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  • 刘育 心内
    主任医师,副教授,硕士生导师
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    导师介绍

    姓名 刘育
    出生年月 1983年5月
    单位 武汉大学人民医院心血管内科
    所属学科 临床医学-内科学
    职务、职称及头衔 主任医师,副教授,硕士生导师
    E-mail liuyuwuda@163.com
    联系方式 027-88041911转81038或13995607375
    研究方向 室性心律失常的调控机制与防治研究
    个人简介 主要从事心血管疾病的诊治与科研工作,主持国家自然科学基金2项、湖北省自然科学基金1项、武汉市青年科技晨光计划1项、武汉大学自主科研项目1项。以第一作者或通讯作者在JACC Cardiovasc Interv、Hypertension 、Cardiovasc Res、Europace、J Cardiovasc Electrophysiol等杂志发表论文40余篇,其中SCI论文30余篇。为湖北省科学技术协会“科技创新源泉工程”创新创业人才、武汉市中青年医学骨干人才、武汉大学珞珈青年学者、武汉大学人民医院第四轮青年重点人才。已培养硕士生2名,目前正在培养硕士生2名。
    学术任职与荣誉 中华医学会心电生理与起搏分会青年委员会副主任委员
    中华医学会心电生理和起搏分会中青年电生理工作委员会常委委员兼秘书
    中华医学会心电生理和起搏分会室性心律失常工作委员会委员
    中华医学会心电生理和起搏分会左心耳封堵工作委员会委员兼秘书
    中华医学会心电生理和起搏分会创新工作委员会委员                              中华医学会心电生理和起搏分会心脏性猝死预防工作委员会委员                     《中国心脏起搏与心电生理杂志》特邀审稿人
    教育履历 2000.09-2005.06武汉大学临床医学专业本科生         获学士学位
    2005.09-2007.06武汉大学第一临床学院内科学硕士研究生获硕士学位
    2007.09-2010.06武汉大学第一临床学院内科学博士研究生获博士学位
    工作履历 2010.07-2010.12 武汉大学人民医院心血管内科住院医师
    2010.09-2011.09 美国Oklahoma大学健康科学中心访问学者
    2011.01-2012.12 武汉大学人民医院心血管内科主治医师
    2013.01-2013.12 武汉大学人民医院心血管内科副主任医师
    2014.01-2017.12 武汉大学人民医院心血管内科副主任医师、副教授
    2018.01-至今      武汉大学人民医院心血管内科主任医师、副教授
    成果获奖 1.《复杂升弓部大血管手术技术创新与临床推广应用》2019年获湖北省科技成果推广二等奖                                                                                                                                                  2.《心房颤动的防治策略研究与推广应用》2014年获湖北省科技成果推广一等奖
    3.《自主神经与心律失常相关性研究》2010年湖北省科技进步一等奖
    4.《自主神经与心律失常相关性研究》2010年武汉市科技进步一等奖
    代表性论著 1.He Y, Liu Y (corresponding author), Zhou M, Xie K, Tang Y, Huang H, Huang C. C-type natriuretic peptide suppresses ventricular arrhythmias in rats with acute myocardial ischemia. Peptides. 2020 Apr;126:170238.
    2.Zhou M, Liu Y (corresponding author), He Y, Xie K, Quan D, Tang Y, Huang H, Huang C. Selective chemical ablation of transient receptor potential vanilloid 1 expressing neurons in the left stellate ganglion protects against ischemia-induced ventricular arrhythmias in dogs. Biomed Pharmacother. 2019 Dec;120:109500.
    3.Zhou M, Liu Y (corresponding author), Xiong L, Quan D, He Y, Tang Y, Huang H, Huang C. Cardiac Sympathetic Afferent Denervation Protects Against Ventricular Arrhythmias by Modulating Cardiac Sympathetic Nerve Activity During Acute Myocardial Infarction. Med Sci Monit. 2019 Mar 16;25:1984-1993.
    4.Xiong L, Liu Y (corresponding author), Zhou M, Wang G, Quan D, Shen C, Shuai W, Kong B, Huang C, Huang H. Targeted ablation of cardiac sympathetic neurons improves ventricular electrical remodelling in a canine model of chronic myocardial infarction. Europace. 2018 Dec 1;20(12):2036-2044.
