耿庆
心胸外
科主任，教授，一级主任医师，博士生导师
科主任，教授，一级主任医师，博士生导师
导师介绍
| 姓名 | 耿庆 |
| 出生年月 | 1972年5月 |
| 单位 | 武汉大学人民医院胸外科 |
| 所属学科 | 临床医学-外科学 |
| 职务、职称及头衔 | 科主任，教授，一级主任医师，博士生导师 |
| gengqingwhu@whu.edu.cn | |
| 联系方式 | 027-88041911转82240或18071093208 |
| 研究方向 |
1.肺损伤及肺保护 2.胸部肿瘤基础与临床研究 |
| 个人简介 | 主要从事胸外科疾病的诊治与科研工作，主持国家自然科学基金面上项目2项，主持湖北省自然科学基金创新群体项目及中华国际医学交流基金等省/市级项目8项。以第一或通讯作者在NEJM、Thorax、EBioMedicine、CLIN TRANSL MED、《中华外科杂志》、《中华实验外科杂志》等杂志上发表论文80余篇，其中SCI论文近30篇，影响因子超过150。已培养硕士生8名。目前正在培养的博士生13名，硕士生6名。 |
| 学术任职与荣誉 |
中华医学会胸心血管外科学分会食管疾病学组委员 中华医学会胸心血管外科学分会青委会秘书长 中国老年学和老年医学学会食管癌康复专业委员会副主任委员 中国抗癌协会食管癌专业委员会青委 吴阶平医学基金会交感神经外科专业委员会常委 吴阶平医学基金会模拟医学部胸外科专业委员会常委 国家医学考试中心全国医师资格考试试题开发专家委员会委员 湖北省临床肿瘤学会胸外科专委会主任委员 湖北省医师协会胸外科分会副主委 湖北省医学会创伤外科分会副主任委员 湖北省临床肿瘤学会肺癌专委会常委 湖北省医学会胸心血管外科分会常委 湖北省抗癌协会肺癌专业委员会委员 湖北省抗癌协会食管癌专业委员会委员 |
| 教育履历 |
1989.09-1994.06武汉大学第一临床学院临床医学专业本科生获学士学位 1994.09-1996.06武汉大学第一临床学院外科学硕士研究生获硕士学位 1996.09-1999.06武汉大学第一临床学院外科学博士研究生获博士学位 |
| 工作履历 |
1999.07-2002.10 北京大学深圳医院胸外科主治医师 2002.10-2005.11 北京大学深圳医院胸外科副主任医师 2005.11-2009.10 北京大学深圳医院胸外科主任医师 2008.03-2008.09 美国华盛顿大学访问学者 2008.09-2009.09 美国LOYOLA大学医学中心博士后 2009.10-至今 武汉大学人民医院胸外科主任医师 |
| 成果获奖 |
1.《肺移植缺血再灌注损伤机制及临床关键技术创新》2020年获湖北省科技进步一等奖（第一完成人） |
| 代表性论著 |
1．Ning L, Wei W, Wenyang J, Rui X,
Qing G*. Cytosolic DNA-STING-NLRP3 axis is involved in murine acute lung
injury induced by lipopolysaccharide. Clin Transl Med 2020, 10(7):
e228. 2．Zhang L, Fan T, Yang S, Feng H, Hao B, Lu Z, Xiong R, Shen X, Jiang W, Wang W and Geng Q*. Comparison of clinical characteristics of COVID-19 between elderly patients and young patients: a study based on a 28-day follow-up[J]. Aging (Albany NY),2020,12(20):19898-19910. 3．Jiang WY, Ren J, Zhang XH, Lu ZL, Feng HJ, Yao XL, Li DH, Xiong R, Fan T and Geng Q*. CircC3P1 attenuated pro-inflammatory cytokine production and cell apoptosis in acute lung injury induced by sepsis through modulating miR-21[J]. J Cell Mol Med,2020,24(19):11221-11229. 4. Zhang L, Meng H and Geng Q*. Commentary: Peripheral Circulating Exosome-Mediated Delivery of miR-155 as a Novel Mechanism for Acute Lung Inflammation[J]. Front Med (Lausanne),2020,7:507. 5. Fan T, Hao B, Yang S, Shen B, Huang Z, Lu Z, Xiong R, Shen X, Jiang W, Zhang L, Li D, He R, Meng H, Lin W, Feng H, Geng Q*. Nomogram for Predicting COVID-19 Disease Progression Based on Single-Center Data: Observational Study and Model Development. JMIR Med Inform 2020, 8(9): e19588. 6. Li D, He R, Hou G, Ming W, Fan T, Chen L, Zhang L, Jiang W, Wang W, Lu Z, Feng H, Geng Q*. Characterization of the Esophageal Microbiota and Prediction of the Metabolic Pathways Involved in Esophageal Cancer. Front Cell Infect Microbiol 2020, 10: 268. 7. Fan T, Yang S, Huang Z, Wang W, Guo X, Pan S, Zhang B, Xu Y, Fang Y, Mao Z, Hu H, Geng Q*. Autophagy decreases alveolar epithelial cell injury by regulating the release of inflammatory mediators. J CELL PHYSIOL 2020, 235(11): 7982-7995. 