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  • 邱波 骨外
    骨Ⅱ科副主任,二级主任医师,副教授,硕士生导师
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    导师介绍

    姓名 邱波
    出生年月 1971年9月
    单位 武汉大学人民医院骨Ⅱ科
    所属学科 临床医学-内科学
    职务、职称及头衔 骨Ⅱ科副主任,二级主任医师,副教授,硕士生导师
    E-mail drqb123@163.com
    联系方式 027-88041911转81093或13517207115
    研究方向 1.骨关节病的基础与临床研究;2.代谢性骨关节炎
    个人简介 主要从事骨外科疾病的诊治与科研工作,主持完成国家自然科学基金面上项目1项、省科技厅、省卫计委课题12项。以第一作者和通讯作者发表论文80余篇,其中SCI论文20篇。已培养硕士生18名。目前正在培养的硕士生3名。
    学术任职与荣誉 中华医学会数字医学会分会第二届委员会青年委员会委员,湖北省医学会数字医学分会第一届副主任委员,湖北省医学会骨科分会第六、七届委员会委员,湖北省中西医结合学会骨伤专业委员会第六、七、八届委员会委员,武汉中西医结合学会第一、二届颈肩腰腿疼专业委员会委员,武汉市医学会第七届骨科学分会常务委员,湖北省生物医学工程学会关节委员会委员,湖北省/武汉市医疗事故鉴定委员会鉴定专家,Biomedicines期刊客座编辑,《中华实验外科》杂志审稿专家。
    教育履历 1990.9-1995.6同济医科大学临床医学专业本科生获学士学位1996.9-1999.6湖北医科大学外科学硕士研究生获硕士学位2002.9-2005.6武汉大学第一临床学院外科学博士研究生获博士学位
    工作履历 1999.7-2002.9黄石市第二医院骨科主治医师2005.7-2007.10武汉大学人民医院骨科主治医师2007.11~2012.11武汉大学人民医院骨科副主任医师,副教授2012.12-至今武汉大学人民医院骨科主任医师
    成果获奖 《羧甲基壳聚糖对骨关节炎软骨退变的实验研究》2010年获湖北省自然科学叁等奖
    代表性论著 1.Wang C, Zhang X, Qiu B.Genetically predicted circulating serum homocysteine levels on osteoporosis: a two-sample mendelian randomization study.  Sci Rep. 2023 ;13(1):9063.
    2.Liang C, Xing H, Wang C, Xu X, Hao Y, Qiu B.Resveratrol Improves the Progression of Osteoarthritis by Regulating the SIRT1-FoxO1 Pathway-Mediated Cholesterol Metabolism. Mediators Inflamm.2023 ;2023:293623
    3.Gong Z, Wang Y, Li L, Li X, Qiu B, Hu Y. Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway. Food Chem Toxicol. 2023;174:113644.
    4.Xing H, Liang C, Wang C, Xu X, Hu Y, Qiu B. Metformin mitigates cholesterol accumulation via the AMPK/SIRT1 pathway to protect osteoarthritis chondrocytes. Biochem Biophys Res Commun. 2022 ;632:113-121.
    5.Liang C, Xing H, Wang C, Xu X, Hao Y, Qiu B. Resveratrol protection against IL-1β-induced chondrocyte damage via the SIRT1/FOXO1 signaling pathway. J Orthop Surg Res. 2022;17(1):406.
    6. Peng Yi, Xiongfeng Xu, Jiawei Yao and Bo Qiu. Analysis of mRNA expression and DNA methylation datasets according to the genomic distribution of CpG sites for osteoarthritis. Front Genet. 2021;12:618803.
    7. Peng Yi, Xiongfeng Xu, Jiawei Yao, Bo Qiu. Effect of DNA methylation on gene transcription is associated with the distribution of methylation sites across the genome in osteoarthritis. Exp Ther Med. 2021;22(1):719.
    8. Yi P, Xu X, Qiu B, Li H. Impact of chitosan membrane culture on the expression of pro- and anti-inflammatory cytokines in mesenchymal stem cells. Exp Ther Med. 2020;20(4): 3695-3702.
    9. Xu X, Qiu B, Yi P, Li H. Overexpression of miR-206 in osteosarcoma and its associated molecular mechanisms as assessed through TCGA and GEO databases, Oncol Lett. 2020;19(3):1751-1758.
    10. Qiu B, Xu XF, Deng RH, Xia GQ, Shang XF, Zhou PH.Hyaluronic acid-chitosan nanoparticles encoding CrmA attenuate interleukin-1β induced inflammation in synoviocytes in vitro. Int J Mol Med.  2019;43(2):1076-1084.
