.06湖北医学院临床医疗系本科生获学士学位
    1991.09-1994.06湖北医科大学麻醉学硕士研究生获硕士学位
    2002.09-2005.06武汉大学外科学博士研究生获博士学位
    工作履历 1988.07-1991.08   湖北医科大学附属第二医院住院医师
    1994.07-1996.10   湖北医科大学附属第一医院住院医师
    1996.11-1999.10   湖北医科大学附属第一医院主治医师
    1999.11-2004.10   武汉大学人民医院副主任医师/副教授
    2004.11-2011.11   武汉大学人民医院主任医师(四级岗)
    2005.02-2006.02   加拿大University of British Columbia大学访问学者
    2007.11-2017.11   武汉大学人民医院教授(四级岗)
    2017.11-2019.11     武汉大学人民医院教授(三级岗)
    2011.12-2013.11   武汉大学人民医院二级主任医师(三级岗)
    2013.12-至今     武汉大学人民医院一级主任医师(二级岗)
    2019.12-至今     武汉大学人民医院教授(二级岗)
    成果获奖 1. <缺血再灌注对多脏器损伤影响的机制与防治探讨>获2014年湖北省科技进步二等奖
    2. <术期糖尿病肾脏再灌注损伤易损性增加的机制与防治探>获2017年湖北省科技进步二等奖
    3.  <高危病人和重危手术围术期重要脏器保护的临床应用>获2020年湖北省科技推广二等奖
    代表性论著 1.Lei S, Jiang F, Su W, Chen C, Chen J, Mei W, Zhan LY, Jia Y, Zhang L, Liu D, Xia ZY, Xia Z. Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection. EClinicalMedicine. 2020; 100331
    2.  Qiu Z, Ming H, Lei S, Zhou B, Zhao B, Yu Y, Xue R, Xia Z. Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury. Cell Death Dis. 2021; 12(1): 43.
    3.  Qiao Q, Fu X, Huang R, Lei S, Leng Y, Liu Z, Xia Z, Jiang X. Ropivacaine-loaded, hydroxypropyl chitin thermo-sensitive hydrogel combined with hyaluronan: an injectable, sustained-release system for providing long-lasting local anesthesia in rats. Reg Anesth Pain Med. 2022; 47(4): 234-241
    4.Zhou B, Lei S, Xue R, Leng Y, Xia Z, Xia ZY. DJ-1 overexpression restores ischaemic post- conditioning-mediated cardioprotection in diabetic rats: role of autophagy. Clin Sci (Lond). 2017; 131(11):1161-1178.
    5.  Meng QT, Cao C, Wu Y, Liu HM, Li W, Sun Q, Chen R, Xiao YG, Tang LH, Jiang Y, Leng Y, Lei SQ, Lee CC, Barry DM, Chen X, Xia ZY. Ischemic post-conditioning attenuates acute lung injury induced by intestinal ischemia-reperfusion in mice: role of Nrf2. Lab Invest. 2016; 96(10): 1087-1104.
    6.  Xue R, Lei S, Xia ZY, Wu Y, Meng Q, Zhan L, Su W, Liu H, Xu J, Liu Z, Zhou B, Xia Z. Selective Inhibition of PTEN Preserves Ischemic Postconditioning Cardioprotection in STZ- induced Type1 Diabetic Rats: Role of the PI3K/Akt and JAK2/STAT3 Pathways. Clin Sci (Lond). 2016; 130(5): 377-392.
    7.   Xu J, Li H, Irwin MG, Xia ZY, Mao X, Lei S, Wong GT, Hung V, Cheung CW, Fang X, Clanachan AS, Xia Z. Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats. Crit Care Med. 2014; 42(8): e583-594.

    Name Xia Zhongyuan  
    Date of birth Feb,1966 
    Department Department of Anesthesiology,Renmin Hospital, Wuhan University.
