范翠芳
妇产科
产科主任，教授，三级主任医师，硕士生导师
产科主任，教授，三级主任医师，硕士生导师
导师介绍
| 姓名 | 范翠芳 |
| 出生年月 | 1967年10月 |
| 单位 | 武汉大学人民医院妇产科 |
| 所属学科 | 临床医学-妇产学 |
| 职务、职称及头衔 | 产科主任，教授，三级主任医师，硕士生导师 |
| 359568292@qq.com | |
| 联系方式 | 13971050592 |
| 研究方向 |
1.围产医学 2.母胎医学 |
| 个人简介 |
从事妇产科工作30年，对产科常见病多发病积累了丰富的经验，亲和力好。擅长高危妊娠的诊断和处理，特别擅长妊娠高血压疾病、妊娠期糖尿病的诊治；另一方面擅长胎儿医学中的宫内诊断和宫内治疗。剖宫产手术、助产技术、产科急救技术及宫颈环扎手术等技术娴熟，成功救治了无数孕产妇和围产儿。 科研方面：先后获得全国妇幼健康科学技术一等奖，省市科学技术进步奖二、三等奖三项，多项研究成果经鉴定达到国际先进水平。作为骨干成员参与到“十四·五”国家重点攻关的前沿技术研究计划，主持和参与国家级及湖北省自然科学基金项目多项。以第一作者或通讯作者发表论文30余篇，近5年发表SCI论文20余篇。 |
| 学术任职与荣誉 |
中国医师协会医学遗传医师分会常务委员 中国妇幼保健协会妊娠合并糖尿病专业委员会常务委员 中国医师协会妇产科医师分会第二届委员会妇产科委员会常委 中华医学继续教育委员会副主任委员 湖北省医学生物免疫学会母胎医学专业委员会副主任委员 中国精准医疗分会遗传疾病专业委员会理事 中华预防医学会生命早期发育与疾病预防专业委员会常务委员 湖北省及武汉市医学会医疗事故技术鉴定专家 |
| 教育履历 |
1985.09-1990.06,武汉大学,临床医学专业,本科,学士学位 1998.08-2001.06,华中科技大学,中西结合基础专业，硕士学位 2011.09-2015.12,武汉大学,妇幼健康专业，博士学位 |
| 工作履历 |
1990.07-2003.03,华中科技大学附属荆州医院,住院医师 2003.4-2010.4，华中科技大学附属荆州医院，妇产科副主任 2010.05-2018.5,武汉大学人民医院,主任医师 2018.06-至今，武汉大学人民医院，产科主任 |
| 成果获奖 |
1）全国妇幼健康科学技术一等奖 2）《缺血再灌注对多脏器损失影响的机制与防治探讨》2011年获湖北省科技进步二等奖； 3）湖北省科技进步三等奖2项； 4）武汉市科技进步二等奖1项； 5）荆州市科技进步三等奖1项； |
| 代表性论著 |
1.Fan
C, Lei D, Fang C, Li C, Wang M, Liu Y, Bao Y, Sun Y, Huang J, Guo Y, Yu Y,
Wang S. Perinatal Transmission of 2019 Coronavirus Disease-Associated Severe
Acute Respiratory Syndrome Coronavirus 2: Should We Worry? Clin Infect Dis.
2021 Mar 1;72(5):862-864. (SCI一区) 2.Yan J, Guo J, Fan C, Juan J, Yu X, Li J, Feng L, Li C, Chen H, Qiao Y, Lei D, Wang C, Xiong G, Xiao F, He W, Pang Q, Hu X, Wang S, Chen D, Zhang Y, Poon LC, Yang H. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol. 2020 Jul;223(1):111.e1-111.e14. (SCI一区) 3.雷帝;王晨;李春燕;方聪聪;杨文兵;程苾恒;魏敏;徐晓宇;杨慧霞;王素青;范翠芳*. (2020.03).妊娠合并新型冠状病毒肺炎九例临床分析.中华围产医学杂志. (北大核心期刊，159-165) 4.Lei D, Deng N, Wang S, Huang J, Fan C. Upregulated ARRDC3 limits trophoblast cell invasion and tube formation and is associated with preeclampsia. Placenta. 2020 Jan 1;89:10-19. (SCI三区) 5.Pang H, Lei D, Guo Y, Yu Y, Liu T, Liu Y, Chen T, Fan C. Three categories of similarities between the placenta and cancer that can aid cancer treatment: Cells, the microenvironment, and metabolites. Front Oncol. 2022 Aug 18;12:977618.（SCI三区） 6.Li H, Nawsherwan, Fan C, Mubarik S, Nabi G, Ping YX. The trend in delayed childbearing and its potential consequences on pregnancy outcomes: a single center 9-years retrospective cohort study in Hubei, China. BMC Pregnancy Childbirth. 2022 Jun 24;22(1):514. SCI三区 7.Li H, Nawsherwan, Fan C, Yin S, Haq IU, Mubarik S, Nabi G, Khan S, Hua L. Changes in adverse pregnancy outcomes in women with advanced maternal age (AMA) after the enactment of China's universal two-child policy. Sci Rep. 2022 Mar 23;12(1):5048.SCI三区 8.Zhang Q, Zhang K, Guo Y, Wei X, Sun Y, Cai B, Shi Y, Du Y, Liu Y, Fan C, Zhao XZ. The isolation and analysis of fetal nucleated red blood cells using multifunctional microbeads with a nanostructured coating toward early noninvasive prenatal diagnostics. J Mater Chem B. 2021 Apr 7;9(13):3047-3054. SCI二区 9.Huang Q, Gong M, Tan T, Lin Y, Bao Y, Fan C. Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomal MicroRNA-18b-3p Inhibits the Occurrence of Preeclampsia by Targeting LEP. Nanoscale Res Lett. 2021 Feb 10;16(1):27.