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姓名
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程艳香
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出生年月
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1974年1月
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单位
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武汉大学人民医院妇产科
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所属学科
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临床医学-妇产科学
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职务、职称及头衔
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东院妇科科主任，教授/二级主任医师，博士生导师
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E-mail
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yanxiangCheng@whu.edu.cn
rm001050@whu.edu.cn
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联系方式
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027-88041911转83361
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研究方向
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1.妊娠相关疾病
2.排卵障碍性疾病
3.妇科肿瘤
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个人简介
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主要研究方向为妊娠相关性疾病、排卵障碍性疾病、妇科肿瘤等的基础和临床研究。先后承担并主持国家自然科学基金3项，国家重点项目子课题1项，湖北省重点课题2项，及其他省部级、厅级、教育部等科研课题13项，教学课题8项；在国内外专业期刊发表论文120余篇，其中SCI文章80余篇，其中一区8篇，二区24篇。主编妇产科专著2部。发明专利2项。先后获得湖北省科技进步一等奖（排7）、二等奖（排1）和三等奖（排1）各一次。
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学术任职与荣誉
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学术任职：
1.生育力保护与保存专业委员会常委
2.武汉市医学会妇产科分会常委
3.全国卫生产业企业管理协会妇科智能诊疗分会常委
4.中国妇幼保健协会妇女儿童健康素养促进工作委员会常委
5.湖北省医学会妇产科分会常委
6.中国医药教育协会整形美容外科专委会常委
7.中国医药教育协会肿瘤临床科研创新发展专委会常委
8.武汉生物工程学会理事
9.女性生物治疗促进盆腔健康专业委员会主任委员
荣誉：
1. 2023年获湖北省科技进步二等奖，反复妊娠失败的诊疗策略和技术创新，排1
2. 2022年武汉大学人民医院“核心人才杰出贡献奖”
3. 2021年武汉大学人民医院“核心人才杰出贡献奖”
4. 2020年武汉大学人民医院“核心人才杰出贡献奖”
5. 2020年中国康复医学会新冠疫情防控先进个人
6. 2020年武汉大学人民医院“抗疫英雄”
7. 2019年湖北省科技进步奖三等奖 常见妇科肿瘤发病机制与靶向阻断 排1
8. 2019年度武汉大学人民医院“先进工作者”称号
9. 2018年度“慈善中国行”优秀医务工作者
10. 2018年度荣获武汉大学优秀班级导师称号
11. 2018年度荣获武汉大学人民医院优秀规培老师称号
12. 2018年度荣获武汉大学人民医院“先进工作者”称号
13. 2017年度荣获“胡润-平安中国好医生”称号
14. 2016年荣获武汉大学人民医院“核心人才奖”的荣誉称号
15. 2009年度湖北省科技进步奖一等奖，女性盆底功能障碍性疾病的发病基础和手术治疗研究 排7
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教育履历
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2015.12-2016.12美国宾夕法尼亚大学，访问学者
2003.09-2008.06华中科技大学同济医院妇产科，硕博士，濮德敏（导师）
1993.09-1998.06，武汉大学医学院，临床医学，本科
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工作履历
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2020/11-至今，武汉大学人民医院，教授/主任医师
2018/10-至今，武汉大学人民医院，东院妇科科主任
2016/11-至今，武汉大学人民医院，妇产科，主任医师
2015/12-2016/12，美国宾夕法尼亚大学，访问学者
2011/10-2016/10，武汉大学人民医院，妇产科，副主任医师
2008/07-2011/09，武汉大学人民医院，妇产科，主治医师
1998/07-2003/08，湖北省仙桃市第一人民医院，妇产科，住院及主治医师
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成果获奖
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1.《反复妊娠失败的诊疗策略和技术创新》2023年湖北省科技进步奖二等奖
2.《常见妇科肿瘤发病机制与靶向阻断》2019年湖北省科技进步奖三等奖
3.《女性盆底功能障碍性疾病的发病基础和手术治疗研究》2009年湖北省科技进步一等奖
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代表性论著
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1.
