吕菁君
急诊医学科
主任医师，急诊医学&全科医学硕士生导师，急诊医学住院医师规培基地主任
主任医师，急诊医学&全科医学硕士生导师，急诊医学住院医师规培基地主任
导师介绍
| 姓名 | 吕菁君 |
| 出生年月 | 1973年11月 |
| 单位 | 武汉大学人民医院急诊科 |
| 所属学科 | 临床医学-急诊医学 |
| 职务、职称及头衔 |
主任医师，急诊医学&全科医学硕士生导师，急诊医学住院医师规培基地主任 |
| lvjingjun@whu.edu.cn | |
| 联系方式 | 13886162487 |
| 研究方向 |
复苏与内科急危重症的防治与机制研究 |
| 个人简介 | 主要研究方向：复苏以及内科急危重症的防治与机制研究。主持国家自然科学基金项目和国家重点研发计划共3项。2017年获得湖北省科学技术奖二等奖选择性激动肾上腺素能受体在心肺复苏及复苏后脏器保护中的应用与机制探讨（第2名）。2018年获得中国医师协会急诊医师分会 E-Training最佳课程建设奖。2018年第十九次湖北省急诊学术年会优秀讲者评选第一名。参与编写国家卫生健康委员会住院医师规范化培训规划教材-急诊医学（第二版）人民卫生出版社；急危重症容量管理[M],人民卫生出版社（2018）；急诊科常见病用药[M],人民卫生出版社（2016）；急诊无创机械通气ABC[M],北京大学医学出版社（2013）；《骨髓间充质干细胞临床研究进展》 人民卫生出版社。《中华急诊医学杂志》第五届编辑委员会通讯编委。已培养急诊医学和全科医学硕士研究生10名，均就业三甲甲等医院急诊科或者重症医学科。目前在读研究生4名。 |
| 学术任职与荣誉 |
武汉市医师协会急诊医学分会副主任委员、湖北省医学会急诊医学分会副主任委员、 中国医师协会急诊医师分会全国青年委员以及科研与创新学组委员、 中华医学会急诊医学分会危重病学组委员 |
| 教育履历 |
2005/09-2008/06，武汉大学人民医院，心内科博士毕业 2001/09-2004/06，武汉大学人民医院，心内科硕士毕业 1991/09-1996/07，原湖北医学院咸宁医学院，临床医学，本科毕业 |
| 工作履历 |
1.
2019/04-2020.09，Duke
University Medical Center, Durham, North Carolina, USA高级访问学者 2. 2017/09-至今，武汉大学人民医院，急诊医学住院医师规培基地主任 3. 2014/11-至今，武汉大学人民医院，急诊科，主任医师，硕士研究生导师 4. 2012/11-至今，武汉大学人民医院，急诊科，全科医学，硕士研究生导师 5. 2011/09-至今，武汉大学人民医院，急诊科，副教授，急诊医学硕士研究生导师 6. 2009/02-2011/02，University Arkansas of Medical Science, Little Rock, Arkansas, USA心血管内科博士后 7. 2009/01-2014/11，武汉大学人民医院，急诊科，副主任医师 8. 2004/08-2008/12，武汉大学人民医院，急诊科，主治医师/讲师 |
| 成果获奖 |
2018年中国医师协会急诊医师分会E-Training最佳课程建设奖 2018年第十九次湖北省急诊学术年会优秀讲者评选第一名 2017年湖北省科学技术奖二等奖选择性激动肾上腺素能受体在心肺复苏及复苏后脏器保护中的应用与机制探讨(2016J-232-073-052-R02) |
| 代表性论著 |
1.叶璐，吕菁君*，魏捷，孙红双，蒋舒玉，张东梅.C57BL/6小鼠心肺复苏后心肌细胞线粒体自噬及细胞凋亡的相互作用与调节机制的研究[J].临床急诊杂志, 2016,17(1):16-21. 2.孙红双，吕菁君*，魏捷，叶璐，蒋舒玉，孙胜男.窒息法与高钾合并窒息法制备心肺复苏后全身炎症反应小鼠模型的比较研究[J].临床急诊杂志, 2016, 17 (1): 9-15. 3.孙胜男,吕菁君*,魏捷.氧化型钙/钙调素依赖性蛋白激酶Ⅱ——一个新型心脏氧化应激标志物[J].中华急诊医学杂志, 2015, 24(3):335-338. 4.蒋舒玉,吕菁君*,魏捷,等.新型布尼亚病毒感染致发热伴血小板减少综合征预后相关性分析[J].中华急诊医学杂志,2015,24(4):380-385. 5.张东梅,吕菁君*,魏捷,等.138例不同首发症状的多发性骨髓瘤临床回顾性分析[J].中华急诊医学杂志,2017,26(10):1172-1179. 6.姜洁,吕菁君*,魏捷.细胞焦亡途径以及细胞焦亡对脓毒症免疫反应的潜在影响[J].中华急诊医学杂志, 2019,28(5): 655-658. 7.姜洁，吕菁君*，叶璐.可溶性血栓调节蛋白及中性粒细胞明胶酶相关脂质运载蛋白早期预测脓毒症相关急性肾损伤的临床研究[J].中华急诊医学杂志,2020.29(4):535-543. |
| Name | Jingjun Lyu |
| Date of birth | Nov，1973 |
| Department | Emergency Department，Renmin Hospital,Wuhan University. |
| Title | Professor |
| lvjingjun@whu.edu.cn | |
| TEL | 13886162487 |
| Research Direction | resuscitation and the prevention , treatment, and mechanism research of emergency and critical illness. |
| Personal Profile |
I
have extensive experience in clinical work, teaching, and scientific
research. I preside over 3 projects including the National Natural Science
Foundation of China and the National Key R&D Program. In 2017, I won the
second prize of Hubei Science and Technology Award: the application and
mechanism of selective stimulating adrenergic receptors in cardiopulmonary
resuscitation and multiple organ protection after resuscitation. In 2018, I
won the E-Training Best Course Construction Award of the Emergency Physician
Branch in the Chinese Medicine Association, an outstanding speaker at the
19th Hubei Provincial Emergency Academic Annual Conference in 2018. I
published 4 manuscripts by the People's Sanitary Publishing Press. I have trained 10 postgraduates of emergency medicine or general practice medicine, all of whom are employed in the emergency department or critical care medicine department of top-tier hospitals. Currently there are 4 graduate students in my team. |
| Selected Publications |
1.