8. Zhang L, Mai W, Hao B, Jiang W, Geng Q*. Promising response to a PD-1 inhibitor (sintilimab) in non-small cell lung cancer: A case report[J]. Medicine (Baltimore),2020,99(21):e19790. 9. Lu Z, Feng H, Shen X, He R, Meng H, Lin W, Geng Q*. MiR-122-5p protects against acute lung injury via regulation of DUSP4/ERK signaling in pulmonary microvascular endothelial cells[J]. Life Sci,2020,256:117851. 10. Meng H, Xiong R, He R, Lin W, Hao B, Zhang L, Lu Z, Shen X, Fan T, Jiang W, Yang W, Li T, Chen J, Geng Q*. CT imaging and clinical course of asymptomatic cases with COVID-19 pneumonia at admission in Wuhan, China. J Infect 2020, 81(1): e33-e39. 11. He R, Lu Z, Zhang L, Fan T, Xiong R, Shen X, Feng H, Meng H, Lin W, Jiang W, Geng Q*. The clinical course and its correlated immune status in COVID-19 pneumonia. J Clin Virol. 2020 Apr 12;127:104361. 12. Hao B, Zhang L, Fan T, Liu B, Jiang W, Hu H, Geng Q*. Survival Following Segmentectomy or Lobectomy in Patients With Stage IB Non-small-cell Lung Cancer[J]. Front Oncol,2020,10:661. 13. Zhang L, Song Y, Chen L, Li D, Feng H, Lu Z, Fan T, Chen Z, Livingston MJ, Geng Q*. MiR-20a-containing exosomes from umbilical cord mesenchymal stem cells alleviates liver ischemia/reperfusion injury. J Cell Physiol. 2020 Apr;235(4):3698-3710. 14. Zhou Q#, Geng Q#, Wang L#, Huang J#, Liao M, Li Y, Ding Z, Yang S, Zhao H, Shen Q, Pan C, Lou J, Lu S, Chen C, Luo Q. Value of folate receptor-positive circulating tumour cells in the clinical management of indeterminate lung nodules: A non-invasive biomarker for predicting malignancy and tumour invasiveness. EBioMedicine. 2019 Mar;41:236-243. 15. Fan T, Wang W, Guo X, Geng Q*. 'Malignant' pleural effusion with abdominal gossypiboma. Thorax. 2018 Oct;73(10):992-993. 16. Fan T, Yang S, Geng Q*. Smoking and Other Risk Factors in Type 2 Diabetes. N Engl J Med. 2018 Dec 27;379(26):2573. 17. Fan T, Huang Z, Wang W, Zhang B, Xu Y, Mao Z, Chen L, Hu H, Geng Q*. Proteasome inhibition promotes autophagy and protects from endoplasmic reticulum stress in rat alveolar macrophages exposed to hypoxia-reoxygenation injury. J Cell Physiol. 2018 Oct;233(10):6748-6758. 18. Fan T, Chen L, Huang Z, Wang W, Zhang B, Xu Y, Mao Z, Hu H, Geng Q*. Autophagy Activation by Rapamycin Before Hypoxia-Reoxygenation Reduces Endoplasmic Reticulum Stress in Alveolar Epithelial Cells. Cell Physiol Biochem. 2017;41(1):79-90. 19. Fan T, Huang Z, Chen L, Wang W, Zhang B, Xu Y, Pan S, Mao Z, Hu H, Geng Q*. Associations between autophagy, the ubiquitin-proteasome system and endoplasmic reticulum stress in hypoxia-deoxygenation or ischemia-reperfusion. Eur J Pharmacol. 2016 Nov 15;791:157-167. 20. Geng Q*, Fan T, Zhang B, Wang W, Xu Y, Hu H. Five microRNAs in plasma as novel biomarkers for screening of early-stage non-small cell lung cancer. Respir Res. 2014 Nov 25;15(1):149. |