Fangfang Dai#, Ruiqi Wang #, Zhimin Deng #, Dongyong Yang, Linlin Wang, Mali
Wu , Wei Hu*, Yanxiang Cheng*. Comparison of the different animal modeling
and therapy methods of premature ovarian failure in animal model. Stem Cell
Res Ther. 2023 May 18;14(1):135. (IF:8.079) (中科院大类分区:2区)
2. Yuwei Zhang#, Fangfang Dai#, Dongyong Yang, Yajing Zheng, Ronghui Zhu,
Mali Wu, Zhimin Deng, Zitao Wang, Wei Tan, Zhidian Li, Bingshu Li*, Ling
Gao*, Yanxiang Cheng*. Deletion of Insulin-like growth factor II mRNA-binding
protein 3 participates in the pathogenesis of recurrent spontaneous abortion
by inhibiting IL-10 secretion and inducing M1 polarization. International
Immunopharmacology 114 (2023) 109473. (IF:5.741) (中科院大类分区:医学2区)
3. Wei Tan#, Fangfang Dai#, Dongyong Yang, Zhimin Deng, Ran Gu', Xiaomiao
Zhao* and Yanxiang Cheng*. MiR-93-5p promotes granulosa cell apoptosis and
ferroptosis by the NF-kB signaling pathway in polycystic ovary syndrome.
Frontiers in Immunology. 2022 Oct 19;13:967151. (IF:8.786)(中科院大类分区:医学2区)
4.Yajing Zheng#, Juan He #, Dongyong Yang #,
Mengqin Yuan, Shiyi Liu, Fangfang Dai*, Yifan Jia*, Yanxiang Cheng*. Irisin
reduces the abnormal reproductive and metabolic phenotypes of PCOS by
regulating the activity of brown adipose tissue in mice. Biol Reprod. 2022
Jun 17:ioac125. (IF:4.161) (中科院大类分区:医学2区)
5. Ronghui Zhu#, Fangfang Dai#, Dongyong Yang, Shiyi Liu, Yajing Zheng,
Mali Wu, Zhimin Deng, Zitao Wang, Yuwei Zhang, Wei Tan, Zhidian Li, Juan HE,
Xiao Yang*, Min Hu*, Yanxiang Cheng*. The mechanism of Insulin-like growth
factor II mRNA-binging protein 3 induce decidualization and maternal-fetal
interface cross-talk by TGF-β1 in recurrent spontaneous abortion. Front Cell
Dev Biol. 2022 Apr 8;10:862180. (IF:6.081) (中科院大类分区:生物2区)
6. Longfei Chen#, Yantong Liu#, Hongshan Xu, Linlu Ma, Yifan Wang, Le Yu,
Fang Wang, Jiaomeng Zhu, Xuejia Hu, Kezhen Yi, Yi Yang*, Hui Shen, Fuling
Zhou*, Xiaoqi Gao, Yanxiang Cheng*, Long Bai, Yongwei Duan, Fubing Wang,
Yimin Zhu. Touchable cell biophysics property recognition platforms enable
multifunctional blood smart health care. Microsyst Nanoeng. 2021 Dec
8;7:103.(IF:8.006)(中科院大类分区:工程技术1区)
7. Longfei Chen#, Yajing Zheng#, Yantong Liu, Pengfu Tian, Le Yu, Long Bai,
Fuling Zhou, Yi Yang, * Yanxiang Cheng,* Fubing Wang, Li Zheng, Fenghua Jiang
and Yimin Zhu. Microfluidic-based in vitro thrombosis model for studying
microplastics toxicity. Lab Chip. 2022 Feb 18; (IF:7.517)(中科院大类分区:工程技术1区)
8. Mengqin Yuan#, Min Hu#, Fangfang Dai, Yaqi Fan, Zhimin Deng, Hongbing
Deng*, Yanxiang Cheng*. Application of synthetic and natural polymers in
surgical mesh for pelvic floor reconstruction. Materials & Design 209
(2021) 109984. (IF:9.417) (中科院大类分区:材料科学1区)