    5.Xiong L, Liu Y  (corresponding author), Zhou M, Wang G, Quan D, Shuai W,  Shen C, Kong B, Huang C, Huang H. Targeted ablation of cardiac sympathetic neurons attenuates adverse post-infarction remodelling and left ventricular dysfunction. Exp Physiol. 2018 Sep;103(9):1221-1229.
    6.Huang H, Liu Y (co-first author), Xu Y, Wang Z, Li Y, Cao K, Zhang S, Yang Y, Yang X, Huang D, Yu B, Su X, Wu L, Huang C. Percutaneous Left Atrial Appendage Closure With the LAmbre Device for Stroke Prevention in Atrial Fibrillation: A Prospective, Multicenter Clinical Study. JACC Cardiovasc Interv. 2017;10(21):2188-2194.
    7.Peng J, Liu Y (co-first author), Xiong X, Huang C, Mei Y, Wang Z, Tang Y, Ye J, Kong B, Liu W, Wang T, Huang H. Loss of MD1 exacerbates pressure overload-induced left ventricular structural and electrical remodelling. Sci Rep. 2017;7(1):5116.
    8.Liu Y, Scherlag BJ, Fan Y, Xia W, Huang H, Po SS. Acetylcholine-Atropine Interactions: Paradoxical Effects on Atrial Fibrillation Inducibility. J Cardiovasc Pharmacol. 2017;69(6):369-373. 
    9.Xiong X, Liu Y (co-first author), Mei Y, Peng J, Wang Z, Kong B, Zhong P, Xiong L, Quan D, Li Q, Wang G, Huang H. Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling. Sci Rep. 2017;7:41857.
    10.Wu G, Liu Y (co-first author), Huang H, Tang Y, Liu W, Mei Y, Wan N, Liu X, Huang C. SH2B1 is critical for the regulation of cardiac remodelling in response to pressure overload. Cardiovasc Res. 2015;107(2):203-15.
    11.Liu W, Liu Y (co-first author), Zhang Y, Zhu X, Zhang R, Guan L, Tang Q, Jiang H, Huang C, Huang H. MicroRNA-150 Protects Against Pressure Overload-Induced Cardiac Hypertrophy. J Cell Biochem. 2015;116(10):2166-76.
    12.Liu Y, Li H, Xia W, Yu S, Huang C, Huang H. Electrophysiological effect of rotigaptide in rabbits with heart failure. Arch Med Sci. 2014;10(2):374-80. 
    13.Zhang Y, Liu Y (co-first author), Zhu XH, Zhang XD, Jiang DS, Bian ZY, Zhang XF, Chen K, Wei X, Gao L, Zhu LH, Yang Q, Fan GC, Lau WB, Ma X, Li H. Dickkopf-3 attenuates pressure overload-induced cardiac remodelling. Cardiovasc Res. 2014;102(1):35-45.
    14.Jiang DS, Liu Y (co-first author), Zhou H, Zhang Y, Zhang XD, Zhang XF, Chen K, Gao L, Peng J, Gong H, Chen Y, Yang Q, Liu PP, Fan GC, Zou Y, Li H. Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy. Hypertension. 2014;63(4):713-22.
    15.Liu Y, Huang H, Zhang Y, Zhu XY, Zhang R, Guan LH, Tang Q, Jiang H, Huang C. Regulator of G protein signaling 3 protects against cardiac hypertrophy in mice. J Cell Biochem. 2014;115(5):977-86. 
    16.Liu Y, Jiang XL, Liu Y (co-first author), Jiang DS, Zhang Y, Zhang R, Chen Y, Yang Q, Zhang XD, Fan GC, Li H. Toll-interacting protein (Tollip) negatively regulates pressure overload-induced ventricular hypertrophy in mice. Cardiovasc Res. 2014;101(1):87-96.
    17.Liu Y, Scherlag BJ, Fan Y, Mao J, Hepler E, Varma V, Male S, Xia W, Huang H, Po SS. Experimental model of focal atrial tachycardia: clinical correlates. J Cardiovasc Electrophysiol. 2013;24(8):909-13.