（SCI一区） 10.Lei D, Fang C, Deng N, Yao B, Fan C. Long noncoding RNA expression profiling identifies MIR210HG as a novel molecule in severe preeclampsia. Life Sci. 2021 Apr 1;270:119121.（SCI二区） 11. Wu L, Liu Q, Fan C, Yi X, Cheng B. MALAT1 recruited the E3 ubiquitin ligase FBXW7 to induce CRY2 ubiquitin-mediated degradation and participated in trophoblast migration and invasion. J Cell Physiol. 2021 Mar;236(3):2169-2177.（SCI二区） 12.Pang H, Lei D, Chen T, Liu Y, Fan C. The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia. Int J Mol Sci. 2023 Mar 7;24(6):5111.（SCI二区） 13.Pang H, Lei D, Huang J, Guo Y, Fan C. Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway. Mol Cell Probes. 2023 Feb;67:101896.（SCI三区） 14.Zhang Q, Zhang K, Guo Y, Wei X, Sun Y, Cai B, Shi Y, Du Y, Liu Y, Fan C, Zhao XZ. The isolation and analysis of fetal nucleated red blood cells using multifunctional microbeads with a nanostructured coating toward early noninvasive prenatal diagnostics. J Mater Chem B. 2021 Apr 7;9(13):3047-3054.（SCI二区） 15. Li H, Nawsherwan, Fan C, Mubarik S, Nabi G, Ping YX. The trend in delayed childbearing and its potential consequences on pregnancy outcomes: a single center 9-years retrospective cohort study in Hubei, China. BMC Pregnancy Childbirth. 2022 Jun 24;22(1):514.（SCI三区） 16.Zhang J, Mo HQ, Tian FJ, Zeng WH, Liu XR, Ma XL, Li X, Qin S, Fan CF, Lin Y. EIF5A1 promotes trophoblast migration and invasion via ARAF-mediated activation of the integrin/ERK signaling pathway. Cell Death Dis. 2018 Sep 11;9(9):926.（SCI一区） |
| Name | Cuifang Fan |
| Date of birth | Oct，1967 |
| Department | Obstetrics and Gynecology，Renmin Hospital,Wuhan University. |
| Title | Director, Professor, Master tutor |
| 359568292@qq.com | |
| TEL | 13971050592 |
| Research Direction |
1.
Perinatal medicine 2. Maternal and Fetal Medicine |
| Personal Profile |
She
has been working in obstetrics and gynecology for 30 years, and has
accumulated rich experience in common obstetrics and frequently-occurring
diseases and has a good affinity. Good at diagnosis and treatment of
high-risk pregnancy, especially good at diagnosis and treatment of
pregnancy-induced hypertension and gestational diabetes; on the other hand,
he is good at intrauterine diagnosis and treatment in fetal medicine. Skilled
in cesarean section surgery, midwifery technology, obstetric first aid technology
and cervical cerclage surgery, have successfully treated countless pregnant
women and perinatal babies. Scientific research: She has won the first prize of the National Science and Technology Award for Maternal and Child Health, and the second and third prizes of the Provincial and Municipal Science and Technology Progress Awards. As a key member of the "14th Five-Year Plan" national key research program of cutting-edge technology, presided over and participated in a number of national and Hubei Provincial Natural Science Foundation projects. He has published more than 30 papers as the first author or corresponding author, and 20 SCI papers in the past 5 years. |
| Selected Publications |
1.Fan
C, Lei D, Fang C, Li C, Wang M, Liu Y, Bao Y, Sun Y, Huang J, Guo Y, Yu Y,
Wang S. Perinatal Transmission of 2019 Coronavirus Disease-Associated Severe
Acute Respiratory Syndrome Coronavirus 2: Should We Worry? Clin Infect Dis.
