谭诗云
消化
科主任，主任医师，博士生导师
科主任，主任医师，博士生导师
导师介绍
| 姓名 | 谭诗云 |
| 出生年月 | 1962年10月 |
| 单位 | 武汉大学人民医院消化内科 |
| 所属学科 | 临床医学-内科学 |
| 职务、职称及头衔 | 科主任，主任医师，博士生导师 |
| 812328105@qq.com | |
| 联系方式 | 027-88041911转81237 |
| 研究方向 | 1.脂肪肝防治；2.早起消化系统肿瘤内镜诊疗优化；3.消化系肿瘤防治 |
| 个人简介 | 主要从事消化系疾病的诊治与科研工作，主持或参与国家自然基金、国家卫计委重点项目、湖北省自然基金重点项目、武汉市科技局重点项目、湖北省卫计委基金项目10余项。主编及参编教材《消化系统疾病诊断与治疗学》、《实用消化病学》、《消化科疑难问题解析》等。杂志上发表论文180余篇，其中SCI收录40余篇。已培养博、硕士生50余名，目前正在培养的博士生3名，硕士生8名。 |
| 学术任职与荣誉 |
中华医学会内镜学会超声内镜学组委员 中国医师协会结直肠肿瘤专委会肠外与肠内营养专委会副主任委员 中国抗癌协会内镜专委会委员 中华医学会消化学分会老年病学组委员 湖北省医学会胰腺病分会常委 武汉市消化学会副主任委员 湖北省肝病学会常委 湖北省内镜学会委员 |
| 教育履历 |
1985.06毕业于湖北医学院（现武汉大学医学部）咸宁分院 获学士学位 1992.06毕业于湖北医科大学（现武汉大学医学部） 获硕士学位 2005.10毕业于武汉大学医学院 获博士学位 |
| 工作履历 |
1985.7-1989.8湖北医学学院咸宁分院内科学教研室助教 1992.7-2002.9湖北医科大学消化内科 主治医生副教授 2002.10-至今武汉大学人民医院消化内科教授主任医生 |
| 成果获奖 |
1.消化道肿瘤的化疗耐药、侵袭转移的机制及临床研究2017年湖北省科技进步二等奖 2.联合检测CDw75、MMP-9、TIMP-1等肿瘤基因判断胃癌预后的意义2005年度湖北省科技进步叁等奖 3.实用消化病学2001年度湖北省科技进步叁等奖 4.HPV与消化道肿瘤的关系2000年度湖北省科技进步叁等奖 |
| 代表性论著 |
1.Yitian
Guo, Deqiang Ye, Guifang Yang, Guozhen Liu, Xiaochen Cui, Shiyun Tan, Yi Guo.
Demonstration of a new entity of non-perforated appendicitis through studying
cluster of appendicitis. Sci Rep. 2022 Jul 21;12(1):12464. doi:
10.1038/s41598-022-16682-6. 2.Xingchen Liao, Wei Wang, Baoping Yu, Shiyun Tan. Thrombospondin-2 acts as a bridge between tumor extracellular matrix and immune infiltration in pancreatic and stomach adenocarcinomas: an integrative pan-cancer analysis. Cancer Cell Int. 2022 Jun 14;22(1):213. doi: 10.1186/s12935-022-02622-x. 3.Ming Li, Dongqiang Xu, Yijun Zhan, Shiyun Tan. IPO7 promotes pancreatic cancer progression via regulating ERBB pathway. Clinics (Sao Paulo).2022 May 16;77:100044. doi: 10.1016/j.clinsp.2022.100044. eCollection 2022. 4.Yitian Guo, Deqiang Ye, Guifang Yang, Guozhen Liu, Xiaochen Cui, Shiyun Tan, Yi Guo. Cluster of Acute Appendicitis Among High School Tibetan Students in Nanchang, China: Investigation, Control, and Prevention. Front Public Health. 2022 Apr 15;10:889793. doi: 10.3389/fpubh.2022.889793. eCollection 2022. 5.Ming Li, Ou Cai, Yuanjie Yu, Shiyun Tan. Paeonol inhibits the malignancy of Apatinib-resistant gastric cancer cells via LINC00665/miR-665/MAPK1 axis. Phytomedicine. 2022 Feb;96:153903. doi: 10.1016/j.phymed.2021.153903. Epub 2021 Dec 22. 6.Yuanjie Yu, Tian Tian, Shiyun Tan, Pengbo Wu, Yitian Guo, Ming Li, Mengjun Huang. MicroRNA-665-3p exacerbates nonalcoholic fatty liver disease in mice. Bioengineered. 2022 Feb;13(2):2927-2942. doi: 10.1080/21655979.2021.2017698. 7.Cai O, Huang Z, Li M. Zhang C, Xi F, Tan S. Association between Helicobacter pylori infection and nonalcoholic fatty liver disease: a single center clinical study. Gastroenterol Res Pract 2018, 8040262. doi: 10.1155/2018/8040262. 8.Ye Y, Tan S. Endoscopic ultrasound-guided fine-needle aspiration biopsy for diagnosis of gastric linitis plastica with negative malignant endoscopy biopsies. Oncol Lett. 2018 Oct;16(4):4915-4920. doi: 10.3892/ol.2018.9258. 