    11. Qiu B, Xu XF, Deng RH, Xia GQ, Shang XF, Zhou PH.Construction of chitosan/ZnO nanocomposite filmby in situ precipitation. Int J Biol Macromol. 2019;122:82-87.
    12.Zhou PH, Qiu B, Deng RH, Li HJ, Xu XF, Shang XF. Chondroprotective Effects of Hyaluronic Acid-Chitosan Nanoparticles Containing Plasmid DNA Encoding Cytokine Response Modifier A in a Rat Knee Osteoarthritis Model. Cell Physiol Biochem. 2018;47(3):1207-1216.
    Name Bo Qiu
    Date of birth Sept, 1971
    Department Orthopedics Department, Renmin Hospital, Wuhan University.
    Title deputy director,Grade II Chief physician, associate professor, master's tutor
    Email drqb123@163.com
    TEL 027-88041911-81093 or 13517207115
    Research Direction 1.The basic and clinical study of osteoarthritis;2.Metabolic Osteoarthritis
    Personal Profile He is mainly engaged in the diagnosis and treatment of  Orthopedic diseases, and has been awarded 1 items for the National Natural Science Foundation,12 items from the Provincial science and Technology Department and the Provincial Health Department. There are more than 80 articles published by the first author and corresponding author, including 20 SCI papers. By now, he has educated 18 masters. At present, there are 3 Masters studying with him.
    Selected Publications 1.Wang C, Zhang X, Qiu B.Genetically predicted circulating serum homocysteine levels on osteoporosis: a two-sample mendelian randomization study.  Sci Rep. 2023 ;13(1):9063.
    2.Liang C, Xing H, Wang C, Xu X, Hao Y, Qiu B.Resveratrol Improves the Progression of Osteoarthritis by Regulating the SIRT1-FoxO1 Pathway-Mediated Cholesterol Metabolism. Mediators Inflamm.2023 ;2023:293623
    3.Gong Z, Wang Y, Li L, Li X, Qiu B, Hu Y. Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway. Food Chem Toxicol. 2023;174:113644.
    4.Xing H, Liang C, Wang C, Xu X, Hu Y, Qiu B. Metformin mitigates cholesterol accumulation via the AMPK/SIRT1 pathway to protect osteoarthritis chondrocytes. Biochem Biophys Res Commun. 2022 ;632:113-121.
    5.Liang C, Xing H, Wang C, Xu X, Hao Y, Qiu B. Resveratrol protection against IL-1β-induced chondrocyte damage via the SIRT1/FOXO1 signaling pathway. J Orthop Surg Res. 2022;17(1):406.
    6. Peng Yi, Xiongfeng Xu, Jiawei Yao and Bo Qiu. Analysis of mRNA expression and DNA methylation datasets according to the genomic distribution of CpG sites for osteoarthritis. Front Genet. 2021;12:618803.
    7. Peng Yi, Xiongfeng Xu, Jiawei Yao, Bo Qiu. Effect of DNA methylation on gene transcription is associated with the distribution of methylation sites across the genome in osteoarthritis. Exp Ther Med. 2021;22(1):719.
    8. Yi P, Xu X, Qiu B, Li H. Impact of chitosan membrane culture on the expression of pro- and anti-inflammatory cytokines in mesenchymal stem cells. Exp Ther Med. 2020;20(4): 3695-3702.
    9. Xu X, Qiu B, Yi P, Li H. Overexpression of miR-206 in osteosarcoma and its associated molecular mechanisms as assessed through TCGA and GEO databases, Oncol Lett. 2020;19(3):1751-1758.
    10. Qiu B, Xu XF, Deng RH, Xia GQ, Shang XF, Zhou PH.Hyaluronic acid-chitosan nanoparticles encoding CrmA attenuate interleukin-1β induced inflammation in synoviocytes in vitro. Int J Mol Med.  2019;43(2):1076-1084.
    11. Qiu B, Xu XF, Deng RH, Xia GQ, Shang XF, Zhou PH.Construction of chitosan/ZnO nanocomposite filmby in situ precipitation. Int J Biol Macromol. 2019;122:82-87.
    12.Zhou PH, Qiu B, Deng RH, Li HJ, Xu XF, Shang XF. Chondroprotective Effects of Hyaluronic Acid-Chitosan Nanoparticles Containing Plasmid DNA Encoding Cytokine Response Modifier A in a Rat Knee Osteoarthritis Model. Cell Physiol Biochem. 2018;47(3):1207-1216.