赵庆彦
心内
心内三科副主任，房颤中心副主任，教授，二级主任医师，博士生导师
心内三科副主任，房颤中心副主任，教授，二级主任医师，博士生导师
导师介绍
| 姓名 | 赵庆彦 |
| 出生年月 | 1971年3月 |
| 单位 | 武汉大学人民医院心血管内科 |
| 所属学科 | 临床医学-内科学 |
| 职务、职称及头衔 | 心内三科副主任，房颤中心副主任，教授，二级主任医师，博士生导师 |
| ruyan71@163.com | |
| 联系方式 | 027-88041911转81038或13871329139 |
| 研究方向 |
1.心电生理与心律失常：心房颤动的发生机制研究 2. 心律失常的介入诊疗：快速和慢性心律失常的消融和器械植入治疗 |
| 个人简介 | 主要从事心血管疾病的诊治与科研工作，主持国家自然科学基金4项、省科技厅、省教委、省卫生厅等课题5项。获国家科技进步二等奖1项，湖北省科技进步一等奖2项。在Lancet子刊，Hypertension, Eurointervention, Europace, 《中华医学杂志》、《中华心律失常学杂志》等杂志上发表论文200余篇，其中SCI论文65篇，影响因子超过200。已培养博士生5名，硕士生10名。目前正在培养的博士生6名，硕士生7名。 |
| 学术任职与荣誉 |
EHRS学会会员；APHRS起搏学组会员；中国房颤中心联盟左心耳封堵工作委员会委员；中国房颤中心联盟第一届专家委员会委员、委员会委员；湖北省医师协会心律学专业委员会第一届委员会常务委员；中国医院协会心脏康复管理专业委员会第一届委员；中华医学会心电生理和起搏分会、中国医师协会心律学专业委员会第一届中青年电生理工作委员会委员；中华医学会心血管病学分会第十届委员会肺血管病学组委员；全国心血管疾病介入诊疗技术培训项目基地导师；第八届中国生物医学工程学会心律分会青年委员；中华医学会心电生理和起搏分会第六届委员会心房颤动工作委员会委员；抗心律失常药物治疗学组委员；左心耳封堵工作委员会委员；中华中医药学会络病分会第三、四届委员会委员 《中华心血管病杂志》审稿人；《中国心脏起搏与心电生理杂志》特邀审稿人 |
| 教育履历 |
1990.09-1995.06新乡医学院临床医学专业本科生获学士学位 2001.09-2003.06武汉大学第一临床学院内科学硕士研究生获硕士学位 2003.09-2006.06武汉大学第一临床学院内科学博士研究生获博士学位 |
| 工作履历 |
1995.07-2001.08 河南省安阳地区医院住院医师 2006.07-2008.12 武汉大学人民医院心血管内科主治医师 2009.01-2012.12 武汉大学人民医院心血管内科副教授、副主任医师 2009.06-2009.08 德国Essen西德心脏中心访问学者 2011.07-2011.08 美国Oklahoma大学访问学者 2012.01-至今 武汉大学人民医院心血管内科主任医师 2016.11-至今 武汉大学人民医院心血管内科教授 |
| 成果获奖 |
1. “心律失常的结构和神经重构的基础研究与临床防治”于2011年获得国家科技进步二等奖 2. “心房颤动的防治策略研究与推广应用”于2014年获得湖北省成果推广一等奖 3. “自主神经与心律失常相关性研究”于2010年获湖北省科技进步一等奖 4. “快速心律失常的基础与临床研究”于2011年获得华夏医学科技一等奖 5.博士论文《迷走神经诱发心房颤动的电生理和离子通道基础研究》于2008年被评为湖北省优秀博士论文，2009年获全国优秀博士论文提名奖 6. 2019年获美国HRS会优秀青年学者奖 |
| 代表性论著 |
1.