9.Yu Y, Cai O, Wu P, Tan S. MiR-490-5p inhibits the stemness of hepatocellular carcinoma cells by targeting ECT2. J Cell Biochem. 2019 Jan;120(1):967-976. doi: 10.1002/jcb.27459. 10.Cai O, Huang Z, Li M, Zhang C, Xi F, Tan S. Association between Helicobacter pylori Infection and Nonalcoholic Fatty Liver Disease: A Single-Center Clinical Study. Gastroenterol Res Pract. 2018 Jan 21;2018:8040262. doi:10.1155/2018/8040262. 11.Lu X, Yu Y, Tan S. p53 expression in patients with ulcerative colitis - associated with dysplasia and carcinoma: a systematic meta-analysis. BMC Gastroenterol. 2017 Oct 25;17(1):111. doi: 10.1186/s12876-017-0665-y. 12.Lu XH, Yu YJ, Tan SY, Ding YJ. Primary Small Intestinal Diffuse Large B-cell Lymphoma Masquerading as Crohn's Disease: A Case Report. Chin Med J (Engl). 2017 Sep 5;130(17):2138-2139. doi: 10.4103/0366-6999.213409. 13.Chen JH, Yu Y, Yang Z, Yu WZ, Chen WL, Yu H, Kim MJ, Huang M, Tan S, Luo H, Chen J, Chen JD, Huizinga JD. Intraluminal pressure patterns in the human colon assessed by high-resolution manometry. Sci Rep. 2017 Feb 20;7:41436. doi: 10.1038/srep41436. 14.Cheng D, Lu XH, Li M, Luo HS, Yuan JP, Zhang HD, Tan SY. [Primary diffuse large B-cell lymphoma in the liver: a case report]. Zhonghua Gan Zang Bing Za Zhi. 2016 Sep 20;24(9):699-700. doi: 10.3760/cma.j.issn.1007-3418. 15.Rahman K, Desai C, Iyer SS, Thorn NE, Kumar P, Liu Y, Smith T, Neish AS, Li H, Tan S, Wu P, Liu X, Yu Y, Farris AB, Nusrat A, Parkos CA, Anania FA. Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol. Gastroenterology. 2016 Oct;151(4):733-746.e12. doi: 10.1053/j.gastro.2016.06.022. 16.Wu P, Hua Y, Tan S, Li M, Yongxiang S, Fang G. Interactions of smoking with rs833061 polymorphism on the risk of non-alcoholic fat liver disease in Hubei Han population: a preliminary case-control study. Iran J Basic Med Sci. 2015 Nov;18(11):1112-7. 17. Li H, Chen JH, Yang Z, Huang M, Yu Y, Tan S, Luo H, Huizinga JD. Neurotensin Changes Propulsive Activity into a Segmental Motor Pattern in the Rat Colon. J Neurogastroenterol Motil. 2016 Jul 30;22(3):517-28. doi: 10.5056/jnm15181. 18.Wu P, Shu Y, Li M, Luo H, Zhang G, Tan S. [Study on the interaction between matrix metalloproteinases gene polymorphism and central obesity in nonalcoholic fatty liver disease]. Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Dec;36(12):1415-8. 19.Wu PB, Dai JF, Wang Q, Zhang G, Tan SY, Li M, Ye HL. Association between NCF4 rs4821544T/C polymorphism and inflammatory bowel disease risk in Caucasian: a meta-analysis. Inflamm Res. 2015 Oct;64(10):825-31. doi:10.1007/s00011-015-0866-1. 20.Wu P, Hua Y, Tan S, Li M, Shu Y, Fang G. Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study. Int J Clin Exp Pathol. 2015 Apr 1;8(4):4165-70. |
| Name | SHIYUN TAN |
| Date of birth | October，1962 |
| Department | Gastroenterology Department，Renmin Hospital, Wuhan University. |
| Title | Director, Professor, doctoral tutor |
| 812328105@qq.com | |
| TEL | 027-88041911-81237 |
| Research Direction |
1.