9. Zhimin Deng#, Fangfang Dai#, Quan Zhou*, Yanxiang Cheng*.
Hsa_circ_0000301 facilitates the progression of cervical cancer by targeting
miR-1228-3p/IRF4 Axis[J]. BMC Cancer. 2021. (IF:4.638) (中科院大类分区:医学2区)
10. Fangfang Dai#, Jia Yu#, Mengqin Yuan, Zhimin Deng, Yanqing Wang, Yaqi
Fan, Hongbing Deng*, Yanxiang Cheng*. Enhanced Cellular Compatibility of
Chitosan/Collagen Multilayers LBL Modified Nanofibrous Mats. [J]. Materials
and Design, 2021. (205). (IF:9.417) (中科院大类分区:材料科学1区)
11. Dongyong Yang#, Yanqing Wang#, Yajing Zheng, Fangfang Dai, Shiyi Liu,
Mengqin Yuan, Zhimin Deng, Anyu Bao*, Yanxiang Cheng*. Silencing of lncRNA
UCA1 inhibited the pathological progression in PCOS mice through the
regulation of PI3K/AKT signaling pathway. Journal of Ovarian Research. 2021
Mar 20;14(1):48. (IF:5.506) (中科院大类分区:医学3区)
12. Li Zhang#, Yanqing Wang, Xiao Yang, Shiyi Liu, Mengqin Yuan, Shu Xian,
Dongyong Yang, Yajing Zheng, Yanxiang Cheng*. Exosomes secreted by
chemoresistant ovarian cancer cells promote angiogenesis. Journal of Ovarian
Research. 2021 Jan 7;14(1):7. (IF:5.506) (中科院大类分区:医学3区)
13. Shu Xian#, Yan Zhang#, Li Wang, Fang Yao, Jinli Ding, Yanqing Wang,
Xiao Yang, Fangfang Dai, Tailang Yin*, Yanxiang Cheng*. INO80 participates in
the pathogenesis of recurrent miscarriage by epigenetically regulating
trophoblast migration and invasion. Journal Of Cellular And Molecular
Medicine. 2021 Mar 16. (IF:5.295) (中科院大类分区:医学2区)
14. Min Tan#, Yanxiang Cheng#, Xiaozhu Zhong, Dongyong Yang, Sushi Jiang,
Yang Ye, Miao Ding, Guijun Guan, Dongzi Yang*, Xiaomiao Zhao*. LNK promotes
granulosa cell apoptosis in PCOS via negatively regulating insulin-stimulated
AKT-FOXO3 pathway. Aging us. 2020.12. (IF:5.955) (中科院大类分区:医学2区)
15. Xuelei Shi#, Yanxiang Cheng#, Jian Wang, Haoxiang Chen, Xiaocheng Wang,
Xinghuan Li, Weihong Tan, Zhikai Tan*. 3D printed intelligent scaffold
prevents recurrence and distal metastasis of breast cancer[J]. Theranostics.
2020;10(23): 10652-10664. (IF:11.6) (中科院大类分区:医学1区TOP)
16. Fenghua Tao#, Yanxiang Cheng#, Hai Tao, Lin Jin, Zhihui Wan, Fangfang
Dai, Wei Xiang*, Hongbing Deng*. Carboxymethyl chitosan/sodium alginate-based
micron-fibers fabricated by emulsion electrospinning for periosteal tissue
engineering[J]. Materials and Design, 2020, 194:108849. (IF:9.417) (中科院大类分区:材料科学1区Top期刊)
17. Mengqin Yuan#, Fangfang Dai, Dan Li, Yaqi Fan, Wei Xiang, Fenghua Tao,
Yanxiang Cheng*, Hongbing Deng*. Lysozyme/collagen multilayers layer-by-layer
deposited nanofibers with enhanced biocompatibility and antibacterial
activity[J]. Materials Science and Engineering: C. 2020, 112:110868.