| Name | QING GENG |
| Date of birth | May，1972 |
| Department | Thoracic Surgery，Renmin Hospital,Wuhan University. |
| Title | Director, Professor, doctoral tutor |
| gengqingwhu@whu.edu.cn | |
| TEL | 027-88041911-82240 or 18071093208 |
| Research Direction |
1.
Lung injury and lung protection 2. Basic and clinical research on thoracic cancer |
| Personal Profile | He is mainly engaged in the diagnosis and treatment of chest diseases,and has been awarded 2 items for the National Natural Science Foundation, 8 items from the Natural Science Foundation of Hubei Province, China International Medical Foundation,et al.. Besides,there are more than 80 articles published in the journal NEJM, Thorax, EBioMedicine, CLIN TRANSL MED, Chinese Journal of Surgery, and Chinese Journal of Experimental Surgery by the first author or corresponding author, including nearly 30 SCI papers with more than 150 influencing factors. By now, he has educated 8 masters. At present, there are 13 doctors and 6 Masters studying with him. |
| Selected Publications |
1．Ning L, Wei W, Wenyang J, Rui X,
Qing G*. Cytosolic DNA-STING-NLRP3 axis is involved in murine acute lung
injury induced by lipopolysaccharide. Clin Transl Med 2020, 10(7):
e228. 2．Zhang L, Fan T, Yang S, Feng H, Hao B, Lu Z, Xiong R, Shen X, Jiang W, Wang W and Geng Q*. Comparison of clinical characteristics of COVID-19 between elderly patients and young patients: a study based on a 28-day follow-up[J]. Aging (Albany NY),2020,12(20):19898-19910. 3．Jiang WY, Ren J, Zhang XH, Lu ZL, Feng HJ, Yao XL, Li DH, Xiong R, Fan T and Geng Q*. CircC3P1 attenuated pro-inflammatory cytokine production and cell apoptosis in acute lung injury induced by sepsis through modulating miR-21[J]. J Cell Mol Med,2020,24(19):11221-11229. 4. Zhang L, Meng H and Geng Q*. Commentary: Peripheral Circulating Exosome-Mediated Delivery of miR-155 as a Novel Mechanism for Acute Lung Inflammation[J]. Front Med (Lausanne),2020,7:507. 5. Fan T, Hao B, Yang S, Shen B, Huang Z, Lu Z, Xiong R, Shen X, Jiang W, Zhang L, Li D, He R, Meng H, Lin W, Feng H, Geng Q*. Nomogram for Predicting COVID-19 Disease Progression Based on Single-Center Data: Observational Study and Model Development. JMIR Med Inform 2020, 8(9): e19588. 6. Li D, He R, Hou G, Ming W, Fan T, Chen L, Zhang L, Jiang W, Wang W, Lu Z, Feng H, Geng Q*. Characterization of the Esophageal Microbiota and Prediction of the Metabolic Pathways Involved in Esophageal Cancer. Front Cell Infect Microbiol 2020, 10: 268. 7. Fan T, Yang S, Huang Z, Wang W, Guo X, Pan S, Zhang B, Xu Y, Fang Y, Mao Z, Hu H, Geng Q*. Autophagy decreases alveolar epithelial cell injury by regulating the release of inflammatory mediators. J CELL PHYSIOL 2020, 235(11): 7982-7995. 