姚宝珍
儿科学
儿科主任，基地主任，主任医师，硕士生导师
儿科主任，基地主任，主任医师，硕士生导师
导师介绍
| 姓名 | 姚宝珍 |
| 出生年月 | 1962年12月 |
| 单位 | 武汉大学人民医院儿科 |
| 所属学科 | 临床医学-儿科学 |
| 职务、职称及头衔 | 科主任，基地主任，主任医师，硕士生导师 |
| professoryao@aliyun.com | |
| 联系方式 | 027-88041911转81543或13986147892 |
| 研究方向 |
1.儿童神经系统疾病的基础与临床 2.儿童罕见病 |
| 个人简介 | 从事儿科临床、教学、科研工作30余年， 临床工作：在完成儿科常见多发病的临床诊治以外，开展儿童神经系统疾病、疑难罕见病的诊治：如儿童癫痫、各种脑炎、智力发育障碍、孤独症谱系障碍、注意缺陷多动障碍、抽动障碍等疾病的诊治。指导本科生和研究生的基础和临床研究工作，荣获武汉大学本科优秀教学业绩奖，“优秀指导老师”称号。参与国家级、省科技厅、卫健委、市级课题10余项，参入国家多中心临床研究5项，参编专著3部，发表论文100余篇，其中SCI 20篇，已培养硕士研究生45名，目前正在培养的硕士生10名。 |
| 学术任职与荣誉 | 湖北省儿科学会副主任委员、罕见病学组组长、中国医师协会第四届儿科分会委员、儿童神经学组委员，中华医学会儿科分会感染控制委员会委员、中华医学会儿科学分会罕见病学组委员、世界中联优生优育专委会常委、中国抗癫痫协会委员、湖北省抗癫痫协会常务理事、湖北省合理用药管理专家委员会委员，教育部科技成果奖、华夏医学科技奖、博士基金评审专家 |
| 教育履历 |
1981.09-1986.06武汉大学第一临床学院临床儿科专业本科生获学士学位 1995.09-1998.06武汉大学第一临床学院儿科学硕士研究生获硕士学位 2004.09-2007.06武汉大学第一临床学院内科学博士研究生获博士学位 |
| 工作履历 |
1986.07-1993.10 武汉大学人民医院儿科住院医师 1993.11-1998.07 武汉大学人民医院儿科主治医师 1998.08-2004.06 武汉大学人民医院儿科副主任医师 2004.07-至今 武汉大学人民医院儿科主任医师 |
| 成果获奖 | 1.《癫痫发病相关机制及癫痫儿童生活质量的评估》2016年获湖北省科技进步三等奖 |
| 代表性论著 |
[1]Peng Xia,Yao Bao-Zhen,Wang Shun et al. 2020.The Protective
Effect of Breastfeeding on Febrile Seizures: A Case-Control Study .Breastfeed
Med, 15: 709-714. [2]Wang S., Xie L., Xu Y., Yu S., Yao B., Xiang D.2020. Sleep disturbances among medical workers during the outbreak of COVID-2019. Occup Med (Lond), 70(5), 364-369. [3]Niu, P., Yao, B., Wei, L., Zhu, H., Fang, C., Zhao, Y. 2019. Construction of prognostic risk prediction model based on high-throughput sequencing expression profile data in childhood acute myeloid leukemia. Blood cells, molecules & diseases. 77, 43-50. [4]Wang, S., Mao, S., Yao, B., Xiang, D., Fang, C. 2019. Effects of low-frequency repetitive transcranial magnetic stimulation on depression- and anxiety-like behaviors in epileptic rats. Journal of integrative neuroscience. 18, 237-243. [5]Wang, S., Xiang, D., Fang, C., Yao, B., 2019. Association between breastfeeding and Kawasaki disease: a case-control study. European journal of pediatrics. 10.1007/s00431-019-03529-y. [6]Niu, P., Yao, BZ,., Zhao, YQ. Yu,SQ 2018 Notch 1 Signaling Enhances the Differentiation of Mesenchymal Stem Cells to Cardiomyogenic Cells、Nanosci Nanotechnol Lett、10(10):1380-1386 [7]Li, X., Huang, W., He, B., Zhou, L., Huang, X., Yao, B., 2017. Role of blocking ADAM10 hydrolysis site on N-cadherin by single-chain antibody in ventricular remodeling. Experimental and therapeutic medicine. 14, 4215-4223. [8]Zhang, H., Caudle, Y., Wheeler, C., Zhou, Y., Stuart, C., Yao, B., Yin, D., 2018. TGF-β1/Smad2/3/Foxp3 signaling is required for chronic stress-induced immune suppression. Journal of neuroimmunology. 314, 30-41. [9]Zhang, H., Li, H., Shaikh, A., Caudle, Y., Yao, B., Yin, D., 2018. Inhibition of MicroRNA-23b Attenuates Immunosuppression During Late Sepsis Through NIK, TRAF1, and XIAP. The Journal of infectious diseases. 