Jingjun Lu (吕菁君), Xianwei
Wang, Wenze Wang, Harish Muniyappa, Changping Hu, Sona Mitra, Bobbie Long,
Kumuda Das, Jawahar L Mehta*. LOX-1 Abrogation Reduces Cardiac Hypertrophy
and Collagen Accumulation Following Chronic Ischemia in the Mouse. Gene
Therapy, 2012, 19(5): 522-531. 2. Jingjun Lu* (吕菁君), Xianwei Wang, Wenze Wang, Harish Muniyappa, Abhishek Deshmukh, Changping Hu, Kumuda Das, Jawahar L Mehta*. Abrogation of lectin-like oxidized LDL receptor-1 attenuates acute myocardial ischemia-induced renal dysfunction by modulating systemic and local inflammation. Kidney International，2012, 82(4): 436-444. 3. Xianwei Wang#, Jingjun Lu# (吕菁君,共同第一作者), Magomed Khaidakov, Sona Mitra , Zufeng Ding , Tanu Goyal, Jawahar L. Mehta*. Delineation of the effects of angiotensin type 1 and 2 receptors on HL-1 cardiomyocyte apoptosis. APOPTOSIS, 2012, 17(8): 908-915. 4. Jingjun Lu（吕菁君）, Sona Mitra, Xianwei Wang, Magomed Khaidakov, Jawahar L. Mehta*. Oxidative Stress and Lectin-Like Ox-LDL-Receptor LOX-1 in Atherogenesis and Tumorigenesis. Antioxidants & Redox Signaling, 2011, 15(8): 2301-2333. 5. Sona Mitra#, Magomed Khaidakov#, Jingjun Lu # (吕菁君,共同第一作者), Srinivas Ayyadevara, Jackob Szwedo, Xian Wei Wang, Chien Chen, Said Khaidakov, Srikanth Reddy Kasula, Annjanette Stone, Igor Pogribny, Jawahar L. Mehta*. Prior Exposure to Oxidized Low Density Lipoprotein Limits Apoptosis in Subsequent Generations of Endothelial Cells by Altering Promoter Methylation. American Journal of Physiology-Heart and Circulatory physiology, 2011, 301(2): H506-H513. 6. Jingjun Lü*（吕菁君）, Jawahar L. Mehta. LOX-1: A Critical Player in the Genesis and Progression of Myocardial Ischemia. Cardiovascular Drugs and Therapy, 2011,25(5):431-440. 7. Lü Jingjun*（吕菁君）, Zhang Yan, Wei Jie, Zhao Dongdong, Lin Guosheng, Bao Mingwei. Effects and mechanism of esmolol given during cardiopulmonary resuscitation in a procine ventricular fibrillation model. RESUSCITATION, 2009, 80 (9): 1052-1059. 8. JingJun Lyu# *（吕菁君）, Jawahar L Mehta, Yi Li, Ye L, Sun SN, Sun HS, Li JC, Zhang DM, Wei J. Mitochondrial autophagy and NLRP3 Inflammasome in pulmonary tissues from severe combined immunodeficient mice after cardiac arrest and cardiopulmonary resuscitation[J]. Chin Med J 2018; 131(10): 1174-84. 9. Jingjun Lyu# *（吕菁君）, Xiaobing Long , Tuxiu Xie , Guijun Jiang , Jie Jiang , Lu Ye , Qiongzi Li. Copper oxide nanoparticles promote α-synuclein oligomerization and underlying neurotoxicity as a model of Parkinson's disease. Journal of Molecular Liquids 2021,323: 115051. 10. Feifei Yan, Fengming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Jingjun Lv# (吕菁君,共同第一作者), Shaogeng Zhang, Lu Ye, Ming Gong, Zhibo Liu, Jie Wei, Tuxiu Xie, Kai-Feng Xu, George F. Gao , Fu-Sheng Wang , Lin Cai , Chengyu Jiang. Antihypertensive drugs are associated with reduced fatal outcomes and improved clinical characteristics in elderly COVID-19 patients. Cell Discovery, 2020(6):77. https://doi.org/10.1038/s41421-020-00221-6 |
武汉大学人民医院
湖北省人民医院