胡克
呼吸
Ⅱ科主任，教授，一级主任医师，博士生导师
Ⅱ科主任，教授，一级主任医师，博士生导师
导师介绍
| 姓名 | 胡克 |
| 出生年月 | 1965年11月 |
| 单位 | 武汉大学人民医院呼吸与危重症医学Ⅱ科 |
| 所属学科 | 临床医学-内科学 |
| 职务、职称及头衔 | Ⅱ科主任，教授，一级主任医师，博士生导师 |
| hukejx@163.com | |
| 联系方式 | 027-88041919-82215 |
| 研究方向 |
1.睡眠呼吸障碍性疾病 2.肺部感染性疾病 |
| 个人简介 | 主要从事呼吸系统疾病的诊治与科研工作，获国家自然科学基金面上项目4项。以第一作者或通讯作者发表论文100余篇。已培养硕士生及博士生30余人。 |
| 学术任职与荣誉 | 中国睡眠研究会常务理事 |
| 教育履历 |
1980.09-1985.06，江西医学院医疗系本科生，学士学位 1991.09-1994.06，湖北医科大学第一临床学院内科学硕士研究生，硕士学位 2001.09-2004.06，武汉大学第一临床学院内科学博士研究生，博士学位 |
| 工作履历 |
1985.09-1991.08，江西新余市人民医院，内科医师 1991.07-至今，武汉大学人民医院呼吸与危重症医学科 |
|
|
|
| 代表性论著 |
1. Xiong M, Zhao Y, Mo H, Yang H, Yue F, Hu K. Intermittent
hypoxia increases ROS/HIF-1α 'related oxidative stress and inflammation and
worsens bleomycin-induced pulmonary fibrosis in adult male C57BL/6J mice. Int
Immunopharmacol. 2021 Nov;100:108165. doi: 10.1016/j.intimp.2021.108165. 2. Zha S, Yang H, Yue F, Zhang Q, Hu K. The influence of acute morphine use on obstructive sleep apnea: A systematic review and meta-analysis. J Sleep Res. 2022 Jun;31(3):e13523. doi: 10.1111/jsr.13523. 3. Wang M, Zhao Y, Hu W, Zhao D, Zhang Y, Wang T, Zheng Z, Li X, Zeng S, Liu Z, Lu L, Wan Z, Hu K. Treatment of Coronavirus Disease 2019 Patients With Prolonged Postsymptomatic Viral Shedding With Leflunomide: A Single-center Randomized Controlled Clinical Trial. Clin Infect Dis. 2021 Dec 6;73(11):e4012-e4019. doi: 10.1093/cid/ciaa1417. 4. Mo H, Wang M, Wang M, Han Y, Zhang Y, Hu K. Detectable antibodies against SARS-CoV-2 in newborns from mothers infected with COVID-19 at different gestational ages. Pediatr Neonatol. 2021 May;62(3):321-323. doi: 10.1016/j.pedneo.2021.03.011. 5. Zhao D, Zeng Z, Mo H, Hu W, Tian S, Hu D, Gong L, Hu K. Orexin-A inhibits cerebral ischaemic inflammatory injury mediated by the nuclear factor-κB signalling pathway and alleviates stroke-induced immunodepression in mice. Brain Res Bull. 2021 Sep;174:296-304. doi: 10.1016/j.brainresbull.2021.06.021. |
| Name | Ke Hu |
| Date of birth | November,1965 |
| Department | Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University. |
| Title | Director, Professor, doctoral tutor |
| hukejx@163.com | |
| TEL | 027-88041911-82215 |
| Research Direction |
1.
Sleep-disodered breathing; 2. Pulnonary infectious diseases. |
| Personal Profile | He is mainly engaged in the diagnosis and treatment of respiratory system diseases,and has been awarded 4 items for the National Natural Science Foundation. There are more than 100 articles published by the first author or corresponding author. By now, he has educated >30 masters and doctors. |
| Selected Publications |
1.
Hu K, Wang M, Zhao Y, Zhang Y, Wang T, Zheng Z, Li X, Zeng S, Zhao D, Li H,
Xu K, Lan K. A Small-Scale Medication of Leflunomide as a Treatment of
COVID-19 in an Open-Label Blank-Controlled Clinical Trial. Virol Sin. 2020
Jul 21:1-9. doi: 10.1007/s12250-020-00258-7. 2. Hu K, Guan WJ, Bi Y, Zhang W, Li L, Zhang B, Liu Q, Song Y, Li X, Duan Z, Zheng Q, Yang Z, Liang J, Han M, Ruan L, Wu C, Zhang Y, Jia ZH, Zhong NS.Efficacy and safety of Lianhuaqingwen capsules, a repurposed Chinese herb, in patients with coronavirus disease 2019: A multicenter, prospective, randomized controlled trial. Phytomedicine. 2020 May 16:153242. doi: 10.1016/j.phymed.2020.153242. 3. Zheng Z, Dong M, Hu K. A preliminary evaluation on the efficacy of ozone therapy in the treatment of COVID-19. J Med Virol. 2020 May 21:10.1002/jmv.26040. doi: 10.1002/jmv.26040. 4. Hu Z, Song X, Hu K, Ruan Y, Zeng F. Association between sleep duration and asthma in different weight statuses (CHNS 2009-2015). Sleep Breath. 2020 Apr 25. doi: 10.1007/s11325-020-02081-6. 5. Xiong M, Hu W, Dong M, Wang M, Chen J, Xiong H, Zhong M, Jiang Y, Liu D, Hu K.The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2019 Nov 13;14:2497-2505. doi: 10.2147/COPD.S223354. 6. Zhu J, Zhao Z, Nie Q, Wang Y, Fu Z, Guo X, Hu K. Effect of lung function on the apnea-hypopnea index in patients with overlap syndrome: a multicenter cross-sectional study.Sleep Breath. 2019 Nov 25. doi: 10.1007/s11325-019-01961-w. 7. Zhu J, Kang J, Li X, Wang M, Shang M, Luo Y, Xiong M, Hu K.Chronic intermittent hypoxia vs chronic continuous hypoxia: Effects on vascular endothelial function and myocardial contractility.Clin Hemorheol Microcirc. 2020;74(4):417-427. doi: 10.3233/CH-190706.PMID: 31683472 8. Hu ZG, Hu K, Li WX, Zeng FJ.Prognostic factors and nomogram for cancer-specific death in non small cell lung cancer with malignant pericardial effusion. PLoS One. 2019 May 16;14(5):e0217007. 9. Tang S, Zhou X, Hu K, Liu P, Xiong M, Li H.BThe role of gonadal hormones in the hypoglossal discharge activity of rats exposed to chronic intermittent hypoxia.rain Res Bull. 2019 Jul;149:175-183. doi: 10.1016/j.brainresbull.2019.04.017. 10. Liu P, Zhang HM, Hu K, Zhou XF, Tang S.Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.J Cell Physiol. 2019 Aug;234(8):13534-13543. |
武汉大学人民医院
湖北省人民医院