218, 300-311. [10]Zhang, H., Caudle, Y., Shaikh, A., Yao, B., Yin, D., 2018. Inhibition of microRNA-23b prevents polymicrobial sepsis-induced cardiac dysfunction by modulating TGIF1 and PTEN. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 103, 869-878. [11]袁启锋,姚宝珍.谷氨酸-谷氨酰胺循环异常与孤独症谱系障碍研究进展[J].生物技术进展,2021,11(02):170-175. [12]付细舟,姚宝珍.纳洛酮联合阿昔洛韦治疗儿童病毒性脑炎的临床分析[J/OL].武汉大学学报(医学版):1-5[2021-07-09].https://doi.org/10.14188/j.1671-8852.2020.0721. [13]张宏达,姚宝珍.儿童癫痫停药后复发的危险因素分析[J].医学综述,2021,27(03):614-617+624. [14]王华倩,姚宝珍,叶静萍,王军陵,刘芳.高龄产妇的晚期早产儿早期体格和神经发育分析[J].武汉大学学报(医学版),2021,42(03):452-456. [15]张宏达,姚宝珍.维生素D与癫痫的相关性[J].医学综述,2020,26(17):3343-3347. [16]徐宇明,宋诩,张爱明,芦伟,袁启锋,彭霞,姚宝珍.20例儿童新型冠状病毒肺炎的临床特点[J/OL].武汉大学学报(医学版):1-6[2021-07-09].https://doi.org/10.14188/j.1671-8852.2020.0502. [17]彭霞,姚宝珍,方聪聪,徐宇明,王华倩.7例儿童抗N-甲基-D-天冬氨酸受体脑炎的临床研究[J].武汉大学学报(医学版),2020,41(04):665-670. [18]庹虎,刘芳,王军陵,叶静萍,夏利平,牛萍,张海菊,邓巍,姚宝珍,方成志.儿童新型冠状病毒感染的临床特征及家庭防控[J].武汉大学学报(医学版),2020,41(03):357-361. [19]彭霞,方聪聪,徐宇明,姚宝珍.铁死亡与自噬在疾病中的研究进展[J].疑难病杂志,2019,18(12):1284-1287+1292. [20]芳菲,牛迪,姚宝珍,等.异种脱细胞真皮基质联合丝素蛋白辅料对幼儿Ⅱ度烫伤的临床疗效研究[J].中华细胞与干细胞杂志（电子版）, 2019, 9(5):298-303. |
| Name | BAOZHEN YAO |
| Date of birth | December，1962 |
| Department | Pediatric Department，Renmin Hospital,Wuhan University. |
| Title | Director, Professor, Master tutor |
| professoryao@aliyun.com | |
| TEL | 027-88041911-81543 or 13986147892 |
| Research Direction |
1.The
basis and clinical disease of children's nervous system 2. Rare disease in children |
| Personal Profile | She is mainly engaged in the pediatric clinical, teaching and scientific research for more than 30 years. In clinical work: not only in common and frequently occurring diseases of pediatric clinical diagnosis and treatment, also actively develop children's nervous system disease, difficult diagnosis and treatment of rare diseases, such as child epilepsy, variety of encephalitis, developmental disorders, autism spectrum disorders, attention deficit hyperactivity disorder, and tic disorders diagnosis and treatment of disease. Actively involved in basic and clinical research teaching undergraduate and graduate students, to guide the scientific research work of graduate students,won the Wuhan University undergraduate outstanding teaching performance award, "excellent instructor" title. Actively involved in scientific research, participated in National level, provincial Department of Science and Technology, Health Commission and municipal level topic, a total of more than 10 items, participated in 5 national multi-center clinical research projects, and participated in 3 books. Besides, there are more than 100 papers published, including nearly 20 SCI papers. By now, she has educated 45 masters. At present, there are 10 masters studying with her. |
| Selected Publications |
[1]Peng Xia,Yao Bao-Zhen,Wang Shun et al. 2020.The Protective