(IF:8.457) (中科院大类分区:工程技术1区)
18. Dongyong Yang#, Jinli Ding#, Yanqing Wang, Mengqin Yuan, Shu Xian, Li
Zhang, Shiyi Liu, Fangfang Dai, Feiyan Wang, Yajing Zheng, Xin Zhao, Shu-jie
Liao*, Yanxiang Cheng*. YY1-PVT1 affects trophoblast invasion and adhesion by
regulating mTOR pathway-mediated autophagy[J]. Journal of Cellular Physiology
2020;235(10):6637-6646. (IF:6.513) (中科院大类分区:生物2区)
19. Fenghua Tao#, Yanxiang Cheng#, Xiaowen Shi, Huifeng Zheng, Yumin Du,
Wei Xiang*, Hongbing Deng*. Applications of chitin and chitosan nanofibers in
bone regenerative engineering[J]. Carbohydrate polymers 2020, 15(230):
115658. (IF:10.723) (中科院大类分区:化学1区，TOP期刊)
20. QianFang Meng#, Yanxiang Cheng#, *, Qinqin Huang, Minghui Zan, Wei Xie,
Yuesun, Rui Li, Xiaoyun Wei, Shishang Guo, Xingzhong Zhao, Lang Rao*, Wei
Liu*. Biomimetic Immunomagnetic Nanoparticles with Minimal Nonspecific
Biomolecule Adsorption for Enhanced Isolation of Circulating Tumor Cells[J].
ACS Applied Materials & Interfaces 2019, 11: 28732-28739. (IF:10.383) (中科院大类分区:材料科学2区，TOP期刊)
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Name
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YANXIANG CHENG
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Date of birth
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Jan, 1974
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Department
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Gynaecology And
Obstetrics Department, Renmin Hospital,Wuhan University
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Title
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Director, Professor,
doctoral tutor
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Email
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yanxiangCheng@whu.edu.cn
rm001050@whu.edu.cn
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TEL
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027-88041911-83361
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Research
Direction
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1.
Pregnancy related diseases
2. Ovulation disorders
3. Gynecological tumors
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Personal
Profile
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Her main research
interests are basic and clinical research on pregnancy-related diseases,
ovulation disorders, and gynecological tumors. She has undertaken and
presided over 3 National Natural Science Foundation of China, 1 sub-project
of National Key Project, 2 key projects of Hubei Province, 13 other
scientific research projects at the provincial and ministerial level,
department level, and Ministry of Education, and 8 teaching projects. She has
published more than 120 papers in professional journals at home and abroad,
including more than 80 SCI articles, including 8 in Region I and 24 in Region
II. She is the chief editor of 2 monographs on obstetrics and gynecology and
has 2 invention patents. And she has won the first prize of Hubei Province
Science and Technology Progress Award (ranked 7), the second prize (ranked 1)
and the third prize (ranked 1) once.
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Selected
Publications
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1.
Fangfang Dai#, Ruiqi Wang #, Zhimin Deng #, Dongyong Yang, Linlin Wang, Mali
Wu , Wei Hu*, Yanxiang Cheng*. Comparison of the different animal modeling
and therapy methods of premature ovarian failure in animal model. Stem Cell
Res Ther. 2023 May 18;14(1):135. (IF:8.079) (中科院大类分区:2区)
2. Yuwei Zhang#, Fangfang Dai#, Dongyong Yang, Yajing Zheng, Ronghui Zhu,
Mali Wu, Zhimin Deng, Zitao Wang, Wei Tan, Zhidian Li, Bingshu Li*, Ling
Gao*, Yanxiang Cheng*. Deletion of Insulin-like growth factor II mRNA-binding
protein 3 participates in the pathogenesis of recurrent spontaneous abortion
by inhibiting IL-10 secretion and inducing M1 polarization. International
Immunopharmacology 114 (2023) 109473. (IF:5.741) (中科院大类分区:医学2区)
3. Wei Tan#, Fangfang Dai#, Dongyong Yang, Zhimin Deng, Ran Gu', Xiaomiao
Zhao* and Yanxiang Cheng*. MiR-93-5p promotes granulosa cell apoptosis and
ferroptosis by the NF-kB signaling pathway in polycystic ovary syndrome.