    18.Liu Y, Scherlag BJ, Fan Y, Varma V, Male S, Chaudhry MA, Huang C, Po SS. Inducibility of atrial fibrillation after GP ablations and "autonomic blockade": evidence for the pathophysiological role of the nonadrenergic and noncholinergic neurotransmitters. J Cardiovasc Electrophysiol. 2013;24(2):188-95.
    19.Liu Y, Scherlag BJ, Yagi T, Patterson E, Jackman WM, Lazzara R, Po SS. Extra- and intracellular recordings from the avjunction: discerning the mechanisms for irregular ventricular responses during supraventricular arrhythmias. Acta Cardiol. 2012;67(2):221-9.
    20.Liu Y, Huang H, Xia W, Tang Y, Li H, Huang C. NADPH oxidase inhibition ameliorates cardiac dysfunction in rabbits with heart failure. Mol Cell Biochem. 2010;343(1-2):143-53.
    Name YU LIU
    Date of birth May,1983 
    Department Cardiovascular Department,Renmin Hospital,Wuhan University.
    Title Chief physician, Associate professor, Master tutor
    Email liuyuwuda@163.com
    TEL 027-88041911转81038 或13995607375
    Research Direction Regulatory mechanisms, prevention and treatment of ventricular arrhythmias
    Personal Profile He is mainly engaged in the diagnosis and treatment of cardiovascular diseases, and has been awarded 2 items for the National Natural Science Foundation, 1 item for the Natural Science Foundation of Hubei Province, 1 item for the Youth Science Plan for Light of the Morning Sun of Wuhan City, and 1 item for independent scientific research project of Wuhan University. Besides, there are more than 40 articles published in the JACC Cardiovasc Interv, Hypertension, Cardiovasc Res, Europace, J Cardiovasc Electrophysiol, etc by the first author or corresponding author, including more than 30 SCI papers. He was elected as the Luojia Young Scholar of Wuhan University. By now, he has educated 2 masters. At present, there are 2 Masters studying with him.
    Selected Publications 1.He Y, Liu Y (corresponding author), Zhou M, Xie K, Tang Y, Huang H, Huang C. C-type natriuretic peptide suppresses ventricular arrhythmias in rats with acute myocardial ischemia. Peptides. 2020 Apr;126:170238.
    2.Zhou M, Liu Y (corresponding author), He Y, Xie K, Quan D, Tang Y, Huang H, Huang C. Selective chemical ablation of transient receptor potential vanilloid 1 expressing neurons in the left stellate ganglion protects against ischemia-induced ventricular arrhythmias in dogs. Biomed Pharmacother. 2019 Dec;120:109500.
    3.Zhou M, Liu Y (corresponding author), Xiong L, Quan D, He Y, Tang Y, Huang H, Huang C. Cardiac Sympathetic Afferent Denervation Protects Against Ventricular Arrhythmias by Modulating Cardiac Sympathetic Nerve Activity During Acute Myocardial Infarction. Med Sci Monit. 2019 Mar 16;25:1984-1993.
    4.Xiong L, Liu Y (corresponding author), Zhou M, Wang G, Quan D, Shen C, Shuai W, Kong B, Huang C, Huang H. Targeted ablation of cardiac sympathetic neurons improves ventricular electrical remodelling in a canine model of chronic myocardial infarction. Europace. 2018 Dec 1;20(12):2036-2044.
    5.Xiong L, Liu Y  (corresponding author), Zhou M, Wang G, Quan D, Shuai W,  Shen C, Kong B, Huang C, Huang H. Targeted ablation of cardiac sympathetic neurons attenuates adverse post-infarction remodelling and left ventricular dysfunction. Exp Physiol. 2018 Sep;103(9):1221-1229.
    6.Huang H, Liu Y (co-first author), Xu Y, Wang Z, Li Y, Cao K, Zhang S, Yang Y, Yang X, Huang D, Yu B, Su X, Wu L, Huang C. Percutaneous Left Atrial Appendage Closure With the LAmbre Device for Stroke Prevention in Atrial Fibrillation: A Prospective, Multicenter Clinical Study. JACC Cardiovasc Interv. 2017;10(21):2188-2194.