Effect of Breastfeeding on Febrile Seizures: A Case-Control Study .Breastfeed
Med, 15: 709-714. [2]Wang S., Xie L., Xu Y., Yu S., Yao B., Xiang D.2020. Sleep disturbances among medical workers during the outbreak of COVID-2019. Occup Med (Lond), 70(5), 364-369. [3]Niu, P., Yao, B., Wei, L., Zhu, H., Fang, C., Zhao, Y. 2019. Construction of prognostic risk prediction model based on high-throughput sequencing expression profile data in childhood acute myeloid leukemia. Blood cells, molecules & diseases. 77, 43-50. [4]Wang, S., Mao, S., Yao, B., Xiang, D., Fang, C. 2019. Effects of low-frequency repetitive transcranial magnetic stimulation on depression- and anxiety-like behaviors in epileptic rats. Journal of integrative neuroscience. 18, 237-243. [5]Wang, S., Xiang, D., Fang, C., Yao, B., 2019. Association between breastfeeding and Kawasaki disease: a case-control study. European journal of pediatrics. 10.1007/s00431-019-03529-y. [6]Niu, P., Yao, BZ,., Zhao, YQ. Yu,SQ 2018 Notch 1 Signaling Enhances the Differentiation of Mesenchymal Stem Cells to Cardiomyogenic Cells、Nanosci Nanotechnol Lett、10(10):1380-1386 [7]Li, X., Huang, W., He, B., Zhou, L., Huang, X., Yao, B., 2017. Role of blocking ADAM10 hydrolysis site on N-cadherin by single-chain antibody in ventricular remodeling. Experimental and therapeutic medicine. 14, 4215-4223. [8]Zhang, H., Caudle, Y., Wheeler, C., Zhou, Y., Stuart, C., Yao, B., Yin, D., 2018. TGF-β1/Smad2/3/Foxp3 signaling is required for chronic stress-induced immune suppression. Journal of neuroimmunology. 314, 30-41. [9]Zhang, H., Li, H., Shaikh, A., Caudle, Y., Yao, B., Yin, D., 2018. Inhibition of MicroRNA-23b Attenuates Immunosuppression During Late Sepsis Through NIK, TRAF1, and XIAP. The Journal of infectious diseases. 218, 300-311. [10]Zhang, H., Caudle, Y., Shaikh, A., Yao, B., Yin, D., 2018. Inhibition of microRNA-23b prevents polymicrobial sepsis-induced cardiac dysfunction by modulating TGIF1 and PTEN. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 103, 869-878. [11]袁启锋,姚宝珍.谷氨酸-谷氨酰胺循环异常与孤独症谱系障碍研究进展[J].生物技术进展,2021,11(02):170-175. [12]付细舟,姚宝珍.纳洛酮联合阿昔洛韦治疗儿童病毒性脑炎的临床分析[J/OL].武汉大学学报(医学版):1-5[2021-07-09].https://doi.org/10.14188/j.1671-8852.2020.0721. [13]张宏达,姚宝珍.儿童癫痫停药后复发的危险因素分析[J].医学综述,2021,27(03):614-617+624. [14]王华倩,姚宝珍,叶静萍,王军陵,刘芳.高龄产妇的晚期早产儿早期体格和神经发育分析[J].武汉大学学报(医学版),2021,42(03):452-456. [15]张宏达,姚宝珍.维生素D与癫痫的相关性[J].医学综述,2020,26(17):3343-3347. [16]徐宇明,宋诩,张爱明,芦伟,袁启锋,彭霞,姚宝珍.20例儿童新型冠状病毒肺炎的临床特点[J/OL].武汉大学学报(医学版):1-6[2021-07-09].https://doi.org/10.14188/j.1671-8852.2020.0502. [17]彭霞,姚宝珍,方聪聪,徐宇明,王华倩.7例儿童抗N-甲基-D-天冬氨酸受体脑炎的临床研究[J].武汉大学学报(医学版),2020,41(04):665-670. [18]庹虎,刘芳,王军陵,叶静萍,夏利平,牛萍,张海菊,邓巍,姚宝珍,方成志.儿童新型冠状病毒感染的临床特征及家庭防控[J].武汉大学学报(医学版),2020,41(03):357-361. [19]彭霞,方聪聪,徐宇明,姚宝珍.铁死亡与自噬在疾病中的研究进展[J].疑难病杂志,2019,18(12):1284-1287+1292. [20]芳菲,牛迪,姚宝珍,等.异种脱细胞真皮基质联合丝素蛋白辅料对幼儿Ⅱ度烫伤的临床疗效研究[J].中华细胞与干细胞杂志（电子版）, 2019, 9(5):298-303. |
武汉大学人民医院
湖北省人民医院