Prevention and treatment of fatty liver disease; 2. Optimization of endoscopic diagnosis and treatment about early gastrointestinal tumors; 3. Prevention and treatment of gastrointestinal tumors |
| Personal Profile | He is mainly engaged in the diagnosis and treatment of digestive diseases, and has participated in more than 10 items from the National Science Foundation, National Health and Planning Commission, Hubei Provincial Science Foundation, Wuhan Municipal Science and Technology Bureau and the Hubei Provincial Health Planning Commission. He has also involved in compiling the planning teaching material Diagnosis and Treatment of Digestive Disease, Practical gastroenterology and Analysis of the difficult problems in Gastrointestinal Department. Besides, there are more than 180 articles published and more than 40 SCI papers. By now, he has educated more than 50 masters and doctors. At present, there are 3 doctors and 8 masters studying with him. |
| Selected Publications |
1.Yitian
Guo, Deqiang Ye, Guifang Yang, Guozhen Liu, Xiaochen Cui, Shiyun Tan, Yi Guo.
Demonstration of a new entity of non-perforated appendicitis through studying
cluster of appendicitis. Sci Rep. 2022 Jul 21;12(1):12464. doi:
10.1038/s41598-022-16682-6. 2.Xingchen Liao, Wei Wang, Baoping Yu, Shiyun Tan. Thrombospondin-2 acts as a bridge between tumor extracellular matrix and immune infiltration in pancreatic and stomach adenocarcinomas: an integrative pan-cancer analysis. Cancer Cell Int. 2022 Jun 14;22(1):213. doi: 10.1186/s12935-022-02622-x. 3.Ming Li, Dongqiang Xu, Yijun Zhan, Shiyun Tan. IPO7 promotes pancreatic cancer progression via regulating ERBB pathway. Clinics (Sao Paulo).2022 May 16;77:100044. doi: 10.1016/j.clinsp.2022.100044. eCollection 2022. 4.Yitian Guo, Deqiang Ye, Guifang Yang, Guozhen Liu, Xiaochen Cui, Shiyun Tan, Yi Guo. Cluster of Acute Appendicitis Among High School Tibetan Students in Nanchang, China: Investigation, Control, and Prevention. Front Public Health. 2022 Apr 15;10:889793. doi: 10.3389/fpubh.2022.889793. eCollection 2022. 5.Ming Li, Ou Cai, Yuanjie Yu, Shiyun Tan. Paeonol inhibits the malignancy of Apatinib-resistant gastric cancer cells via LINC00665/miR-665/MAPK1 axis. Phytomedicine. 2022 Feb;96:153903. doi: 10.1016/j.phymed.2021.153903. Epub 2021 Dec 22. 6.Yuanjie Yu, Tian Tian, Shiyun Tan, Pengbo Wu, Yitian Guo, Ming Li, Mengjun Huang. MicroRNA-665-3p exacerbates nonalcoholic fatty liver disease in mice. Bioengineered. 2022 Feb;13(2):2927-2942. doi: 10.1080/21655979.2021.2017698. 7.Cai O, Huang Z, Li M. Zhang C, Xi F, Tan S. Association between Helicobacter pylori infection and nonalcoholic fatty liver disease: a single center clinical study. Gastroenterol Res Pract 2018, 8040262. doi: 10.1155/2018/8040262. 