Liu D, Yang M, Yao Y, He S, Wang Y, Cao Z, Chen H, Fu Y, Liu H, Zhao Q（通讯作者）. Cardiac Fibroblasts Promote
Ferroptosis in Atrial Fibrillation by Secreting Exo-miR-23a-3p Targeting
SLC7A11. Oxid Med Cell Longev. 2022 May 29;2022:3961495. doi:
10.1155/2022/3961495. 2. Ran Q, Chen X, Zhang C, Wan W, Ye T, Sun Y, Zhao X, Shi S, Yang B, Zhao Q（通讯作者）. Pinocembrin Decreases Atrial Fibrillation Susceptibility in a Rodent Model of Depression. Front Cardiovasc Med. 2022 May 20;9:766477 3. Shi S, Tang Y, Zhao Q（共一）, Yan H, Yu B, Zheng Q, Li Y, Zheng L, Yuan Y, Zhong J, Xu J, Wu Y, Xu J, Chen L, Li S, Jiang J, Wang J, Fan J, Chen M, Tang B, Li W, Wu Q, Shi B, Zhou S, Zhao X, Yin Y, Zhang Z, Zhong G, Han X, Liu F, Wu M, Gao L, Yang B, Huang H, Huang C; China Atrial Fibrillation Center Project Team). Prevalence and risk of atrial fibrillation in China: A national cross-sectional epidemiological study. Lancet Reg Health West Pac. 2022 Apr 11;23:100439. doi: 10.1016/j.lanwpc.2022. 4. Ma Y, Fu Y, Wang Y, Yang M, Yao Y, He S, Liu D, Cao Z, Wang X, Tang Y, Zhao Q（通讯作者），Huang C. Blocking Intermediate-Conductance Calcium-Activated Potassium Channels in the Macrophages Around Ganglionated Plexi Suppresses Atrial Fibrillation Vulnerability in Canines With Rapid Atrial Pacing. Front Physiol. 2022 Apr 1;13:837412. 5. Yao Y, He S, Wang Y, Cao Z, Liu D, Fu Y, Chen H, Wang X, Zhao Q (通讯作者). Blockade of Exosome Release Suppresses Atrial Fibrillation by Alleviating Atrial Fibrosis in Canines With Prolonged Atrial Pacing. Front Cardiovasc Med. 2021 Oct 15;8:699175. doi: 10.3389/fcvm.2021.699175. 6. Liu D, Shi S, Liu X, Ye T, Wang L, Qu C, Yang B, Zhao Q (通讯作者). Retrospective cohort study of new-onset atrial fibrillation in acute pulmonary embolism on prognosis. BMJ Open. 2021;11(9):e047658. doi: 10.1136/bmjopen-2020-047658 7. He S, Wang Y, Yao Y, Cao Z, Yin J, Zi L, Chen H, Fu Y, Wang X, Zhao Q (通讯作者). Inhibition of KCa3.1 Channels Suppresses Atrial Fibrillation via the Attenuation of Macrophage Pro-inflammatory Polarization in a Canine Model With Prolonged Rapid Atrial Pacing. Front Cardiovasc Med. 2021;8:656631. doi: 10.3389/fcvm.2021.656631 8. Wang Y, He S, Xiong X, Liu J, Xie B, Yao Y, Yin J, Zi L, Wang X, Tang Y, Zhao Q (通讯作者). Left Stellate Ganglion Ablation Inhibits Ventricular Arrhythmias through Macrophage Regulation in Canines with Acute Ischemic Stroke. Int J Med Sci. 2021 Jan 1;18(4):891-901. doi: 10.7150/ijms.50976 9. Li L, Zhang S, He B, Chen X, Wang S, Zhao Q (通讯作者). Risk factors and electrocardiogram characteristics for mortality in critical inpatients with COVID-19. Clin Cardiol. 2020;43(12):1624-1630. doi: 10.1002/clc.23492 10. Zhao H, Wang F, Zhang W, Yang M, Tang Y, Wang X, Zhao Q (通讯作者), Huang C. Overexpression of TBX3 in human induced pluripotent stem cells (hiPSCs) increases their differentiation into cardiac pacemaker-like cells. Biomed Pharmacother. 2020;130:110612. doi: 10.1016/j.biopha.2020.110612. 11. Li L, Zhang S, He B, Chen X, Zhao Q (通讯作者). Retrospective Study of Risk Factors for Myocardial Damage in Patients With Critical Coronavirus Disease 2019 in Wuhan. J Am Heart Assoc. 2020; 9(15):e016706. doi: 10.1161/JAHA.120.016706. 12. Yang M, Wang Y, Xiong X, Xie B, Liu J, Yin J, Zi L, Wang X, Tang Y, Huang C, Zhao Q (通讯作者). SK4 calcium-activated potassium channels activated by sympathetic nerves enhances atrial fibrillation vulnerability in a canine model of acute stroke. Heliyon. 