2021 Mar 1;72(5):862-864. Q1 2.Yan J, Guo J, Fan C, Juan J, Yu X, Li J, Feng L, Li C, Chen H, Qiao Y, Lei D, Wang C, Xiong G, Xiao F, He W, Pang Q, Hu X, Wang S, Chen D, Zhang Y, Poon LC, Yang H. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol. 2020 Jul;223(1):111.e1-111.e14. Q1 3.雷帝;王晨;李春燕;方聪聪;杨文兵;程苾恒;魏敏;徐晓宇;杨慧霞;王素青;范翠芳*. (2020.03).妊娠合并新型冠状病毒肺炎九例临床分析.中华围产医学杂志. (北大核心期刊，159-165) 4.Lei D, Deng N, Wang S, Huang J, Fan C. Upregulated ARRDC3 limits trophoblast cell invasion and tube formation and is associated with preeclampsia. Placenta. 2020 Jan 1;89:10-19. Q3 5.Pang H, Lei D, Guo Y, Yu Y, Liu T, Liu Y, Chen T, Fan C. Three categories of similarities between the placenta and cancer that can aid cancer treatment: Cells, the microenvironment, and metabolites. Front Oncol. 2022 Aug 18;12:977618.Q3 6.Li H, Nawsherwan, Fan C, Mubarik S, Nabi G, Ping YX. The trend in delayed childbearing and its potential consequences on pregnancy outcomes: a single center 9-years retrospective cohort study in Hubei, China. BMC Pregnancy Childbirth. 2022 Jun 24;22(1):514. Q3 7.Li H, Nawsherwan, Fan C, Yin S, Haq IU, Mubarik S, Nabi G, Khan S, Hua L. Changes in adverse pregnancy outcomes in women with advanced maternal age (AMA) after the enactment of China's universal two-child policy. Sci Rep. 2022 Mar 23;12(1):5048.Q3 8.Zhang Q, Zhang K, Guo Y, Wei X, Sun Y, Cai B, Shi Y, Du Y, Liu Y, Fan C, Zhao XZ. The isolation and analysis of fetal nucleated red blood cells using multifunctional microbeads with a nanostructured coating toward early noninvasive prenatal diagnostics. J Mater Chem B. 2021 Apr 7;9(13):3047-3054. Q2 9.Huang Q, Gong M, Tan T, Lin Y, Bao Y, Fan C. Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomal MicroRNA-18b-3p Inhibits the Occurrence of Preeclampsia by Targeting LEP. Nanoscale Res Lett. 2021 Feb 10;16(1):27. Q1 10.Lei D, Fang C, Deng N, Yao B, Fan C. Long noncoding RNA expression profiling identifies MIR210HG as a novel molecule in severe preeclampsia. Life Sci. 2021 Apr 1;270:119121.Q2 11. Wu L, Liu Q, Fan C, Yi X, Cheng B. MALAT1 recruited the E3 ubiquitin ligase FBXW7 to induce CRY2 ubiquitin-mediated degradation and participated in trophoblast migration and invasion. J Cell Physiol. 2021 Mar;236(3):2169-2177.Q2 12.Pang H, Lei D, Chen T, Liu Y, Fan C. The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia. Int J Mol Sci. 2023 Mar 7;24(6):5111. Q2 13.Pang H, Lei D, Huang J, Guo Y, Fan C. Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway. Mol Cell Probes. 2023 Feb;67:101896.Q3 14.Zhang Q, Zhang K, Guo Y, Wei X, Sun Y, Cai B, Shi Y, Du Y, Liu Y, Fan C, Zhao XZ. The isolation and analysis of fetal nucleated red blood cells using multifunctional microbeads with a nanostructured coating toward early noninvasive prenatal diagnostics. J Mater Chem B. 2021 Apr 7;9(13):3047-3054.Q2 15. Li H, Nawsherwan, Fan C, Mubarik S, Nabi G, Ping YX. The trend in delayed childbearing and its potential consequences on pregnancy outcomes: a single center 9-years retrospective cohort study in Hubei, China. BMC Pregnancy Childbirth. 2022 Jun 24;22(1):514. Q3 16.Zhang J, Mo HQ, Tian FJ, Zeng WH, Liu XR, Ma XL, Li X, Qin S, Fan CF, Lin Y. EIF5A1 promotes trophoblast migration and invasion via ARAF-mediated activation of the integrin/ERK signaling pathway. Cell Death Dis. 2018 Sep 11;9(9):926. Q1 |
武汉大学人民医院
湖北省人民医院