    7.Peng J, Liu Y (co-first author), Xiong X, Huang C, Mei Y, Wang Z, Tang Y, Ye J, Kong B, Liu W, Wang T, Huang H. Loss of MD1 exacerbates pressure overload-induced left ventricular structural and electrical remodelling. Sci Rep. 2017;7(1):5116.
    8.Liu Y, Scherlag BJ, Fan Y, Xia W, Huang H, Po SS. Acetylcholine-Atropine Interactions: Paradoxical Effects on Atrial Fibrillation Inducibility. J Cardiovasc Pharmacol. 2017;69(6):369-373. 
    9.Xiong X, Liu Y (co-first author), Mei Y, Peng J, Wang Z, Kong B, Zhong P, Xiong L, Quan D, Li Q, Wang G, Huang H. Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling. Sci Rep. 2017;7:41857.
    10.Wu G, Liu Y (co-first author), Huang H, Tang Y, Liu W, Mei Y, Wan N, Liu X, Huang C. SH2B1 is critical for the regulation of cardiac remodelling in response to pressure overload. Cardiovasc Res. 2015;107(2):203-15.
    11.Liu W, Liu Y (co-first author), Zhang Y, Zhu X, Zhang R, Guan L, Tang Q, Jiang H, Huang C, Huang H. MicroRNA-150 Protects Against Pressure Overload-Induced Cardiac Hypertrophy. J Cell Biochem. 2015;116(10):2166-76.
    12.Liu Y, Li H, Xia W, Yu S, Huang C, Huang H. Electrophysiological effect of rotigaptide in rabbits with heart failure. Arch Med Sci. 2014;10(2):374-80. 
    13.Zhang Y, Liu Y (co-first author), Zhu XH, Zhang XD, Jiang DS, Bian ZY, Zhang XF, Chen K, Wei X, Gao L, Zhu LH, Yang Q, Fan GC, Lau WB, Ma X, Li H. Dickkopf-3 attenuates pressure overload-induced cardiac remodelling. Cardiovasc Res. 2014;102(1):35-45.
    14.Jiang DS, Liu Y (co-first author), Zhou H, Zhang Y, Zhang XD, Zhang XF, Chen K, Gao L, Peng J, Gong H, Chen Y, Yang Q, Liu PP, Fan GC, Zou Y, Li H. Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy. Hypertension. 2014;63(4):713-22.
    15.Liu Y, Huang H, Zhang Y, Zhu XY, Zhang R, Guan LH, Tang Q, Jiang H, Huang C. Regulator of G protein signaling 3 protects against cardiac hypertrophy in mice. J Cell Biochem. 2014;115(5):977-86. 
    16.Liu Y, Jiang XL, Liu Y (co-first author), Jiang DS, Zhang Y, Zhang R, Chen Y, Yang Q, Zhang XD, Fan GC, Li H. Toll-interacting protein (Tollip) negatively regulates pressure overload-induced ventricular hypertrophy in mice. Cardiovasc Res. 2014;101(1):87-96.
    17.Liu Y, Scherlag BJ, Fan Y, Mao J, Hepler E, Varma V, Male S, Xia W, Huang H, Po SS. Experimental model of focal atrial tachycardia: clinical correlates. J Cardiovasc Electrophysiol. 2013;24(8):909-13.
    18.Liu Y, Scherlag BJ, Fan Y, Varma V, Male S, Chaudhry MA, Huang C, Po SS. Inducibility of atrial fibrillation after GP ablations and "autonomic blockade": evidence for the pathophysiological role of the nonadrenergic and noncholinergic neurotransmitters. J Cardiovasc Electrophysiol. 2013;24(2):188-95.
    19.Liu Y, Scherlag BJ, Yagi T, Patterson E, Jackman WM, Lazzara R, Po SS. Extra- and intracellular recordings from the avjunction: discerning the mechanisms for irregular ventricular responses during supraventricular arrhythmias. Acta Cardiol. 2012;67(2):221-9.
    20.Liu Y, Huang H, Xia W, Tang Y, Li H, Huang C. NADPH oxidase inhibition ameliorates cardiac dysfunction in rabbits with heart failure. Mol Cell Biochem. 2010;343(1-2):143-53.