8. Zhang L, Mai W, Hao B, Jiang W, Geng Q*. Promising response to a PD-1 inhibitor (sintilimab) in non-small cell lung cancer: A case report[J]. Medicine (Baltimore),2020,99(21):e19790. 9. Lu Z, Feng H, Shen X, He R, Meng H, Lin W, Geng Q*. MiR-122-5p protects against acute lung injury via regulation of DUSP4/ERK signaling in pulmonary microvascular endothelial cells[J]. Life Sci,2020,256:117851. 10. Meng H, Xiong R, He R, Lin W, Hao B, Zhang L, Lu Z, Shen X, Fan T, Jiang W, Yang W, Li T, Chen J, Geng Q*. CT imaging and clinical course of asymptomatic cases with COVID-19 pneumonia at admission in Wuhan, China. J Infect 2020, 81(1): e33-e39. 11. He R, Lu Z, Zhang L, Fan T, Xiong R, Shen X, Feng H, Meng H, Lin W, Jiang W, Geng Q*. The clinical course and its correlated immune status in COVID-19 pneumonia. J Clin Virol. 2020 Apr 12;127:104361. 12. Hao B, Zhang L, Fan T, Liu B, Jiang W, Hu H, Geng Q*. Survival Following Segmentectomy or Lobectomy in Patients With Stage IB Non-small-cell Lung Cancer[J]. Front Oncol,2020,10:661. 13. Zhang L, Song Y, Chen L, Li D, Feng H, Lu Z, Fan T, Chen Z, Livingston MJ, Geng Q*. MiR-20a-containing exosomes from umbilical cord mesenchymal stem cells alleviates liver ischemia/reperfusion injury. J Cell Physiol. 2020 Apr;235(4):3698-3710. 14. Zhou Q#, Geng Q#, Wang L#, Huang J#, Liao M, Li Y, Ding Z, Yang S, Zhao H, Shen Q, Pan C, Lou J, Lu S, Chen C, Luo Q. Value of folate receptor-positive circulating tumour cells in the clinical management of indeterminate lung nodules: A non-invasive biomarker for predicting malignancy and tumour invasiveness. EBioMedicine. 2019 Mar;41:236-243. 15. Fan T, Wang W, Guo X, Geng Q*. 'Malignant' pleural effusion with abdominal gossypiboma. Thorax. 2018 Oct;73(10):992-993. 16. Fan T, Yang S, Geng Q*. Smoking and Other Risk Factors in Type 2 Diabetes. N Engl J Med. 2018 Dec 27;379(26):2573. 17. Fan T, Huang Z, Wang W, Zhang B, Xu Y, Mao Z, Chen L, Hu H, Geng Q*. Proteasome inhibition promotes autophagy and protects from endoplasmic reticulum stress in rat alveolar macrophages exposed to hypoxia-reoxygenation injury. J Cell Physiol. 2018 Oct;233(10):6748-6758. 18. Fan T, Chen L, Huang Z, Wang W, Zhang B, Xu Y, Mao Z, Hu H, Geng Q*. Autophagy Activation by Rapamycin Before Hypoxia-Reoxygenation Reduces Endoplasmic Reticulum Stress in Alveolar Epithelial Cells. Cell Physiol Biochem. 2017;41(1):79-90. 19. Fan T, Huang Z, Chen L, Wang W, Zhang B, Xu Y, Pan S, Mao Z, Hu H, Geng Q*. Associations between autophagy, the ubiquitin-proteasome system and endoplasmic reticulum stress in hypoxia-deoxygenation or ischemia-reperfusion. Eur J Pharmacol. 2016 Nov 15;791:157-167. 20. Geng Q*, Fan T, Zhang B, Wang W, Xu Y, Hu H. Five microRNAs in plasma as novel biomarkers for screening of early-stage non-small cell lung cancer. Respir Res. 2014 Nov 25;15(1):149. |
武汉大学人民医院
湖北省人民医院