2020;6(5):e03928. doi: 10.1016/j.heliyon.2020.e03928. 13. Yang M, Wang Y, Zhao H, Yin J, Zi L, Wang X, Tang Y, Huang C, Zhao Q (通讯作者). Role of intermediate-conductance calcium-activated potassium channels in atrial fibrillation in canines with rapid atrial pacing. J Interv Card Electrophysiol. 2020 Apr 4. doi: 10.1007/s10840-020-00736-8. 14. Wang Y, Xiong X, Xie B, Liu J, Yang M, Yin J, Zi L, Wang X, Tang Y, Huang C, Fu H, Zhao Q (通讯作者). A brain-stellate ganglion-atrium network regulates atrial fibrillation vulnerability through macrophages in acute stroke. Life Sci. 2019 Nov 15;237:116949. 15. Wang Y, Qian Y, Smerin D, Zhang S, Zhao Q (通讯作者), Xiong X. Newly Detected Atrial Fibrillation after Acute Stroke: A Narrative Review of Causes and Implications. Cardiology. 2019;144(3-4):112-121. 16. Yin J, Yang M, Yu S, Fu H, Huang H, Yang B, Liu Y, He B, Bao M, Wu G, Lu Z, Liu H, Liu X, Dong L, Huang C, Zhao Q (通讯作者). Effect of acupuncture at Neiguan point combined with amiodarone therapy on early recurrence after pulmonary vein electrical isolation in patients with persistent atrial fibrillation. J Cardiovasc Electrophysiol. 2019;30(6):910-917. 17. Zhao Q, Zhang S, Zhao H, Zhang S, Dai Z, Qian Y, Zhang Y, Wang X, Tang Y, Huang C. Median nerve stimulation prevents atrial electrical remodelling and inflammation in a canine model with rapid atrial pacing. Europace, 2018; 20: 712-718. 18. Zhao Q, Deng H, Jiang X, et al. Effects of Intrinsic and Extrinsic Cardiac Nerves on Atrial Arrhythmia in Experimental Pulmonary Artery Hypertension[J]. Hypertension,2015,66(5): 1042-1049. 19. Zhao Q, Jiang X, Tang Y, et al. Beneficial Effects of Renal Denervation on Pulmonary Vascular Remodeling in Experimental Pulmonary Artery Hypertension[J]. Rev Esp Cardiol (Engl Ed), 2015,68(7):562-570. 20. Wang X, Huang C, Zhao Q (通讯作者), et al. Effect of renal sympathetic denervation on the progression of paroxysmal atrial fibrillation in canines with long-term intermittent atrial pacing[J]. Europace, 2015,17(4):647-654. |
| Name | QINGYAN ZHAO |
| Date of birth | March，1971 |
| Department | Cardiovascular Department，Renmin Hospital,Wuhan University. |
| Title | Vice director, Professor, doctoral tutor |
| ruyan71@163.com | |
| TEL | 027-88041911-81038 or 13871329139 |
| Research Direction |
1. Electrocardio physiology and arrhythmia：The research in the mechanism of
atrial fibrillation 2. Interventional diagnosis of arrhythmia：Ablation or device implantation for arrhythmia |
| Personal Profile | He is mainly engaged in the diagnosis and treatment of cardiovascular diseases, and has been awarded 4 items for the National Natural Science Foundation, 5 items from the provincial science and Technology Department, the Provincial Education Commission and the Provincial Health Department. There are more than 200 articles published in Lancet,Hypertension, Eurointervention, Europace, the Chinese Journal of Medicine and the Chinese journal of cardiac arrhythmias, including nearly 65 SCI papers with more than 200 influencing factors. By now, he has educated 5 doctors and 10 masters. At present, there are 6 doctors and 7 Masters studying with him. |
| Selected Publications |
1.