Frontiers in Immunology. 2022 Oct 19;13:967151. (IF:8.786)(中科院大类分区:医学2区)
4.Yajing Zheng#, Juan He #, Dongyong Yang #,
Mengqin Yuan, Shiyi Liu, Fangfang Dai*, Yifan Jia*, Yanxiang Cheng*. Irisin
reduces the abnormal reproductive and metabolic phenotypes of PCOS by
regulating the activity of brown adipose tissue in mice. Biol Reprod. 2022
Jun 17:ioac125. (IF:4.161) (中科院大类分区:医学2区)
5. Ronghui Zhu#, Fangfang Dai#, Dongyong Yang, Shiyi Liu, Yajing Zheng,
Mali Wu, Zhimin Deng, Zitao Wang, Yuwei Zhang, Wei Tan, Zhidian Li, Juan HE,
Xiao Yang*, Min Hu*, Yanxiang Cheng*. The mechanism of Insulin-like growth
factor II mRNA-binging protein 3 induce decidualization and maternal-fetal
interface cross-talk by TGF-β1 in recurrent spontaneous abortion. Front Cell
Dev Biol. 2022 Apr 8;10:862180. (IF:6.081) (中科院大类分区:生物2区)
6. Longfei Chen#, Yantong Liu#, Hongshan Xu, Linlu Ma, Yifan Wang, Le Yu,
Fang Wang, Jiaomeng Zhu, Xuejia Hu, Kezhen Yi, Yi Yang*, Hui Shen, Fuling
Zhou*, Xiaoqi Gao, Yanxiang Cheng*, Long Bai, Yongwei Duan, Fubing Wang,
Yimin Zhu. Touchable cell biophysics property recognition platforms enable
multifunctional blood smart health care. Microsyst Nanoeng. 2021 Dec
8;7:103.(IF:8.006)(中科院大类分区:工程技术1区)
7. Longfei Chen#, Yajing Zheng#, Yantong Liu, Pengfu Tian, Le Yu, Long Bai,
Fuling Zhou, Yi Yang, * Yanxiang Cheng,* Fubing Wang, Li Zheng, Fenghua Jiang
and Yimin Zhu. Microfluidic-based in vitro thrombosis model for studying
microplastics toxicity. Lab Chip. 2022 Feb 18; (IF:7.517)(中科院大类分区:工程技术1区)
8. Mengqin Yuan#, Min Hu#, Fangfang Dai, Yaqi Fan, Zhimin Deng, Hongbing
Deng*, Yanxiang Cheng*. Application of synthetic and natural polymers in
surgical mesh for pelvic floor reconstruction. Materials & Design 209
(2021) 109984. (IF:9.417) (中科院大类分区:材料科学1区)
9. Zhimin Deng#, Fangfang Dai#, Quan Zhou*, Yanxiang Cheng*.
Hsa_circ_0000301 facilitates the progression of cervical cancer by targeting
miR-1228-3p/IRF4 Axis[J]. BMC Cancer. 2021. (IF:4.638) (中科院大类分区:医学2区)
10. Fangfang Dai#, Jia Yu#, Mengqin Yuan, Zhimin Deng, Yanqing Wang, Yaqi
Fan, Hongbing Deng*, Yanxiang Cheng*. Enhanced Cellular Compatibility of
Chitosan/Collagen Multilayers LBL Modified Nanofibrous Mats. [J]. Materials
and Design, 2021. (205). (IF:9.417) (中科院大类分区:材料科学1区)
11. Dongyong Yang#, Yanqing Wang#, Yajing Zheng, Fangfang Dai, Shiyi Liu,
Mengqin Yuan, Zhimin Deng, Anyu Bao*, Yanxiang Cheng*. Silencing of lncRNA
UCA1 inhibited the pathological progression in PCOS mice through the
regulation of PI3K/AKT signaling pathway. Journal of Ovarian Research. 2021
Mar 20;14(1):48. (IF:5.506) (中科院大类分区:医学3区)
12. Li Zhang#, Yanqing Wang, Xiao Yang, Shiyi Liu, Mengqin Yuan, Shu Xian,
Dongyong Yang, Yajing Zheng, Yanxiang Cheng*. Exosomes secreted by