    Title Director, Professor, doctoral tutor
    Email xiazhongyuan2005@aliyun.com
    TEL 027-88041911-81028
    Research Direction 1. Prevention and treatment of myocardial ischemia-reperfusion injury in diabetes
    2. Perioperative protection of vital organs
    Personal Profile Dr. Zhongyuan Xia is currently a professor and director of department of anethesiology at Renmin Hospital of Wuhan University. He leads the department to commit to providing clinical excellence in perioperative care as well as training of future anesthesiologists and scientists. His academic and research fields include basic and clinical research of peroperative protection of important organ especially pharmacological(anesthetic) preconditioning and postconditioning in diabetic cardiomyophathy. Dr. Xia has received over several scientific awards in his research field, of which 3 were the second grade award of progresses of science and technology of Hubei province. Besides, he owned 6 national patents. Dr.Xia is the deputy editor of the Practical clinical Anesthesia Procedures, Anesthesia Management of Patient with Myocadial Ischemia and Cerebral Ischemia and Anesthesiology of General practitioners, the editorial board Member of Elderly Anesthesia and Practical clinical Therapeutics. He also participated in translation of Miller Anesthesiology. Dr. Xia has published over 300 articles, of which 40 were in peer-reviewed scientific journals such as Diabetes, Crit Care Med, Anesth Analg, PLoS One, Injury, Oxidative Medicine and cellular Longevity. He is a regular invited reviewer for a whole range of journals and grant bodies(NSFC).  He is currently serving as principal investigator for several multi-center clinical trials. Dr.Xia is a Fellow of the Chinese Society of Anesthesiology, the Chinese Medical Doctor Association. He is also the standing committee of Chinese Society of Cariothracic and Vascular Anesthesiology, the director committee of Hubei Medical Association of anesthesiology.
    Selected Publications 1.Lei S, Jiang F, Su W, Chen C, Chen J, Mei W, Zhan LY, Jia Y, Zhang L, Liu D, Xia ZY, Xia Z. Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection. EClinicalMedicine. 2020; 100331
    2.  Qiu Z, Ming H, Lei S, Zhou B, Zhao B, Yu Y, Xue R, Xia Z. Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury. Cell Death Dis. 2021; 12(1): 43.
    3.  Qiao Q, Fu X, Huang R, Lei S, Leng Y, Liu Z, Xia Z, Jiang X. Ropivacaine-loaded, hydroxypropyl chitin thermo-sensitive hydrogel combined with hyaluronan: an injectable, sustained-release system for providing long-lasting local anesthesia in rats. Reg Anesth Pain Med. 2022; 47(4): 234-241
    4.Zhou B, Lei S, Xue R, Leng Y, Xia Z, Xia ZY. DJ-1 overexpression restores ischaemic post- conditioning-mediated cardioprotection in diabetic rats: role of autophagy. Clin Sci (Lond). 2017; 131(11):1161-1178.
    5.  Meng QT, Cao C, Wu Y, Liu HM, Li W, Sun Q, Chen R, Xiao YG, Tang LH, Jiang Y, Leng Y, Lei SQ, Lee CC, Barry DM, Chen X, Xia ZY. Ischemic post-conditioning attenuates acute lung injury induced by intestinal ischemia-reperfusion in mice: role of Nrf2. Lab Invest. 2016; 96(10): 1087-1104.
    6.  Xue R, Lei S, Xia ZY, Wu Y, Meng Q, Zhan L, Su W, Liu H, Xu J, Liu Z, Zhou B, Xia Z. Selective Inhibition of PTEN Preserves Ischemic Postconditioning Cardioprotection in STZ- induced Type1 Diabetic Rats: Role of the PI3K/Akt and JAK2/STAT3 Pathways. Clin Sci (Lond). 2016; 130(5): 377-392.
    7.   Xu J, Li H, Irwin MG, Xia ZY, Mao X, Lei S, Wong GT, Hung V, Cheung CW, Fang X, Clanachan AS, Xia Z. Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats. Crit Care Med. 2014; 42(8): e583-594.