Liu D, Yang M, Yao Y, He S, Wang Y, Cao Z, Chen H, Fu Y, Liu H, Zhao Q（通讯作者）. Cardiac Fibroblasts Promote
Ferroptosis in Atrial Fibrillation by Secreting Exo-miR-23a-3p Targeting
SLC7A11. Oxid Med Cell Longev. 2022 May 29;2022:3961495. doi:
10.1155/2022/3961495. 2. Ran Q, Chen X, Zhang C, Wan W, Ye T, Sun Y, Zhao X, Shi S, Yang B, Zhao Q（通讯作者）. Pinocembrin Decreases Atrial Fibrillation Susceptibility in a Rodent Model of Depression. Front Cardiovasc Med. 2022 May 20;9:766477 3. Shi S, Tang Y, Zhao Q（共一）, Yan H, Yu B, Zheng Q, Li Y, Zheng L, Yuan Y, Zhong J, Xu J, Wu Y, Xu J, Chen L, Li S, Jiang J, Wang J, Fan J, Chen M, Tang B, Li W, Wu Q, Shi B, Zhou S, Zhao X, Yin Y, Zhang Z, Zhong G, Han X, Liu F, Wu M, Gao L, Yang B, Huang H, Huang C; China Atrial Fibrillation Center Project Team). Prevalence and risk of atrial fibrillation in China: A national cross-sectional epidemiological study. Lancet Reg Health West Pac. 2022 Apr 11;23:100439. doi: 10.1016/j.lanwpc.2022. 4. Ma Y, Fu Y, Wang Y, Yang M, Yao Y, He S, Liu D, Cao Z, Wang X, Tang Y, Zhao Q（通讯作者），Huang C. Blocking Intermediate-Conductance Calcium-Activated Potassium Channels in the Macrophages Around Ganglionated Plexi Suppresses Atrial Fibrillation Vulnerability in Canines With Rapid Atrial Pacing. Front Physiol. 2022 Apr 1;13:837412. 5. Yao Y, He S, Wang Y, Cao Z, Liu D, Fu Y, Chen H, Wang X, Zhao Q (通讯作者). Blockade of Exosome Release Suppresses Atrial Fibrillation by Alleviating Atrial Fibrosis in Canines With Prolonged Atrial Pacing. Front Cardiovasc Med. 2021 Oct 15;8:699175. doi: 10.3389/fcvm.2021.699175. 6. Liu D, Shi S, Liu X, Ye T, Wang L, Qu C, Yang B, Zhao Q (通讯作者). Retrospective cohort study of new-onset atrial fibrillation in acute pulmonary embolism on prognosis. BMJ Open. 2021;11(9):e047658. doi: 10.1136/bmjopen-2020-047658 7. He S, Wang Y, Yao Y, Cao Z, Yin J, Zi L, Chen H, Fu Y, Wang X, Zhao Q (通讯作者). Inhibition of KCa3.1 Channels Suppresses Atrial Fibrillation via the Attenuation of Macrophage Pro-inflammatory Polarization in a Canine Model With Prolonged Rapid Atrial Pacing. Front Cardiovasc Med. 2021;8:656631. doi: 10.3389/fcvm.2021.656631 8. Wang Y, He S, Xiong X, Liu J, Xie B, Yao Y, Yin J, Zi L, Wang X, Tang Y, Zhao Q (通讯作者). Left Stellate Ganglion Ablation Inhibits Ventricular Arrhythmias through Macrophage Regulation in Canines with Acute Ischemic Stroke. Int J Med Sci. 2021 Jan 1;18(4):891-901. doi: 10.7150/ijms.50976 9. Li L, Zhang S, He B, Chen X, Wang S, Zhao Q (通讯作者). Risk factors and electrocardiogram characteristics for mortality in critical inpatients with COVID-19. Clin Cardiol. 