chemoresistant ovarian cancer cells promote angiogenesis. Journal of Ovarian
Research. 2021 Jan 7;14(1):7. (IF:5.506) (中科院大类分区:医学3区)
13. Shu Xian#, Yan Zhang#, Li Wang, Fang Yao, Jinli Ding, Yanqing Wang,
Xiao Yang, Fangfang Dai, Tailang Yin*, Yanxiang Cheng*. INO80 participates in
the pathogenesis of recurrent miscarriage by epigenetically regulating
trophoblast migration and invasion. Journal Of Cellular And Molecular
Medicine. 2021 Mar 16. (IF:5.295) (中科院大类分区:医学2区)
14. Min Tan#, Yanxiang Cheng#, Xiaozhu Zhong, Dongyong Yang, Sushi Jiang,
Yang Ye, Miao Ding, Guijun Guan, Dongzi Yang*, Xiaomiao Zhao*. LNK promotes
granulosa cell apoptosis in PCOS via negatively regulating insulin-stimulated
AKT-FOXO3 pathway. Aging us. 2020.12. (IF:5.955) (中科院大类分区:医学2区)
15. Xuelei Shi#, Yanxiang Cheng#, Jian Wang, Haoxiang Chen, Xiaocheng Wang,
Xinghuan Li, Weihong Tan, Zhikai Tan*. 3D printed intelligent scaffold
prevents recurrence and distal metastasis of breast cancer[J]. Theranostics.
2020;10(23): 10652-10664. (IF:11.6) (中科院大类分区:医学1区TOP)
16. Fenghua Tao#, Yanxiang Cheng#, Hai Tao, Lin Jin, Zhihui Wan, Fangfang
Dai, Wei Xiang*, Hongbing Deng*. Carboxymethyl chitosan/sodium alginate-based
micron-fibers fabricated by emulsion electrospinning for periosteal tissue
engineering[J]. Materials and Design, 2020, 194:108849. (IF:9.417) (中科院大类分区:材料科学1区Top期刊)
17. Mengqin Yuan#, Fangfang Dai, Dan Li, Yaqi Fan, Wei Xiang, Fenghua Tao,
Yanxiang Cheng*, Hongbing Deng*. Lysozyme/collagen multilayers layer-by-layer
deposited nanofibers with enhanced biocompatibility and antibacterial
activity[J]. Materials Science and Engineering: C. 2020, 112:110868.
(IF:8.457) (中科院大类分区:工程技术1区)
18. Dongyong Yang#, Jinli Ding#, Yanqing Wang, Mengqin Yuan, Shu Xian, Li
Zhang, Shiyi Liu, Fangfang Dai, Feiyan Wang, Yajing Zheng, Xin Zhao, Shu-jie
Liao*, Yanxiang Cheng*. YY1-PVT1 affects trophoblast invasion and adhesion by
regulating mTOR pathway-mediated autophagy[J]. Journal of Cellular Physiology
2020;235(10):6637-6646. (IF:6.513) (中科院大类分区:生物2区)
19. Fenghua Tao#, Yanxiang Cheng#, Xiaowen Shi, Huifeng Zheng, Yumin Du,
Wei Xiang*, Hongbing Deng*. Applications of chitin and chitosan nanofibers in
bone regenerative engineering[J]. Carbohydrate polymers 2020, 15(230):
115658. (IF:10.723) (中科院大类分区:化学1区，TOP期刊)
20. QianFang Meng#, Yanxiang Cheng#, *, Qinqin Huang, Minghui Zan, Wei Xie,
Yuesun, Rui Li, Xiaoyun Wei, Shishang Guo, Xingzhong Zhao, Lang Rao*, Wei
Liu*. Biomimetic Immunomagnetic Nanoparticles with Minimal Nonspecific
Biomolecule Adsorption for Enhanced Isolation of Circulating Tumor Cells[J].
ACS Applied Materials & Interfaces 2019, 11: 28732-28739. (IF:10.383) (中科院大类分区:材料科学2区，TOP期刊)
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武汉大学人民医院
湖北省人民医院