8.Ye Y, Tan S. Endoscopic ultrasound-guided fine-needle aspiration biopsy for diagnosis of gastric linitis plastica with negative malignant endoscopy biopsies. Oncol Lett. 2018 Oct;16(4):4915-4920. doi: 10.3892/ol.2018.9258. 9.Yu Y, Cai O, Wu P, Tan S. MiR-490-5p inhibits the stemness of hepatocellular carcinoma cells by targeting ECT2. J Cell Biochem. 2019 Jan;120(1):967-976. doi: 10.1002/jcb.27459. 10.Cai O, Huang Z, Li M, Zhang C, Xi F, Tan S. Association between Helicobacter pylori Infection and Nonalcoholic Fatty Liver Disease: A Single-Center Clinical Study. Gastroenterol Res Pract. 2018 Jan 21;2018:8040262. doi:10.1155/2018/8040262. 11.Lu X, Yu Y, Tan S. p53 expression in patients with ulcerative colitis - associated with dysplasia and carcinoma: a systematic meta-analysis. BMC Gastroenterol. 2017 Oct 25;17(1):111. doi: 10.1186/s12876-017-0665-y. 12.Lu XH, Yu YJ, Tan SY, Ding YJ. Primary Small Intestinal Diffuse Large B-cell Lymphoma Masquerading as Crohn's Disease: A Case Report. Chin Med J (Engl). 2017 Sep 5;130(17):2138-2139. doi: 10.4103/0366-6999.213409. 13.Chen JH, Yu Y, Yang Z, Yu WZ, Chen WL, Yu H, Kim MJ, Huang M, Tan S, Luo H, Chen J, Chen JD, Huizinga JD. Intraluminal pressure patterns in the human colon assessed by high-resolution manometry. Sci Rep. 2017 Feb 20;7:41436. doi: 10.1038/srep41436. 14.Cheng D, Lu XH, Li M, Luo HS, Yuan JP, Zhang HD, Tan SY. [Primary diffuse large B-cell lymphoma in the liver: a case report]. Zhonghua Gan Zang Bing Za Zhi. 2016 Sep 20;24(9):699-700. doi: 10.3760/cma.j.issn.1007-3418. 15.Rahman K, Desai C, Iyer SS, Thorn NE, Kumar P, Liu Y, Smith T, Neish AS, Li H, Tan S, Wu P, Liu X, Yu Y, Farris AB, Nusrat A, Parkos CA, Anania FA. Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol. Gastroenterology. 2016 Oct;151(4):733-746.e12. doi: 10.1053/j.gastro.2016.06.022. 16.Wu P, Hua Y, Tan S, Li M, Yongxiang S, Fang G. Interactions of smoking with rs833061 polymorphism on the risk of non-alcoholic fat liver disease in Hubei Han population: a preliminary case-control study. Iran J Basic Med Sci. 2015 Nov;18(11):1112-7. 17. Li H, Chen JH, Yang Z, Huang M, Yu Y, Tan S, Luo H, Huizinga JD. Neurotensin Changes Propulsive Activity into a Segmental Motor Pattern in the Rat Colon. J Neurogastroenterol Motil. 2016 Jul 30;22(3):517-28. doi: 10.5056/jnm15181. 18.Wu P, Shu Y, Li M, Luo H, Zhang G, Tan S. [Study on the interaction between matrix metalloproteinases gene polymorphism and central obesity in nonalcoholic fatty liver disease]. Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Dec;36(12):1415-8. 19.Wu PB, Dai JF, Wang Q, Zhang G, Tan SY, Li M, Ye HL. Association between NCF4 rs4821544T/C polymorphism and inflammatory bowel disease risk in Caucasian: a meta-analysis. Inflamm Res. 2015 Oct;64(10):825-31. doi:10.1007/s00011-015-0866-1. 20.Wu P, Hua Y, Tan S, Li M, Shu Y, Fang G. Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study. Int J Clin Exp Pathol. 2015 Apr 1;8(4):4165-70. |
武汉大学人民医院
湖北省人民医院