2020;43(12):1624-1630. doi: 10.1002/clc.23492 10. Zhao H, Wang F, Zhang W, Yang M, Tang Y, Wang X, Zhao Q (通讯作者), Huang C. Overexpression of TBX3 in human induced pluripotent stem cells (hiPSCs) increases their differentiation into cardiac pacemaker-like cells. Biomed Pharmacother. 2020;130:110612. doi: 10.1016/j.biopha.2020.110612. 11. Li L, Zhang S, He B, Chen X, Zhao Q (通讯作者). Retrospective Study of Risk Factors for Myocardial Damage in Patients With Critical Coronavirus Disease 2019 in Wuhan. J Am Heart Assoc. 2020; 9(15):e016706. doi: 10.1161/JAHA.120.016706. 12. Yang M, Wang Y, Xiong X, Xie B, Liu J, Yin J, Zi L, Wang X, Tang Y, Huang C, Zhao Q (通讯作者). SK4 calcium-activated potassium channels activated by sympathetic nerves enhances atrial fibrillation vulnerability in a canine model of acute stroke. Heliyon. 2020;6(5):e03928. doi: 10.1016/j.heliyon.2020.e03928. 13. Yang M, Wang Y, Zhao H, Yin J, Zi L, Wang X, Tang Y, Huang C, Zhao Q (通讯作者). Role of intermediate-conductance calcium-activated potassium channels in atrial fibrillation in canines with rapid atrial pacing. J Interv Card Electrophysiol. 2020 Apr 4. doi: 10.1007/s10840-020-00736-8. 14. Wang Y, Xiong X, Xie B, Liu J, Yang M, Yin J, Zi L, Wang X, Tang Y, Huang C, Fu H, Zhao Q (通讯作者). A brain-stellate ganglion-atrium network regulates atrial fibrillation vulnerability through macrophages in acute stroke. Life Sci. 2019 Nov 15;237:116949. 15. Wang Y, Qian Y, Smerin D, Zhang S, Zhao Q (通讯作者), Xiong X. Newly Detected Atrial Fibrillation after Acute Stroke: A Narrative Review of Causes and Implications. Cardiology. 2019;144(3-4):112-121. 16. Yin J, Yang M, Yu S, Fu H, Huang H, Yang B, Liu Y, He B, Bao M, Wu G, Lu Z, Liu H, Liu X, Dong L, Huang C, Zhao Q (通讯作者). Effect of acupuncture at Neiguan point combined with amiodarone therapy on early recurrence after pulmonary vein electrical isolation in patients with persistent atrial fibrillation. J Cardiovasc Electrophysiol. 2019;30(6):910-917. 17. Zhao Q, Zhang S, Zhao H, Zhang S, Dai Z, Qian Y, Zhang Y, Wang X, Tang Y, Huang C. Median nerve stimulation prevents atrial electrical remodelling and inflammation in a canine model with rapid atrial pacing. Europace, 2018; 20: 712-718. 18. Zhao Q, Deng H, Jiang X, et al. Effects of Intrinsic and Extrinsic Cardiac Nerves on Atrial Arrhythmia in Experimental Pulmonary Artery Hypertension[J]. Hypertension,2015,66(5): 1042-1049. 19. Zhao Q, Jiang X, Tang Y, et al. Beneficial Effects of Renal Denervation on Pulmonary Vascular Remodeling in Experimental Pulmonary Artery Hypertension[J]. Rev Esp Cardiol (Engl Ed), 2015,68(7):562-570. 20. Wang X, Huang C, Zhao Q (通讯作者), et al. Effect of renal sympathetic denervation on the progression of paroxysmal atrial fibrillation in canines with long-term intermittent atrial pacing[J]. Europace, 2015,17(4):647-654. |
武汉大学人民医院
湖北省人民医院